{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T07:04:14Z","timestamp":1770966254194,"version":"3.50.1"},"reference-count":63,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2019.7784","type":"journal-article","created":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T10:35:26Z","timestamp":1563359726000},"source":"Crossref","is-referenced-by-count":6,"title":["Eldecalcitol effects on osteoblastic differentiation and function in the presence or absence of osteoclastic bone resorption"],"prefix":"10.3892","author":[{"given":"Jie","family":"Bu","sequence":"first","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Jinan Stomatological Hospital, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoka","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology of Hard Tissue, Graduate School of Dental Medicine, Hokkaido University, Sapporo 060\u20118586, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongrui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuxia","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Oral Maxillofacial Surgery, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minqi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,7,17]]},"reference":[{"key":"key20200713100721_b1-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1196\/annals.1365.035","article-title":"Bone remodeling","volume":"1092","author":"Hadjidakis","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"key20200713100721_b2-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.abb.2008.03.027","article-title":"Osteoclast-osteoblast communication","volume":"473","author":"Matsuo","year":"2008","journal-title":"Arch Biochem Biophys"},{"key":"key20200713100721_b3-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"196","DOI":"10.2174\/187152812800392670","article-title":"Osteoblast and osteoclast crosstalks: From OAF to Ephrin","volume":"11","author":"Tamma","year":"2012","journal-title":"Inflamm Allergy Drug Targets"},{"key":"key20200713100721_b4-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1002\/jcb.10623","article-title":"In vivo administration of 1,25-dihydroxyvitamin D3 suppresses the expression of RANKL mRNA in bone of thyroparathyroidectomized rats constantly infused with PTH","volume":"90","author":"Ueno","year":"2003","journal-title":"J Cell Biochem"},{"key":"key20200713100721_b5-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1038\/bonekey.2013.227","article-title":"Vitamin D endocrine system and osteoblasts","volume":"3","author":"van Driel","year":"2014","journal-title":"Bonekey Rep"},{"key":"key20200713100721_b6-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1046\/j.1365-2133.1996.d01-904.x","article-title":"Efficacy and safety of topical calcitriol (1,25-dihydroxyvitamin d3) for the treatment of psoriasis","volume":"134","author":"P\u00e8rez","year":"1996","journal-title":"Br J Dermatol"},{"key":"key20200713100721_b7-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1146\/annurev.pharmtox.41.1.421","article-title":"Cancer chemoprevention using natural vitamin D and synthetic analogs","volume":"41","author":"Guyton","year":"2001","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"key20200713100721_b8-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s007740200008","article-title":"Active vitamin D and its analogs as drugs for the treatment of osteoporosis: Advantages and problems","volume":"20","author":"Nishii","year":"2002","journal-title":"J Bone Miner Metab"},{"key":"key20200713100721_b9-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0039-128X(00)00227-0","article-title":"History of the development of new vitamin D analogs: Studies on 22-oxacalcitriol (OCT) and 2beta- (3-hydroxypropoxy)calcitriol (ED-71)","volume":"66","author":"Nishii","year":"2001","journal-title":"Steroids"},{"key":"key20200713100721_b10-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1002\/jcb.10328","article-title":"Rationale for active vitamin D and analogs in the treatment of osteoporosis","volume":"88","author":"Nishii","year":"2003","journal-title":"J Cell Biochem"},{"key":"key20200713100721_b11-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"2038","DOI":"10.1021\/acs.bioconjchem.5b00433","article-title":"Development of novel bioluminescent sensor to detect and discriminate between vitamin D receptor agonists and antagonists in living cells","volume":"26","author":"Mano","year":"2015","journal-title":"Bioconjug Chem"},{"key":"key20200713100721_b12-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"5031","DOI":"10.1210\/jc.2004-2552","article-title":"A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: A randomized, double-blind, placebo-controlled clinical trial","volume":"90","author":"Matsumoto","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"key20200713100721_b13-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.jsbmb.2010.03.035","article-title":"Comparison of the effects of eldecalcitol and alfacalcidol on bone and calcium metabolism","volume":"121","author":"Matsumoto","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key20200713100721_b14-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jsbmb.2010.03.041","article-title":"Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1alpha,25- dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71]","volume":"121","author":"Hatakeyama","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key20200713100721_b15-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1016\/S8756-3282(02)00682-8","article-title":"ED-71, a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis","volume":"30","author":"Uchiyama","year":"2002","journal-title":"Bone"},{"key":"key20200713100721_b16-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/nm.1979","article-title":"TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation","volume":"15","author":"Tang","year":"2009","journal-title":"Nat Med"},{"key":"key20200713100721_b17-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1002\/jbmr.2586","article-title":"Osteoclast TGF-\u03b2 receptor signaling induces Wnt1 secretion and couples bone resorption to bone formation","volume":"31","author":"Weivoda","year":"2016","journal-title":"J Bone Miner Res"},{"key":"key20200713100721_b18-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1038\/nm.2793","article-title":"Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells","volume":"18","author":"Xian","year":"2012","journal-title":"Nat Med"},{"key":"key20200713100721_b19-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1002\/path.4661","article-title":"Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP\/Endo180","volume":"238","author":"Engelholm","year":"2016","journal-title":"J Pathol"},{"key":"key20200713100721_b20-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"2584","DOI":"10.3390\/nu6072584","article-title":"Effects of \u03c93- and \u03c96-polyunsaturated fatty acids on RANKL-induced osteoclast differentiation of RAW264.7 cells: A comparative in vitro study","volume":"6","author":"Boeyens","year":"2014","journal-title":"Nutrients"},{"key":"key20200713100721_b21-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/j.bone.2010.08.001","article-title":"AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts","volume":"47","author":"Lee","year":"2010","journal-title":"Bone"},{"key":"key20200713100721_b22-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"810563","DOI":"10.1155\/2012\/810563","article-title":"Fisetin inhibits osteoclast differentiation via downregulation of p38 and c-Fos-NFATc1 signaling pathways","volume":"2012","author":"Choi","year":"2012","journal-title":"Evid Based Complement Alternat Med"},{"key":"key20200713100721_b23-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20200713100721_b24-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"2044","DOI":"10.1182\/blood-2004-03-1196","article-title":"TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF","volume":"104","author":"Zauli","year":"2004","journal-title":"Blood"},{"key":"key20200713100721_b25-etm-0-0-7784","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/ptr.2984","article-title":"Stimulatory effect of undecylenic acid on mouse osteoblast differentiation","volume":"24","author":"Kim","year":"2010","journal-title":"Phytother Res"},{"key":"key20200713100721_b26-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1359\/jbmr.2002.17.2.257","article-title":"Platelet-derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor","volume":"17","author":"Kubota","year":"2010","journal-title":"J Bone Miner Res"},{"key":"key20200713100721_b27-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"325","DOI":"10.2174\/1568010054022015","article-title":"Osteoblasts and osteoclasts in bone remodeling and inflammation","volume":"4","author":"Tanaka","year":"2005","journal-title":"Curr Drug Targets Inflamm Allergy"},{"key":"key20200713100721_b28-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1248\/bpb.24.628","article-title":"Effects of various antihypertensive drugs on the function of osteoblast","volume":"24","author":"Nishiya","year":"2001","journal-title":"Biol Pharm Bull"},{"key":"key20200713100721_b29-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"123","DOI":"10.2220\/biomedres.38.123","article-title":"Histochemical assessment for osteoblastic activity coupled with dysfunctional osteoclasts in c-src deficient mice","volume":"38","author":"Toray","year":"2017","journal-title":"Biomed Res"},{"key":"key20200713100721_b30-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/s00441-009-0832-8","article-title":"Regulation of bone development and extracellular matrix protein genes by RUNX2","volume":"339","author":"Komori","year":"2010","journal-title":"Cell Tissue Res"},{"key":"key20200713100721_b31-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.patbio.2008.06.004","article-title":"In vitro osteogenesis assays: Influence of the primary cell source on alkaline phosphatase activity and mineralization","volume":"57","author":"Hoemann","year":"2009","journal-title":"Pathol Biol (Paris)"},{"key":"key20200713100721_b32-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/s41413-018-0019-6","article-title":"Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts","volume":"6","author":"Han","year":"2018","journal-title":"Bone Res"},{"key":"key20200713100721_b33-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1210\/endo-118-3-940","article-title":"Effects of 1,25-dihydroxyvitamin D3 on osteoblastic MC3T3-E1 cells","volume":"118","author":"Kurihara","year":"1986","journal-title":"Endocrinology"},{"key":"key20200713100721_b34-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0960-0760(95)00218-9","article-title":"Differential effects of 1,25-dihydroxyvitamin D3-analogs on osteoblast-like cells and on in vitro bone resorption","volume":"55","author":"van den Bemd","year":"1995","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key20200713100721_b35-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1093\/oxfordjournals.jbchem.a134456","article-title":"1 alpha, 25-Dihydroxyvitamin D3 and analogues of vitamin D3 induce alkaline phosphatase activity in osteoblastic cells derived from newborn mouse calvaria","volume":"94","author":"Haneji","year":"1983","journal-title":"J Biochem"},{"key":"key20200713100721_b36-etm-0-0-7784","doi-asserted-by":"crossref","first-page":"3362","DOI":"10.1016\/S0021-9258(18)34781-1","article-title":"The effect of 1,25(OH)2D3 on alkaline phosphatase in osteoblastic osteosarcoma cells","volume":"257","author":"Majeska","year":"1982","journal-title":"J Biol Chem"},{"key":"key20200713100721_b37-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"582S","DOI":"10.1093\/ajcn\/88.2.582S","article-title":"Pharmacokinetics of vitamin D toxicity","volume":"88","author":"Jones","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"key20200713100721_b38-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/jcp.1041470306","article-title":"Relative binding and biochemical effects of heterodimeric and homodimeric isoforms of platelet-derived growth factor in osteoblast-enriched cultures from fetal rat bone","volume":"147","author":"Centrella","year":"1991","journal-title":"J Cell Physiol"},{"key":"key20200713100721_b39-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"C1709","DOI":"10.1152\/ajpcell.1997.272.5.C1709","article-title":"Temporal expression of PDGF receptors and PDGF regulatory effects on osteoblastic cells in mineralizing cultures","volume":"272","author":"Yu","year":"1997","journal-title":"Am J Physiol"},{"key":"key20200713100721_b40-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"5840","DOI":"10.1038\/sj.emboj.7601430","article-title":"Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling","volume":"25","author":"Ryu","year":"2006","journal-title":"EMBO J"},{"key":"key20200713100721_b41-etm-0-0-7784","first-page":"32","article-title":"Effect of the bone resorption supernatant from RAW264.7 osteoclast on the osteogenic activity of mouse MC3T3-E1 cell","volume":"47","author":"Chen","year":"2012","journal-title":"Zhonghua Kou Qiang Yi Xue Za Zhi"},{"key":"key20200713100721_b42-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"3204","DOI":"10.1073\/pnas.78.5.3204","article-title":"Parathyroid hormone stimulates bone formation and resorption in organ culture: Evidence for a coupling mechanism","volume":"78","author":"Howard","year":"1981","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713100721_b43-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.molmed.2004.12.004","article-title":"Osteoclast-derived activity in the coupling of bone formation to resorption","volume":"11","author":"Martin","year":"2005","journal-title":"Trends Mol Med"},{"key":"key20200713100721_b44-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1359\/jbmr.070109","article-title":"Are nonresorbing osteoclasts sources of bone anabolic activity?","volume":"22","author":"Karsdal","year":"2007","journal-title":"J Bone Miner Res"},{"key":"key20200713100721_b45-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.micron.2005.06.008","article-title":"Reduced osteoblastic population and defective mineralization in osteopetrotic (op\/op) mice","volume":"36","author":"Sakagami","year":"2005","journal-title":"Micron"},{"key":"key20200713100721_b46-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1126\/science.7939685","article-title":"c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling","volume":"266","author":"Grigoriadis","year":"1994","journal-title":"Science"},{"key":"key20200713100721_b47-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/0092-8674(91)90499-O","article-title":"Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice","volume":"64","author":"Soriano","year":"1991","journal-title":"Cell"},{"key":"key20200713100721_b48-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/8756-3282(95)00456-4","article-title":"Topographically induced bone formation in vitro: Implications for bone implants and bone grafts","volume":"18","author":"Gray","year":"1996","journal-title":"Bone"},{"key":"key20200713100721_b49-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"S72","DOI":"10.1007\/BF02152357","article-title":"Anabolic effect of parathyroid hormone on bone in the rat","author":"Kalu","year":"1970","journal-title":"Calcif Tissue Res"},{"key":"key20200713100721_b50-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1359\/jbmr.060714","article-title":"Vitamin D action and regulation of bone remodeling: Suppression of osteoclastogenesis by the mature osteoblast","volume":"21","author":"Baldock","year":"2006","journal-title":"J Bone Miner Res"},{"key":"key20200713100721_b51-etm-0-0-7784","first-page":"871","article-title":"Calcium homeostasis and normal bone remodeling","volume":"167","author":"Schwarz","year":"2005","journal-title":"Ugeskr Laeger"},{"key":"key20200713100721_b52-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"e3537","DOI":"10.1371\/journal.pone.0003537","article-title":"Osteoclasts control osteoblast chemotaxis via PDGF-BB\/PDGF receptor beta signaling","volume":"3","author":"Sanchez-Fernandez","year":"2008","journal-title":"PLoS One"},{"key":"key20200713100721_b53-etm-0-0-7784","first-page":"666","article-title":"Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation","volume":"123","author":"Lotinun","year":"2013","journal-title":"J Clin Invest"},{"key":"key20200713100721_b54-etm-0-0-7784","first-page":"1313","article-title":"Eldecalcitol for the treatment of osteoporosis","volume":"8","author":"Noguchi","year":"2013","journal-title":"Clin Interv Aging"},{"key":"key20200713100721_b55-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.abb.2011.11.011","article-title":"Bone effects of vitamin D-Discrepancies between in vivo and in vitro studies","volume":"523","author":"Suda","year":"2012","journal-title":"Arch Biochem Biophys"},{"key":"key20200713100721_b56-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.bone.2007.04.174","article-title":"Effects of continuous activation of vitamin D and Wnt response pathways on osteoblastic proliferation and differentiation","volume":"41","author":"Shi","year":"2007","journal-title":"Bone"},{"key":"key20200713100721_b57-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.archoralbio.2011.10.005","article-title":"1\u03b1,25-Dihydroxyvitamin D3 inhibits osteoblastic differentiation of mouse periodontal fibroblasts","volume":"57","author":"Chen","year":"2012","journal-title":"Arch Oral Biol"},{"key":"key20200713100721_b58-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.jsbmb.2004.03.021","article-title":"Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition","volume":"89","author":"Tanaka","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key20200713100721_b59-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1210\/en.2012-1542","article-title":"Vitamin D receptor in osteoblasts is a negative regulator of bone mass control","volume":"154","author":"Yamamoto","year":"2013","journal-title":"Endocrinology"},{"key":"key20200713100721_b60-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1002\/jbmr.3096","article-title":"VDR in osteoblast-lineage cells primarily mediates vitamin D treatment-induced increase in bone mass by suppressing bone resorption","volume":"32","author":"Nakamichi","year":"2017","journal-title":"J Bone Miner Res"},{"key":"key20200713100721_b61-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"4982","DOI":"10.1210\/endo.140.11.7110","article-title":"Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses","volume":"140","author":"Amling","year":"1999","journal-title":"Endocrinology"},{"key":"key20200713100721_b62-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.jsbmb.2012.09.019","article-title":"The delicate balance between vitamin D, calcium and bone homeostasis: Lessons learned from intestinal- and osteocyte-specific VDR null mice","volume":"136","author":"Lieben","year":"2013","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key20200713100721_b63-etm-0-0-7784","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.4049\/jimmunol.169.5.2374","article-title":"1,25(OH)2 vitamin D3-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1 alpha and receptor activator of NF-kappa B ligand production in osteoblasts","volume":"169","author":"Lee","year":"2002","journal-title":"J Immunol"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T03:18:14Z","timestamp":1721531894000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2019.7784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,17]]},"references-count":63,"URL":"https:\/\/doi.org\/10.3892\/etm.2019.7784","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,17]]}}}