{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T08:19:31Z","timestamp":1775031571069,"version":"3.50.1"},"reference-count":38,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2022.11138","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T16:45:00Z","timestamp":1644425100000},"source":"Crossref","is-referenced-by-count":7,"title":["Ophthalmic herpes zoster with severe complications in an immunocompromised patient: A case report and review of the literature"],"prefix":"10.3892","volume":"23","author":[{"given":"Gabriela","family":"Iancu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Lucian Blaga University, 550169 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"St\u0103nil\u0103","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Lucian Blaga University, 550169 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remus","family":"Cip\u0103ian","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Lucian Blaga University, 550169 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Rotaru","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Lucian Blaga University, 550169 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"key":"key20220302115737_b1-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1016\/j.ophtha.2016.03.005","article-title":"Epidemiology of herpes zoster ophtalmicus: Recurrence and chronicity","volume":"123","author":"Tran","year":"2016","journal-title":"Ophtalmology"},{"key":"key20220302115737_b2-ETM-0-0-11138","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1001\/archinte.1997.00440320105010","article-title":"The sequelae of herpes zoster","volume":"157","author":"Galil","year":"1997","journal-title":"Arch Intern Med"},{"key":"key20220302115737_b3-ETM-0-0-11138","first-page":"1723","article-title":"Evaluation and management of herpes zoster ophthalmicus","volume":"66","author":"Shaikh","year":"2002","journal-title":"Am Fam Physician"},{"key":"key20220302115737_b4-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1086\/510206","article-title":"Recommendations for the management of herpes zoster","volume":"44 (Suppl 1)","author":"Dworkin","year":"2007","journal-title":"Clin Infect Dis"},{"key":"key20220302115737_b5-ETM-0-0-11138","first-page":"35","article-title":"Herpes zoster ophthalmicus in HIV\/AIDS","volume":"16","author":"Wiafe","year":"2003","journal-title":"Community Eye Health"},{"key":"key20220302115737_b6-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1136\/bmj.331.7509.147","article-title":"Managing ophthalmic herpes zoster in primary care","volume":"331","author":"Opstelten","year":"2005","journal-title":"BMJ"},{"key":"key20220302115737_b7-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1111\/apt.12182","article-title":"Increased risk of herpes zoster among 108 604 patients with inflammatory bowel disease","volume":"37","author":"Long","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"key20220302115737_b8-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1111\/j.1468-3083.2006.02009.x","article-title":"Ambilateral reactivation of herpes zoster V2 following cataract operation of both eyes","volume":"21","author":"Korber","year":"2007","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"key20220302115737_b9-ETM-0-0-11138","doi-asserted-by":"crossref","DOI":"10.5070\/D36FZ6C3R8","article-title":"Facial cellulitis associated with complicating ophthalmic herpes zoster","volume":"10","author":"Atzori","year":"2004","journal-title":"Dermatol Online J"},{"key":"key20220302115737_b10-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"733","DOI":"10.4103\/0301-4738.171006","article-title":"Herpes zoster ophthalmicus presenting as orbital abscess along with superior orbital fissure syndrome: A case report","volume":"63","author":"Lavaju","year":"2015","journal-title":"Indian J Ophthalmol"},{"issue":"28","key":"key20220302115737_b11-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.21037\/aes-2019-dmu-09","article-title":"Advances in the diagnosis and management of acute retinal necrosis","volume":"5","author":"Anthony","year":"2020","journal-title":"Ann Eye Sci"},{"key":"key20220302115737_b12-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s00417-002-0609-1","article-title":"Prognostic value of Hutchinson's sign in acute herpes zoster ophthalmicus","volume":"241","author":"Zaal","year":"2003","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"key20220302115737_b13-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"S24","DOI":"10.1002\/jmv.10316","article-title":"A study of shingles and the development of postherpetic neuralgia in East London","volume":"70 (Suppl 1)","author":"Scott","year":"2003","journal-title":"J Med Virol"},{"key":"key20220302115737_b14-ETM-0-0-11138","doi-asserted-by":"crossref","first-page":"119","DOI":"10.17925\/USOR.2013.06.02.1","article-title":"Herpes zoster ophthalmicus-diagnosis and management","volume":"6","author":"Rousseau","year":"2013","journal-title":"US Ophthalm Rev"},{"key":"key20220302115737_b15-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.ophtha.2007.10.009","article-title":"Herpes zoster ophthalmicus natural history, risk factors, clinical presentation, and morbidity","volume":"115 (Suppl 2)","author":"Liesegang","year":"2008","journal-title":"Ophthalmology"},{"key":"key20220302115737_b16-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1056\/NEJMcp013211","article-title":"Clinical practice. Herpes zoster","volume":"347","author":"Gnann","year":"2002","journal-title":"N Engl J Med"},{"issue":"20587384211002621","key":"key20220302115737_b17-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1177\/20587384211002621","article-title":"A review: Mechanism of action antiviral drugs","volume":"35","author":"Kausar","year":"2021","journal-title":"Int J Immunopathol Pharmacol"},{"issue":"e00642","key":"key20220302115737_b18-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2019.e00642","article-title":"A case of tri-segmental cranial nerve V herpes zoster","volume":"18","author":"Cheema","year":"2019","journal-title":"IDCases"},{"key":"key20220302115737_b19-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"E19","DOI":"10.1002\/jhm.460","article-title":"Meningoencephalitis-complicating herpes zoster ophthalmicus infection","volume":"4","author":"Srinivasan","year":"2009","journal-title":"J Hosp Med"},{"key":"key20220302115737_b20-ETM-0-0-11138","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.optom.2012.08.005","article-title":"Herpes zoster ophthalmicus-induced oculomotor nerve palsy","volume":"6","author":"Harthan","year":"2013","journal-title":"J Optom"},{"issue":"bcr2012007625","key":"key20220302115737_b21-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-007625","article-title":"Ophthalmic manifestations of herpes zoster virus in patients with multiple myeloma following bone marrow transplantation","volume":"2013","author":"Khalafallah","year":"2013","journal-title":"BMJ Case Rep"},{"key":"key20220302115737_b22-ETM-0-0-11138","first-page":"27","article-title":"Cerebral venous sinus thrombosis resulting from herpes zoster infection in an older adult","volume":"24","author":"Rajkumar","year":"2016","journal-title":"Ann Longterm Care Clin Care Aging"},{"issue":"7605056","key":"key20220302115737_b23-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7605056","article-title":"Brainstem and cerebellar involvement in Ramsay Hunt syndrome","volume":"2019","author":"Letchuman","year":"2019","journal-title":"Case Rep Otolaryngol"},{"key":"key20220302115737_b24-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1080\/17843286.2018.1517076","article-title":"Ramsay Hunt syndrome: A rare complication of herpes zoster infection in a lung cancer patient","volume":"74","author":"Mercier","year":"2019","journal-title":"Acta Clin Belg"},{"key":"key20220302115737_b25-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.idcr.2016.10.003","article-title":"Concurrent Ramsay Hunt syndrome and disseminated herpes zoster in a patient with relapsed chronic lymphocytic leukemia","volume":"8","author":"Chen","year":"2016","journal-title":"IDCases"},{"issue":"4082","key":"key20220302115737_b26-ETM-0-0-11138","article-title":"Acute orbital syndrome in herpes zoster ophthalmicus","volume":"55","author":"Pointdujour","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key20220302115737_b27-ETM-0-0-11138","first-page":"153","article-title":"Cicatricial ectropion due to herpes zoster ophthalmicus","volume":"52","author":"Sanghvi","year":"2006","journal-title":"J Postgrad Med"},{"issue":"e15651","key":"key20220302115737_b28-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015651","article-title":"A case report of double etiology of ecthyma gangrenosum: Pseudomonas aeruginosa and Enterococcus faecalis in an immunocompromised child occurred during influenza evolution","volume":"98","author":"Birlutiu","year":"2019","journal-title":"Medicine (Baltimore)"},{"key":"key20220302115737_b29-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"302","DOI":"10.3341\/kjo.2005.19.4.302","article-title":"A case of complete ophthalmoplegia in herpes zoster ophthalmicus","volume":"19","author":"Shin","year":"2005","journal-title":"Korean J Ophthalmol"},{"key":"key20220302115737_b30-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"205","DOI":"10.17085\/apm.2020.15.2.205","article-title":"Herpes zoster in the ophthalmic branch of the trigeminal ganglia obscuring cavernous sinus thrombosis due to streptococcus constellatus subsp. Constellatus-a case report","volume":"15","author":"Lee","year":"2020","journal-title":"Anesth Pain Med (Seoul)"},{"key":"key20220302115737_b31-ETM-0-0-11138","first-page":"24","article-title":"When herpes causes 3rd nerve palsy, patients and practitioners suddenly have to deal with multiple issues","volume":"153","author":"Trottini","year":"2016","journal-title":"Rev Optom"},{"issue":"74","key":"key20220302115737_b32-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-14-74","article-title":"A case of herpes zoster uveitis with severe hyphema","volume":"14","author":"Okuniki","year":"2014","journal-title":"BMC Ophthalmol"},{"key":"key20220302115737_b33-ETM-0-0-11138","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1076\/0927-3948(200006)821-0FT115","article-title":"Herpes zoster sine herpete presenting with hyphema","volume":"8","author":"Akpek","year":"2000","journal-title":"Ocul Immunol Inflamm"},{"key":"key20220302115737_b34-ETM-0-0-11138","doi-asserted-by":"crossref","first-page":"1","DOI":"10.24018\/ejmed.2021.3.5.1010","article-title":"Herpes zoster anterior uveitis and hyphema","volume":"3","author":"Arvinth","year":"2021","journal-title":"Eur J Medical Health Sci"},{"key":"key20220302115737_b35-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1159\/000309898","article-title":"Herpes zoster ophthalmicus complicated by hyphema and hemorrhagic glaucoma","volume":"196","author":"Hayasaka","year":"1988","journal-title":"Ophtalmologica"},{"key":"key20220302115737_b36-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"54","DOI":"10.4103\/tjo.tjo_20_18","article-title":"Herpes zoster keratouveitis with hypopyon and hyphema","volume":"10","author":"Katherine","year":"2020","journal-title":"Taiwan J Ophthalmol"},{"issue":"33","key":"key20220302115737_b37-ETM-0-0-11138","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-0760-z","article-title":"Orbital apex syndrome: An unusual complication of herpes zoster ophthalmicus","volume":"15","author":"Lee","year":"2015","journal-title":"BMC Infect Dis"},{"key":"key20220302115737_b38-ETM-0-0-11138","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1212\/WNL.0000000000002808","article-title":"Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study","volume":"87","author":"Forbes","year":"2016","journal-title":"Neurology"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T09:57:56Z","timestamp":1646215076000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2022.11138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,11]]},"references-count":38,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,1,11]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2022.11138","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,11]]},"article-number":"214"}}