{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:22:33Z","timestamp":1787030553170,"version":"build-2736575974"},"reference-count":42,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2025.13043","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T07:05:05Z","timestamp":1764918305000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review"],"prefix":"10.3892","volume":"31","author":[{"given":"Chenao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baicheng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingdong","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shili","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"issue":"500","key":"key20260114113208_b1-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2024.14633","article-title":"Diagnostic difficulties in the differentiation between an ovarian metastatic low-grade appendiceal mucinous neoplasm and primary ovarian mucinous cancer: A case report and literature review","volume":"28","author":"Kawecka","year":"2024","journal-title":"Oncol Lett"},{"key":"key20260114113208_b2-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/modpathol.3880572","article-title":"Mucinous and nonmucinous appendiceal adenocarcinomas: Different clinicopathological features but similar genetic alterations","volume":"15","author":"Kabbani","year":"2002","journal-title":"Mod Pathol"},{"issue":"1179","key":"key20260114113208_b3-ETM-31-2-13043","article-title":"A specimen of \u2018auto-amputation\u2019 of the appendix","volume":"65","author":"Judd","year":"1915","journal-title":"JAMA"},{"key":"key20260114113208_b4-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1634\/theoncologist.2017-0081","article-title":"Appendiceal mucinous neoplasms: Diagnosis and management","volume":"22","author":"Shaib","year":"2017","journal-title":"Oncologist"},{"key":"key20260114113208_b5-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.asjsur.2020.05.010","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal and appendiceal peritoneal metastases-The Hong Kong experience and literature review","volume":"44","author":"Chow","year":"2021","journal-title":"Asian J Surg"},{"key":"key20260114113208_b6-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.ejca.2019.10.034","article-title":"Indications for hyperthermic intraperitoneal chemotherapy with cytoreductive surgery: A systematic review","volume":"127","author":"Auer","year":"2020","journal-title":"Eur J Cancer"},{"key":"key20260114113208_b7-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1136\/jim-2018-000975","article-title":"Low-grade appendiceal mucinous neoplasms confined to the appendix: Clinical manifestations and CT findings","volume":"68","author":"Yu","year":"2020","journal-title":"J Investig Med"},{"key":"key20260114113208_b8-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ejso.2020.02.012","article-title":"Appendiceal tumours and pseudomyxoma peritonei: Literature review with PSOGI\/EURACAN clinical practice guidelines for diagnosis and treatment","volume":"47","author":"Govaerts","year":"2021","journal-title":"Eur J Surg Oncol"},{"key":"key20260114113208_b9-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1080\/09593985.2024.2315517","article-title":"Low back pain as main symptom in Low-grade Appendiceal Mucinous Neoplasm (LAMN): A case report","volume":"41","author":"Mannarini","year":"2025","journal-title":"Physiother Theory Pract"},{"issue":"rjad273","key":"key20260114113208_b10-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjad273","article-title":"A giant low-grade appendiceal mucinous neoplasm (LAMN) presenting as ileocecal intussusception: A case report","volume":"2023","author":"Liapis","year":"2023","journal-title":"J Surg Case Rep"},{"key":"key20260114113208_b11-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.ijscr.2018.08.001","article-title":"Intestinal obstruction caused by Low-grade appendiceal mucinous neoplasm: A case report and review of the literature","volume":"51","author":"Komo","year":"2018","journal-title":"Int J Surg Case Rep"},{"key":"key20260114113208_b12-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1097\/00004347-200210000-00009","article-title":"Cytokeratins 7and 20, Dpc4, and MUC5AC in the distinction of metastatic mucinous carcinomas in the ovary fromprimary ovarian mucinous tumors: Dpc4 assists in identifying metastatic pancreatic carcinomas","volume":"21","author":"Ji","year":"2002","journal-title":"Int J Gynecol Pathol"},{"issue":"20","key":"key20260114113208_b13-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-021-01079-2","article-title":"Primary mucinous ovarian tumors vs. ovarian metastases from gastrointestinal tract, pancreas and biliary tree: A review of current problematics","volume":"16","author":"Dundr","year":"2021","journal-title":"Diagn Pathol"},{"key":"key20260114113208_b14-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"30","DOI":"10.4132\/jptm.2014.10.23","article-title":"Clinical and prognostic significances of cytokeratin 19 and KIT expression in surgically resectable pancreatic neuroendocrine tumors","volume":"49","author":"Son","year":"2015","journal-title":"J Pathol Transl Med"},{"key":"key20260114113208_b15-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1097\/01.pas.0000149708.12335.6a","article-title":"Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: Application of CDX2, CK17, MUC1, and MUC2","volume":"29","author":"Chu","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"key20260114113208_b16-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1111\/his.14555","article-title":"Concordance between core needle biopsy and surgical excision specimens for Ki-67 in breast cancer-a systematic review of the literature","volume":"80","author":"Kalvala","year":"2022","journal-title":"Histopathology"},{"key":"key20260114113208_b17-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.5858\/arpa.2012-0072-OA","article-title":"PAX2 and PAX8 expression in primary and metastatic renal tumors: A comprehensive comparison","volume":"136","author":"Ozcan","year":"2012","journal-title":"Arch Pathol Lab Med"},{"key":"key20260114113208_b18-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1001\/archsurg.1951.01250040726022","article-title":"Autoamputation in mucocele of the appendix","volume":"63","author":"Sachs","year":"1951","journal-title":"AMA Arch Surg"},{"key":"key20260114113208_b19-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1002\/jcu.22337","article-title":"Sonographically detected free appendicolith as a sign of retrocecal perforated appendicitis in a 2-year-old child","volume":"44","author":"Lovrenski","year":"2016","journal-title":"J Clin Ultrasound"},{"key":"key20260114113208_b20-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1177\/1093526616686256","article-title":"Autoamputation of the appendix presenting as a calcified abdominal mass following necrotizing enterocolitis","volume":"20","author":"Weil","year":"2017","journal-title":"Pediatr Dev Pathol"},{"issue":"6010568","key":"key20260114113208_b21-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/6010568","article-title":"Autoamputation of the appendix in a chronic adnexal abscess","volume":"2018","author":"Markey","year":"2018","journal-title":"Case Rep Obstet Gynecol"},{"issue":"192","key":"key20260114113208_b22-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-021-02747-z","article-title":"Floating appendix: Post-traumatic amputation of the appendix as sequela or complication?: A case report","volume":"15","author":"Sharma","year":"2021","journal-title":"J Med Case Rep"},{"key":"key20260114113208_b23-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.clcc.2018.11.007","article-title":"Review: Pathology and its clinical relevance of mucinous appendiceal neoplasms and pseudomyxoma peritonei","volume":"18","author":"Legu\u00e9","year":"2019","journal-title":"Clin Colorectal Cancer"},{"key":"key20260114113208_b24-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1046\/j.1365-2168.1998.00882.x","article-title":"Pseudomyxoma peritonei","volume":"85","author":"Hinson","year":"1998","journal-title":"Br J Surg"},{"key":"key20260114113208_b25-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.ejso.2007.04.002","article-title":"Appendiceal neoplasms and pseudomyxoma peritonei: A population based study","volume":"34","author":"Smeenk","year":"2008","journal-title":"Eur J Surg Oncol"},{"key":"key20260114113208_b26-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1097\/00000478-200308000-00006","article-title":"Appendiceal mucinous neoplasms: A clinicopathologic analysis of 107 cases","volume":"27","author":"Misdraji","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"key20260114113208_b27-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s00464-006-9005-y","article-title":"Comparison of therapeutic effectiveness of percutaneous drainage with antibiotics versus antibiotics alone in the treatment of periappendiceal abscess: Is appendectomy always necessary after perforation of appendix?","volume":"21","author":"Zerem","year":"2007","journal-title":"Surg Endosc"},{"key":"key20260114113208_b28-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1002\/bjs.8739","article-title":"Classification of and cytoreductive surgery for Low-grade appendiceal mucinous neoplasms","volume":"99","author":"McDonald","year":"2012","journal-title":"Br J Surg"},{"key":"key20260114113208_b29-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1097\/DCR.0000000000000719","article-title":"Histological subtype remains a significant prognostic factor for survival outcomes in patients with appendiceal mucinous neoplasm with peritoneal dissemination","volume":"60","author":"Huang","year":"2017","journal-title":"Dis Colon Rectum"},{"key":"key20260114113208_b30-ETM-31-2-13043","first-page":"256","article-title":"Clinical delivery system for intraperitoneal hyperthermic chemotherapy","volume":"40","author":"Spratt","year":"1980","journal-title":"Cancer Res"},{"key":"key20260114113208_b31-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1002\/jso.21478","article-title":"Pont hepatique (hepatic bridge), an important anatomic structure in cytoreductive surgery","volume":"101","author":"Sugarbaker","year":"2010","journal-title":"J Surg Oncol"},{"issue":"20190015","key":"key20260114113208_b32-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1515\/pp-2019-0015","article-title":"Impact of extent of parietal peritonectomy on oncological outcome after cytoreductive surgery and HIPEC","volume":"4","author":"Somashekhar","year":"2019","journal-title":"Pleura Peritoneum"},{"key":"key20260114113208_b33-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"6906","DOI":"10.3748\/wjg.v22.i30.6906","article-title":"Chinese expert consensus on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancies","volume":"22","author":"Li","year":"2016","journal-title":"World J Gastroenterol"},{"key":"key20260114113208_b34-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"68","DOI":"10.4251\/wjgo.v2.i2.68","article-title":"Hyperthermic intraperitoneal chemotherapy: Rationale and technique","volume":"2","author":"Gonzalez-Moreno","year":"2010","journal-title":"World J Gastrointest Oncol"},{"key":"key20260114113208_b35-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1245\/aso.2003.01.018","article-title":"Intraperitoneal chemohyperthermia using a closed abdominal procedure and cytoreductive surgery for the treatment of peritoneal carcinomatosis: Morbidity and mortality analysis of 216 consecutive procedures","volume":"10","author":"Glehen","year":"2003","journal-title":"Ann Surg Oncol"},{"key":"key20260114113208_b36-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1093\/annonc\/mdf019","article-title":"Heated intraoperative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis: Pharmacokinetics and tissue distribution","volume":"13","author":"Elias","year":"2002","journal-title":"Ann Oncol"},{"key":"key20260114113208_b37-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1593\/neo.03205","article-title":"A theoretical model for intraperitoneal delivery of cisplatin and the effect of hyperthermia on drug penetration distance","volume":"6","author":"El-Kareh","year":"2004","journal-title":"Neoplasia"},{"key":"key20260114113208_b38-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"S65","DOI":"10.1007\/s13193-018-00870-w","article-title":". Analysis of clinical outcomes of pseudomyxoma peritonei from appendicular origin following cytoreductive surgery and hyperthermic intraperitoneal Chemotherapy-A Retrospective study from INDEPSO","volume":"10 (Suppl 1)","author":"Sinukumar","year":"2019","journal-title":"Indian J Surg Oncol"},{"key":"key20260114113208_b39-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1007\/s00104-023-01937-3","article-title":"Surgical treatment of pseudomyxoma peritonei-Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy","volume":"94","author":"Wahba","year":"2023","journal-title":"Chirurgie (Heidelb)"},{"key":"key20260114113208_b40-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1245\/s10434-022-12367-6","article-title":"Relapse of pseudomyxoma peritonei after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Pattern of failure, clinical management and outcomes","volume":"30","author":"Baratti","year":"2023","journal-title":"Ann Surg Oncol"},{"issue":"e206363","key":"key20260114113208_b41-ETM-31-2-13043","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2020.6363","article-title":"The role of hyperthermic intraperitoneal chemotherapy in pseudomyxoma peritonei after cytoreductive surgery","volume":"156","author":"Kusamura","year":"2021","journal-title":"JAMA Surg"},{"key":"key20260114113208_b42-ETM-31-2-13043","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.ejso.2014.08.476","article-title":"Recurrence and outcome after complete tumour removal and hyperthermic intraperitoneal chemotherapy in 512 patients with pseudomyxoma peritonei from perforated appendiceal mucinous tumours","volume":"41","author":"Lord","year":"2015","journal-title":"Eur J Surg Oncol"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T09:32:12Z","timestamp":1768383132000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2025.13043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,5]]},"references-count":42,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,12,5]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2025.13043","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,5]]}}}