{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:53:06Z","timestamp":1791175986651,"version":"4.1.0"},"reference-count":91,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Ther Med"],"DOI":"10.3892\/etm.2026.13312","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:13:24Z","timestamp":1790140404000},"page":"1-19","source":"Crossref","is-referenced-by-count":0,"title":["Integrated bioinformatics and clinical validation of oxidative stress\u2011associated genes in atrial fibrillation and chronic kidney disease"],"prefix":"10.3892","volume":"32","author":[{"given":"Jiyi","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116001, P.R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zezhou","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengzhi","family":"Sun","sequence":"additional","affiliation":[{"name":"Heart Centre, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Heart Centre, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunbo","family":"Ba","sequence":"additional","affiliation":[{"name":"Heart Centre, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomeng","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Heart Centre, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"key20261005073525_b1-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2824","DOI":"10.1093\/eurheartj\/ehab301","article-title":"Atrial fibrillation and chronic kidney disease","volume":"42","author":"Benn","year":"2021","journal-title":"Eur Heart J"},{"key":"key20261005073525_b2-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.ccep.2020.11.001","article-title":"Renal disease and atrial fibrillation","volume":"13","author":"Stefil","year":"2021","journal-title":"Card Electrophysiol Clin"},{"key":"key20261005073525_b3-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1093\/europace\/euu040","article-title":"Antioxidants for prevention of atrial fibrillation: a potentially useful future therapeutic approach? A review of the literature and meta-analysis","volume":"16","author":"Violi","year":"2014","journal-title":"Europace"},{"key":"key20261005073525_b4-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1007\/s00467-018-4005-4","article-title":"Oxidative stress in chronic kidney disease","volume":"34","author":"Daenen","year":"2019","journal-title":"Pediatr Nephrol"},{"issue":"143","key":"key20261005073525_b5-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2504143","article-title":"Atrial fibrillation and chronic kidney disease: Aetiology and management","volume":"25","author":"Sidhu","year":"2024","journal-title":"Rev Cardiovasc Med"},{"key":"key20261005073525_b6-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.kint.2024.01.033","article-title":"Inflammasome activation: Unraveling the link between chronic kidney disease and atrial fibrillation","volume":"106","author":"Sahinoz","year":"2024","journal-title":"Kidney Int"},{"issue":"5516185","key":"key20261005073525_b7-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5516185","article-title":"Molecular signatures of human chronic atrial fibrillation in primary mitral regurgitation","volume":"2021","author":"\u00c7ubuk\u00e7uo\u011flu Deniz","year":"2021","journal-title":"Cardiovasc Ther"},{"issue":"23","key":"key20261005073525_b8-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1186\/1755-8794-6-23","article-title":"Alteration of human blood cell transcriptome in uremia","volume":"6","author":"Scherer","year":"2013","journal-title":"BMC Med Genomics"},{"key":"key20261005073525_b9-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.hrthm.2012.11.013","article-title":"Region-specific gene expression profiles in the left atria of patients with valvular atrial fibrillation","volume":"10","author":"Yeh","year":"2013","journal-title":"Heart Rhythm"},{"key":"key20261005073525_b10-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.jacc.2009.08.064","article-title":"Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation","volume":"55","author":"Adam","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"1713","key":"key20261005073525_b11-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37450-8","article-title":"Neuraminidase 1 promotes renal fibrosis development in male mice","volume":"14","author":"Chen","year":"2023","journal-title":"Nat Commun"},{"key":"key20261005073525_b12-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1007\/s11255-018-1892-z","article-title":"Transcriptome analysis supports viral infection and fluoride toxicity as contributors to chronic kidney disease of unknown etiology (CKDu) in Sri Lanka","volume":"50","author":"Sayanthooran","year":"2018","journal-title":"Int Urol Nephrol"},{"issue":"e47","key":"key20261005073525_b13-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"key20261005073525_b14-ETM-32-5-13312","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/wics.147","article-title":"ggplot2","volume":"3","author":"Wickham","year":"2011","journal-title":"Wiley Interdiscip Rev Comput Stat"},{"key":"key20261005073525_b15-ETM-32-5-13312","author":"Kolde"},{"issue":"1397498","key":"key20261005073525_b16-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1397498","article-title":"Mechanism of isorhynchophylline in lipopolysaccharide-induced acute lung injury based on proteomic technology","volume":"15","author":"Li","year":"2024","journal-title":"Front Pharmacol"},{"key":"key20261005073525_b17-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: A software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"key20261005073525_b18-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"D419","DOI":"10.1093\/nar\/gky1038","article-title":"PANTHER version 14: More genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools","volume":"47","author":"Mi","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"key20261005073525_b19-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key20261005073525_b20-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: An R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"issue":"100141","key":"key20261005073525_b21-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1016\/j.xinn.2021.100141","article-title":"clusterProfiler 4.0: A universal enrichment tool for interpreting omics data","volume":"2","author":"Wu","year":"2021","journal-title":"Innovation (Camb)"},{"key":"key20261005073525_b22-ETM-32-5-13312","author":"Meyer"},{"key":"key20261005073525_b23-ETM-32-5-13312","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s40484-017-0121-6","article-title":"Variable importance-weighted Random Forests","volume":"5","author":"Liu","year":"2017","journal-title":"Quant Biol"},{"issue":"77","key":"key20261005073525_b24-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-77","article-title":"pROC: An open-source package for R and S+ to analyze and compare ROC curves","volume":"12","author":"Robin","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"key20261005073525_b25-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1002\/cac2.12067","article-title":"A nomogram for predicting overall survival in patients with low-grade endometrial stromal sarcoma: A population-based analysis","volume":"40","author":"Wu","year":"2020","journal-title":"Cancer Commun (Lond)"},{"key":"key20261005073525_b26-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nmeth.3337","article-title":"Robust enumeration of cell subsets from tissue expression profiles","volume":"12","author":"Newman","year":"2015","journal-title":"Nat Methods"},{"key":"key20261005073525_b27-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"D174","DOI":"10.1093\/nar\/gkad1059","article-title":"JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles","volume":"52","author":"Rauluseviciute","year":"2024","journal-title":"Nucleic Acids Res"},{"key":"key20261005073525_b28-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"D108","DOI":"10.1093\/nar\/gkj143","article-title":"TRANSFAC and its module TRANSCompel: Transcriptional gene regulation in eukaryotes","volume":"34(Database issue)","author":"Matys","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"key20261005073525_b29-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20261005073525_b30-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.ijcard.2018.11.098","article-title":"Comparison of atrial fibrillation in CKD and non-CKD populations: A cross-sectional analysis from the kailuan study","volume":"277","author":"Guo","year":"2019","journal-title":"Int J Cardiol"},{"key":"key20261005073525_b31-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1056\/NEJMoa1105594","article-title":"Stroke and bleeding in atrial fibrillation with chronic kidney disease","volume":"367","author":"Olesen","year":"2012","journal-title":"N Engl J Med"},{"key":"key20261005073525_b32-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1038\/s41581-024-00889-z","article-title":"Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease","volume":"21","author":"Miguel","year":"2025","journal-title":"Nat Rev Nephrol"},{"key":"key20261005073525_b33-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41569-022-00759-w","article-title":"Inflammatory signalling in atrial cardiomyocytes: A novel unifying principle in atrial fibrillation pathophysiology","volume":"20","author":"Dobrev","year":"2023","journal-title":"Nat Rev Cardiol"},{"issue":"1726","key":"key20261005073525_b34-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01726","article-title":"Chronic kidney disease increases atrial fibrillation inducibility: Involvement of inflammation, atrial fibrosis, and connexins","volume":"9","author":"Qiu","year":"2018","journal-title":"Front Physiol"},{"key":"key20261005073525_b35-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.ijcard.2009.03.110","article-title":"Atrial fibrosis and atrial fibrillation: The role of the TGF-\u03b21 signaling pathway","volume":"143","author":"Gramley","year":"2010","journal-title":"Int J Cardiol"},{"issue":"673002","key":"key20261005073525_b36-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.673002","article-title":"Linking oxidative stress and DNA damage to changes in the expression of extracellular matrix components","volume":"12","author":"Martins","year":"2021","journal-title":"Front Genet"},{"key":"key20261005073525_b37-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1038\/s44320-025-00116-2","article-title":"Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression","volume":"21","author":"Tuechler","year":"2025","journal-title":"Mol Syst Biol"},{"key":"key20261005073525_b38-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1159\/000334434","article-title":"Atrial remodeling in atrial fibrillation and some related microRNAs","volume":"120","author":"Sharma","year":"2011","journal-title":"Cardiology"},{"issue":"123836","key":"key20261005073525_b39-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2025.123836","article-title":"From AKI to CKD: Role of miRNAs in disease progression","volume":"378","author":"Carneiro-Ramos","year":"2025","journal-title":"Life Sci"},{"issue":"162","key":"key20261005073525_b40-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2018.00162","article-title":"Identification of central regulators of calcium signaling and ECM-Receptor interaction genetically associated with the progression and recurrence of atrial fibrillation","volume":"9","author":"B\u00fcttner","year":"2018","journal-title":"Front Genet"},{"key":"key20261005073525_b41-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"3200","DOI":"10.1016\/j.ijcard.2013.04.113","article-title":"Focal adhesion kinase mediates atrial fibrosis via the AKT\/S6K signaling pathway in chronic atrial fibrillation patients with rheumatic mitral valve disease","volume":"168","author":"Zhang","year":"2013","journal-title":"Int J Cardiol"},{"issue":"627800","key":"key20261005073525_b42-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.627800","article-title":"Integrin, exosome and kidney disease","volume":"11","author":"Shen","year":"2020","journal-title":"Front Physiol"},{"key":"key20261005073525_b43-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/s0002-9440(10)63326-3","article-title":"Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury","volume":"165","author":"Chen","year":"2004","journal-title":"Am J Pathol"},{"key":"key20261005073525_b44-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1289\/ehp.8026","article-title":"Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence","volume":"114","author":"Zhou","year":"2006","journal-title":"Environ Health Perspect"},{"key":"key20261005073525_b45-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1007\/s00018-020-03552-5","article-title":"Ubiquitin chromatin remodelling after DNA damage is associated with the expression of key cancer genes and pathways","volume":"78","author":"Cole","year":"2021","journal-title":"Cell Mol Life Sci"},{"issue":"28592","key":"key20261005073525_b46-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1038\/srep28592","article-title":"Btg2 is a negative regulator of cardiomyocyte hypertrophy through a decrease in cytosolic RNA","volume":"6","author":"Masumura","year":"2016","journal-title":"Sci Rep"},{"issue":"e2304360","key":"key20261005073525_b47-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202304360","article-title":"Btg2 promotes focal segmental glomerulosclerosis via Smad3-dependent podocyte-mesenchymal transition","volume":"10","author":"Dan Hu","year":"2023","journal-title":"Adv Sci (Weinh)"},{"issue":"152","key":"key20261005073525_b48-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-024-01915-6","article-title":"Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease","volume":"17","author":"Pan","year":"2024","journal-title":"BMC Med Genomics"},{"issue":"R12","key":"key20261005073525_b49-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2014-15-1-r12","article-title":"Global target mRNA specification and regulation by the RNA-binding protein ZFP36","volume":"15","author":"Mukherjee","year":"2014","journal-title":"Genome Biol"},{"key":"key20261005073525_b50-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"161","DOI":"10.4161\/epi.26931","article-title":"Massive analysis of cDNA Ends (MACE) and miRNA expression profiling identifies proatherogenic pathways in chronic kidney disease","volume":"9","author":"Zawada","year":"2014","journal-title":"Epigenetics"},{"key":"key20261005073525_b51-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1161\/ATVBAHA.113.301496","article-title":"mRNA-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in aortic endothelial cells","volume":"33","author":"Zhang","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key20261005073525_b52-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2213","DOI":"10.1681\/ASN.2013091023","article-title":"Hypertonicity compromises renal mineralocorticoid receptor signaling through Tis11b-mediated post-transcriptional control","volume":"25","author":"Viengchareun","year":"2014","journal-title":"J Am Soc Nephrol"},{"issue":"110708","key":"key20261005073525_b53-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2023.110708","article-title":"Donor white blood cell differential is the single largest determinant of whole blood gene expression patterns","volume":"115","author":"O'Connell","year":"2023","journal-title":"Genomics"},{"key":"key20261005073525_b54-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"H667","DOI":"10.1152\/ajpheart.00746.2015","article-title":"Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure","volume":"310","author":"Hamilton","year":"2016","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"e13567","key":"key20261005073525_b55-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1111\/apha.13567","article-title":"Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5-cryab-hspb2 signalling in zebrafish","volume":"231","author":"Gou","year":"2021","journal-title":"Acta Physiol (Oxf)"},{"issue":"64","key":"key20261005073525_b56-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-025-01876-2","article-title":"Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure","volume":"17","author":"Guo","year":"2025","journal-title":"Clin Epigenetics"},{"key":"key20261005073525_b57-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1161\/CIRCRESAHA.122.320781","article-title":"Inhibition of Fap promotes cardiac repair by stabilizing BNP","volume":"132","author":"Sun","year":"2023","journal-title":"Circ Res"},{"key":"key20261005073525_b58-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1093\/cvr\/cvae224","article-title":"Interleukin 11 therapy causes acute left ventricular dysfunction","volume":"120","author":"Sweeney","year":"2024","journal-title":"Cardiovasc Res"},{"issue":"1059","key":"key20261005073525_b59-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3390\/antiox14091059","article-title":"Peroxisome proliferator-activated receptor family of lipid-activated nuclear receptors alpha silencing promotes oxidative stress and hypertrophic phenotype in rat cardiac cells","volume":"14","author":"Bianchi","year":"2025","journal-title":"Antioxidants (Basel)"},{"key":"key20261005073525_b60-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1007\/s12033-023-00845-5","article-title":"the gene network correlation analysis of obesity to type 1 diabetes and cardiovascular disorders: An interactome-based bioinformatics approach","volume":"66","author":"D'Souza","year":"2024","journal-title":"Mol Biotechnol"},{"key":"key20261005073525_b61-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1093\/procel\/pwaf072","article-title":"Systematic analyses uncover plasma proteins linked to incident cardiovascular diseases","volume":"17","author":"Chen","year":"2026","journal-title":"Protein Cell"},{"issue":"1260419","key":"key20261005073525_b62-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260419","article-title":"Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"issue":"1406","key":"key20261005073525_b63-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12091406","article-title":"A differential profile of biomarkers between patients with atrial fibrillation and healthy controls","volume":"12","author":"Merino-Merino","year":"2022","journal-title":"J Pers Med"},{"key":"key20261005073525_b64-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.3390\/ijms16022320","article-title":"Cyclic nucleotide signalling in kidney fibrosis","volume":"16","author":"Schinner","year":"2015","journal-title":"Int J Mol Sci"},{"key":"key20261005073525_b65-ETM-32-5-13312","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1139\/y01-052","article-title":"Brain natriuretic peptide appears to act locally as an antifibrotic factor in the heart","volume":"79","author":"Ogawa","year":"2001","journal-title":"Can J Physiol Pharmacol"},{"key":"key20261005073525_b66-ETM-32-5-13312","first-page":"135","article-title":"Changes in brain natriuretic peptide level as a predictor of AF recurrence after electrical cardioversion","volume":"59","author":"Ruggiero","year":"2011","journal-title":"Minerva Cardioangiol"},{"key":"key20261005073525_b67-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1016\/j.ekir.2021.01.006","article-title":"N-terminal pro-B-type natriuretic peptide and incident CKD","volume":"6","author":"Sasaki","year":"2021","journal-title":"Kidney Int Rep"},{"key":"key20261005073525_b68-ETM-32-5-13312","first-page":"136","article-title":"Cardiac biomarker NTproBNP in chronic kidney disease - a brief review","volume":"22","author":"Nechita","year":"2015","journal-title":"Mod Med"},{"key":"key20261005073525_b69-ETM-32-5-13312","doi-asserted-by":"crossref","first-page":"823","DOI":"10.3760\/cma.j.issn.0366-6999.20122497","article-title":"Brain natriuretic peptide and copeptin levels are associated with cardiovascular disease in patients with chronic kidney disease","volume":"126","author":"Li","year":"2013","journal-title":"Chin Med J (Engl)"},{"key":"key20261005073525_b70-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1124\/jpet.116.234591","article-title":"Class I histone deacetylase inhibition for the treatment of sustained atrial fibrillation","volume":"358","author":"Seki","year":"2016","journal-title":"J Pharmacol Exp Ther"},{"key":"key20261005073525_b71-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.trsl.2018.06.002","article-title":"Histone deacetylase inhibition attenuates atrial arrhythmogenesis in sterile pericarditis","volume":"200","author":"Chang","year":"2018","journal-title":"Transl Res"},{"key":"key20261005073525_b72-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1016\/j.ijcard.2014.09.175","article-title":"Histone deacetylase inhibition reduces pulmonary vein arrhythmogenesis through calcium regulation","volume":"177","author":"Lkhagva","year":"2014","journal-title":"Int J Cardiol"},{"key":"key20261005073525_b73-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1161\/CIRCULATIONAHA.120.046462","article-title":"HDAC inhibition reverses preexisting diastolic dysfunction and blocks covert extracellular matrix remodeling","volume":"143","author":"Travers","year":"2021","journal-title":"Circulation"},{"key":"key20261005073525_b74-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1159\/000505295","article-title":"Application of histone deacetylase inhibitors in renal interstitial fibrosis","volume":"6","author":"Nie","year":"2020","journal-title":"Kidney Dis (Basel)"},{"issue":"121","key":"key20261005073525_b75-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2015.00121","article-title":"Treatment of chronic kidney diseases with histone deacetylase inhibitors","volume":"6","author":"Liu","year":"2015","journal-title":"Front Physiol"},{"key":"key20261005073525_b76-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.jare.2024.07.026","article-title":"Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis","volume":"72","author":"Chen","year":"2025","journal-title":"J Adv Res"},{"key":"key20261005073525_b77-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/nm1468","article-title":"Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis","volume":"12","author":"Rossi","year":"2006","journal-title":"Nat Med"},{"issue":"279","key":"key20261005073525_b78-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01497-2","article-title":"Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression","volume":"8","author":"He","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"e0307466","key":"key20261005073525_b79-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0307466","article-title":"Neutrophil-percentage-to-albumin ratio is associated with chronic kidney disease: Evidence from NHANES 2009-2018","volume":"19","author":"Li","year":"2024","journal-title":"PLoS One"},{"key":"key20261005073525_b80-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"731","DOI":"10.3760\/cma.j.cn121090-20240924-00367","article-title":"Clinical characteristics and survival outcomes of patients with immunoglobulin A multiple myeloma in the bortezomib era: A single-center retrospective cohort study","volume":"46","author":"Gao","year":"2025","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"key":"key20261005073525_b81-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.kint.2024.04.016","article-title":"The glycolytic enzyme PFKFB3 drives kidney fibrosis through promoting histone lactylation-mediated NF-\u03baB family activation","volume":"106","author":"Wang","year":"2024","journal-title":"Kidney Int"},{"issue":"e0312696","key":"key20261005073525_b82-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0312696","article-title":"Molecular characterization of PANoptosis-related genes in chronic kidney disease","volume":"19","author":"Zhang","year":"2024","journal-title":"PLoS One"},{"issue":"1551423","key":"key20261005073525_b83-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1551423","article-title":"Homotherapy for heteropathy of chronic kidney disease and oligoasthenozoospermia through regulating SIRT1\/NF-\u03baB pathway by Shenqi pills","volume":"16","author":"Huang","year":"2025","journal-title":"Front Pharmacol"},{"issue":"816","key":"key20261005073525_b84-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06347-1","article-title":"Inhibition of PFKP in renal tubular epithelial cell restrains TGF-\u03b2 induced glycolysis and renal fibrosis","volume":"14","author":"Yang","year":"2023","journal-title":"Cell Death Dis"},{"issue":"361","key":"key20261005073525_b85-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11020361","article-title":"Uremic toxin indoxyl sulfate impairs hydrogen sulfide formation in renal tubular cells","volume":"11","author":"Lu","year":"2022","journal-title":"Antioxidants (Basel)"},{"issue":"e37366","key":"key20261005073525_b86-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e37366","article-title":"Identification of senescence-related genes for potential therapeutic biomarkers of atrial fibrillation by bioinformatics, human histological validation, and molecular docking","volume":"10","author":"Liu","year":"2024","journal-title":"Heliyon"},{"issue":"1647275","key":"key20261005073525_b87-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2025.1647275","article-title":"Integrated bioinformatic analysis reveals the underlying mitochondria-associated endoplasmic reticulum membranes-related biomarkers for atrial fibrillation","volume":"16","author":"Wang","year":"2025","journal-title":"Front Physiol"},{"key":"key20261005073525_b88-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1182\/blood.2022017235","article-title":"How I use genomics and BTK inhibitors in the treatment of Waldenstr\u00f6m macroglobulinemia","volume":"143","author":"Treon","year":"2024","journal-title":"Blood"},{"key":"key20261005073525_b89-ETM-32-5-13312","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.kint.2023.10.022","article-title":"Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury and prevents transition to chronic kidney disease","volume":"105","author":"Beamish","year":"2024","journal-title":"Kidney Int"},{"issue":"7290","key":"key20261005073525_b90-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-62319-3","article-title":"Exome analysis links kidney malformations to developmental disorders and reveals causal genes","volume":"16","author":"Milo Rasouly","year":"2025","journal-title":"Nat Commun"},{"issue":"1567310","key":"key20261005073525_b91-ETM-32-5-13312","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2025.1567310","article-title":"Comprehensive analysis of lactylation-related gene and immune microenvironment in atrial fibrillation","volume":"12","author":"Ma","year":"2025","journal-title":"Front Cardiovasc Med"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:35:33Z","timestamp":1791174933000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/etm.2026.13312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":91,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,9,23]]}},"URL":"https:\/\/doi.org\/10.3892\/etm.2026.13312","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]}}}