{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:23:10Z","timestamp":1757542990233},"reference-count":25,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7530","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T10:45:36Z","timestamp":1556189136000},"source":"Crossref","is-referenced-by-count":1,"title":["Expression of BMP\u20114 and Smad1 in patients with Hirschsprung disease and its clinical significance"],"prefix":"10.3892","author":[{"given":"Jianjun","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Xuzhou Children's Hospital, Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengli","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Xuzhou Children's Hospital, Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,4,25]]},"reference":[{"key":"key20200713100139_b1-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1053\/j.sempedsurg.2010.03.004","article-title":"Hirschsprung's disease","volume":"19","author":"Kenny","year":"2010","journal-title":"Semin Pediatr Surg"},{"key":"key20200713100139_b2-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00383-009-2402-2","article-title":"Genetic basis of Hirschsprung's disease","volume":"25","author":"Tam","year":"2009","journal-title":"Pediatr Surg Int"},{"key":"key20200713100139_b3-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/nrn2137","article-title":"Enteric nervous system development and Hirschsprung's disease: Advances in genetic and stem cell studies","volume":"8","author":"Heanue","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"key20200713100139_b4-etm-0-0-7530","first-page":"5528","article-title":"Genotyping analysis of 3 RET polymorphisms demonstrates low somatic mutation rate in Chinese Hirschsprung disease patients","volume":"8","author":"Zhang","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"key20200713100139_b5-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1053\/j.sempedsurg.2009.07.003","article-title":"Practical pathology and genetics of Hirschsprung's disease","volume":"18","author":"Kapur","year":"2009","journal-title":"Semin Pediatr Surg"},{"key":"key20200713100139_b6-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1007\/s00335-014-9548-5","article-title":"Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice","volume":"26","author":"Anderson","year":"2015","journal-title":"Mamm Genome"},{"key":"key20200713100139_b7-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"9769","DOI":"10.1038\/srep09769","article-title":"Design, synthesis and inhibitory activity of photoswitchable RET kinase inhibitors","volume":"5","author":"Ferreira","year":"2015","journal-title":"Sci Rep"},{"key":"key20200713100139_b8-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.mcn.2015.06.003","article-title":"The DAF-7\/TGF-\u03b2 signaling pathway regulates abundance of the Caenorhabditis elegans glutamate receptor GLR-1","volume":"67","author":"McGehee","year":"2015","journal-title":"Mol Cell Neurosci"},{"key":"key20200713100139_b9-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.neuron.2014.10.033","article-title":"TGF\u03b2 signaling regulates temporal neurogenesis and potency of neural stem cells in the CNS","volume":"84","author":"Dias","year":"2014","journal-title":"Neuron"},{"key":"key20200713100139_b10-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.lfs.2015.07.016","article-title":"The potential of asiaticoside for TGF-\u03b21\/Smad signaling inhibition in prevention and progression of hypoxia-induced pulmonary hypertension","volume":"137","author":"Wang","year":"2015","journal-title":"Life Sci"},{"key":"key20200713100139_b11-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"13","DOI":"10.2106\/00004623-200300003-00004","article-title":"Smad signaling in mesenchymal and chondroprogenitor cells","author":"Hatakeyama","year":"2003","journal-title":"J Bone Joint Surg Am 85-A"},{"key":"key20200713100139_b12-etm-0-0-7530","first-page":"781","article-title":"Roles of BMP in the development of the central nervous system","volume":"16","author":"Fukuda","year":"2006","journal-title":"Clin Calcium"},{"key":"key20200713100139_b13-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.neuron.2011.12.021","article-title":"Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system","volume":"73","author":"Weng","year":"2012","journal-title":"Neuron"},{"key":"key20200713100139_b14-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1155\/2012\/582107","article-title":"Evaluation of reference genes and normalization strategy for quantitative real-time PCR in human pancreatic carcinoma","volume":"32","author":"Mohelnikova-Duchonova","year":"2012","journal-title":"Dis Markers"},{"key":"key20200713100139_b15-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s11894-013-0340-6","article-title":"Recent developments in Hirschsprung's-associated enterocolitis","volume":"15","author":"Pontarelli","year":"2013","journal-title":"Curr Gastroenterol Rep"},{"key":"key20200713100139_b16-etm-0-0-7530","first-page":"200","article-title":"Concordant expression of Hirschsprung's disease in monozygous twins","volume":"21","author":"Mohammed","year":"2000","journal-title":"Saudi Med J"},{"key":"key20200713100139_b17-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.4103\/0366-6999.183433","article-title":"Novel insights into the pathogenesis of Hirschsprung's-associated enterocolitis","volume":"129","author":"Jiao","year":"2016","journal-title":"Chin Med J (Engl)"},{"key":"key20200713100139_b18-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.bone.2013.08.015","article-title":"BMP9 and COX-2 form an important regulatory loop in BMP9-induced osteogenic differentiation of mesenchymal stem cells","volume":"57","author":"Wang","year":"2013","journal-title":"Bone"},{"key":"key20200713100139_b19-etm-0-0-7530","first-page":"2016","article-title":"Intestinal mucosal barrier is injured by BMP2\/4 via activation of NF-\u03baB signals after ischemic reperfusion","volume":"901530","author":"Chen","year":"2014","journal-title":"Mediators Inflamm"},{"key":"key20200713100139_b20-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.ydbio.2006.04.442","article-title":"Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo","volume":"296","author":"Arnold","year":"2006","journal-title":"Dev Biol"},{"key":"key20200713100139_b21-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.pneurobio.2013.07.002","article-title":"BMP-Smad 1\/5\/8 signalling in the development of the nervous system","volume":"109","author":"Hegarty","year":"2013","journal-title":"Prog Neurobiol"},{"key":"key20200713100139_b22-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1101\/gad.1202604","article-title":"In vivo convergence of BMP and MAPK signaling pathways: Impact of differential Smad1 phosphorylation on development and homeostasis","volume":"18","author":"Aubin","year":"2004","journal-title":"Genes Dev"},{"key":"key20200713100139_b23-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/1471-213X-8-86","article-title":"An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney","volume":"8","author":"Blank","year":"2008","journal-title":"BMC Dev Biol"},{"key":"key20200713100139_b24-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"21827","DOI":"10.1074\/jbc.M000978200","article-title":"Smad1 and Smad4 are components of the bone morphogenetic protein-4 (BMP-4)-induced transcription complex of the Xvent-2B promoter","volume":"275","author":"Henningfeld","year":"2000","journal-title":"J Biol Chem"},{"key":"key20200713100139_b25-etm-0-0-7530","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1002\/cne.21770","article-title":"Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: Relationship to timing of cell cycle exit","volume":"509","author":"Chalazonitis","year":"2008","journal-title":"J Comp Neurol"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T09:01:43Z","timestamp":1594630903000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,25]]},"references-count":25,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7530","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,25]]}}}