{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T09:11:55Z","timestamp":1723021915442},"reference-count":26,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7256","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T09:16:45Z","timestamp":1549963005000},"source":"Crossref","is-referenced-by-count":4,"title":["miRNA\u2011125a modulates autophagy of thyroiditis through PI3K\/Akt\/mTOR signaling pathway"],"prefix":"10.3892","author":[{"given":"Danyan","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huacong","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongxi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binghan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,2,12]]},"reference":[{"key":"key20200713120322_b1-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"e0146455","DOI":"10.1371\/journal.pone.0146455","article-title":"Effect of immunotherapy on seizure outcome in patients with autoimmune encephalitis: A prospective observational registry study","volume":"11","author":"Byun","year":"2016","journal-title":"PLoS One"},{"key":"key20200713120322_b2-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/1745-6215-15-115","article-title":"The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): Study protocol for a randomized controlled trial","volume":"15","author":"Winther","year":"2014","journal-title":"Trials"},{"key":"key20200713120322_b3-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1530\/EJE-16-0548","article-title":"Effects of levothyroxine treatment on pregnancy outcomes in pregnant women with autoimmune thyroid disease","volume":"176","author":"Nazarpour","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"key20200713120322_b4-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"E540","DOI":"10.3390\/ijms18030540","article-title":"Expression of autophagy-related proteins in different types of thyroid cancer","volume":"18","author":"Kim","year":"2017","journal-title":"Int J Mol Sci"},{"key":"key20200713120322_b5-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.mce.2017.02.018","article-title":"Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy","volume":"458","author":"Singh","year":"2017","journal-title":"Mol Cell Endocrinol"},{"key":"key20200713120322_b6-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1158\/1541-7786.MCR-10-0162","article-title":"Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer","volume":"8","author":"Lin","year":"2010","journal-title":"Mol Cancer Res"},{"key":"key20200713120322_b7-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.biopha.2016.06.014","article-title":"Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K\/Akt\/mTOR and NF-\u03baB signal pathways in thyroid carcinoma cells","volume":"83","author":"Kim","year":"2016","journal-title":"Biomed Pharmacother"},{"key":"key20200713120322_b8-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"E804","DOI":"10.1210\/jc.2013-3101","article-title":"Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkarla and Pten in mice","volume":"99","author":"Pringle","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"key20200713120322_b9-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1517\/14728222.2011.594044","article-title":"The mTOR protein as a target in thyroid cancer","volume":"15","author":"Souza","year":"2011","journal-title":"Expert Opin Ther Targets"},{"key":"key20200713120322_b10-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/j.ctrv.2015.06.005","article-title":"PI3K\/Akt\/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma","volume":"41","author":"Petrulea","year":"2015","journal-title":"Cancer Treat Rev"},{"key":"key20200713120322_b11-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jim.2016.10.002","article-title":"MicroRNA mediated network motifs in autoimmune diseases and its crosstalk between genes, functions and pathways","volume":"440","author":"Prabahar","year":"2017","journal-title":"J Immunol Methods"},{"key":"key20200713120322_b12-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1515\/cclm-2016-0449","article-title":"Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases","volume":"55","author":"Otsu","year":"2017","journal-title":"Clin Chem Lab Med"},{"key":"key20200713120322_b13-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"631","DOI":"10.7754\/Clin.Lab.2015.150812","article-title":"Elevated serum inflammatory cytokines in lupus nephritis patients, in association with promoted hsa-miR-125a","volume":"62","author":"Li","year":"2016","journal-title":"Clin Lab"},{"key":"key20200713120322_b14-etm-0-0-7256","first-page":"453","article-title":"miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K\/AKT signaling pathway","volume":"42","author":"Hu","year":"2018","journal-title":"Int J Mol Med"},{"key":"key20200713120322_b15-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20200713120322_b16-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"4049","DOI":"10.3892\/etm.2016.3854","article-title":"Anti-inflammatory effects of luteolin on experimental autoimmune thyroiditis in mice","volume":"12","author":"Xia","year":"2016","journal-title":"Exp Ther Med"},{"key":"key20200713120322_b17-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.2337\/dc13-1890","article-title":"Self-reported autoimmune disease by sex in the diabetes control and complications trial\/epidemiology of diabetes interventions and complications (DCCT\/EDIC) study","volume":"37","author":"Buschur","year":"2014","journal-title":"Diabetes Care"},{"key":"key20200713120322_b18-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1007\/s10103-012-1129-9","article-title":"Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: A randomized, placebo-controlled clinical trial","volume":"28","author":"H\u00f6fling","year":"2013","journal-title":"Lasers Med Sci"},{"key":"key20200713120322_b19-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"79117","DOI":"10.18632\/oncotarget.12997","article-title":"Defective ciliogenesis in thyroid h\u00fcrthle cell tumors is associated with increased autophagy","volume":"7","author":"Lee","year":"2016","journal-title":"Oncotarget"},{"key":"key20200713120322_b20-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jaut.2016.07.008","article-title":"Excess iodine promotes apoptosis of thyroid follicular epithelial cells by inducing autophagy suppression and is associated with Hashimoto thyroiditis disease","volume":"75","author":"Xu","year":"2016","journal-title":"J Autoimmun"},{"key":"key20200713120322_b21-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"5355","DOI":"10.4049\/jimmunol.1402557","article-title":"MicroRNA-125a inhibits autophagy activation and antimicrobial responses during mycobacterial infection","volume":"194","author":"Kim","year":"2015","journal-title":"J Immunol"},{"key":"key20200713120322_b22-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.freeradbiomed.2012.09.003","article-title":"Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2","volume":"56","author":"Raad","year":"2013","journal-title":"Free Radic Biol Med"},{"key":"key20200713120322_b23-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.imbio.2014.03.009","article-title":"Polymorphism of the NFKB1 affects the serum inflammatory levels of IL-6 in Hashimoto thyroiditis in a Turkish population","volume":"219","author":"Koc","year":"2014","journal-title":"Immunobiology"},{"key":"key20200713120322_b24-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.gene.2017.03.014","article-title":"Thyroid hormone induce a p53-dependent DNA damage through PI3K\/Akt activation in sperm","volume":"615","author":"Xian","year":"2017","journal-title":"Gene"},{"key":"key20200713120322_b25-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.mce.2016.12.007","article-title":"GPER\/ERK&AKT\/NF-\u03baB pathway is involved in cadmium-induced proliferation, invasion and migration of GPER-positive thyroid cancer cells","volume":"442","author":"Zhu","year":"2017","journal-title":"Mol Cell Endocrinol"},{"key":"key20200713120322_b26-etm-0-0-7256","doi-asserted-by":"publisher","first-page":"681","DOI":"10.3892\/ol.2015.3264","article-title":"miR-125a inhibits the migration and invasion of liver cancer cells via suppression of the PI3K\/AKT\/mTOR signaling pathway","volume":"10","author":"Tang","year":"2015","journal-title":"Oncol Lett"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T11:30:52Z","timestamp":1594639852000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,12]]},"references-count":26,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7256","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,12]]}}}