{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:00:30Z","timestamp":1771261230051,"version":"3.50.1"},"reference-count":39,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2021.10956","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T08:29:24Z","timestamp":1636446564000},"source":"Crossref","is-referenced-by-count":4,"title":["Maternal and neonatal outcomes following <i>in\u00a0vitro<\/i> fertilization: A cohort study in Romania"],"prefix":"10.3892","volume":"23","author":[{"given":"Andreea","family":"B\u0103nic\u0103","sequence":"first","affiliation":[{"name":"Department 13 \u2011 Obstetrics\u2011Gynecology, Faculty of Medicine, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department 13 \u2011 Obstetrics\u2011Gynecology, Faculty of Medicine, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Vl\u0103d\u0103reanu","sequence":"additional","affiliation":[{"name":"Department 13 \u2011 Obstetrics\u2011Gynecology, Faculty of Medicine, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"issue":"hoaa032","key":"key20220302121050_b1-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoaa032","article-title":"ART in Europe, 2016: Results generated from European registries by ESHRE","volume":"2020","author":"Wyns","year":"2020","journal-title":"Hum Reprod Open"},{"key":"key20220302121050_b2-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00404-016-4250-3","article-title":"Worldwide prevalence of adverse pregnancy outcomes among singleton pregnancies after in vitro fertilization\/intracytoplasmic sperm injection: A systematic review and meta-analysis","volume":"295","author":"Qin","year":"2017","journal-title":"Arch Gynecol Obstet"},{"issue":"261","key":"key20220302121050_b3-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.37957.560278.EE","article-title":"Perinatal outcome of singletons and twins after assisted conception: A systematic review of controlled studies","volume":"328","author":"Helmerhorst","year":"2004","journal-title":"BMJ"},{"key":"key20220302121050_b4-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1056\/NEJMoa010806","article-title":"Low and very low birth weight in infants conceived with use of assisted reproductive technology","volume":"346","author":"Schieve","year":"2002","journal-title":"N Engl J Med"},{"key":"key20220302121050_b5-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1016\/j.fertnstert.2012.05.049","article-title":"Adverse obstetric and perinatal outcomes of singleton pregnancies may be related to maternal factors associated with infertility rather than the type of assisted reproductive technology procedure used","volume":"98","author":"Hayashi","year":"2012","journal-title":"Fertil Steril"},{"issue":"e80398","key":"key20220302121050_b6-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080398","article-title":"Perinatal outcomes by mode of assisted conception and sub-fertility in an Australian data linkage cohort","volume":"9","author":"Marino","year":"2014","journal-title":"PLoS One"},{"key":"key20220302121050_b7-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"2674","DOI":"10.1016\/j.fertnstert.2010.02.043","article-title":"Adverse obstetric and perinatal outcomes in subfertile women conceiving without assisted reproductive technologies","volume":"94","author":"Jaques","year":"2010","journal-title":"Fertil Steril"},{"key":"key20220302121050_b8-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"2408","DOI":"10.1097\/CM9.0000000000000484","article-title":"Perinatal complications and live-birth outcomes following assisted reproductive technology: A retrospective cohort study","volume":"132","author":"Lei","year":"2019","journal-title":"Chin Med J (Engl)"},{"key":"key20220302121050_b9-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1093\/humrep\/dev090","article-title":"Risk of hypertensive disorders in pregnancies following assisted reproductive technology: A cohort study from the CoNARTaS group","volume":"30","author":"Opdahl","year":"2015","journal-title":"Hum Reprod"},{"key":"key20220302121050_b10-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/jhh.2012.13","article-title":"Assisted reproductive technology and pregnancy-related hypertensive complications: A systematic review","volume":"27","author":"Thomopoulos","year":"2013","journal-title":"J Hum Hypertens"},{"key":"key20220302121050_b11-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"350.e1","DOI":"10.1016\/j.ajog.2019.10.003","article-title":"In vitro fertilization and risk for hypertensive disorders of pregnancy: Associations with treatment parameters","volume":"222","author":"Luke","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"key20220302121050_b12-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.fertnstert.2015.09.007","article-title":"Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: A meta-analysis of cohort studies","volume":"105","author":"Qin","year":"2016","journal-title":"Fertil Steril"},{"issue":"35141","key":"key20220302121050_b13-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1038\/srep35141","article-title":"Maternal and live-birth outcomes of pregnancies following assisted reproductive technology: A retrospective cohort study","volume":"6","author":"Zhu","year":"2016","journal-title":"Sci Rep"},{"key":"key20220302121050_b14-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1097\/01.AOG.0000114989.84822.51","article-title":"Perinatal outcomes in singletons following in vitro fertilization: A meta-analysis","volume":"103","author":"Jackson","year":"2004","journal-title":"Obstet Gynecol"},{"key":"key20220302121050_b15-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1940","DOI":"10.1080\/14767058.2017.1332035","article-title":"The association of placenta previa and assisted reproductive techniques: A meta-analysis","volume":"31","author":"Karami","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"key20220302121050_b16-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1093\/humupd\/dmx031","article-title":"Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?","volume":"24","author":"Maheshwari","year":"2018","journal-title":"Hum Reprod Update"},{"key":"key20220302121050_b17-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"433.e1","DOI":"10.1016\/j.ajog.2017.12.223","article-title":"Effect of frozen\/thawed embryo transfer on birthweight, macrosomia, and low birthweight rates in US singleton infants","volume":"218","author":"Litzky","year":"2018","journal-title":"Am J Obstet Gynecol"},{"issue":"19","key":"key20220302121050_b18-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00019","article-title":"Is embryo cryopreservation causing macrosomia-and what else?","volume":"11","author":"Orvieto","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"key20220302121050_b19-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1080\/14767058.2019.1602115","article-title":"Twin versus singleton pregnancy in women \u2265 45 years of age: Comparison of maternal and neonatal outcomes","volume":"34","author":"Avnon","year":"2021","journal-title":"J Matern Fetal Neonatal Med"},{"key":"key20220302121050_b20-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/1471-0528.15227","article-title":"Are singleton pregnancies after assisted reproduction technology (ART) associated with a higher risk of placental anomalies compared with non-ART singleton pregnancies? A systematic review and meta-analysis","volume":"126","author":"Vermey","year":"2019","journal-title":"BJOG"},{"key":"key20220302121050_b21-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1093\/humupd\/dmaa011","article-title":"Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: A systematic review and meta-analysis","volume":"26","author":"Bosdou","year":"2020","journal-title":"Hum Reprod Update"},{"key":"key20220302121050_b22-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.bpobgyn.2013.11.005","article-title":"Reducing multiple births in assisted reproduction technology","volume":"28","author":"Bhattacharya","year":"2014","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"key20220302121050_b23-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/j.fertnstert.2012.11.023","article-title":"Neonatal and maternal outcomes comparing women undergoing two in vitro fertilization (IVF) singleton pregnancies and women undergoing one IVF twin pregnancy","volume":"99","author":"Sazonova","year":"2013","journal-title":"Fertil Steril"},{"key":"key20220302121050_b24-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"56","DOI":"10.4103\/jhrs.JHRS_105_19","article-title":"Maternal and neonatal complications in twin deliveries as compared to singleton deliveries following in vitro fertilization","volume":"13","author":"Gupta","year":"2020","journal-title":"J Hum Reprod Sci"},{"key":"key20220302121050_b25-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/aogs.12328","article-title":"A comparison of perinatal outcomes in singletons and multiples born after in vitro fertilization or intracytoplasmic sperm injection stratified for neonatal risk criteria","volume":"93","author":"Van Heesch","year":"2014","journal-title":"Acta Obstet Gynecol Scand"},{"key":"key20220302121050_b26-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1056\/NEJMoa1008095","article-title":"Reproductive technologies and the risk of birth defects","volume":"366","author":"Davies","year":"2012","journal-title":"N Engl J Med"},{"issue":"343","key":"key20220302121050_b27-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-018-1984-x","article-title":"The effect of advanced maternal age on perinatal outcomes in nulliparous singleton pregnancies","volume":"18","author":"Kahveci","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"key20220302121050_b28-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1515\/jpm-2012-0097","article-title":"Perinatal risks after IVF and ICSI","volume":"41","author":"Zollner","year":"2013","journal-title":"J Perinat Med"},{"key":"key20220302121050_b29-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/j.fertnstert.2016.06.021","article-title":"Effect of maternal age on maternal and neonatal outcomes after assisted reproductive technology","volume":"106","author":"Wennberg","year":"2016","journal-title":"Fertil Steril"},{"issue":"w20499","key":"key20220302121050_b30-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2021.20499","article-title":"Single embryo transfer in all infertile couples treated with assisted reproduction produces excellent results and avoids multiple births","volume":"151","author":"De Geyter","year":"2021","journal-title":"Swiss Med Wkly"},{"key":"key20220302121050_b31-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1007\/s10815-018-1243-0","article-title":"Live birth and multiple birth rates in US in vitro fertilization treatment using donor oocytes: A comparison of single-embryo transfer and double-embryo transfer","volume":"35","author":"Klenov","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"key20220302121050_b32-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/j.fertnstert.2020.07.022","article-title":"Strategies to reduce multiple pregnancies during medically assisted reproduction","volume":"114","author":"Bergh","year":"2020","journal-title":"Fertil Steril"},{"issue":"CD003416","key":"key20220302121050_b33-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003416.pub5","article-title":"Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection","volume":"8","author":"Kamath","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"issue":"hoz038","key":"key20220302121050_b34-ETM-0-0-10956","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoz038","article-title":"ART in Europe, 2015: Results generated from European registries by ESHRE","volume":"2020","author":"De Geyter","year":"2020","journal-title":"Hum Reprod Open"},{"key":"key20220302121050_b35-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"3061","DOI":"10.1007\/s43032-021-00628-w","article-title":"When should we freeze embryos? current data for fresh and frozen embryo replacement IVF cycles","volume":"28","author":"Kalinderis","year":"2021","journal-title":"Reprod Sci"},{"key":"key20220302121050_b36-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.fertnstert.2012.05.019","article-title":"Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of frozen thawed versus fresh embryos generated through in vitro fertilization treatment: A systematic review and meta-analysis","volume":"98","author":"Maheshwari","year":"2012","journal-title":"Fertil Steril"},{"key":"key20220302121050_b37-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1016\/j.fertnstert.2016.08.047","article-title":"Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: An analysis of 112,432 singleton pregnancies recorded in the human fertilisation and embryology authority anonymized dataset","volume":"106","author":"Maheshwari","year":"2016","journal-title":"Fertil Steril"},{"key":"key20220302121050_b38-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1093\/humupd\/dmy033","article-title":"Fresh versus elective frozen embryo transfer in IVF\/ICSI cycles: A systematic review and meta-analysis of reproductive outcomes","volume":"25","author":"Roque","year":"2019","journal-title":"Hum Reprod Update"},{"key":"key20220302121050_b39-ETM-0-0-10956","doi-asserted-by":"publisher","first-page":"253","DOI":"10.5935\/1518-0557.20180049","article-title":"Obstetric outcomes after fresh versus frozen-thawed embryo transfers: A systematic review and meta-analysis","volume":"22","author":"Roque","year":"2018","journal-title":"JBRA Assist Reprod"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T10:14:16Z","timestamp":1646216056000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2021.10956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,9]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,11,9]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2021.10956","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,9]]},"article-number":"34"}}