{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T02:20:15Z","timestamp":1770603615058,"version":"3.49.0"},"reference-count":52,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2022.11143","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T16:45:56Z","timestamp":1644425156000},"source":"Crossref","is-referenced-by-count":8,"title":["Pituitary adenoma apoplexy in pregnancy: Case report and literature review"],"prefix":"10.3892","volume":"23","author":[{"given":"Lucian","family":"Pop","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, National Institute of Mother and Child Care, 400012 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Ilian","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Victor Babes\u2019 University of Medicine and Pharmacy, 300014 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiberiu","family":"Georgescu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, National Institute of Mother and Child Care, 400012 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolae","family":"Bacalbasa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Balescu","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u2018Ponderas\u2019 Academic Hospital, 021188 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oana","family":"Toader","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, National Institute of Mother and Child Care, 400012 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2022,1,14]]},"reference":[{"key":"key20220302115747_b1-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1007\/BF03022061","article-title":"The incidence and etiology of postpartum headaches: A prospective cohort study","volume":"52","author":"Goldszmidt","year":"2005","journal-title":"Can J Anaesth"},{"key":"key20220302115747_b2-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/s0002-9343(88)80346-2","article-title":"Pituitary gland growth during normal pregnancy: An in vivo study using magnetic resonance imaging","volume":"85","author":"Gonzalez","year":"1988","journal-title":"Am J Med"},{"key":"key20220302115747_b3-ETM-0-0-11143","author":"Chestnut"},{"issue":"e228323","key":"key20220302115747_b4-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-228323","article-title":"Visual loss in pregnancy","volume":"12","author":"Bachmeier","year":"2019","journal-title":"BMJ Case Rep"},{"key":"key20220302115747_b5-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1210\/jc.2010-1048","article-title":"Pituitary incidentaloma: An endocrine society clinical practice guideline","volume":"96","author":"Freda","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key20220302115747_b6-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1001\/jama.2016.19699","article-title":"Diagnosis and treatment of pituitary adenomas: A Review","volume":"317","author":"Molitch","year":"2017","journal-title":"JAMA"},{"key":"key20220302115747_b7-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1177\/1753495X15598917","article-title":"Pituitary apoplexy in pregnancy: A case series and literature review","volume":"8","author":"Grand'Maison","year":"2015","journal-title":"Obstet Med"},{"key":"key20220302115747_b8-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.beem.2010.03.001","article-title":"The genetics of pituitary adenomas","volume":"24","author":"Vandeva","year":"2010","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"key20220302115747_b9-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1007\/s40618-014-0095-4","article-title":"Pituitary apoplexy during pregnancy: A rare, but dangerous headache","volume":"37","author":"Piantanida","year":"2014","journal-title":"J Endocrinol Invest"},{"key":"key20220302115747_b10-ETM-0-0-11143","first-page":"393","article-title":"Pituitary apoplexy presenting during pregnancy","volume":"62","author":"de Heide","year":"2004","journal-title":"Neth J Med"},{"key":"key20220302115747_b11-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1097\/AOG.0b013e3181c2bde8","article-title":"Pregnancy and laboratory studies: A reference table for clinicians","volume":"114","author":"Abbassi-Ghanavati","year":"2009","journal-title":"Obstet Gynecol"},{"key":"key20220302115747_b12-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"S188","DOI":"10.4103\/2230-8210.84862","article-title":"Pituitary apoplexy","volume":"15 (Suppl 3)","author":"Ranabir","year":"2011","journal-title":"Indian J Endocrinol Metab"},{"key":"key20220302115747_b13-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3109\/09513590903184118","article-title":"Hyponatremia associated coma due to pituitary apoplexy in early pregnancy: A case report","volume":"26","author":"Krull","year":"2010","journal-title":"Gynecol Endocrinol"},{"key":"key20220302115747_b14-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3340\/jkns.2011.50.4.281","article-title":"Radiological apoplexy and its correlation with acute clinical presentation, angiogenesis and tumor microvascular density in pituitary adenomas","volume":"50","author":"Lee","year":"2011","journal-title":"J Korean Neurosurg Soc"},{"key":"key20220302115747_b15-ETM-0-0-11143","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/tog.12604","article-title":"Imaging in pregnancy","volume":"21","author":"Eastwood","year":"2019","journal-title":"Obstetrician Gynaecol"},{"issue":"43","key":"key20220302115747_b16-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1258\/shorts.2012.011144","article-title":"Management of pituitary tumour apoplexy with bromocriptine in pregnancy","volume":"3","author":"Janssen","year":"2012","journal-title":"JRSM Short Rep"},{"key":"key20220302115747_b17-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1080\/09513590.2019.1650339","article-title":"A case of atypical macroprolactinoma presenting with pituitary apoplexy during pregnancy and review of the literature","volume":"36","author":"Oguz","year":"2020","journal-title":"Gynecol Endocrinol"},{"key":"key20220302115747_b18-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1055\/s-2005-873004","article-title":"Follow-up of pregnancy in acromegalic women: Different presentations and outcomes","volume":"114","author":"Atmaca","year":"2006","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"key20220302115747_b19-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/0020-7292(91)90542-d","article-title":"Pituitary apoplexy in an acromegalic woman operated on during pregnancy by transphenoidal approach","volume":"34","author":"Lunardi","year":"1991","journal-title":"Int J Gynaecol Obstet"},{"key":"key20220302115747_b20-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1177\/0310057X0603400111","article-title":"An unusual presentation of a pituitary tumour in the early postpartum period","volume":"34","author":"Paech","year":"2006","journal-title":"Anaesth Intensive Care"},{"issue":"6350","key":"key20220302115747_b21-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-2-9117","article-title":"Management of pituitary adenoma with mass effect in pregnancy: A case report","volume":"2","author":"Okafor","year":"2009","journal-title":"Cases J"},{"issue":"bcr2015212405","key":"key20220302115747_b22-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-212405","article-title":"Spontaneous pituitary apoplexy during the second trimester of pregnancy, with sensory loss","volume":"2016","author":"Abraham","year":"2016","journal-title":"BMJ Case Rep"},{"key":"key20220302115747_b23-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/s0015-0282(16)55219-4","article-title":"Pregnancy-associated subacute hemorrhage into a prolactinoma resulting in diabetes insipidus","volume":"58","author":"Freeman","year":"1992","journal-title":"Fertil Steril"},{"issue":"e10","key":"key20220302115747_b24-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMicm0900500","article-title":"Images in clinical medicine. Gestational pituitary-tumor apoplexy","volume":"363","author":"Ginath","year":"2010","journal-title":"N Engl J Med"},{"key":"key20220302115747_b25-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1055\/s-2003-40734","article-title":"Minimally invasive pituitary surgery in a hemorrhagic necrosis of adenoma during pregnancy","volume":"46","author":"Gondim","year":"2003","journal-title":"Minim Invasive Neurosurg"},{"issue":"140043","key":"key20220302115747_b26-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-14-0043","article-title":"A case of pituitary apoplexy in pregnancy","volume":"2014","author":"Hayes","year":"2014","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"key20220302115747_b27-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/j.jogoh.2019.05.005","article-title":"Gestational pituitary apoplexy: Case series and review of the literature","volume":"48","author":"Jemel","year":"2019","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"key20220302115747_b28-ETM-0-0-11143","first-page":"107","article-title":"Postoperative diabetes insipidus associated with pituitary apoplexy during pregnancy","volume":"33","author":"Kita","year":"2012","journal-title":"Neuro Endocrinol Lett"},{"key":"key20220302115747_b29-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/s0015-0282(16)44050-1","article-title":"The incidence of complications during pregnancy after treatment of hyperprolactinemia with bromocriptine in patients with radiologically evident pituitary tumors","volume":"31","author":"Lamberts","year":"1979","journal-title":"Fertil Steril"},{"key":"key20220302115747_b30-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3171\/jns.2003.98.1.0183","article-title":"Apoplectic lymphocytic hypophysitis. Case report","volume":"98","author":"Lee","year":"2003","journal-title":"J Neurosurg"},{"key":"key20220302115747_b31-ETM-0-0-11143","first-page":"389","article-title":"Apoplexy into a prolactin secreting macroadenoma during early pregnancy with successful outcome. Case report","volume":"93","author":"O'Donovan","year":"1986","journal-title":"Br J Obstet Gynaecol"},{"key":"key20220302115747_b32-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1136\/practneurol-2016-001589","article-title":"Headaches complicating pregnancy and the postpartum period","volume":"17","author":"O'Neal","year":"2017","journal-title":"Pract Neurol"},{"key":"key20220302115747_b33-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/j.jocn.2010.03.002","article-title":"Post-partum pituitary apoplexy with bilateral third nerve palsy and bilateral carotid occlusion","volume":"17","author":"Perotti","year":"2010","journal-title":"J Clin Neurosci"},{"key":"key20220302115747_b34-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.endonu.2015.01.007","article-title":"Pituitary apoplexy in a pregnant woman with cystic microprolactinoma","volume":"62","author":"Querol Ripoll","year":"2015","journal-title":"Endocrinol Nutr"},{"key":"key20220302115747_b35-ETM-0-0-11143","first-page":"483","article-title":"Transsphenoidal surgery for a life-threatening prolactinoma apoplexy during pregnancy","volume":"33","author":"Witek","year":"2012","journal-title":"Neuro Endocrinol Lett"},{"key":"key20220302115747_b36-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"484","DOI":"10.4103\/ijem.IJEM_8_17","article-title":"Gestational pituitary apoplexy","volume":"21","author":"Annamalai","year":"2017","journal-title":"Indian J Endocrinol Metab"},{"issue":"662","key":"key20220302115747_b37-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2011.590911","article-title":"A case of pituitary apoplexy masquerading as hyperemesis gravidarum","volume":"31","author":"Bamfo","year":"2011","journal-title":"J Obstet Gynaecol"},{"issue":"211","key":"key20220302115747_b38-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2014.17.211.4133","article-title":"Pituitary apoplexy during pregnancy","volume":"17","author":"Chegour","year":"2014","journal-title":"Pan Afr Med J"},{"key":"key20220302115747_b39-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"e147","DOI":"10.4158\/EP12106.CR","article-title":"Apoplexy of a microprolactinoma during pregnancy: Case report and review of literature","volume":"18","author":"Couture","year":"2012","journal-title":"Endocr Pract"},{"key":"key20220302115747_b40-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1055\/s-0031-1293542","article-title":"Management of pituitary tumors in pregnancy","volume":"31","author":"Iuliano","year":"2011","journal-title":"Semin Neurol"},{"key":"key20220302115747_b41-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"54","DOI":"10.4103\/0972-2327.48861","article-title":"Pituitary apoplexy in a pregnant woman","volume":"12","author":"Parihar","year":"2009","journal-title":"Ann Indian Acad Neurol"},{"issue":"bcr2015210198","key":"key20220302115747_b42-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-210198","article-title":"An unexpected headache: Pituitary apoplexy in a pregnant woman on anticoagulation","volume":"2015","author":"Watson","year":"2015","journal-title":"BMJ Case Rep"},{"key":"key20220302115747_b43-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1179\/016164105X17341","article-title":"Pituitary apoplexy as a consequence of lymphocytic adenohypophysitis in a pregnant woman: A case report","volume":"27","author":"Fujimaki","year":"2005","journal-title":"Neurol Res"},{"key":"key20220302115747_b44-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.fertnstert.2011.05.012","article-title":"Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome with pituitary apoplexy","volume":"96","author":"Murao","year":"2011","journal-title":"Fertil Steril"},{"key":"key20220302115747_b45-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/MAJ.0b013e31821e0e91","article-title":"Headache, pituitary lesion and panhypopituitarism in a pregnant woman: Tumor, apoplexy or hypophysitis?","volume":"342","author":"Tonda","year":"2011","journal-title":"Am J Med Sci"},{"key":"key20220302115747_b46-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1080\/01443615.2016.1233946","article-title":"Prolactinoma and pregnancy-a series of cases including pituitary apoplexy","volume":"37","author":"Galvao","year":"2017","journal-title":"J Obstet Gynaecol"},{"key":"key20220302115747_b47-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.crwh.2015.09.001","article-title":"Approach to the management of rare clinical presentations of macroprolactinomas in reproductive-aged women","volume":"8","author":"De Ycaza","year":"2015","journal-title":"Case Rep Womens Health"},{"issue":"h4681","key":"key20220302115747_b48-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h4681","article-title":"An unusual cause of headache in pregnancy","volume":"351","author":"Bedford","year":"2015","journal-title":"BMJ"},{"issue":"397131","key":"key20220302115747_b49-ETM-0-0-11143","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/397131","article-title":"Endoscopic endonasal transsphenoidal resection for pituitary apoplexy during the third trimester of pregnancy","volume":"2014","author":"Tandon","year":"2014","journal-title":"Surg Res Pract"},{"key":"key20220302115747_b50-ETM-0-0-11143","author":"Gheorghiu"},{"key":"key20220302115747_b51-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1177\/0310057X1404200118","article-title":"Pituitary apoplexy with reversible cerebral vasoconstrictive syndrome after spinal anaesthesia for emergency caesarean section: An uncommon cause for postpartum headache","volume":"42","author":"Mathur","year":"2014","journal-title":"Anaesth Intensive Care"},{"key":"key20220302115747_b52-ETM-0-0-11143","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1365-2265.2010.03913.x","article-title":"UK guidelines for the management of pituitary apoplexy","volume":"74","author":"Rajasekaran","year":"2011","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T09:57:57Z","timestamp":1646215077000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2022.11143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,14]]},"references-count":52,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,1,14]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2022.11143","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,14]]},"article-number":"218"}}