{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T13:42:47Z","timestamp":1775050967048,"version":"3.50.1"},"reference-count":30,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2018.5934","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T07:58:33Z","timestamp":1520495913000},"source":"Crossref","is-referenced-by-count":1,"title":["Pressure ulcer healing promoted by adequate protein intake in rats"],"prefix":"10.3892","author":[{"given":"Zhanfen","family":"Qin","sequence":"first","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Second General Surgery Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiqing","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujuan","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nursing, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,3,8]]},"reference":[{"key":"key20200713144827_b1-etm-0-0-5934","first-page":"41","article-title":"Assessing the adequacy of pressure ulcer prevention in Belgian geriatric hospital wards","volume":"19","author":"Defloor","year":"2010","journal-title":"J Clin Nurs"},{"key":"key20200713144827_b2-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1111\/j.1747-0080.2011.01536.x","article-title":"Use of an arginine-enriched oral nutrition supplement in the healing of pressure ulcers in patients with spinal cord injuries: An observational study","volume":"68","author":"Chapman","year":"2011","journal-title":"Nutr Diet"},{"key":"key20200713144827_b3-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.arr.2005.03.005","article-title":"Enteral nutritional support in prevention and treatment of pressure ulcers: A systematic review and meta-analysis","volume":"4","author":"Stratton","year":"2005","journal-title":"Ageing Res Rev"},{"key":"key20200713144827_b4-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/S0261-5614(03)00039-6","article-title":"A randomised, double-blind assessment of the effect of nutritional supplementation on the prevention of pressure ulcers in hip-fracture patients","volume":"22","author":"Houwing","year":"2003","journal-title":"Clin Nutr"},{"key":"key20200713144827_b5-etm-0-0-5934","first-page":"164","article-title":"Survey of nutritional status in newly hospitalized patients with stage III or stage IV pressure ulcers","volume":"13","author":"Guenter","year":"2000","journal-title":"Adv Skin Wound Care"},{"issue":"476\u2013478","key":"key20200713144827_b6-etm-0-0-5934","first-page":"480","article-title":"Benefits of an oral nutritional supplement on pressure ulcer healing in long-term care residents","volume":"17","author":"Heyman","year":"2008","journal-title":"J Wound Care"},{"key":"key20200713144827_b7-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0167-4943(01)00120-0","article-title":"Impact on pressure ulcer healing of an arginine-enriched nutritional solution in patients with severe cognitive impairment","volume":"7","author":"Benati","year":"2001","journal-title":"Arch Gerontol Geriatr Suppl"},{"key":"key20200713144827_b8-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/j.1532-5415.1993.tb06940.x","article-title":"The importance of dietary protein in healing pressure ulcers","volume":"41","author":"Breslow","year":"1993","journal-title":"J Am Geriatr Soc"},{"key":"key20200713144827_b9-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/wrr.12131","article-title":"Leask, CCN2 expression by fibroblasts is not required for cutaneous tissue repair","volume":"22","author":"Liu","year":"2014","journal-title":"Wound Repair Regen"},{"key":"key20200713144827_b10-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1111\/iwj.12343","article-title":"Activated protein C to heal pressure ulcers","volume":"13","author":"Wijewardena","year":"2016","journal-title":"Int Wound J"},{"key":"key20200713144827_b11-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"612","DOI":"10.12968\/jowc.2012.21.12.612","article-title":"Effect of amelogenin ECM protein on the healing of chronic leg ulcers with atrophie blanche","volume":"21","author":"Fogh","year":"2012","journal-title":"J Wound Care"},{"key":"key20200713144827_b12-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/BF03179348","article-title":"A literature review of different pressure ulcer models from 1942\u20132005 and the development of an ideal animal model","volume":"31","author":"Nguyen","year":"2008","journal-title":"Australas Phys Eng Sci Med"},{"key":"key20200713144827_b13-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1080\/10790268.2007.11753921","article-title":"Animal models in pressure ulcer research","volume":"30","author":"Salcido","year":"2007","journal-title":"J Spinal Cord Med"},{"key":"key20200713144827_b14-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/j.1524-475X.2009.00502.x","article-title":"A chronic pressure ulcer model in the nude mouse","volume":"17","author":"Wassermann","year":"2009","journal-title":"Wound Repair Regen"},{"key":"key20200713144827_b15-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1097\/00129334-200501000-00016","article-title":"National Pressure Ulcer Advisory Panel: Pressure-related deep tissue injury under intact skin and the current pressure ulcer staging systems","volume":"18","author":"Ankrom","year":"2005","journal-title":"Adv Skin Wound Care"},{"key":"key20200713144827_b16-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1097\/01.ASW.0000269314.23015.e9","article-title":"National Pressure Ulcer Advisory Panel: National Pressure Ulcer Advisory Panel's updated pressure ulcer staging system","volume":"20","author":"Black","year":"2007","journal-title":"Adv Skin Wound Care"},{"key":"key20200713144827_b17-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1177\/088453360101600505","article-title":"Clinical observations: Nutritional status, nutrition, and pressure ulcers","volume":"16","author":"Mathus-Vliegen","year":"2001","journal-title":"Nutr Clin Pract"},{"key":"key20200713144827_b18-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1016\/j.nut.2005.01.010","article-title":"Dietary whey protein downregulates fatty acid synthesis in the liver, but upregulates it in skeletal muscle of exercise-trained rats","volume":"21","author":"Morifuji","year":"2005","journal-title":"Nutrition"},{"key":"key20200713144827_b19-etm-0-0-5934","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/978-81-322-2491-4_9","volume-title":"Biomedical Applications of Natural Proteins","author":"Gautam","year":"2015"},{"key":"key20200713144827_b20-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1097\/01.ASW.0000461911.31139.62","article-title":"The role of nutrition for pressure ulcer management: National pressure ulcer advisory panel, European pressure ulcer advisory panel, and pan pacific pressure injury alliance white paper","volume":"28","author":"Posthauer","year":"2015","journal-title":"Adv Skin Wound Care"},{"key":"key20200713144827_b21-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1111\/jgs.12855","article-title":"Nutritional status and pressure ulcers. Risk assessment and estimation in older adults","volume":"62","author":"Malafarina","year":"2014","journal-title":"J Am Geriatr Soc"},{"key":"key20200713144827_b22-etm-0-0-5934","first-page":"R472","article-title":"Study of Braden scale prediction of diagnosis boundary value of pressure ulcer and its risk factors","volume":"14","author":"Guan","year":"2014","journal-title":"J Nurs Adm"},{"key":"key20200713144827_b23-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.jtv.2011.04.001","article-title":"An evaluation of serum albumin and the sub-scores of the Waterlow score in pressure ulcer risk assessment","volume":"20","author":"Anthony","year":"2011","journal-title":"J Tissue Viability"},{"key":"key20200713144827_b24-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1159\/000067148","article-title":"Raising hemoglobin: An opportunity for increasing survival?","volume":"63","author":"Thomas","year":"2002","journal-title":"Oncology"},{"key":"key20200713144827_b25-etm-0-0-5934","first-page":"73","volume-title":"Susceptibility of Spinal Cord-Injured Individuals to Pressure Ulcers","author":"Bogie","year":"2005"},{"key":"key20200713144827_b26-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1017\/S0954422411000084","article-title":"Protein hydrolysates and tissue repair","volume":"24","author":"Thomson","year":"2011","journal-title":"Nutr Res Rev"},{"key":"key20200713144827_b27-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/j.jpeds.2013.09.053","article-title":"50 Years ago in The Journal of Pediatrics: Hypoproteinemia and edema in infants with cystic fibrosis of the pancreas","volume":"164","author":"Palermo","year":"2014","journal-title":"J Pediatr"},{"key":"key20200713144827_b28-etm-0-0-5934","first-page":"521","article-title":"Characteristics and prognosis of pulmonary infection in patients with neurologic disease and hypoproteinemia","volume":"13","author":"Li","year":"2015","journal-title":"Expert Rev Anti Infect Ther"},{"key":"key20200713144827_b29-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"4","DOI":"10.4161\/viru.27372","article-title":"Epidemiology of severe sepsis","volume":"5","author":"Mayr","year":"2014","journal-title":"Virulence"},{"key":"key20200713144827_b30-etm-0-0-5934","doi-asserted-by":"publisher","first-page":"e471","DOI":"10.1097\/GOX.0000000000000443","article-title":"Hyperglycemia interacts with ischemia in a synergistic way on wound repair and myofibroblast differentiation","volume":"3","author":"Tobalem","year":"2015","journal-title":"Plast Reconstr Surg Glob Open"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T13:49:34Z","timestamp":1594648174000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2018.5934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,8]]},"references-count":30,"URL":"https:\/\/doi.org\/10.3892\/etm.2018.5934","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,8]]}}}