{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T11:39:24Z","timestamp":1703245164843},"reference-count":43,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7559","type":"journal-article","created":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T10:30:34Z","timestamp":1557311434000},"source":"Crossref","is-referenced-by-count":2,"title":["Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue"],"prefix":"10.3892","author":[{"given":"Tezcan","family":"Caliskan","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Namik Kemal University School of Medicine, Tekirdag 59100, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duygu","family":"Yasar Sirin","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Namik Kemal University, Tekirdag 59100, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Numan","family":"Karaarslan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Namik Kemal University School of Medicine, Tekirdag 59100, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Medical Pharmacology, Istanbul Medipol University School of Medicine, Istanbul 34810, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanefi","family":"Ozbek","sequence":"additional","affiliation":[{"name":"Department of Medical Pharmacology, Istanbul Medipol University School of Medicine, Istanbul 34810, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yener","family":"Akyuva","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gaziosmanpasa Taksim Training and Research Hospital, Istanbul 34433, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Necati","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Corlu Reyap Hospital, Istanbul Rumeli University, Tekirdag 59680, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasin","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Orthopedic and Traumatology, Abant Izzet Basal University School of Medicine, Bolu 14000, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Simsek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Namik Kemal University School of Medicine, Tekirdag 59100, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliye","family":"Yildirim Guzelant","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Corlu Reyap Hospital, Istanbul Rumeli University, Tekirdag 59680, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozkan","family":"Ates","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Esencan Hospital, Istanbul Esenyurt University, Istanbul 34570, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,5,8]]},"reference":[{"key":"key20200713100113_b1-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"37","DOI":"10.4103\/ajns.AJNS_307_16","article-title":"Etanercept prevents histopathological damage after spinal cord injury in rats","volume":"13","author":"Hasturk","year":"2018","journal-title":"Asian J Neurosurg"},{"key":"key20200713100113_b2-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/s13018-015-0264-y","article-title":"Are biological agents toxic to human chondrocytes and osteocytes?","volume":"10","author":"Isyar","year":"2015","journal-title":"J Orthop Surg Res"},{"key":"key20200713100113_b3-etm-0-0-7559","first-page":"506","volume":"24","author":"Turkoglu","year":"2014","journal-title":"Turk Neurosurg"},{"key":"key20200713100113_b4-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s11064-014-1506-9","article-title":"Etanercept alleviates early brain injury following experimental subarachnoid hemorrhage and the possible role of tumor necrosis factor-\u03b1 and c-Jun N-terminal kinase pathway","volume":"40","author":"Zhang","year":"2015","journal-title":"Neurochem Res"},{"key":"key20200713100113_b5-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s13195-015-0149-7","article-title":"Central delivery of iodine-125-labeled cetuximab, etanercept and anakinra after perispinal injection in rats: Possible implications for treating Alzheimer's disease","volume":"7","author":"Roerink","year":"2015","journal-title":"Alzheimers Res Ther"},{"key":"key20200713100113_b6-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1007\/s00586-012-2319-7","article-title":"Etanercept treatment enhances clinical and neuroelectrophysiological recovery in partial spinal cord injury","volume":"21","author":"Bayrakli","year":"2012","journal-title":"Eur Spine J"},{"key":"key20200713100113_b7-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"13","DOI":"10.3109\/01480545.2016.1166249","article-title":"Are chondrocytes damaged when rheumatologic inflammation is suppressed?","volume":"40","author":"Guzelant","year":"2017","journal-title":"Drug Chem Toxicol"},{"key":"key20200713100113_b8-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.5114\/aoms.2018.73134","article-title":"Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1\u03b1 and COL2A1 gene expression","volume":"14","author":"Sirin","year":"2018","journal-title":"Arch Med Sci"},{"key":"key20200713100113_b9-etm-0-0-7559","first-page":"1259","article-title":"Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue","volume":"16","author":"Karaarslan","year":"2018","journal-title":"Exp Ther Med"},{"key":"key20200713100113_b10-etm-0-0-7559","first-page":"1647","article-title":"Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue","volume":"16","author":"Karaarslan","year":"2018","journal-title":"Exp Ther Med"},{"key":"key20200713100113_b11-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1177\/1352458512461969","article-title":"Tumefactive demyelinating lesions during etanercept treatment requiring decompressive hemicraniectomy","volume":"19","author":"Cereda","year":"2013","journal-title":"Mult Scler"},{"key":"key20200713100113_b12-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1055\/s-0034-1372435","article-title":"Rapidly fatal internal carotid artery mycotic aneurysm rupture in a rheumatoid patient taking a TNF-\u03b1 inhibitor: Case report and literature review","volume":"76","author":"Bowers","year":"2015","journal-title":"J Neurol Surg A Cent Eur Neurosurg"},{"key":"key20200713100113_b13-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3121\/cmr.2012.1049","article-title":"Brain abscesses complicating acute pneumococcal meningitis during etanercept therapy","volume":"10","author":"Kasirye","year":"2012","journal-title":"Clin Med Res"},{"key":"key20200713100113_b14-etm-0-0-7559","first-page":"43","article-title":"Are specific gene expressions of extracellular matrix and nucleus pulposus affected by primary cell cultures prepared from intact or degenerative intervertebral disc tissues?","volume":"29","author":"Karaarslan","year":"2019","journal-title":"Turk Neurosurg"},{"key":"key20200713100113_b15-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1097\/BRS.0000000000000929","article-title":"Evaluation of 12 novel molecular markers for degenerated nucleus pulposus in a Chinese population","volume":"40","author":"Chen","year":"2015","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b16-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1097\/00007632-199807150-00021","article-title":"Matrix metalloproteinases: The clue to intervertebral disc degeneration?","volume":"23","author":"Goupille","year":"1998","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b17-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1097\/00007632-199705150-00003","article-title":"Toward a biochemical understanding of human intervertebral disc degeneration and herniation. Contributions of nitric oxide, interleukins, prostaglandin E2 and matrix metalloproteinases","volume":"22","author":"Kang","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b18-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1097\/00007632-199602010-00003","article-title":"Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6 and prostaglandin E2","volume":"21","author":"Kang","year":"1996","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b19-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"2877","DOI":"10.1097\/00007632-199712150-00010","article-title":"Matrix metalloproteinases in the human intervertebral disc: Role in disc degeneration and scoliosis","volume":"22","author":"Crean","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b20-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1522","DOI":"10.1097\/00007632-200107150-00004","article-title":"Influence of macrophage infiltration of herniated disc tissue on the production of matrix metalloproteinases leading to disc resorption","volume":"26","author":"Doita","year":"2001","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b21-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1097\/00007632-199804150-00005","article-title":"The involvement of matrix metalloproteinases and inflammation in lumbar disc herniation","volume":"23","author":"Matsui","year":"1998","journal-title":"Spine"},{"key":"key20200713100113_b22-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1002\/1529-0131(200006)43:6<1315::AID-ANR14>3.0.CO;2-#","article-title":"Stimulation of hyaluronan metabolism by interleukin-1alpha in human articular cartilage","volume":"43","author":"Nishida","year":"2000","journal-title":"Arthritis Rheum"},{"key":"key20200713100113_b23-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s003930050163","article-title":"The role of cytokines and growth factors in cartilage destruction in osteoarthritis and rheumatoid arthritis","volume":"58","author":"van den Berg","year":"1999","journal-title":"Z Rheumatol"},{"key":"key20200713100113_b24-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1097\/00007632-199907150-00002","article-title":"Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc","volume":"24","author":"Takae","year":"1999","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b25-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/00007632-200001010-00005","article-title":"Sensitivity of anulus fibrosus cells to interleukin 1 beta. Comparison with articular chondrocytes","volume":"25","author":"Rannou","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"key":"key20200713100113_b26-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1002\/art.21814","article-title":"Guillain-Barr\u00e9 and Miller Fisher syndromes occurring with tumor necrosis factor alpha antagonist therapy","volume":"54","author":"Shin","year":"2006","journal-title":"Arthritis Rheum"},{"key":"key20200713100113_b27-etm-0-0-7559","article-title":"Medication Guide","author":"Highlights of Prescribing Information. In"},{"key":"key20200713100113_b28-etm-0-0-7559","first-page":"180","article-title":"Delivering growth factors through a polymeric scaffold to cell cultures containing both nucleus pulposus and annulus fibrosus","volume":"29","author":"Akyuva","year":"2019","journal-title":"Turk Neurosurg"},{"key":"key20200713100113_b29-etm-0-0-7559","first-page":"100","article-title":"Which pharmacological agents may be used to establish healthy, proliferating human primer nucleus pulposus\/annulus fibrosus cell cultures? Systematic evaluation of our experience in the light of literature","volume":"6","author":"Karaarslan","year":"2018","journal-title":"Merit Res J Med Med Sci"},{"key":"key20200713100113_b30-etm-0-0-7559","first-page":"477","article-title":"How scaffolds, which are polymeric drug delivery systems allowing controlled release, can be tested in human primary nucleus pulposus and annulus fibrosus cell cultures?","volume":"5","author":"Akyuva","year":"2017","journal-title":"Merit Res J Med Med Sci"},{"key":"key20200713100113_b31-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.jim.2017.03.007","article-title":"Establishment of the first WHO international standard for etanercept, a TNF receptor II Fc fusion protein: Report of an international collaborative study","volume":"447","author":"Wadhwa","year":"2017","journal-title":"J Immunol Methods"},{"key":"key20200713100113_b32-etm-0-0-7559","first-page":"e33453","article-title":"Cytotoxic effects of some common organic solvents on MCF-7, RAW-264.7 and human umbilical vein endothelial cells","volume":"4","author":"Jamalzadeh","year":"2016","journal-title":"Avicenna J Med Biochem"},{"key":"key20200713100113_b33-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.3748\/wjg.15.1168","article-title":"In vitro and in vivo models of acute alcohol exposure","volume":"15","author":"Dolganiuc","year":"2009","journal-title":"World J Gastroenterol"},{"key":"key20200713100113_b34-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20200713100113_b35-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"898","DOI":"10.4103\/aer.AER_160_17","article-title":"Comparison of the intravenous and epidural administration of tumor necrosis factor-alpha antagonists in an experimental rat pain model","volume":"11","author":"Beyaz","year":"2017","journal-title":"Anesth Essays Res"},{"key":"key20200713100113_b36-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1007\/s00586-011-1854-y","article-title":"Etanercept attenuates pain-related behavior following compression of the dorsal root ganglion in the rat","volume":"20","author":"Watanabe","year":"2011","journal-title":"Eur Spine J"},{"key":"key20200713100113_b37-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1007\/s10735-015-9640-5","article-title":"IL-17A enhances ADAMTS-7 expression through regulation of TNF-\u03b1 in human nucleus pulposus cells","volume":"46","author":"Wang","year":"2015","journal-title":"J Mol Histol"},{"key":"key20200713100113_b38-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3928\/01477447-20160926-03","article-title":"Effects of tumor necrosis factor inhibitor on stress-shielded tendons","volume":"40","author":"Chen","year":"2017","journal-title":"Orthopedics"},{"key":"key20200713100113_b39-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"R181","DOI":"10.1186\/ar760","article-title":"Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or Etanercept","volume":"5","author":"Crnkic","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"key20200713100113_b40-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"20141191","DOI":"10.1098\/rsif.2015.0429","article-title":"Inflammation in intervertebral disc degeneration and regeneration","volume":"12","author":"Molinos","year":"2015","journal-title":"J R Soc Interface"},{"key":"key20200713100113_b41-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/nyas.13551","article-title":"Inflammatory biomarkers of low back pain and disc degeneration: a review","volume":"1410","author":"Khan","year":"2017","journal-title":"Ann N Y Acad Sci"},{"key":"key20200713100113_b42-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"4112","DOI":"10.1038\/s41598-017-04384-3","article-title":"IL-1\u03b2 increases asporin expression via the NF-\u03baB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration","volume":"7","author":"Wang","year":"2017","journal-title":"Sci Rep"},{"key":"key20200713100113_b43-etm-0-0-7559","doi-asserted-by":"publisher","first-page":"R215","DOI":"10.1186\/ar3548","article-title":"Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: Implications for the mechanisms of intervertebral disc degeneration","volume":"13","author":"Erwin","year":"2011","journal-title":"Arthritis Res Ther"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T09:01:28Z","timestamp":1594630888000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,8]]},"references-count":43,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7559","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,8]]}}}