{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:28:29Z","timestamp":1790940509932,"version":"4.1.0"},"reference-count":45,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.3892\/ijmm.2013.1381","type":"journal-article","created":{"date-parts":[[2013,5,14]],"date-time":"2013-05-14T07:03:37Z","timestamp":1368515017000},"page":"219-226","source":"Crossref","is-referenced-by-count":38,"title":["Differential expression of miRNAs in the nervous system of a rat model of bilateral sciatic nerve chronic constriction injury"],"prefix":"10.3892","volume":"32","author":[{"given":"HAIXIA","family":"LI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LE","family":"SHEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHAO","family":"MA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YUGUANG","family":"HUANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2013,5,14]]},"reference":[{"key":"key20180107230110_b1-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1212\/01.wnl.0000282763.29778.59","article-title":"Neuropathic pain: redefinition and a grading system for clinical and research purposes","volume":"70","author":"Treede","year":"2008","journal-title":"Neurology"},{"key":"key20180107230110_b2-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.pain.2010.07.031","article-title":"NeuPSIG guidelines on neuropathic pain assessment","volume":"152","author":"Haanp\u00e4\u00e4","year":"2011","journal-title":"Pain"},{"key":"key20180107230110_b3-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mpaic.2010.10.010","article-title":"Assessment of acute and chronic pain","volume":"12","author":"Green","year":"2011","journal-title":"Anaesth Intensive Care Med"},{"key":"key20180107230110_b4-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejphar.2010.11.027","article-title":"Increased synaptic GluR1 subunits in the anterior cingulate cortex of rats with peripheral inflammation","volume":"653","author":"Bie","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"key20180107230110_b5-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.pain.2010.12.014","article-title":"Calcium channel alpha-2-delta-1 protein upregulation in dorsal spinal cord mediates spinal cord injury-induced neuropathic pain states","volume":"152","author":"Boroujerdi","year":"2011","journal-title":"Pain"},{"key":"key20180107230110_b6-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.brainres.2011.01.006","article-title":"Peripheral nerve injury alters the expression of NF-kappaB in the rat\u2019s hippocampus","volume":"1378","author":"Chou","year":"2011","journal-title":"Brain Res"},{"key":"key20180107230110_b7-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1126\/science.1206243","article-title":"HCN2 ion channels play a central role in inflammatory and neuropathic pain","volume":"333","author":"Emery","year":"2011","journal-title":"Science"},{"key":"key20180107230110_b8-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.brainres.2011.01.002","article-title":"Role of different brain areas in peripheral nerve injury-induced neuropathic pain","volume":"1381","author":"Jaggi","year":"2011","journal-title":"Brain Res"},{"key":"key20180107230110_b9-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/nrn1704","article-title":"Pain and emotion interactions in subregions of the cingulate gyrus","volume":"6","author":"Vogt","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"key20180107230110_b10-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.neuroscience.2011.12.045","article-title":"Dorsal root ganglia isolated from Nf1+\/\u2212 mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels","volume":"206","author":"Hodgdon","year":"2012","journal-title":"Neuroscience"},{"key":"key20180107230110_b11-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.pain.2009.02.006","article-title":"Profiling of dynamically changed gene expression in dorsal root ganglia post peripheral nerve injury and a critical role of injury-induced glial fibrillary acetic protein in maintenance of pain behaviors","volume":"143","author":"Kim","year":"2009","journal-title":"Pain"},{"key":"key20180107230110_b12-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1744-8069-7-94","article-title":"Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization","volume":"7","author":"Cady","year":"2011","journal-title":"Mol Pain"},{"key":"key20180107230110_b13-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1523\/JNEUROSCI.5541-09.2010","article-title":"Epigenetic gene silencing underlies C-fiber dysfunctions in neuropathic pain","volume":"30","author":"Uchida","year":"2010","journal-title":"J Neurosci"},{"key":"key20180107230110_b14-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.neuroscience.2009.08.033","article-title":"Changes in expression of sensory organ-specific microRNAs in rat dorsal root ganglia in association with mechanical hyper-sensitivity induced by spinal nerve ligation","volume":"164","author":"Aldrich","year":"2009","journal-title":"Neuroscience"},{"key":"key20180107230110_b15-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1261\/rna.783108","article-title":"MicroRNA expression in the adult mouse central nervous system","volume":"14","author":"Bak","year":"2008","journal-title":"RNA"},{"key":"key20180107230110_b16-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00418-010-0772-0","article-title":"Differential expression of microRNA-1 in dorsal root ganglion neurons","volume":"135","author":"Bastian","year":"2010","journal-title":"Histochem Cell Biol"},{"key":"key20180107230110_b17-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"e17670","DOI":"10.1371\/journal.pone.0017670","article-title":"Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain","volume":"6","author":"von Schack","year":"2011","journal-title":"PLoS One"},{"key":"key20180107230110_b18-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1101\/gad.1884710","article-title":"Mammalian microRNAs: experimental evaluation of novel and previously annotated genes","volume":"24","author":"Chiang","year":"2010","journal-title":"Genes Dev"},{"key":"key20180107230110_b19-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/1471-2164-10-214","article-title":"Identification and target prediction of miRNAs specifically expressed in rat neural tissue","volume":"10","author":"Hua","year":"2009","journal-title":"BMC Genomics"},{"key":"key20180107230110_b20-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/nrn2037","article-title":"The neuronal microRNA system","volume":"7","author":"Kosik","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"key20180107230110_b21-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/j.febslet.2006.03.019","article-title":"Identification of new central nervous system specific mouse microRNAs","volume":"580","author":"Wheeler","year":"2006","journal-title":"FEBS Lett"},{"key":"key20180107230110_b22-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1744-8069-7-17","article-title":"Differential expression of microRNAs in mouse pain models","volume":"7","author":"Kusuda","year":"2011","journal-title":"Mol Pain"},{"key":"key20180107230110_b23-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jchemneu.2011.01.005","article-title":"MicroRNAs in Parkinson\u2019s disease","volume":"42","author":"Harraz","year":"2011","journal-title":"J Chem Neuroanat"},{"key":"key20180107230110_b24-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.brainres.2011.01.067","article-title":"MicroRNAs 144, 145, and 214 are down-regulated in primary neurons responding to sciatic nerve transection","volume":"1383","author":"Zhang","year":"2011","journal-title":"Brain Res"},{"key":"key20180107230110_b25-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1744-8069-6-7","article-title":"Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli","volume":"6","author":"Datta","year":"2010","journal-title":"Mol Pain"},{"key":"key20180107230110_b26-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.jpain.2005.03.003","article-title":"Bilateral chronic constriction of the sciatic nerve: a model of long-term cold hyper-algesia","volume":"6","author":"Vierck","year":"2005","journal-title":"J Pain"},{"key":"key20180107230110_b27-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J Neurosci Methods"},{"key":"key20180107230110_b28-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat Protoc"},{"key":"key20180107230110_b29-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1261\/rna.5980303","article-title":"A microRNA array reveals extensive regulation of microRNAs during brain development","volume":"9","author":"Krichevsky","year":"2003","journal-title":"RNA"},{"key":"key20180107230110_b30-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/nature02871","article-title":"The functions of animal microRNAs","volume":"431","author":"Ambros","year":"2004","journal-title":"Nature"},{"key":"key20180107230110_b31-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/nature04367","article-title":"A brain-specific microRNA regulates dendritic spine development","volume":"439","author":"Schratt","year":"2006","journal-title":"Nature"},{"key":"key20180107230110_b32-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.gene.2012.01.057","article-title":"Aberrant brain microRNA target and miRISC gene expression in the anx\/anx anorexia mouse model","volume":"497","author":"Mercader","year":"2012","journal-title":"Gene"},{"key":"key20180107230110_b33-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/j.1600-6143.2011.03958.x","article-title":"Differential expression of microRNAs during allograft rejection","volume":"12","author":"Wei","year":"2012","journal-title":"Am J Transplant"},{"key":"key20180107230110_b34-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nm.2584","article-title":"MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy","volume":"18","author":"Liu","year":"2012","journal-title":"Nat Med"},{"key":"key20180107230110_b35-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1073\/pnas.0805854106","article-title":"MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction","volume":"106","author":"Kocerha","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180107230110_b36-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"10860","DOI":"10.1523\/JNEUROSCI.1980-10.2010","article-title":"Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds","volume":"30","author":"Zhao","year":"2010","journal-title":"J Neurosci"},{"key":"key20180107230110_b37-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/nm.2231","article-title":"Central mechanisms of pathological pain","volume":"16","author":"Kuner","year":"2010","journal-title":"Nature Med"},{"key":"key20180107230110_b38-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1038\/nm.2235","article-title":"Nociceptor sensitization in pain pathogenesis","volume":"16","author":"Gold","year":"2010","journal-title":"Nature Med"},{"key":"key20180107230110_b39-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"39836","DOI":"10.1074\/jbc.M111.261701","article-title":"Relationship of axonal voltage-gated sodium channel 1.8 (NaV1.8) mRNA accumulation to sciatic nerve injury-induced painful neuropathy in rats","volume":"286","author":"Ruangsri","year":"2011","journal-title":"J Biol Chem"},{"key":"key20180107230110_b40-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.neuroscience.2011.07.031","article-title":"Different expression of tissue inhibitor of metalloproteinase family members in rat dorsal root ganglia and their changes after peripheral nerve injury","volume":"193","author":"Huang","year":"2011","journal-title":"Neuroscience"},{"key":"key20180107230110_b41-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.mrgentox.2010.05.007","article-title":"Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model","volume":"722","author":"Koturbash","year":"2011","journal-title":"Mutat Res"},{"key":"key20180107230110_b42-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1101\/gad1367806","article-title":"Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis","volume":"20","author":"Rao","year":"2006","journal-title":"Genes Dev"},{"key":"key20180107230110_b43-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/j.1742-4658.2010.07997.x","article-title":"microRNA-203 suppresses bladder cancer development by repressing bcl-w expression","volume":"278","author":"Bo","year":"2011","journal-title":"FEBS J"},{"key":"key20180107230110_b44-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/nature06783","article-title":"LNA-mediated microRNA silencing in non-human primates","volume":"452","author":"Elm\u00e9n","year":"2008","journal-title":"Nature"},{"key":"key20180107230110_b45-ijmm-32-01-0219","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/gt.2011.50","article-title":"MicroRNA therapeutics","volume":"18","author":"Broderick","year":"2011","journal-title":"Gene Ther"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ijmm.2013.1381\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T23:13:09Z","timestamp":1515366789000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2013.1381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,14]]},"references-count":45,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,5,14]]},"published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.3892\/ijmm.2013.1381"],"URL":"https:\/\/doi.org\/10.3892\/ijmm.2013.1381","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,14]]}}}