{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:36:19Z","timestamp":1784543779399,"version":"3.55.0"},"reference-count":32,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2017.5158","type":"journal-article","created":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T09:06:52Z","timestamp":1505984812000},"source":"Crossref","is-referenced-by-count":2,"title":["Serological evaluation of antigen Tp0693 for diagnosis of syphilis"],"prefix":"10.3892","author":[{"given":"Li","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Laboratory, The First People's Hospital of Changde Affiliated to The University of South China, Changde, Hunan 415000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meixia","family":"Deng","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Institute of Pathogenic Biology, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Institute of Pathogenic Biology, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Yuebei People's Hospital, Shaoguan, Guangdong 512026, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Liu","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Institute of Pathogenic Biology, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Luo","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Institute of Pathogenic Biology, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Medical College, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Medical College, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feijun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Institute of Pathogenic Biology, University of South China, Hengyang, Hunan 421001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2017,9,21]]},"reference":[{"key":"key20200713142526_b1-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1136\/sextrans-2015-052247","article-title":"Secondary syphilis presenting with aortitis and coronary ostial occlusion","volume":"92","author":"Chadwick","year":"2016","journal-title":"Sex Transm Infect"},{"key":"key20200713142526_b2-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.mpmed.2014.04.002","article-title":"Syphilis","volume":"42","author":"Sukthankar","year":"2014","journal-title":"Medicine"},{"key":"key20200713142526_b3-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"363","DOI":"10.15698\/mic2016.09.523","article-title":"Syphilis: Re-emergence of an old foe","volume":"3","author":"Stamm","year":"2016","journal-title":"Microb Cell"},{"key":"key20200713142526_b4-etm-0-0-5158","volume-title":"Prevalence and incidence of selected sexually transmitted infections. Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis and Trichomonas vaginalis: Methods and results used by WHO to generate 2005 estimates","author":"World Health Organization","year":"2011"},{"key":"key20200713142526_b5-etm-0-0-5158","volume-title":"Global prevalence and incidence of selected curable sexually transmitted infections: Overview and estimates","author":"World Health Organization","year":"2001"},{"key":"key20200713142526_b6-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"1658","DOI":"10.1056\/NEJMp0911149","article-title":"Syphilis and social upheaval in China","volume":"362","author":"Tucker","year":"2010","journal-title":"N Engl J Med"},{"key":"key20200713142526_b7-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1097\/QCO.0b013e32834204bf","article-title":"China's syphilis epidemic: Epidemiology, proximate determinants of spread, and control responses","volume":"24","author":"Tucker","year":"2011","journal-title":"Curr Opin Infect Dis"},{"key":"key20200713142526_b8-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.nurpra.2014.10.020","article-title":"Syphilis on the Rise: Diagnosis, treatment and prevention","volume":"11","author":"Klein","year":"2015","journal-title":"J Nurse Pract"},{"key":"key20200713142526_b9-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.clinmicnews.2010.03.006","article-title":"Changing algorithms in syphilis laboratory diagnosis","volume":"32","author":"Zanto","year":"2010","journal-title":"Clin Microbiol Newsl"},{"key":"key20200713142526_b10-etm-0-0-5158","first-page":"1","article-title":"Centers for Disease Control and Prevention: Sexually transmitted diseases treatment guidelines, 2015","volume":"64","author":"Workowski","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"key20200713142526_b11-etm-0-0-5158","first-page":"1","volume":"106","author":"Morales-M\u00fanera","year":"2015","journal-title":"Update on the diagnosis and treatment of RR-S\u00edfilis: Actualizaci\u00f3n en el manejo diagn\u00f3stico y terap\u00e9utico"},{"key":"key20200713142526_b12-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.intimp.2014.03.011","article-title":"Characterization of the classical biological false-positive reaction in the serological test for syphilis in the modern era","volume":"20","author":"Liu","year":"2014","journal-title":"Int Immunopharmacol"},{"key":"key20200713142526_b13-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.disamonth.2016.03.012","article-title":"Syphilis","volume":"62","author":"Eickhoff","year":"2016","journal-title":"Dis Mon"},{"key":"key20200713142526_b14-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1515\/CCLM.2009.071","article-title":"Sensitive and specific ELISA coated by TpN15-TpN17-TpN47 fusion protein for detection of antibodies to Treponema pallidum","volume":"47","author":"Sun","year":"2009","journal-title":"Clin Chem Lab Med"},{"key":"key20200713142526_b15-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1089\/153685903771797101","article-title":"Monoclonal antibodies to the recombinant protein TmpA of the Treponema pallidum","volume":"22","author":"Moreno","year":"2003","journal-title":"Hybrid Hybridomics"},{"key":"key20200713142526_b16-etm-0-0-5158","doi-asserted-by":"crossref","first-page":"720","DOI":"10.4049\/jimmunol.157.2.720","article-title":"Molecular mimicry between an immunodominant amino acid motif on the 47-kDa lipoprotein of Treponema pallidum (Tpp47) and multiple repeats of analogous sequences in fibronectin","volume":"157","author":"Baughn","year":"1996","journal-title":"J Immunol"},{"key":"key20200713142526_b17-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1128\/CMR.19.1.29-49.2006","article-title":"Biological basis for syphilis","volume":"19","author":"Lafond","year":"2006","journal-title":"Clin Microbiol Rev"},{"key":"key20200713142526_b18-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"4445","DOI":"10.1128\/IAI.73.7.4445-4450.2005","article-title":"Genome scale identification of Treponema pallidum antigens","volume":"73","author":"McKevitt","year":"2005","journal-title":"Infect Immun"},{"key":"key20200713142526_b19-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.actatropica.2016.05.010","article-title":"Evaluation of Leishmania (Leishmania) infantum excreted-secretion antigens for detection of canine leishmaniasis","volume":"161","author":"Pinedo-Cancino","year":"2016","journal-title":"Acta Trop"},{"key":"key20200713142526_b20-etm-0-0-5158","first-page":"18","article-title":"Role of alpha-crystallin, early-secretion antigenic target 6-kDa protein and culture filtrate protein 10 as novel diagnostic markers in osteoarticular tuberculosis","volume":"6","author":"Rizvi","year":"2016","journal-title":"J Ortho Trans"},{"key":"key20200713142526_b21-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.ijvsm.2014.10.002","article-title":"Diagnosis of Fasciola infection by SDS-PAGE eluted excretory secretory (ES) protein fractions using dot-ELISA","volume":"2","author":"Sabry","year":"2014","journal-title":"Int J Vet Sci Med"},{"key":"key20200713142526_b22-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.vetpar.2010.03.034","article-title":"A novel second instar Gasterophilus excretory\/secretory antigen-based ELISA for the diagnosis of gasterophilosis in grazing horses","volume":"171","author":"S\u00e1nchez-Andrade","year":"2010","journal-title":"Vet Parasitol"},{"key":"key20200713142526_b23-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.ijid.2015.12.013","article-title":"A novel ELISA using a recombinant outer membrane protein, rTp0663, as the antigen for serological diagnosis of syphilis","volume":"43","author":"Xu","year":"2016","journal-title":"Int J Infect Dis"},{"key":"key20200713142526_b24-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1128\/CVI.00122-13","article-title":"Evaluation of the recombinant protein TpF1 of Treponema pallidum for serodiagnosis of syphilis","volume":"20","author":"Jiang","year":"2013","journal-title":"Clin Vaccine Immunol"},{"key":"key20200713142526_b25-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.diagmicrobio.2015.10.005","article-title":"Evaluation of FlaB1, FlaB2, FlaB3, and Tp0463 of Treponema pallidum for serodiagnosis of syphilis","volume":"84","author":"Jiang","year":"2016","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key20200713142526_b26-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.jmii.2015.05.014","article-title":"Fast and efficient detection of tuberculosis antigens using liposome encapsulated secretory proteins of Mycobacterium tuberculosis","volume":"50","author":"Tiwari","year":"2017","journal-title":"J Microbiol Immunol Infect"},{"key":"key20200713142526_b27-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1002\/jcla.21667","article-title":"The diagnostic value and performance evaluation of five serological tests for the detection of Treponema pallidum","volume":"28","author":"Liu","year":"2014","journal-title":"J Clin Lab Anal"},{"key":"key20200713142526_b28-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.1001\/jama.2016.4114","article-title":"Screening for Syphilis: Updated evidence report and systematic review for the US preventive services task force","volume":"315","author":"Cantor","year":"2016","journal-title":"JAMA"},{"key":"key20200713142526_b29-etm-0-0-5158","first-page":"597","article-title":"Evaluation of a chemiluminescent microparticle immunoassay for determination of Treponema pallidum antibodies","volume":"53","author":"Yoshioka","year":"2007","journal-title":"Clin Lab"},{"key":"key20200713142526_b30-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"pii: ftw091","DOI":"10.1093\/femspd\/ftw091","article-title":"The mimic epitopes of Mycobacterium tuberculosis screened by phage display peptide library have serodiagnositic potential for tuberculosis","volume":"74","author":"Wang","year":"2016","journal-title":"Pathog Dis"},{"key":"key20200713142526_b31-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.jinf.2013.03.011","article-title":"Usefulness of IgM-specific enzyme immunoassays for serodiagnosis of syphilis: Comparative evaluation of three different assays","volume":"67","author":"Bosshard","year":"2013","journal-title":"J Infect"},{"key":"key20200713142526_b32-etm-0-0-5158","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.diagmicrobio.2007.04.021","article-title":"Comparison of a Treponema pallidum IgM immunoblot with a 19S fluorescent treponemal antibody absorption test for the diagnosis of congenital syphilis","volume":"59","author":"Herremans","year":"2007","journal-title":"Diagn Microbiol Infect Dis"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T05:44:29Z","timestamp":1693028669000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2017.5158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,21]]},"references-count":32,"URL":"https:\/\/doi.org\/10.3892\/etm.2017.5158","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,21]]}}}