{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T06:36:37Z","timestamp":1764570997474},"reference-count":63,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2021.11062","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T06:59:26Z","timestamp":1639465166000},"source":"Crossref","is-referenced-by-count":9,"title":["Transplantation of IL\u20111\u03b2 siRNA\u2011modified bone marrow mesenchymal stem cells ameliorates type\u00a0II collagen\u2011induced rheumatoid arthritis in rats"],"prefix":"10.3892","volume":"23","author":[{"given":"Shifeng","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiansheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuting","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Basic Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"key20220302122021_b1-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"335","DOI":"10.3892\/br.2017.855","article-title":"Association between interleukin-1 receptor associated kinase 1 rs3027898 A\/C gene polymorphism and rheumatoid arthritis","volume":"6","author":"Atabaki","year":"2017","journal-title":"Biomed Rep"},{"key":"key20220302122021_b2-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1016\/S0140-6736(10)60826-4","article-title":"Rheumatoid arthritis","volume":"376","author":"Scott","year":"2010","journal-title":"Lancet"},{"key":"key20220302122021_b3-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.jphs.2016.04.012","article-title":"The establishment of a porcine rheumatoid arthritis model: Collagen induced arthritis minipig model","volume":"132","author":"Lee","year":"2016","journal-title":"J Pharmacol Sci"},{"key":"key20220302122021_b4-ETM-0-0-11062","author":"Shea"},{"key":"key20220302122021_b5-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/j.ejmech.2018.09.027","article-title":"Side effects of methotrexate therapy for rheumatoid arthritis: A systematic review","volume":"158","author":"Wang","year":"2018","journal-title":"Eur J Med Chem"},{"key":"key20220302122021_b6-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1634\/theoncologist.2015-0164","article-title":"Preventing and managing toxicities of high-dose methotrexate","volume":"21","author":"Howard","year":"2016","journal-title":"Oncologist"},{"key":"key20220302122021_b7-ETM-0-0-11062","first-page":"281","article-title":"Autoantigens and immune pathways in rheumatoid arthritis","volume":"22","author":"Corrigall","year":"2002","journal-title":"Crit Rev Immunol"},{"key":"key20220302122021_b8-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/s1359-6101(02)00021-7","article-title":"Roles of IL-1 in the development of rheumatoid arthritis: Consideration from mouse models","volume":"13","author":"Iwakura","year":"2002","journal-title":"Cytokine Growth Factor Rev"},{"issue":"111","key":"key20220302122021_b9-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-017-1308-y","article-title":"Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis","volume":"19","author":"Shoda","year":"2017","journal-title":"Arthritis Res Ther"},{"key":"key20220302122021_b10-ETM-0-0-11062","doi-asserted-by":"crossref","first-page":"3604","DOI":"10.4049\/jimmunol.159.7.3604","article-title":"Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis","volume":"159","author":"Ghivizzani","year":"1997","journal-title":"J Immunol"},{"key":"key20220302122021_b11-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1038\/nrg908","article-title":"Gene silencing in mammals by small interfering RNAs","volume":"3","author":"McManus","year":"2002","journal-title":"Nat Rev Genet"},{"key":"key20220302122021_b12-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1038\/415331a","article-title":"Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity","volume":"415","author":"Shiver","year":"2002","journal-title":"Nature"},{"key":"key20220302122021_b13-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrm1129","article-title":"Killing the messenger: Short RNAs that silence gene expression","volume":"4","author":"Dykxhoorn","year":"2003","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20220302122021_b14-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/s1471-4914(03)00143-6","article-title":"Interfering with disease: Opportunities and roadblocks to harnessing RNA interference","volume":"9","author":"Lieberman","year":"2003","journal-title":"Trends Mol Med"},{"key":"key20220302122021_b15-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/nm828","article-title":"RNA interference targeting Fas protects mice from fulminant hepatitis","volume":"9","author":"Song","year":"2003","journal-title":"Nat Med"},{"key":"key20220302122021_b16-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1038\/452543a","article-title":"RNA interference: Generic block on angiogenesis","volume":"452","author":"Kalluri","year":"2008","journal-title":"Nature"},{"key":"key20220302122021_b17-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"3974","DOI":"10.1073\/pnas.0710629105","article-title":"ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity","volume":"105","author":"Okumura","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20220302122021_b18-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1007\/s11095-007-9504-0","article-title":"RNAi for treating hepatitis B viral infection","volume":"25","author":"Chen","year":"2008","journal-title":"Pharm Res"},{"key":"key20220302122021_b19-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.jconrel.2008.03.008","article-title":"Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer","volume":"129","author":"Kim","year":"2008","journal-title":"J Control Release"},{"key":"key20220302122021_b20-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1161\/CIRCRESAHA.117.311311","article-title":"RNA therapeutics in cardiovascular disease","volume":"123","author":"Lucas","year":"2018","journal-title":"Circ Res"},{"key":"key20220302122021_b21-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/cgt.2012.22","article-title":"Nanovector delivery of siRNA for cancer therapy","volume":"19","author":"Shen","year":"2012","journal-title":"Cancer Gene Ther"},{"key":"key20220302122021_b22-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0065-2660(05)54006-9","article-title":"In vivo application of RNA interference: From functional genomics to therapeutics","volume":"54","author":"Lu","year":"2005","journal-title":"Adv Genet"},{"key":"key20220302122021_b23-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1021\/ja044941d","article-title":"Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells","volume":"127","author":"Oishi","year":"2005","journal-title":"J Am Chem Soc"},{"key":"key20220302122021_b24-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1021\/bc050289f","article-title":"Comparative evaluation of target-specific GFP gene silencing efficiencies for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate","volume":"17","author":"Kim","year":"2006","journal-title":"Bioconjug Chem"},{"issue":"798","key":"key20220302122021_b25-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00798","article-title":"Mesenchymal stem cells improve rheumatoid arthritis progression by controlling memory T cell response","volume":"10","author":"Luque-Campos","year":"2019","journal-title":"Front Immunol"},{"key":"key20220302122021_b26-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ymeth.2015.09.015","article-title":"Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration","volume":"99","author":"Richardson","year":"2016","journal-title":"Methods"},{"issue":"78","key":"key20220302122021_b27-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.1186\/s12896-016-0306-5","article-title":"Repair of cartilage defects in osteoarthritis rats with induced pluripotent stem cell derived chondrocytes","volume":"16","author":"Zhu","year":"2016","journal-title":"BMC Biotechnol"},{"key":"key20220302122021_b28-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.ymthe.2003.10.012","article-title":"BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model","volume":"9","author":"Kurozumi","year":"2004","journal-title":"Mol Ther"},{"key":"key20220302122021_b29-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1038\/sj.gt.3302019","article-title":"Engineering mesenchymal stem cells for immunotherapy","volume":"10","author":"Jorgensen","year":"2003","journal-title":"Gene Ther"},{"key":"key20220302122021_b30-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"3838","DOI":"10.1182\/blood.v99.10.3838","article-title":"Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli","volume":"99","author":"Di Nicola","year":"2002","journal-title":"Blood"},{"issue":"1013","key":"key20220302122021_b31-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01013","article-title":"Anti-inflammatory effects of HDL in mice with rheumatoid arthritis induced by collagen","volume":"9","author":"Wang","year":"2018","journal-title":"Front Immunol"},{"key":"key20220302122021_b32-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1111\/j.1476-5381.1990.tb12720.x","article-title":"Methoxyphenamine inhibits basal and histamine-induced nasal congestion in anaesthetized rats","volume":"101","author":"Lau","year":"1990","journal-title":"Br J Pharmacol"},{"key":"key20220302122021_b33-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1590\/s0100-879x1997000700012","article-title":"Reactivity of the isolated perfused rat tail vascular bed","volume":"30","author":"Fran\u00e7a","year":"1997","journal-title":"Braz J Med Biol Res"},{"key":"key20220302122021_b34-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1248\/bpb.b14-00012","article-title":"Inhalation anesthesia is preferable for recording rat cardiac function using an electrocardiogram","volume":"37","author":"Murakami","year":"2014","journal-title":"Biol Pharm Bull"},{"key":"key20220302122021_b35-ETM-0-0-11062","first-page":"127","article-title":"Effects of anaesthesia on insulin sensitivity and metabolic parameters in Wistar rats","volume":"27","author":"Guarino","year":"2013","journal-title":"In Vivo"},{"issue":"285","key":"key20220302122021_b36-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00285","article-title":"Type I interferon gene response is increased in early and established rheumatoid arthritis and correlates with autoantibody production","volume":"8","author":"Casta\u00f1eda-Delgado","year":"2017","journal-title":"Front Immunol"},{"key":"key20220302122021_b37-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20220302122021_b38-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1084\/jem.146.3.857","article-title":"Autoimmunity to type II collagen an experimental model of arthritis","volume":"146","author":"Trentham","year":"1977","journal-title":"J Exp Med"},{"key":"key20220302122021_b39-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1006\/jaut.2000.0378","article-title":"Dimethyl dioctadecyl ammonium bromide (DDA)-induced arthritis in rats: A model of experimental arthritis","volume":"14","author":"Mia","year":"2000","journal-title":"J Autoimmun"},{"key":"key20220302122021_b40-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/s0306-3623(96)00561-7","article-title":"Adjuvant-carrageenan-induced inflammation in mice","volume":"29","author":"Silv\u00e1n","year":"1997","journal-title":"Gen Pharmacol"},{"key":"key20220302122021_b41-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1600-065x.1990.tb00817.x","article-title":"Type II collagen autoimmunity in animals and provocations leading to arthritis","volume":"118","author":"Holmdahl","year":"1990","journal-title":"Immunol Rev"},{"key":"key20220302122021_b42-ETM-0-0-11062","first-page":"498","article-title":"Age-related differences in collagen-induced arthritis: Clinical and imaging correlations","volume":"63","author":"Wilson-Gerwing","year":"2013","journal-title":"Comp Med"},{"key":"key20220302122021_b43-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"ii3","DOI":"10.1093\/rheumatology\/keg326","article-title":"The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis","volume":"42 (Suppl 2)","author":"Dayer","year":"2003","journal-title":"Rheumatology (Oxford)"},{"key":"key20220302122021_b44-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"61","DOI":"10.26355\/eurrev_201901_16748","article-title":"Expression of T follicular helper lymphocytes with different subsets and analysis of serum IL-6, IL-17, TGF-\u03b2 and MMP-3 contents in patients with rheumatoid arthritis","volume":"23","author":"Sun","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"key20220302122021_b45-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/3-540-37673-9_8","article-title":"The role of TNFalpha and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice","author":"Ishigame","year":"2006","journal-title":"Ernst Schering Res Found Workshop"},{"issue":"108158","key":"key20220302122021_b46-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108158","article-title":"The natural compound notopterol binds and targets JAK2\/3 to ameliorate inflammation and arthritis","volume":"32","author":"Wang","year":"2020","journal-title":"Cell Rep"},{"key":"key20220302122021_b47-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1517\/14712598.1.5.817","article-title":"Anticytokine therapy for osteoarthritis","volume":"1","author":"Goldring","year":"2001","journal-title":"Expert Opin Biol Ther"},{"key":"key20220302122021_b48-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.cca.2016.02.010","article-title":"Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis","volume":"455","author":"Mateen","year":"2016","journal-title":"Clin Chim Acta"},{"key":"key20220302122021_b49-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/s1074-7613(00)80089-8","article-title":"Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor","volume":"11","author":"Nishimura","year":"1999","journal-title":"Immunity"},{"key":"key20220302122021_b50-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1002\/art.27500","article-title":"The programmed death 1\/programmed death ligand 1 inhibitory pathway is up-regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis","volume":"62","author":"Raptopoulou","year":"2010","journal-title":"Arthritis Rheum"},{"key":"key20220302122021_b51-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1126\/science.1079490","article-title":"Control of regulatory T cell development by the transcription factor Foxp3","volume":"299","author":"Hori","year":"2003","journal-title":"Science"},{"key":"key20220302122021_b52-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.bbrc.2009.06.150","article-title":"Small interfering RNA targeting CD81 ameliorated arthritis in rats","volume":"388","author":"Nakagawa","year":"2009","journal-title":"Biochem Biophys Res Commun"},{"key":"key20220302122021_b53-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10165-008-0131-3","article-title":"Comparison of anti-rheumatic effects of local RNAi-based therapy in collagen induced arthritis rats using various cytokine genes as molecular targets","volume":"19","author":"Inoue","year":"2009","journal-title":"Mod Rheumatol"},{"key":"key20220302122021_b54-ETM-0-0-11062","first-page":"269","article-title":"Stem cell factor inhibits erythroid differentiation by modulating the activity of G1-cyclin-dependent kinase complexes: A role for p27 in erythroid differentiation coupled G1 arrest","volume":"11","author":"Tamir","year":"2000","journal-title":"Cell Growth Differ"},{"key":"key20220302122021_b55-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/nature00870","article-title":"Pluripotency of mesenchymal stem cells derived from adult marrow","volume":"418","author":"Jiang","year":"2002","journal-title":"Nature"},{"key":"key20220302122021_b56-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1111\/eos.12533","article-title":"Effect of bone marrow mesenchymal stem cells on healing of temporomandibular joints in rats with induced rheumatoid arthritis","volume":"126","author":"El Qashty","year":"2018","journal-title":"Eur J Oral Sci"},{"key":"key20220302122021_b57-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1002\/bit.26273","article-title":"Complex mechanical conditioning of cell-seeded agarose constructs can influence chondrocyte biosynthetic activity","volume":"114","author":"DiFederico","year":"2017","journal-title":"Biotechnol Bioeng"},{"key":"key20220302122021_b58-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"Smolen","year":"2016","journal-title":"Lancet"},{"key":"key20220302122021_b59-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/s10561-013-9369-x","article-title":"Repairing cartilage defects with bone marrow mesenchymal stem cells induced by CDMP and TGF-\u03b21","volume":"15","author":"Wu","year":"2014","journal-title":"Cell Tissue Bank"},{"key":"key20220302122021_b60-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1146\/annurev.immunol.14.1.397","article-title":"Role of cytokines in rheumatoid arthritis","volume":"14","author":"Feldmann","year":"1996","journal-title":"Annu Rev Immunol"},{"issue":"e111163","key":"key20220302122021_b61-ETM-0-0-11062","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0111163","article-title":"Functional improvement of regulatory T cells from rheumatoid arthritis subjects induced by capsular polysaccharide glucuronoxylomannogalactan","volume":"9","author":"Pericolini","year":"2014","journal-title":"PLoS One"},{"key":"key20220302122021_b62-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1164\/ajrccm.163.4.9907078","article-title":"Absorption, distribution, metabolism, and excretion of a respirable antisense oligonucleotide for asthma","volume":"163","author":"Ali","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"key20220302122021_b63-ETM-0-0-11062","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1067\/mai.2003.179","article-title":"Modulation of allergic response in nasal mucosa by antisense oligodeoxynucleotides for IL-4","volume":"111","author":"Fiset","year":"2003","journal-title":"J Allergy Clin Immunol"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T07:35:19Z","timestamp":1674027319000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2021.11062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":63,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,12,14]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2021.11062","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,14]]},"article-number":"139"}}