{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:49:04Z","timestamp":1782863344674,"version":"3.54.5"},"reference-count":19,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2021.10768","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T11:50:22Z","timestamp":1632138622000},"source":"Crossref","is-referenced-by-count":7,"title":["Anthropometric and metabolic profile of children with gene polymorphisms for primary lactose intolerance"],"prefix":"10.3892","volume":"22","author":[{"given":"Corina","family":"Pienar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, 2nd Pediatrics Clinic, \u02bbVictor Babes\u2019 University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liviu","family":"Pop","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, 2nd Pediatrics Clinic, \u02bbVictor Babes\u2019 University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilena","family":"L\u0103z\u0103rescu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care, The Necker\u2011Enfants Malades Hospital, University of Paris Descartes, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radmila","family":"Cost\u0103chescu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, 2nd Pediatrics Clinic, \u02bbVictor Babes\u2019 University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"\u0218ecl\u0103man","sequence":"additional","affiliation":[{"name":"Biochemistry Department, \u02bbVictor Babes\u2019 University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2021,9,20]]},"reference":[{"key":"key20211014132752_b1-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"792","DOI":"10.7326\/0003-4819-152-12-201006150-00248","article-title":"National institutes of health consensus development conference: Lactose intolerance and health","volume":"152","author":"Suchy","year":"2010","journal-title":"Ann Intern Med"},{"key":"key20211014132752_b2-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2147\/CEG.S32368","article-title":"Lactose intolerance: Diagnosis, genetic and clinical factors","volume":"5","author":"Mattar","year":"2012","journal-title":"Clin Exp Gastroenterol"},{"key":"key20211014132752_b3-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/s0014-5793(98)01076-x","article-title":"Intestinal lactase-phlorizin hydrolase (LPH): The two catalytic sites; the role of the pancreas in pro-LPH maturation","volume":"435","author":"Zecca","year":"1998","journal-title":"FEBS Lett"},{"key":"key20211014132752_b4-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1080\/07853890903121033","article-title":"Molecular genetics of human lactase deficiencies","volume":"41","author":"J\u00e4rvel\u00e4","year":"2009","journal-title":"Ann Med"},{"key":"key20211014132752_b5-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1111\/j.1365-2036.2007.03557.x","article-title":"Review article: Lactose intolerance in clinical practice-myths and realities","volume":"27","author":"Lomer","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"key20211014132752_b6-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1002\/iub.1227","article-title":"How long have adult humans been consuming milk?","volume":"65","author":"Gerbault","year":"2013","journal-title":"IUBMB Life"},{"key":"key20211014132752_b7-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1590\/1678-4685-GMB-2016-0071","article-title":"Frequency of adult type-associated lactase persistence LCT-13910C\/T genotypes in the Czech\/Slav and Czech Roma\/Gypsy populations","volume":"40","author":"Hub\u00e1cek","year":"2017","journal-title":"Genet Mol Biol"},{"key":"key20211014132752_b8-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"S31","DOI":"10.6133\/apjcn.2015.24.s1.06","article-title":"Lactose intolerance in Indonesian children","volume":"24 (Suppl 1)","author":"Hegar","year":"2015","journal-title":"Asia Pac J Clin Nutr"},{"key":"key20211014132752_b9-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1542\/peds.2006-1721","article-title":"Lactose intolerance in infants, children, and adolescents","volume":"118","author":"Heyman","year":"2006","journal-title":"Pediatrics"},{"key":"key20211014132752_b10-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1093\/hmg\/ddp561","article-title":"European lactase persistence genotype shows evidence of association with increase in body mass index","volume":"19","author":"Kettunen","year":"2010","journal-title":"Hum Mol Genet"},{"key":"key20211014132752_b11-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/j.metabol.2013.04.006","article-title":"The lactase persistence genotype is associated with body mass index and dairy consumption in the D.E.S.I.R. study","volume":"62","author":"Lamri","year":"2013","journal-title":"Metab Clin Exp"},{"key":"key20211014132752_b12-ETM-0-0-10768","author":"Almon"},{"key":"key20211014132752_b13-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1111\/apt.12006","article-title":"Is the subjective perception of lactose intolerance influenced by the psychological profile?","volume":"36","author":"Tomba","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"key20211014132752_b14-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1159\/000360136","article-title":"The onset of lactase persistence in Europe","volume":"76","author":"Gerbault","year":"2013","journal-title":"Hum Hered"},{"key":"key20211014132752_b15-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1007\/s00439-012-1140-z","article-title":"The human lactase persistence-associated SNP-13910*T enables in vivo functional persistence of lactase promoter reported transgene expression","volume":"131","author":"Fang","year":"2012","journal-title":"Hum Genet"},{"key":"key20211014132752_b16-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1038\/ejcn.2016.80","article-title":"Perception of lactose intolerance impairs health-related quality of life","volume":"70","author":"Casellas","year":"2016","journal-title":"Eur J Clin Nutr"},{"key":"key20211014132752_b17-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1080\/00365520802588117","article-title":"Impact of molecularly defined hypolactasia, self-perceived milk intolerance and milk consumption on bone mineral density in a population sample in Northern Europe","volume":"44","author":"Kull","year":"2009","journal-title":"Scand J Gastroenterol"},{"key":"key20211014132752_b18-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00223-015-0062-x","article-title":"Effects of dairy products consumption on health: Benefits and beliefs-a commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases","volume":"98","author":"Rozenberg","year":"2016","journal-title":"Calcif Tissue Int"},{"key":"key20211014132752_b19-ETM-0-0-10768","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1042\/CS20070360","article-title":"Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: The Cardiovascular Risk in Young Finns Study","volume":"115","author":"Lehtim\u00e4ki","year":"2008","journal-title":"Clin Sci (Lond)"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T13:08:48Z","timestamp":1634216928000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2021.10768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,20]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,9,20]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2021.10768","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,20]]},"article-number":"1333"}}