{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:35:26Z","timestamp":1774614926833,"version":"3.50.1"},"reference-count":43,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7300","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T11:24:16Z","timestamp":1550834656000},"source":"Crossref","is-referenced-by-count":7,"title":["The risk factors of portal vein thrombosis in patients with liver cirrhosis"],"prefix":"10.3892","author":[{"given":"Yasir","family":"Cagin","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilmaz","family":"Bilgic","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lhami","family":"Berber","sequence":"additional","affiliation":[{"name":"Clinic of Hematology, Malatya Training and Education Hospital, 44330 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oguzhan","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Erdogan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feyza","family":"Firat","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cemil","family":"Colak","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuksel","family":"Seckin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Harputluoglu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Medical Faculty, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,2,22]]},"reference":[{"key":"key20200713120539_b1-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.jhep.2004.01.001","article-title":"Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis","volume":"40","author":"Amitrano","year":"2004","journal-title":"J Hepatol"},{"key":"key20200713120539_b2-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1002\/hep.27546","article-title":"Causes and consequences of portal vein thrombosis in 1,243 patients with cirrhosis: Results of a longitudinal study","volume":"61","author":"Nery","year":"2015","journal-title":"Hepatology"},{"key":"key20200713120539_b3-etm-0-0-7300","first-page":"260","article-title":"A single hospital study on portal vein thrombosis in cirrhotic patients-clinical characteristics & risk factors","volume":"139","author":"Chen","year":"2014","journal-title":"Indian J Med Res"},{"key":"key20200713120539_b4-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s11739-008-0128-0","article-title":"Portal vein thrombosis in liver cirrhosis","volume":"3","author":"Fimognari","year":"2008","journal-title":"Intern Emerg Med"},{"key":"key20200713120539_b5-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.3748\/wjg.v12.i13.2115","article-title":"Portal vein thrombosis: Prevalence, patient characteristics and lifetime risk: A population study based on 23796 consecutive autopsies","volume":"12","author":"Ogren","year":"2006","journal-title":"World J Gastroenterol"},{"key":"key20200713120539_b6-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/hep.510310213","article-title":"Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis","volume":"31","author":"Amitrano","year":"2000","journal-title":"Hepatology"},{"key":"key20200713120539_b7-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.jhep.2011.12.034","article-title":"Portal vein thrombosis, cirrhosis, and liver transplantation","volume":"57","author":"Francoz","year":"2012","journal-title":"J Hepatol"},{"key":"key20200713120539_b8-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1111\/j.1538-7836.2011.04429.x","article-title":"Hypercoagulability in cirrhosis: Causes and consequences","volume":"9","author":"Tripodi","year":"2011","journal-title":"J Thromb Haemost"},{"key":"key20200713120539_b9-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1111\/apt.13019","article-title":"Review article: Portal vein obstruction-epidemiology, pathogenesis, natural history, prognosis and treatment","volume":"41","author":"Kumar","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"key20200713120539_b10-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.thromres.2010.09.019","article-title":"Thrombophilic dimension of Budd chiari syndrome and portal venous thrombosis-a concise review","volume":"127","author":"Shetty","year":"2011","journal-title":"Thromb Res"},{"key":"key20200713120539_b11-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/lt.21941","article-title":"Portal vein thrombosis and survival in patients with cirrhosis","volume":"16","author":"Englesbe","year":"2010","journal-title":"Liver Transpl"},{"key":"key20200713120539_b12-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.jceh.2013.12.003","article-title":"Portal vein thrombosis in cirrhosis","volume":"4","author":"Raja","year":"2014","journal-title":"J Clin Exp Hepatol"},{"key":"key20200713120539_b13-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"S100","DOI":"10.1016\/j.jhep.2004.11.015","article-title":"Assessment of the prognosis of cirrhosis: Child-Pugh versus MELD","volume":"42","author":"Durand","year":"2005","journal-title":"J Hepatol"},{"key":"key20200713120539_b14-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"5014","DOI":"10.3748\/wjg.v18.i36.5014","article-title":"What we should know about portal vein thrombosis in cirrhotic patients: A changing perspective","volume":"18","author":"Ponziani","year":"2012","journal-title":"World J Gastroenterol"},{"key":"key20200713120539_b15-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1471-230X-11-66","article-title":"High incidence of hepatitis B infection-associated cirrhosis and hepatocellular carcinoma in the Southeast Asian patients with portal vein thrombosis","volume":"11","author":"Lertpipopmetha","year":"2011","journal-title":"BMC Gastroenterol"},{"key":"key20200713120539_b16-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1097\/SLA.0b013e3181bdf8ad","article-title":"Impact of antithrombin III concentrates on portal vein thrombosis after splenectomy in patients with liver cirrhosis and hypersplenism","volume":"251","author":"Kawanaka","year":"2010","journal-title":"Ann Surg"},{"key":"key20200713120539_b17-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1038\/ncpgasthep0577","article-title":"Nonmalignant portal vein thrombosis in adults","volume":"3","author":"Condat","year":"2006","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"key":"key20200713120539_b18-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1159\/000321886","article-title":"Splenectomy in chronic hepatic disorders: Portal vein thrombosis and improvement of liver function","volume":"28","author":"Ushitora","year":"2011","journal-title":"Dig Surg"},{"key":"key20200713120539_b19-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1111\/j.1440-1746.2011.07040.x","article-title":"Prevalence of the JAK2V617F mutation in Chinese patients with Budd-Chiari syndrome and portal vein thrombosis: A prospective study","volume":"27","author":"Qi","year":"2012","journal-title":"J Gastroenterol Hepatol"},{"key":"key20200713120539_b20-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1111\/j.1440-1746.2009.05921.x","article-title":"Protein C and D-dimer are related to portal vein thrombosis in patients with liver cirrhosis","volume":"25","author":"Zhang","year":"2010","journal-title":"J Gastroenterol Hepatol"},{"key":"key20200713120539_b21-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.3748\/wjg.v18.i15.1834","article-title":"Preoperative predictors of portal vein thrombosis after splenectomy with periesophagogastric devascularization","volume":"18","author":"Zhang","year":"2012","journal-title":"World J Gastroenterol"},{"key":"key20200713120539_b22-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1055\/s-0030-1251501","article-title":"The role of platelets in liver inflammation and regeneration","volume":"36","author":"Lisman","year":"2010","journal-title":"Semin Thromb Hemost"},{"key":"key20200713120539_b23-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1111\/j.1572-0241.2006.00588.x","article-title":"Coagulopathy does not fully protect hospitalized cirrhosis patients from peripheral venous thromboembolism","volume":"101","author":"Northup","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"key20200713120539_b24-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.jhep.2009.03.013","article-title":"Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis development","volume":"51","author":"Zocco","year":"2009","journal-title":"J Hepatol"},{"key":"key20200713120539_b25-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1111\/j.1365-2141.2009.08021.x","article-title":"Haemostasis and thrombosis in liver disease","volume":"148","author":"Roberts","year":"2010","journal-title":"Br J Haematol"},{"key":"key20200713120539_b26-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/01.mbc.0000174080.54871.6b","article-title":"Haemostatic abnormalities in liver disease: Could some haemostatic tests be useful as liver function tests?","volume":"16","author":"Al Ghumlas","year":"2005","journal-title":"Blood Coagul Fibrinolysis"},{"key":"key20200713120539_b27-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/0049-3848(95)91614-Q","article-title":"Hemostasis activation in patients with liver cirrhosis","volume":"77","author":"Vukovich","year":"1995","journal-title":"Thromb Res"},{"key":"key20200713120539_b28-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1378\/chest.09-2177","article-title":"Coagulopathy does not protect against venous thromboembolism in hospitalized patients with chronic liver disease","volume":"137","author":"Dabbagh","year":"2010","journal-title":"Chest"},{"key":"key20200713120539_b29-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1111\/j.1440-1746.2012.07205.x","article-title":"Surgical risk in patients with cirrhosis","volume":"27","author":"Nicoll","year":"2012","journal-title":"J Gastroenterol Hepatol"},{"key":"key20200713120539_b30-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.lab.2005.06.003","article-title":"Evaluation of D-dimer and factor VIII in cirrhotic patients with asymptomatic portal venous thrombosis","volume":"146","author":"Fimognari","year":"2005","journal-title":"J Lab Clin Med"},{"key":"key20200713120539_b31-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/S0168-8278(05)80660-9","article-title":"Value of measurement of mean portal flow velocity by Doppler flowmetry in the diagnosis of portal hypertension","volume":"16","author":"Zironi","year":"1992","journal-title":"J Hepatol"},{"key":"key20200713120539_b32-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1097\/MBC.0b013e328337b3ba","article-title":"Venous thrombosis in patients with chronic liver disease","volume":"21","author":"Anthony Lizarraga","year":"2010","journal-title":"Blood Coagul Fibrinolysis"},{"key":"key20200713120539_b33-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.amjmed.2011.12.004","article-title":"Venous thromboembolism in patients with diabetes mellitus","volume":"125","author":"Piazza","year":"2012","journal-title":"Am J Med"},{"key":"key20200713120539_b34-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"3568","DOI":"10.1016\/S0012-3692(15)52932-2","article-title":"The prevalence of pulmonary embolism and pulmonary hypertension in patients with type II diabetes mellitus","volume":"128","author":"Movahed","year":"2005","journal-title":"Chest"},{"key":"key20200713120539_b35-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1111\/j.1365-2141.2007.06973.x","article-title":"Common risk factors for both arterial and venous thrombosis","volume":"140","author":"Lowe","year":"2008","journal-title":"Br J Haematol"},{"key":"key20200713120539_b36-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1097\/00004836-200001000-00013","article-title":"The role of natural anticoagulant deficiencies and factor V Leiden in the development of idiopathic portal vein thrombosis","volume":"30","author":"Egesel","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"key20200713120539_b37-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1016\/j.cgh.2014.04.026","article-title":"Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis","volume":"12","author":"Qi","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key20200713120539_b38-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1111\/j.1872-034X.2009.00531.x","article-title":"Correlation of routinely used coagulation parameters and presence of portal vein thrombosis in patients with liver cirrhosis","volume":"39","author":"Weber","year":"2009","journal-title":"Hepatol Res"},{"key":"key20200713120539_b39-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.thromres.2012.11.003","article-title":"Coagulation imbalance may not contribute to the development of portal vein thrombosis in patients with cirrhosis","volume":"131","author":"Chen","year":"2013","journal-title":"Thromb Res"},{"key":"key20200713120539_b40-etm-0-0-7300","first-page":"315","article-title":"Portal vein thrombosis in cirrhosis: Diagnosis, natural history, and therapeutic challenges","volume":"31","author":"Mantaka","year":"2018","journal-title":"Ann Gastroenterol"},{"key":"key20200713120539_b41-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1002\/hep.510310307","article-title":"Cause of portal or hepatic venous thrombosis in adults: The role of multiple concurrent factors","volume":"31","author":"Denninger","year":"2000","journal-title":"Hepatology"},{"key":"key20200713120539_b42-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.hpb.2015.10.008","article-title":"Pre-transplant portal vein thrombosis is an independent risk factor for graft loss due to hepatic artery thrombosis in liver transplant recipients","volume":"18","author":"Stine","year":"2016","journal-title":"HPB (Oxford)"},{"key":"key20200713120539_b43-etm-0-0-7300","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1002\/lt.21941","article-title":"Portal vein thrombosis and liver transplant survival benefit","volume":"16","author":"Englesbe","year":"2010","journal-title":"Liver Transpl"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T11:33:34Z","timestamp":1594640014000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,22]]},"references-count":43,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7300","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,22]]}}}