{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:20:01Z","timestamp":1759335601904},"reference-count":42,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7608","type":"journal-article","created":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T08:49:26Z","timestamp":1558687766000},"source":"Crossref","is-referenced-by-count":1,"title":["Soluble Tei2 fusion protein inhibits retinopathy of prematurity occurrence via regulation of the Ang\/Tie2 pathway"],"prefix":"10.3892","author":[{"given":"Weijing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weihua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuiying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunfang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangling","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"key20200713100248_b1-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/0002-9394(74)90010-5","article-title":"Blindness caused by diabetic retinopathy","volume":"78","author":"Kahn","year":"1974","journal-title":"Am J Ophthalmol"},{"key":"key20200713100248_b2-etm-0-0-7608","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1542\/peds.86.3.405","article-title":"Retinopathy of prematurity-induced blindness: Birth weight-specific survival and the new epidemic","volume":"86","author":"Gibson","year":"1990","journal-title":"Pediatrics"},{"key":"key20200713100248_b3-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1056\/NEJMc1301021","article-title":"Mechanisms and management of retinopathy of prematurity","volume":"368","author":"Jasani","year":"2013","journal-title":"N Engl J Med"},{"key":"key20200713100248_b4-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1056\/NEJMc1301021","article-title":"Mechanisms and management of retinopathy of prematurity","volume":"368","author":"Rao","year":"2013","journal-title":"N Engl J Med"},{"key":"key20200713100248_b5-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"2515","DOI":"10.1056\/NEJMra1208129","article-title":"Mechanisms and management of retinopathy of prematurity","volume":"367","author":"Hartnett","year":"2012","journal-title":"N Engl J Med"},{"key":"key20200713100248_b6-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1038\/nprot.2009.187","article-title":"Quantification of oxygen-induced retinopathy in the mouse: A model of vessel loss, vessel regrowth and pathological angiogenesis","volume":"4","author":"Connor","year":"2009","journal-title":"Nat Protoc"},{"key":"key20200713100248_b7-etm-0-0-7608","first-page":"103","article-title":"Quantification of oxygen-induced retinopathy in the mouse","volume":"22","author":"Liu","year":"2006","journal-title":"Yan Ke Xue Bao"},{"key":"key20200713100248_b8-etm-0-0-7608","first-page":"98","article-title":"A modified mouse model of oxygen-induced retinopathy","volume":"22","author":"Ding","year":"2006","journal-title":"Yan Ke Xue Bao"},{"key":"key20200713100248_b9-etm-0-0-7608","first-page":"101","article-title":"Oxygen-induced retinopathy in the mouse","volume":"35","author":"Smith","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key20200713100248_b10-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.ajo.2011.07.005","article-title":"Serum concentrations of bevacizumab (avastin) and vascular endothelial growth factor in infants with retinopathy of prematurity","volume":"153","author":"Sato","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"key20200713100248_b11-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/j.1651-2227.2012.02757.x","article-title":"Is Avastin the right choice of treatment for retinopathy of prematurity?","volume":"101","author":"K\u00e4ll","year":"2012","journal-title":"Acta Paediatr"},{"key":"key20200713100248_b12-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.jaapos.2011.11.002","article-title":"Bevacizumab (Avastin) for retinopathy of prematurity: Wrong dose, wrong drug, or both?","volume":"16","author":"Avery","year":"2012","journal-title":"J AAPOS"},{"key":"key20200713100248_b13-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1863","DOI":"10.1097\/IAE.0b013e318219de8b","article-title":"Treatment of macular edema because of occlusive vasculitis with bevacizumab (avastin): Efficacy of three consecutive monthly injections","volume":"31","author":"Nuti","year":"2011","journal-title":"Retina"},{"key":"key20200713100248_b14-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1097\/IAE.0b013e3181619bee","article-title":"Comparison of two doses of intravitreal bevacizumab (Avastin) for treatment of macular edema secondary to branch retinal vein occlusion: Results from the Pan-American Collaborative Retina Study Group at 6 months of follow-up","volume":"28","author":"Wu","year":"2008","journal-title":"Retina"},{"key":"key20200713100248_b15-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1097\/IAE.0b013e318176de48","article-title":"Long-term effect of intravitreal bevacizumab (avastin) in patients with chronic diffuse diabetic macular edema","volume":"28","author":"Kook","year":"2008","journal-title":"Retina"},{"key":"key20200713100248_b16-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.ajo.2012.06.010","article-title":"An updated study of the use of bevacizumab in the treatment of patients with prethreshold retinopathy of prematurity in taiwan","volume":"155","author":"Wu","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"key20200713100248_b17-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.tranon.2014.02.003","article-title":"The role of angiopoietins as potential therapeutic targets in renal cell carcinoma","volume":"7","author":"Wang","year":"2014","journal-title":"Transl Oncol"},{"key":"key20200713100248_b18-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"e39796","DOI":"10.1371\/journal.pone.0039796","article-title":"Autocrine role of angiopoietins during megakaryocytic differentiation","volume":"7","author":"Saulle","year":"2012","journal-title":"PLoS One"},{"key":"key20200713100248_b19-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10456-009-9147-3","article-title":"The role of the Angiopoietins in vascular morphogenesis","volume":"12","author":"Thomas","year":"2009","journal-title":"Angiogenesis"},{"key":"key20200713100248_b20-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"H2547","DOI":"10.1152\/ajpheart.01250.2007","article-title":"Critical role of angiopoietins\/Tie-2 in hyperglycemic exacerbation of myocardial infarction and impaired angiogenesis","volume":"294","author":"Tuo","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key20200713100248_b21-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1182\/blood-2003-12-4219","article-title":"The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors","volume":"104","author":"Hildbrand","year":"2004","journal-title":"Blood"},{"key":"key20200713100248_b22-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/08977190310001643218","article-title":"The role of the angiopoietins in tumour angiogenesis","volume":"22","author":"Plank","year":"2004","journal-title":"Growth Factors"},{"key":"key20200713100248_b23-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s00441-003-0749-6","article-title":"Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis","volume":"314","author":"Thurston","year":"2003","journal-title":"Cell Tissue Res"},{"key":"key20200713100248_b24-etm-0-0-7608","first-page":"31","article-title":"Angiopoietins and their role in colon cancer angiogenesis","volume":"16","author":"Ellis","year":"2002","journal-title":"Oncology (Williston Park)"},{"key":"key20200713100248_b25-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.ophtha.2013.08.038","article-title":"Long-term outcomes in patients with retinal vein occlusion treated with ranibizumab: The RETAIN study","volume":"121","author":"Campochiaro","year":"2014","journal-title":"Ophthalmology"},{"key":"key20200713100248_b26-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1046\/j.1365-2362.2003.01173.x","article-title":"Measurement of the soluble angiopoietin receptor tie-2 in patients with coronary artery disease: Development and application of an immunoassay","volume":"33","author":"Chung","year":"2003","journal-title":"Eur J Clin Invest"},{"key":"key20200713100248_b27-etm-0-0-7608","first-page":"1","article-title":"Soluble angiopoietin receptor Tie-2 in patients with acute myocardial infarction and its effects on angiogenesis","volume":"33","author":"Wang","year":"2005","journal-title":"Clin Hemorheol Microcirc"},{"key":"key20200713100248_b28-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.bbrc.2005.04.108","article-title":"Systemic soluble Tie2 expression inhibits and regresses corneal neovascularization","volume":"332","author":"Singh","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"key20200713100248_b29-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1167\/iovs.02-0276","article-title":"Potential role of the angiopoietin\/tie2 system in ischemia-induced retinal neovascularization","volume":"44","author":"Takagi","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key20200713100248_b30-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1089\/104303401750270968","article-title":"Systemically expressed soluble Tie2 inhibits intraocular neovascularization","volume":"12","author":"Hangai","year":"2001","journal-title":"Hum Gene Ther"},{"key":"key20200713100248_b31-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"e203559","DOI":"10.1371\/journal.pone.0203559","article-title":"Impact of repeated anesthesia with ketamine and xylazine on the well-being of C57BL\/6JRj mice","volume":"13","author":"Hohlbaum","year":"2018","journal-title":"PLoS One"},{"key":"key20200713100248_b32-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.neuroimage.2018.04.062","article-title":"Mouse fMRI under ketamine and xylazine anesthesia: Robust contralateral somatosensory cortex activation in response to forepaw stimulation","volume":"177","author":"Shim","year":"2018","journal-title":"Neuroimage"},{"key":"key20200713100248_b33-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1097\/NEN.0b013e3181ffc420","article-title":"Development of postinfection epilepsy after Theiler's virus infection of C57BL\/6 mice","volume":"69","author":"Stewart","year":"2010","journal-title":"J Neuropathol Exp Neurol"},{"key":"key20200713100248_b34-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"438","DOI":"10.3109\/02713683.2011.647227","article-title":"Evaluation of changes in choroidal neovascularization secondary to age-related macular degeneration after anti-VEGF therapy using spectral domain optical coherence tomography","volume":"37","author":"You","year":"2012","journal-title":"Curr Eye Res"},{"key":"key20200713100248_b35-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00417-012-2022-8","article-title":"Long-term effect of intravitreal injection of anti-VEGF agent for visual acuity and chorioretinal atrophy progression in myopic choroidal neovascularization","volume":"251","author":"Oishi","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"key20200713100248_b36-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1038\/eye.2012.75","article-title":"Spectral-domain OCT in anti-VEGF treatment of myopic choroidal neovascularization","volume":"26","author":"Introini","year":"2012","journal-title":"Eye (Lond)"},{"key":"key20200713100248_b37-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1167\/iovs.14-13897","article-title":"Angiopoietin-1 suppresses choroidal neovascularization and vascular leakage","volume":"55","author":"Lee","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key20200713100248_b38-etm-0-0-7608","first-page":"584","article-title":"Potential protective effect of angiopoietin-1 on the leakage of rat choroidal neovascularization","volume":"34","author":"Wang","year":"2013","journal-title":"Saudi Med J"},{"key":"key20200713100248_b39-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1159\/000218174","article-title":"Decreased hypoxia-induced neovascularization in angiopoietin-2 heterozygous knockout mouse through reduced MMP activity","volume":"23","author":"Feng","year":"2009","journal-title":"Cell Physiol Biochem"},{"key":"key20200713100248_b40-etm-0-0-7608","first-page":"223","article-title":"Postnatal weight gain in preterm infants with severe bronchopulmonary dysplasia","volume":"31","author":"Natarajan","year":"2014","journal-title":"Am J Perinatol"},{"key":"key20200713100248_b41-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1136\/thx.2006.064642","article-title":"Associations between postnatal weight gain, change in postnatal pulmonary function, formula feeding and early asthma","volume":"63","author":"Turner","year":"2008","journal-title":"Thorax"},{"key":"key20200713100248_b42-etm-0-0-7608","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1001\/jamapediatrics.2017.4838","article-title":"Comparing alternative ranibizumab dosages for safety and efficacy in retinopathy of prematurity: A randomized clinical trial","volume":"172","author":"Stahl","year":"2018","journal-title":"Jama Pediatr"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T15:35:26Z","timestamp":1663515326000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,24]]},"references-count":42,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7608","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,24]]}}}