{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:24:46Z","timestamp":1775150686605,"version":"3.50.1"},"reference-count":39,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Mol Med"],"DOI":"10.3892\/ijmm.2018.3768","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T10:56:17Z","timestamp":1531392977000},"source":"Crossref","is-referenced-by-count":2,"title":["Identification of genes and signaling pathways associated with arthrogryposis\u2011renal dysfunction\u2011cholestasis syndrome using weighted correlation network analysis"],"prefix":"10.3892","author":[{"given":"Miao","family":"Chai","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liju","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolei","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihui","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiabing","family":"Bi","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bohai","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The First Hospital of Harbin, Harbin, Heilongjiang 150010, P.R.\ufffdChina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,7,12]]},"reference":[{"key":"key20200713175732_b1-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1038\/ng.538","article-title":"Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization","volume":"42","author":"Cullinane","year":"2010","journal-title":"Nat Genet"},{"key":"key20200713175732_b2-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s13052-014-0077-3","article-title":"Arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome: From molecular genetics to clinical features","volume":"40","author":"Zhou","year":"2014","journal-title":"Ital J Pediatr"},{"key":"key20200713175732_b3-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1007\/s00439-006-0232-z","article-title":"Clinical and molecular genetic features of ARC syndrome","volume":"120","author":"Gissen","year":"2006","journal-title":"Hum Genet"},{"key":"key20200713175732_b4-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1038\/jp.2013.62","article-title":"ARC syndrome in preterm baby","volume":"33","author":"Elmeery","year":"2013","journal-title":"J Perinatol"},{"key":"key20200713175732_b5-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1136\/adc.85.5.415","article-title":"ARC syndrome: An expanding range of phenotypes","volume":"85","author":"Eastham","year":"2001","journal-title":"Arch Dis Child"},{"key":"key20200713175732_b6-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"E330","DOI":"10.1002\/humu.20900","article-title":"Molecular investigations to improve diagnostic accuracy in patients with ARC syndrome","volume":"30","author":"Cullinane","year":"2009","journal-title":"Hum Mutat"},{"key":"key20200713175732_b7-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1159\/000015571","article-title":"Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vps33b","volume":"89","author":"Carim","year":"2000","journal-title":"Cytogenet Cell Genet"},{"key":"key20200713175732_b8-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"5295","DOI":"10.1242\/dev.02140","article-title":"Zebrafish vps33b, an ortholog of the gene responsible for human arthrogryposis-renal dysfunction-cholestasis syndrome, regulates biliary development downstream of the onecut transcription factor hnf6","volume":"132","author":"Matthews","year":"2005","journal-title":"Development"},{"key":"key20200713175732_b9-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1034\/j.1600-0854.2001.20705.x","article-title":"The class C Vps complex functions at multiple stages of the vacuolar transport pathway","volume":"2","author":"Peterson","year":"2001","journal-title":"Traffic"},{"key":"key20200713175732_b10-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1001\/archderm.144.3.334","article-title":"Defective lamellar granule secretion in arthrogryposis, renal dysfunction, and cholestasis syndrome caused by a mutation in VPS33B","volume":"144","author":"Hershkovitz","year":"2008","journal-title":"Arch Dermatol"},{"key":"key20200713175732_b11-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1182\/blood-2014-12-614677","article-title":"VPS33B regulates protein sorting into and maturation of \u03b1-granule progenitor organelles in mouse megakaryocytes","volume":"126","author":"Bem","year":"2015","journal-title":"Blood"},{"key":"key20200713175732_b12-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"12111","DOI":"10.1038\/ncomms12111","article-title":"Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis","volume":"7","author":"Banushi","year":"2016","journal-title":"Nature Communications"},{"key":"key20200713175732_b13-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/j.jhep.2017.01.001","article-title":"Vps33b is crucial for structural and functional hepatocyte polarity","volume":"66","author":"Hanley","year":"2017","journal-title":"J Hepatol"},{"key":"key20200713175732_b14-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1093\/bioinformatics\/17.6.520","article-title":"Missing value estimation methods for DNA microarrays","volume":"17","author":"Troyanskaya","year":"2001","journal-title":"Bioinformatics"},{"key":"key20200713175732_b15-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1093\/bioinformatics\/18.12.1585","article-title":"Robust estimators for expression analysis","volume":"18","author":"Hubbell","year":"2002","journal-title":"Bioinformatics"},{"key":"key20200713175732_b16-ijmm-42-04-2238","doi-asserted-by":"publisher","DOI":"10.2202\/1544-6115.1287","article-title":"A comparison of normalization techniques for microRNA microarray data","volume":"7","author":"Rao","year":"2008","journal-title":"Stat Appl Genet Mol Biol"},{"key":"key20200713175732_b17-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/0-387-29362-0_23","article-title":"Limma: Linear models for microarray data","author":"Smyth","year":"2005","journal-title":"Bioinformatics and computational biology solutions using R and Bioconductor Springer"},{"key":"key20200713175732_b18-ijmm-42-04-2238","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: A practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Statist Soc B"},{"key":"key20200713175732_b19-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/1471-2229-14-169","article-title":"RNA-seq analyses of multiple meristems of soybean: Novel and alternative transcripts, evolutionary and functional implications","volume":"14","author":"Wang","year":"2014","journal-title":"BMC Plant Biol"},{"key":"key20200713175732_b20-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: An R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"key20200713175732_b21-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1126\/science.1073374","article-title":"Hierarchical organization of modularity in metabolic networks","volume":"297","author":"Ravasz","year":"2002","journal-title":"Science"},{"issue":"Database Issue","key":"key20200713175732_b22-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"D808","DOI":"10.1093\/nar\/gks1094","article-title":"STRING v9.1: Protein-protein interaction networks, with increased coverage and integration","volume":"41","author":"Franceschini","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"key20200713175732_b23-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: A software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"key20200713175732_b24-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2105-4-2","article-title":"An automated method for finding molecular complexes in large protein interaction networks","volume":"4","author":"Bader","year":"2003","journal-title":"BMC Bioinformatics"},{"key":"key20200713175732_b25-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"3448","DOI":"10.1093\/bioinformatics\/bti551","article-title":"BiNGO: A Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks","volume":"21","author":"Maere","year":"2005","journal-title":"Bioinformatics"},{"key":"key20200713175732_b26-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1093\/bioinformatics\/bth088","article-title":"GOstat: Find statistically over-represented Gene Ontologies within a group of genes","volume":"20","author":"Beissbarth","year":"2004","journal-title":"Bioinformatics"},{"issue":"Web Server Issue","key":"key20200713175732_b27-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"W720","DOI":"10.1093\/nar\/gkl167","article-title":"KOBAS server: A web-based platform for automated annotation and pathway identification","volume":"34","author":"Wu","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"key20200713175732_b28-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1186\/s13073-014-0095-1","article-title":"Systematic evaluation of connectivity map for disease indications","volume":"6","author":"Cheng","year":"2014","journal-title":"Genome Med"},{"key":"key20200713175732_b29-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/nature02761","article-title":"Inferences, questions and possibilities in Toll-like receptor signalling","volume":"430","author":"Beutler","year":"2004","journal-title":"Nature"},{"key":"key20200713175732_b30-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.immuni.2010.09.010","article-title":"The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes","volume":"33","author":"Husebye","year":"2010","journal-title":"Immunity"},{"key":"key20200713175732_b31-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.1021\/pr5002466","article-title":"Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics","volume":"13","author":"Sjoelund","year":"2014","journal-title":"J Proteome Res"},{"key":"key20200713175732_b32-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.15252\/embj.201487888","article-title":"TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis","volume":"33","author":"Yu","year":"2014","journal-title":"EMBO J"},{"key":"key20200713175732_b33-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1038\/ng1325","article-title":"Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome","volume":"36","author":"Gissen","year":"2004","journal-title":"Nat Genet"},{"key":"key20200713175732_b34-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1016\/j.bbrc.2005.07.195","article-title":"SNARE-mediated trafficking of alpha5beta1 integrin is required for spreading in CHO cells","volume":"335","author":"Skalski","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"key20200713175732_b35-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.yexcr.2004.12.004","article-title":"Inhibition of SNARE-mediated membrane traffic impairs cell migration","volume":"305","author":"Tayeb","year":"2005","journal-title":"Exp Cell Res"},{"key":"key20200713175732_b36-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"e9759","DOI":"10.1371\/journal.pone.0009759","article-title":"Loss of SNAP29 impairs endocytic recycling and cell motility","volume":"5","author":"Rapaport","year":"2010","journal-title":"PLoS One"},{"key":"key20200713175732_b37-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"15087","DOI":"10.1073\/pnas.0503702102","article-title":"Rab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells","volume":"102","author":"Wakabayashi","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713175732_b38-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1126\/science.290.5497.1771","article-title":"Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters","volume":"290","author":"Berge","year":"2000","journal-title":"Science"},{"key":"key20200713175732_b39-ijmm-42-04-2238","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/3034","article-title":"A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis","volume":"20","author":"Strautnieks","year":"1998","journal-title":"Nature genetics"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"deposited":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T04:15:33Z","timestamp":1720412133000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2018.3768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,12]]},"references-count":39,"URL":"https:\/\/doi.org\/10.3892\/ijmm.2018.3768","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,12]]}}}