{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:19:04Z","timestamp":1790234344375,"version":"4.1.0"},"reference-count":41,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.3892\/ijmm.2013.1495","type":"journal-article","created":{"date-parts":[[2013,9,13]],"date-time":"2013-09-13T10:14:23Z","timestamp":1379067263000},"page":"1204-1214","source":"Crossref","is-referenced-by-count":6,"title":["Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis"],"prefix":"10.3892","volume":"32","author":[{"given":"BO","family":"GAO","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WANG","family":"SUN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XIANQI","family":"WANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XU","family":"JIA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BIAO","family":"MA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YU","family":"CHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WEIHUI","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DONGBO","family":"XUE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2013,9,13]]},"reference":[{"key":"key20180107225952_b1-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.cgh.2009.02.021","article-title":"Incidence, prevalence and clinical significance of abnormal hematological indices in compensated cirrhosis","volume":"7","author":"Qamar","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key20180107225952_b2-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1155\/2009\/591317","article-title":"Abnormal hematological indices in cirrhosis","volume":"23","author":"Qamar","year":"2009","journal-title":"Can J Gastroenterol"},{"key":"key20180107225952_b3-ijmm-32-05-1204","first-page":"1131","article-title":"The role of thrombopoietin in the thrombocytopenia of patients with live cirrhosis","volume":"100","author":"Rois","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"key20180107225952_b4-ijmm-32-05-1204","first-page":"72","article-title":"The anemia of cirrhosis","volume":"56","author":"Sheehy","year":"1960","journal-title":"J Lab Clin Med"},{"key":"key20180107225952_b5-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1172\/JCI105079","article-title":"Suppression of hematopoiesis by ethanol","volume":"43","author":"Sullivan","year":"1964","journal-title":"J Clin Invest"},{"key":"key20180107225952_b6-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0268-960X(91)90037-D","article-title":"Viruses and bone marrow failure","volume":"5","author":"Rosenfeld","year":"1991","journal-title":"Blood Rev"},{"key":"key20180107225952_b7-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s10620-009-0785-5","article-title":"Alterations of bone marrow sinusoidal endothelium in rat and patients with liver cirrhosis","volume":"55","author":"Zhao","year":"2010","journal-title":"Dig Dis Sci"},{"key":"key20180107225952_b8-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1152\/physiol.00025.2005","article-title":"The bone marrow vascular niche: home of HSC differentiation and mobilization","volume":"20","author":"Kopp","year":"2005","journal-title":"Physiology"},{"key":"key20180107225952_b9-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1182\/blood.V84.1.10.10","article-title":"Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion","volume":"84","author":"Rafii","year":"1994","journal-title":"Blood"},{"key":"key20180107225952_b10-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1006\/cyto.1999.0678","article-title":"Positive and negative haematopoietic cytokines produced by bone marrow endothelial cells","volume":"12","author":"Li","year":"2000","journal-title":"Cytokine"},{"key":"key20180107225952_b11-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S1074-7613(94)80014-6","article-title":"Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system","volume":"1","author":"Bernad","year":"1994","journal-title":"Immunity"},{"key":"key20180107225952_b12-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1038\/sj.leu.2401514","article-title":"Hematopoietic, immunomodulatory and epithelial effects of interleukin-11","volume":"13","author":"Schwertschlag","year":"1999","journal-title":"Leukemia"},{"key":"key20180107225952_b13-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1182\/blood.V88.1.82.82","article-title":"Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells","volume":"88","author":"Sitnicka","year":"1996","journal-title":"Blood"},{"key":"key20180107225952_b14-ijmm-32-05-1204","first-page":"943","article-title":"In vitro effects of GM-CSF on mature peripheral blood neutrophils","volume":"1","author":"Fossati","year":"1998","journal-title":"Int J Mol Med"},{"key":"key20180107225952_b15-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1093\/ndt\/gfr656","article-title":"Uraemia disrupts the vascular niche in a 3D co-culture system of human mesenchymal stem cells and endothelial cells","volume":"27","author":"Kramann","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"key20180107225952_b16-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"7124","DOI":"10.1158\/0008-5472.CAN-07-0686","article-title":"IFN-beta signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesench-ymal progenitors","volume":"67","author":"Tjandra","year":"2007","journal-title":"Cancer Res"},{"key":"key20180107225952_b17-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20180107225952_b18-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1172\/JCI24282","article-title":"Liver fibrosis","volume":"115","author":"Bataller","year":"2005","journal-title":"J Clin Invest"},{"key":"key20180107225952_b19-ijmm-32-05-1204","first-page":"229","article-title":"The role of humoral splenic factors in the formation and release of blood cells","volume":"2","author":"Ruhenstroth-Bauer","year":"1965","journal-title":"Semin Hematol"},{"key":"key20180107225952_b20-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1182\/blood.V88.9.3259.bloodjournal8893259","article-title":"Selectins and their ligands: current concepts and controversies","volume":"88","author":"Kansas","year":"1996","journal-title":"Blood"},{"key":"key20180107225952_b21-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1182\/blood-2008-01-078204","article-title":"The vessel wall and its interactions","volume":"111","author":"Wagner","year":"2008","journal-title":"Blood"},{"key":"key20180107225952_b22-ijmm-32-05-1204","first-page":"41","article-title":"Isolation and culture of human bone marrow endothelial cells","volume":"23","author":"Schweitzer","year":"1995","journal-title":"Exp Hematol"},{"key":"key20180107225952_b23-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/0006-291X(92)91234-H","article-title":"Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatant of cytokine activated cultured endothelial cells","volume":"187","author":"Pigott","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"key20180107225952_b24-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/MOH.0b013e3283523e1c","article-title":"Vascular endothelial-cadherin and vascular stability","volume":"19","author":"Dejana","year":"2012","journal-title":"Curr Opin Hematol"},{"key":"key20180107225952_b25-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/978-1-61779-191-8_18","article-title":"Role of endothelial cell-cell junctions in endothelial permeability","volume":"763","author":"Le Guelte","year":"2011","journal-title":"Methods Mol Biol"},{"key":"key20180107225952_b26-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1172\/JCI0214268","article-title":"Inhibition of endothelial cell survival and angiogenesis by protein kinase A","volume":"110","author":"Kim","year":"2002","journal-title":"J Clin Invest"},{"key":"key20180107225952_b27-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.18388\/abp.2000_3957","article-title":"The DFF40\/CAD endonuclease and its role in apoptosis","volume":"47","author":"Widlak","year":"2000","journal-title":"Acta Biochim Pol"},{"key":"key20180107225952_b28-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1038\/sj.onc.1202574","article-title":"MyD genes in negative growth control","volume":"17","author":"Liebermann","year":"1998","journal-title":"Oncogene"},{"key":"key20180107225952_b29-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1089\/ars.2005.7.482","article-title":"Redox regulation of apoptosis by members of the TNF superfamily","volume":"7","author":"Shakibaei","year":"2005","journal-title":"Antioxid Redox Signal"},{"key":"key20180107225952_b30-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1182\/blood-2010-07-295261","article-title":"NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis","volume":"117","author":"Kohler","year":"2011","journal-title":"Blood"},{"key":"key20180107225952_b31-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1038\/ng2112","article-title":"Modulation of morphogenesis by noncanonical Wnt signaling requires ATF\/CREB family-mediated transcriptional activation of TGF\u03b22","volume":"39","author":"Zhou","year":"2007","journal-title":"Nat Genet"},{"key":"key20180107225952_b32-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.cellbi.2005.11.003","article-title":"Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its beta-catenin-binding region","volume":"30","author":"Nakajima","year":"2006","journal-title":"Cell Biol Int"},{"key":"key20180107225952_b33-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1083\/jcb.129.4.895","article-title":"Endothelial receptor tyrosine kinases involved in angiogenesis","volume":"129","author":"Mustonen","year":"1995","journal-title":"J Cell Biol"},{"key":"key20180107225952_b34-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/10739680600930289","article-title":"T-type calcium channels in pulmonary vascular endothelium","volume":"13","author":"Zhou","year":"2006","journal-title":"Microcirculation"},{"key":"key20180107225952_b35-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1357-2725(98)00134-4","article-title":"The role of the 5 untranslated region of an mRNA in translation regulation during development","volume":"31","author":"van der Velden","year":"1999","journal-title":"Int J Biochem Cell Biol"},{"key":"key20180107225952_b36-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1040-8428(88)80016-7","article-title":"The production of myeloid blood cells and their regulation during health and disease","volume":"8","author":"Broxmeyer","year":"1988","journal-title":"Crit Rev Oncol Hematol"},{"key":"key20180107225952_b37-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1080\/10428190290011958","article-title":"The insulin-like growth factor system in hematopoietic cells","volume":"43","author":"Zumkeller","year":"2002","journal-title":"Leuk Lymphoma"},{"key":"key20180107225952_b38-ijmm-32-05-1204","first-page":"33","article-title":"Prevention of CCl4-induced liver cirrhosis by ribbon antisense to transforming growth factor-\u03b21","volume":"21","author":"Doh","year":"2008","journal-title":"Int J Mol Med"},{"key":"key20180107225952_b39-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1089\/10799900050023924","article-title":"Tumor necrosis factor-alpha and TNF-beta inhibit clonogenicity of mobilized human hematopoietic progenitors","volume":"20","author":"Skobin","year":"2000","journal-title":"J Interferon Cytokine Res"},{"key":"key20180107225952_b40-ijmm-32-05-1204","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s002770050192","article-title":"Macrophage-stimulating protein, a ligand for the RON receptor protein tyrosine kinase, suppresses myeloid progenitor cell proliferation and synergizes with vascular endothelial cell growth factor and members of the chemokine family","volume":"73","author":"Broxmeyer","year":"1996","journal-title":"Ann Hematol"},{"key":"key20180107225952_b41-ijmm-32-05-1204","first-page":"485","article-title":"Hematopoietic inhibitors elaborated by bone marrow endothelial cells","volume":"10","author":"Cheng","year":"2002","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ijmm.2013.1495\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T00:30:14Z","timestamp":1596501014000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2013.1495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,13]]},"references-count":41,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,9,13]]},"published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.3892\/ijmm.2013.1495"],"URL":"https:\/\/doi.org\/10.3892\/ijmm.2013.1495","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,13]]}}}