{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:08:54Z","timestamp":1785859734398,"version":"3.56.0"},"reference-count":27,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.3892\/ijmm.2015.2334","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T03:43:23Z","timestamp":1441165403000},"page":"1215-1222","source":"Crossref","is-referenced-by-count":49,"title":["Electro-acupuncture exerts beneficial effects against cerebral ischemia and promotes the proliferation of neural progenitor cells in the cortical peri-infarct area through the Wnt\/\u03b2-catenin signaling pathway"],"prefix":"10.3892","volume":"36","author":[{"given":"BIN","family":"CHEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JING","family":"TAO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YUKUN","family":"LIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RUHUI","family":"LIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WEILIN","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LIDIAN","family":"CHEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2015,9,2]]},"reference":[{"key":"key20180107232813_b1-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0140-6736(08)60694-7","article-title":"Stroke","volume":"371","author":"Donnan","year":"2008","journal-title":"Lancet"},{"key":"key20180107232813_b2-ijmm-36-05-1215","first-page":"e2","article-title":"Statistics Committee and Stroke Statistics Subcommittee: Heart disease and stroke statistics - 2012 update: a report from the American Heart Association","volume-title":"Circulation","author":"Roger","year":"2012"},{"key":"key20180107232813_b3-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.1242\/dev.01165","article-title":"The Wnt\/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells","volume":"131","author":"Hirabayashi","year":"2004","journal-title":"Development"},{"key":"key20180107232813_b4-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.brainres.2008.01.007","article-title":"Hypothermia blocks beta-catenin degradation after focal ischemia in rats","volume":"1198","author":"Zhang","year":"2008","journal-title":"Brain Res"},{"key":"key20180107232813_b5-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/jcbfm.2008.111","article-title":"Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia","volume":"29","author":"Mastroiacovo","year":"2009","journal-title":"J Cereb Blood Flow Metab"},{"key":"key20180107232813_b6-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.brainres.2012.12.015","article-title":"Estrogen regulation of Dkk1 and Wnt\/\u03b2-Catenin signaling in neurodegenerative disease","volume":"1514","author":"Scott","year":"2013","journal-title":"Brain Res"},{"key":"key20180107232813_b7-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ejphar.2014.05.019","article-title":"Promoting neurogenesis via Wnt\/\u03b2-catenin signaling pathway accounts for the neurorestorative effects of morroniside against cerebral ischemia injury","volume":"738","author":"Sun","year":"2014","journal-title":"Eur J Pharmacol"},{"key":"key20180107232813_b8-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.ydbio.2012.12.001","article-title":"Constitutive activation of \u03b2-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system","volume":"374","author":"P\u00f6schl","year":"2013","journal-title":"Dev Biol"},{"key":"key20180107232813_b9-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/nature04108","article-title":"Wnt signalling regulates adult hippocampal neurogenesis","volume":"437","author":"Lie","year":"2005","journal-title":"Nature"},{"key":"key20180107232813_b10-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3736\/jintegrmed2013021","article-title":"Traditional herbal medicine in preventing recurrence after resection of small hepatocellular carcinoma: a multicenter randomized controlled trial","volume":"11","author":"Zhai","year":"2013","journal-title":"J Integr Med"},{"key":"key20180107232813_b11-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.06.005","article-title":"Rationale and design of a multicenter, phase 2 clinical trial to investigate the efficacy of traditional Chinese medicine SaiLuoTong in vascular dementia","volume":"23","author":"Liang","year":"2014","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"key20180107232813_b12-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S2095-4964(14)60003-0","article-title":"Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo","volume":"12","author":"Wang","year":"2014","journal-title":"J Integr Med"},{"key":"key20180107232813_b13-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S2095-4964(14)60019-4","article-title":"The roles of traditional Chinese medicine in gene therapy","volume":"12","author":"Ling","year":"2014","journal-title":"J Integr Med"},{"key":"key20180107232813_b14-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1038\/srep01070","article-title":"Using microPET imaging in quantitative verification of the acupuncture effect in ischemia stroke treatment","volume":"3","author":"Liu","year":"2013","journal-title":"Sci Rep"},{"key":"key20180107232813_b15-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"e56736","DOI":"10.1371\/journal.pone.0056736","article-title":"Electroacupuncture acutely improves cerebral blood flow and attenuates moderate ischemic injury via an endothelial mechanism in mice","volume":"8","author":"Kim","year":"2013","journal-title":"PLoS One"},{"key":"key20180107232813_b16-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1742-2094-10-63","article-title":"Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1","volume":"10","author":"Jin","year":"2013","journal-title":"J Neuroinflammation"},{"key":"key20180107232813_b17-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1179\/174313209X414506","article-title":"Electroacupuncture improves neurological deficits and enhances proliferation and differentiation of endogenous nerve stem cells in rats with focal cerebral ischemia","volume":"32","author":"Tao","year":"2010","journal-title":"Neurol Res"},{"key":"key20180107232813_b18-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1161\/STROKEAHA.111.635029","article-title":"Bridging therapy in acute ischemic stroke: a systematic review and meta-analysis","volume":"43","author":"Mazighi","year":"2012","journal-title":"Stroke"},{"key":"key20180107232813_b19-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.1161\/STROKEAHA.109.573576","article-title":"Acupuncture in post-stroke rehabilitation: a systematic review and meta-analysis of randomized trials","volume":"41","author":"Wu","year":"2010","journal-title":"Stroke"},{"key":"key20180107232813_b20-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3109\/00207454.2013.840781","article-title":"Electroacupuncture enhances hippocampal NSCs proliferation in cerebral ischemia-reperfusion injured rats via activation of notch signaling pathway","volume":"124","author":"Tao","year":"2014","journal-title":"Int J Neurosci"},{"key":"key20180107232813_b21-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"7926","DOI":"10.1523\/JNEUROSCI.4303-11.2012","article-title":"Self-renewal and differentiation of reactive astrocyte-derived neural stem\/progenitor cells isolated from the cortical peri-infarct area after stroke","volume":"32","author":"Shimada","year":"2012","journal-title":"J Neurosci"},{"key":"key20180107232813_b22-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1111\/j.1460-9568.2009.06732.x","article-title":"Isolation and characterization of neural stem\/progenitor cells from post-stroke cerebral cortex in mice","volume":"29","author":"Nakagomi","year":"2009","journal-title":"Eur J Neurosci"},{"key":"key20180107232813_b23-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1089\/scd.2011.0279","article-title":"Ischemia-induced neural stem\/progenitor cells in the pia mater following cortical infarction","volume":"20","author":"Nakagomi","year":"2011","journal-title":"Stem Cells Dev"},{"key":"key20180107232813_b24-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","article-title":"Reversible middle cerebral artery occlusion without craniectomy in rats","volume":"20","author":"Longa","year":"1989","journal-title":"Stroke"},{"key":"key20180107232813_b25-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/jcbfm.1990.47","article-title":"A semiautomated method for measuring brain infarct volume","volume":"10","author":"Swanson","year":"1990","journal-title":"J Cereb Blood Flow Metab"},{"key":"key20180107232813_b26-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1126\/science.281.5382.1509","article-title":"Identification of c-MYC as a target of the APC pathway","volume":"281","author":"He","year":"1998","journal-title":"Science"},{"key":"key20180107232813_b27-ijmm-36-05-1215","doi-asserted-by":"crossref","first-page":"5522","DOI":"10.1073\/pnas.96.10.5522","article-title":"The cyclin D1 gene is a target of the beta-catenin\/LEF-1 pathway","volume":"96","author":"Shtutman","year":"1999","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ijmm.2015.2334\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T18:57:27Z","timestamp":1515351447000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2015.2334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,2]]},"references-count":27,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2015,9,2]]},"published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.3892\/ijmm.2015.2334"],"URL":"https:\/\/doi.org\/10.3892\/ijmm.2015.2334","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,2]]}}}