{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T02:41:47Z","timestamp":1775011307418,"version":"3.50.1"},"reference-count":67,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.3892\/ijmm.2015.2206","type":"journal-article","created":{"date-parts":[[2015,5,11]],"date-time":"2015-05-11T06:30:35Z","timestamp":1431325835000},"page":"282-288","source":"Crossref","is-referenced-by-count":33,"title":["A novel TBX5 loss-of-function mutation associated with sporadic dilated cardiomyopathy"],"prefix":"10.3892","volume":"36","author":[{"given":"WEI","family":"ZHOU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LAN","family":"ZHAO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JIN-QI","family":"JIANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WEI-FENG","family":"JIANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YI-QING","family":"YANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XING-BIAO","family":"QIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,5,11]]},"reference":[{"key":"key20180107233034_b1-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1172\/JCI62862","article-title":"Genetic mutations and mechanisms in dilated cardiomyopathy","volume":"123","author":"McNally","year":"2013","journal-title":"J Clin Invest"},{"key":"key20180107233034_b2-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nrcardio.2013.105","article-title":"Dilated cardiomyopathy: the complexity of a diverse genetic architecture","volume":"10","author":"Hershberger","year":"2013","journal-title":"Nat Rev Cardiol"},{"key":"key20180107233034_b3-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2217\/bmm.13.77","article-title":"Genetics in dilated cardiomyopathy","volume":"7","author":"Garcia-Pavia","year":"2013","journal-title":"Biomarkers Med"},{"key":"key20180107233034_b4-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ijcard.2012.07.014","article-title":"Sudden cardiac death in non-ischemic dilated cardiomyopathy: a critical appraisal of existing and potential risk stratification tools","volume":"167","author":"Koutalas","year":"2013","journal-title":"Int J Cardiol"},{"key":"key20180107233034_b5-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1253\/circj.CJ-11-0373","article-title":"Contribution of acquired factors to the pathogenesis of dilated cardiomyopathy. -The cause of dilated cardiomyopathy: genetic or acquired? (acquired-side)-","volume":"75","author":"Yoshikawa","year":"2011","journal-title":"Circ J"},{"key":"key20180107233034_b6-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1056\/NEJM200012073432304","article-title":"Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy","volume":"343","author":"Kamisago","year":"2000","journal-title":"N Engl J Med"},{"key":"key20180107233034_b7-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ajhg.2013.05.015","article-title":"Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy","volume":"93","author":"Arndt","year":"2013","journal-title":"Am J Hum Genet"},{"key":"key20180107233034_b8-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.gene.2013.09.022","article-title":"German Competence Network of Heart Failure: The HLA class II allele DQB1 0309 is associated with dilated cardiomyopathy","volume":"531","author":"Pankuweit","year":"2013","journal-title":"Gene"},{"key":"key20180107233034_b9-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ijcard.2012.09.070","article-title":"Dilated cardiomyopathy in patients with mutations in anoctamin 5","volume":"168","author":"Wahbi","year":"2013","journal-title":"Int J Cardiol"},{"key":"key20180107233034_b10-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.gene.2012.10.055","article-title":"German Competence Network of Heart Failure: Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy","volume":"512","author":"Ruppert","year":"2013","journal-title":"Gene"},{"key":"key20180107233034_b11-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ajhg.2014.07.004","article-title":"SPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy","volume":"95","author":"Agrawal","year":"2014","journal-title":"Am J Hum Genet"},{"key":"key20180107233034_b12-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.gene.2014.07.043","article-title":"Endothelin 1 gene as a modifier in dilated cardiomyopathy","volume":"548","author":"Matsa","year":"2014","journal-title":"Gene"},{"key":"key20180107233034_b13-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.cardiores.2004.03.025","article-title":"GATA transcription factors in the developing and adult heart","volume":"63","author":"Pikkarainen","year":"2004","journal-title":"Cardiovasc Res"},{"key":"key20180107233034_b14-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1249531","DOI":"10.1126\/science.1249531","article-title":"Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer","volume":"343","author":"Cai","year":"2014","journal-title":"Science"},{"key":"key20180107233034_b15-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.pharmthera.2005.03.005","article-title":"Cardiac transcription factor Csx\/Nkx2-5: Its role in cardiac development and diseases","volume":"107","author":"Akazawa","year":"2005","journal-title":"Pharmacol Ther"},{"key":"key20180107233034_b16-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/cvr\/cvr112","article-title":"Mechanisms of T-box gene function in the developing heart","volume":"91","author":"Greulich","year":"2011","journal-title":"Cardiovasc Res"},{"key":"key20180107233034_b17-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.semcdb.2006.11.012","article-title":"Re-employment of developmental transcription factors in adult heart disease","volume":"18","author":"Oka","year":"2007","journal-title":"Semin Cell Dev Biol"},{"key":"key20180107233034_b18-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/nature01827","article-title":"GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5","volume":"424","author":"Garg","year":"2003","journal-title":"Nature"},{"key":"key20180107233034_b19-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.yjmcc.2007.06.004","article-title":"Spectrum of heart disease associated with murine and human GATA4 mutation","volume":"43","author":"Rajagopal","year":"2007","journal-title":"J Mol Cell Cardiol"},{"key":"key20180107233034_b20-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"976","DOI":"10.5114\/aoms.2013.39788","article-title":"Mutation spectrum of GATA4 associated with congenital atrial septal defects","volume":"9","author":"Yang","year":"2013","journal-title":"Arch Med Sci"},{"key":"key20180107233034_b21-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1002\/humu.22434","article-title":"GATA4 loss-of-function mutations underlie familial tetralogy of Fallot","volume":"34","author":"Yang","year":"2013","journal-title":"Hum Mutat"},{"key":"key20180107233034_b22-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.gene.2013.10.028","article-title":"A novel mutation of GATA4 (K319E) is responsible for familial atrial septal defect and pulmonary valve stenosis","volume":"534","author":"Xiang","year":"2014","journal-title":"Gene"},{"key":"key20180107233034_b23-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.ijcard.2012.09.039","article-title":"Prevalence and spectrum of GATA5 mutations associated with congenital heart disease","volume":"165","author":"Jiang","year":"2013","journal-title":"Int J Cardiol"},{"key":"key20180107233034_b24-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/s00246-012-0482-6","article-title":"GATA5 loss-of-function mutation responsible for the congenital ventriculoseptal defect","volume":"34","author":"Wei","year":"2013","journal-title":"Pediatr Cardiol"},{"key":"key20180107233034_b25-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"34","DOI":"10.7150\/ijms.5270","article-title":"GATA5 loss-of-function mutations underlie tetralogy of fallot","volume":"10","author":"Wei","year":"2013","journal-title":"Int J Med Sci"},{"key":"key20180107233034_b26-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.3892\/ijmm.2014.1700","article-title":"GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve","volume":"33","author":"Shi","year":"2014","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b27-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.3892\/ijmm.2014.1674","article-title":"Somatic GATA5 mutations in sporadic tetralogy of Fallot","volume":"33","author":"Huang","year":"2014","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b28-ijmm-36-01-0282","first-page":"1065","article-title":"A novel GATA6 mutation associated with congenital ventricular septal defect","volume":"29","author":"Zheng","year":"2012","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b29-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3892\/ijmm.2012.1188","article-title":"Somatic mutations in the GATA6 gene underlie sporadic tetralogy of Fallot","volume":"31","author":"Huang","year":"2013","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b30-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1126\/science.281.5373.108","article-title":"Congenital heart disease caused by mutations in the transcription factor NKX2-5","volume":"281","author":"Schott","year":"1998","journal-title":"Science"},{"key":"key20180107233034_b31-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.gene.2013.04.043","article-title":"Two novel and functional DNA sequence variants within an upstream enhancer of the human NKX2-5 gene in ventricular septal defects","volume":"524","author":"Huang","year":"2013","journal-title":"Gene"},{"key":"key20180107233034_b32-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1016\/j.amjcard.2014.09.028","article-title":"A novel NKX2.5 loss-of-function mutation associated with congenital bicuspid aortic valve","volume":"114","author":"Qu","year":"2014","journal-title":"Am J Cardiol"},{"key":"key20180107233034_b33-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/hmg\/ddi055","article-title":"Common arterial trunk associated with a homeodomain mutation of NKX2.6","volume":"14","author":"Heathcote","year":"2005","journal-title":"Hum Mol Genet"},{"key":"key20180107233034_b34-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1136\/jmedgenet-2013-102100","article-title":"Conotruncal malformations and absent thymus due to a deleterious NKX2-6 mutation","volume":"51","author":"Ta-Shma","year":"2014","journal-title":"J Med Genet"},{"key":"key20180107233034_b35-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.ejmg.2014.08.005","article-title":"Prevalence and spectrum of Nkx2.6 mutations in patients with congenital heart disease","volume":"57","author":"Zhao","year":"2014","journal-title":"Eur J Med Genet"},{"key":"key20180107233034_b36-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1007\/s00246-014-1060-x","article-title":"A novel NKX2.6 mutation associated with congenital ventricular septal defect","volume":"36","author":"Wang","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"key20180107233034_b37-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1002\/ajmg.a.36783","article-title":"Identification of TBX5 mutations in a series of 94 patients with Tetralogy of Fallot","volume":"164A","author":"Baban","year":"2014","journal-title":"Am J Med Genet A"},{"key":"key20180107233034_b38-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/B978-0-12-387786-4.00008-7","article-title":"Transcription factor pathways and congenital heart disease","volume":"100","author":"McCulley","year":"2012","journal-title":"Curr Top Dev Biol"},{"key":"key20180107233034_b39-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00018-013-1430-1","article-title":"Of mice and men: molecular genetics of congenital heart disease","volume":"71","author":"Andersen","year":"2014","journal-title":"Cell Mol Life Sci"},{"key":"key20180107233034_b40-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"8127","DOI":"10.1007\/s11033-012-1660-6","article-title":"Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation","volume":"39","author":"Wang","year":"2012","journal-title":"Mol Biol Rep"},{"key":"key20180107233034_b41-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3892\/ijmm.2012.1189","article-title":"A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation","volume":"31","author":"Wang","year":"2013","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b42-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"783","DOI":"10.3892\/ijmm.2012.1068","article-title":"Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation","volume":"30","author":"Li","year":"2012","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b43-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"777","DOI":"10.6061\/clinics\/2013(06)09","article-title":"Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation","volume":"68","author":"Xie","year":"2013","journal-title":"Clinics (Sao Paulo)"},{"key":"key20180107233034_b44-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.3892\/ijmm.2013.1316","article-title":"A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation","volume":"31","author":"Huang","year":"2013","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b45-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1007\/s00246-014-0917-3","article-title":"Novel and highly lethal NKX2.5 missense mutation in a family with sudden death and ventricular arrhythmia","volume":"35","author":"Perera","year":"2014","journal-title":"Pediatr Cardiol"},{"key":"key20180107233034_b46-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"554","DOI":"10.7150\/ijms.8407","article-title":"Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation","volume":"11","author":"Yu","year":"2014","journal-title":"Int J Med Sci"},{"key":"key20180107233034_b47-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.3892\/ijmm.2014.1971","article-title":"NKX2-6 mutation predisposes to familial atrial fibrillation","volume":"34","author":"Wang","year":"2014","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b48-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1161\/CIRCRESAHA.107.168294","article-title":"A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation","volume":"102","author":"Postma","year":"2008","journal-title":"Circ Res"},{"key":"key20180107233034_b49-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/HCO.0000000000000051","article-title":"Genetic basis of atrial fibrillation","volume":"29","author":"Hong","year":"2014","journal-title":"Curr Opin Cardiol"},{"key":"key20180107233034_b50-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.bbrc.2013.09.023","article-title":"GATA4 loss-of-function mutation underlies familial dilated cardiomyopathy","volume":"439","author":"Li","year":"2013","journal-title":"Biochem Biophys Res Commun"},{"key":"key20180107233034_b51-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3892\/ijmm.2013.1600","article-title":"A novel GATA4 loss-of-function mutation responsible for familial dilated cardiomyopathy","volume":"33","author":"Zhao","year":"2014","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b52-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3892\/ijmm.2014.2050","article-title":"GATA5 loss-of-function mutation in familial dilated cardiomyopathy","volume":"35","author":"Zhang","year":"2015","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b53-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.3892\/ijmm.2014.1896","article-title":"GATA6 loss-of-function mutations contribute to familial dilated cardiomyopathy","volume":"34","author":"Xu","year":"2014","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b54-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1161\/CIRCGENETICS.113.000057","article-title":"Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy","volume":"6","author":"Costa","year":"2013","journal-title":"Circ Cardiovasc Genet"},{"key":"key20180107233034_b55-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"478","DOI":"10.3892\/ijmm.2014.2029","article-title":"A novel NKX2-5 loss-of-function mutation predisposes to familial dilated cardiomyopathy and arrhythmias","volume":"35","author":"Yuan","year":"2015","journal-title":"Int J Mol Med"},{"key":"key20180107233034_b56-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.bbrc.2015.02.094","article-title":"TBX5 loss-of-function mutation contributes to familial dilated cardiomyopathy","volume":"459","author":"Zhang","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"key20180107233034_b57-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.gene.2014.07.022","article-title":"Prevalence and spectrum of GATA4 mutations associated with sporadic dilated cardiomyopathy","volume":"548","author":"Li","year":"2014","journal-title":"Gene"},{"key":"key20180107233034_b58-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1161\/CIRCGENETICS.110.937805","article-title":"Prevalence of desmosomal protein gene mutations in patients with dilated cardiomyopathy","volume":"3","author":"Elliott","year":"2010","journal-title":"Circ Cardiovasc Genet"},{"key":"key20180107233034_b59-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/01.CIR.93.5.841","article-title":"Report of the 1995 World Health Organization\/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies","volume":"93","author":"Richardson","year":"1996","journal-title":"Circulation"},{"key":"key20180107233034_b60-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/90123","article-title":"Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation","volume":"28","author":"Hiroi","year":"2001","journal-title":"Nat Genet"},{"key":"key20180107233034_b61-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0012-1606(03)00385-3","article-title":"Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart","volume":"262","author":"Stennard","year":"2003","journal-title":"Dev Biol"},{"key":"key20180107233034_b62-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/dvdy.20201","article-title":"T-box genes and heart development: putting the \u2018T\u2019 in heart","volume":"232","author":"Plageman","year":"2005","journal-title":"Dev Dyn"},{"key":"key20180107233034_b63-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/dbio.1999.9298","article-title":"Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome","volume":"211","author":"Bruneau","year":"1999","journal-title":"Dev Biol"},{"key":"key20180107233034_b64-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0092-8674(01)00493-7","article-title":"A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease","volume":"106","author":"Bruneau","year":"2001","journal-title":"Cell"},{"key":"key20180107233034_b65-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"5025","DOI":"10.1093\/hmg\/ddu215","article-title":"Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation","volume":"23","author":"Misra","year":"2014","journal-title":"Hum Mol Genet"},{"key":"key20180107233034_b66-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1086\/519530","article-title":"Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy","volume":"81","author":"Kirk","year":"2007","journal-title":"Am J Hum Genet"},{"key":"key20180107233034_b67-ijmm-36-01-0282","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/1471-2350-9-88","article-title":"Functional analysis of the novel TBX5 c.1333delC mutation resulting in an extended TBX5 protein","volume":"9","author":"B\u00f6hm","year":"2008","journal-title":"BMC Med Genet"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ijmm.2015.2206\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,24]],"date-time":"2019-08-24T18:23:28Z","timestamp":1566671008000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2015.2206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,11]]},"references-count":67,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,5,11]]},"published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.3892\/ijmm.2015.2206"],"URL":"https:\/\/doi.org\/10.3892\/ijmm.2015.2206","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,11]]}}}