{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T19:18:54Z","timestamp":1648754334355},"reference-count":58,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Mol Med"],"DOI":"10.3892\/ijmm.2020.4472","type":"journal-article","created":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T09:15:58Z","timestamp":1579684558000},"source":"Crossref","is-referenced-by-count":1,"title":["iTRAQ\u2011based quantitative proteomics analysis of the potential application of secretoneurin gene therapy for cardiac hypertrophy induced by DL\u2011isoproterenol hydrochloride in mice"],"prefix":"10.3892","author":[{"given":"Huali","family":"Chen","sequence":"first","affiliation":[{"name":"College of Pharmacy, Chongqing Medical University, Chongqing 400016, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjun","family":"Wu","sequence":"additional","affiliation":[{"name":"Institute of Life Science, Chongqing Medical University, Chongqing 400016, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biotherapy, Molecular Medicine Research Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Life Science, Chongqing Medical University, Chongqing 400016, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Life Science, Chongqing Medical University, Chongqing 400016, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Chongqing Medical University, Chongqing 400016, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"key":"key20200713162422_b1-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1146\/annurev.physiol.65.092101.142243","article-title":"Cardiac hypertrophy: The good, the bad, and the ugly","volume":"65","author":"Frey","year":"2003","journal-title":"Annu Rev Physiol"},{"key":"key20200713162422_b2-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"57B","DOI":"10.1016\/S0735-1097(85)80528-3","article-title":"Pathogenesis of ventricular hypertrophy","volume":"5","author":"Oparil","year":"1985","journal-title":"J Am Coll Cardiol"},{"key":"key20200713162422_b3-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s00424-011-0930-9","article-title":"Role of auto-crine\/paracrine mechanisms in response to myocardial strain","volume":"462","author":"Cingolani","year":"2011","journal-title":"Pflugers Arch"},{"key":"key20200713162422_b4-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.molmed.2010.12.003","article-title":"The cardiokine story unfolds: Ischemic stress-induced protein secretion in the heart","volume":"17","author":"Doroudgar","year":"2011","journal-title":"Trends Mol Med"},{"issue":"Suppl","key":"key20200713162422_b5-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.1097\/01.hjh.0000388492.73954.0b","article-title":"The cardiokine story unfolds: Ischemic stress-induced protein secretion in the heart","volume":"28","author":"Finckenberg","year":"2010","journal-title":"J Hypertens"},{"key":"key20200713162422_b6-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2491","DOI":"10.1161\/CIRCULATIONAHA.111.076950","article-title":"The angiogenic factor secretoneurin induces coronary angiogenesis in a model of myocardial infarction by stimulation of vascular endothelial growth factor signaling in endothelial cells","volume":"126","author":"Albrecht-Schgoer","year":"2012","journal-title":"Circulation"},{"key":"key20200713162422_b7-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0003-9969(98)00016-8","article-title":"Secretoneurin, a novel neuropeptide, in the human dental pulp","volume":"43","author":"Pertl","year":"1998","journal-title":"Arch Oral Biol"},{"key":"key20200713162422_b8-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1053\/euhj.2001.2977","article-title":"Chromogranin A in heart failure; a novel neurohumoral factor and a predictor for mortality","volume":"23","author":"Ceconi","year":"2002","journal-title":"Eur Heart J"},{"key":"key20200713162422_b9-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1093\/eurjhf\/hfq055","article-title":"Prognostic value of chromogranin A in chronic heart failure: Data from the GISSI-Heart Failure trial","volume":"12","author":"Rosjo","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"key20200713162422_b10-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1161\/CIRCHEARTFAILURE.109.867747","article-title":"Chromogranin B in heart failure: A putative cardiac biomarker expressed in the failing myocardium","volume":"3","author":"Rosjo","year":"2010","journal-title":"Circ Heart Fail"},{"key":"key20200713162422_b11-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1093\/eurheartj\/ehn513","article-title":"Prognostic value of circulating chromogranin A levels in acute coronary syndromes","volume":"30","author":"Jansson","year":"2009","journal-title":"Eur Heart J"},{"key":"key20200713162422_b12-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.bios.2015.02.022","article-title":"Ultrasensitive electrochemical detection of secretoneurin based on Pb(2+)-decorated reduced graphene oxide-tetraethylene pentamine as a label","volume":"69","author":"Yuan","year":"2015","journal-title":"Biosens Bioelectron"},{"key":"key20200713162422_b13-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"e37401","DOI":"10.1371\/journal.pone.0037401","article-title":"Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties","volume":"7","author":"Rosjo","year":"2012","journal-title":"PLoS One"},{"key":"key20200713162422_b14-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ejphar.2018.01.008","article-title":"Secretoneurin suppresses cardiac hypertrophy through suppression of oxidant stress","volume":"822","author":"Chen","year":"2018","journal-title":"Eur J Pharmacol"},{"key":"key20200713162422_b15-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1093\/jxb\/erj168","article-title":"A perspective on the use of iTRAQ reagent technology for protein complex and profiling studies","volume":"57","author":"Zieske","year":"2006","journal-title":"J Exp Bot"},{"key":"key20200713162422_b16-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.neuroscience.2015.04.006","article-title":"iTRAQ-based quantitative analysis of hippocampal postsynaptic density-associated proteins in a rat chronic mild stress model of depression","volume":"298","author":"Han","year":"2015","journal-title":"Neuroscience"},{"key":"key20200713162422_b17-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2466","DOI":"10.1021\/pr501324n","article-title":"Proteomic signature of endothelial dysfunction identified in the serum of acute ischemic stroke patients by the itraq-based lc-MS approach","volume":"14","author":"Sharma","year":"2015","journal-title":"J Proteome Res"},{"key":"key20200713162422_b18-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.neuroscience.2016.05.055","article-title":"iTRAQ technology-based identification of human peripheral serum proteins associated with depression","volume":"330","author":"Wang","year":"2016","journal-title":"Neuroscience"},{"key":"key20200713162422_b19-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1002\/pmic.201300383","article-title":"Discovery and identification of serum potential biomarkers for pulmonary tuberculosis using iTRAQ-coupled two-dimensional LC-MS\/MS","volume":"14","author":"Xu","year":"2014","journal-title":"Proteomics"},{"key":"key20200713162422_b20-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/s12967-016-0898-5","article-title":"Proteomic analysis of short-term preload-induced eccentric cardiac hypertrophy","volume":"14","author":"Mohamed","year":"2016","journal-title":"J Transl Med"},{"key":"key20200713162422_b21-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1016\/j.jmb.2014.10.026","article-title":"Comparative proteome profiling during cardiac hypertrophy and myocardial infarction reveals altered glucose oxidation by differential activation of pyruvate dehydrogenase e1 component subunit \u03b2","volume":"427","author":"Mitra","year":"2015","journal-title":"J Mol Biol"},{"key":"key20200713162422_b22-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1186\/1479-5876-11-130","article-title":"A proteomic view of isoproterenol induced cardiac hypertrophy: Prohibitin identified as a potential biomarker in rats","volume":"11","author":"Chowdhury","year":"2013","journal-title":"J Transl Med"},{"key":"key20200713162422_b23-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1159\/000276567","article-title":"A proteomic approach to determine changes in proteins involved in the myocardial metabolism in left ventricles of spontaneously hypertensive rats","volume":"25","author":"Zamorano-Leon","year":"2010","journal-title":"Cell Physiol Biochem"},{"key":"key20200713162422_b24-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12014-016-9121-1","article-title":"Mass spectrometry-based approaches to targeted quantitative proteomics in cardiovascular disease","volume":"13","author":"Mesaros","year":"2016","journal-title":"Clin Proteomics"},{"key":"key20200713162422_b25-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1038\/nprot.2007.135","article-title":"A protocol for rapid generation of recombinant adenoviruses using the AdEasy system","volume":"2","author":"Luo","year":"2007","journal-title":"Nat Protoc"},{"key":"key20200713162422_b26-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/978-1-4939-9139-6_19","article-title":"AAV vectors for efficient gene delivery to rodent hearts","volume":"1950","author":"Lopez-Gordo","year":"2019","journal-title":"Methods Mol Biol"},{"key":"key20200713162422_b27-ijmm-45-03-0793","article-title":"Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors","author":"Garcia-Olloqui","year":"2019","journal-title":"J Tissue Eng Regen Med"},{"key":"key20200713162422_b28-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2673","DOI":"10.1172\/JCI27643.","article-title":"Transcription factor MITF regulates cardiac growth and hypertrophy","volume":"116","author":"Tshori","year":"2006","journal-title":"J Clin Invest"},{"key":"key20200713162422_b29-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"e64757","DOI":"10.1371\/journal.pone.0064757","article-title":"Intermedin suppresses pressure overload cardiac hypertrophy through activation of autophagy","volume":"8","author":"Chen","year":"2013","journal-title":"PLoS One"},{"key":"key20200713162422_b30-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00395-016-0531-z","article-title":"SIRT6 protects cardiomyocytes against ischemia\/reperfusion injury by augmenting FoxO3\u03b1-dependent antioxidant defense mechanisms","volume":"111","author":"Wang","year":"2016","journal-title":"Basic Res Cardiol"},{"key":"key20200713162422_b31-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2727","DOI":"10.1161\/CIRCULATIONAHA.110.942268","article-title":"Molecular pathways underlying cardiac remodeling during pathophysiological stimulation","volume":"122","author":"Kehat","year":"2010","journal-title":"Circulation"},{"key":"key20200713162422_b32-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1007\/s001090050176","article-title":"Catecholamine-induced cardiac hypertrophy: Significance of proto-oncogene expression","volume":"75","author":"Zimmer","year":"1997","journal-title":"J Mol Med (Berl)"},{"key":"key20200713162422_b33-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1097\/FJC.0b013e3181ed064f","article-title":"Congestive heart failure: Where homeostasis begets dyshomeostasis","volume":"56","author":"Kamalov","year":"2010","journal-title":"J Cardiovasc Pharmacol"},{"key":"key20200713162422_b34-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1182\/blood.V91.5.1527","article-title":"Secretoneurin, a novel neuropeptide, is a potent chemoattractant for human eosinophils","volume":"91","author":"Dunzendorfer","year":"1998","journal-title":"Blood"},{"key":"key20200713162422_b35-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1111\/j.1460-9568.1994.tb00996.x","article-title":"Human and rat primary C-fibre afferents store and release secre-toneurin, a novel neuropeptide","volume":"6","author":"Kirchmair","year":"1994","journal-title":"Eur J Neurosci"},{"key":"key20200713162422_b36-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"e74029","DOI":"10.1371\/journal.pone.0074029","article-title":"Secretoneurin gene therapy improves blood flow in an ischemia model in type 1 diabetic mice by enhancing therapeutic neovascularization","volume":"8","author":"Schgoer","year":"2013","journal-title":"PLoS One"},{"key":"key20200713162422_b37-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"H1159","DOI":"10.1152\/ajpheart.00519.2010","article-title":"Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries","volume":"300","author":"Chan","year":"2011","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key20200713162422_b38-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1161\/CIRCRESAHA.109.199513","article-title":"Gene therapy with the angiogenic cytokine secretoneurin induces therapeutic angiogenesis by a nitric oxide-dependent mechanism","volume":"105","author":"Schgoer","year":"2009","journal-title":"Circ Res"},{"key":"key20200713162422_b39-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1080\/15384047.2018.1472192","article-title":"iTRAQ-based quantitative proteomic analysis of differentially expressed proteins in chemoresistant nasopharyngeal carcinoma","volume":"19","author":"Wang","year":"2018","journal-title":"Cancer Biol Ther"},{"key":"key20200713162422_b40-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jprot.2018.12.027","article-title":"iTRAQ-based quantitative proteomics reveals insights into metabolic and molecular responses of glucose-grown cells of Rubrivivax benzoatilyticus JA2","volume":"194","author":"Gupta","year":"2019","journal-title":"J Proteomics"},{"key":"key20200713162422_b41-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.biopha.2017.04.127","article-title":"Liquid chromatography-mass spectrometry-based quantitative proteomics analysis reveals chondroprotective effects of astragaloside IV in interleukin-1\u03b2-induced SW1353 chondrocyte-like cells","volume":"91","author":"Luo","year":"2017","journal-title":"Biomed Pharmacother"},{"key":"key20200713162422_b42-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.psyneuen.2017.09.005","article-title":"Identification of plasma biomarkers for distinguishing bipolar depression from major depressive disorder by iTRAQ-coupled LC-MS\/MS and bioinformatics analysis","volume":"86","author":"Ren","year":"2017","journal-title":"Psychoneuroendocrinology"},{"key":"key20200713162422_b43-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.plaphy.2019.10.018","article-title":"iTRAQ-based proteomics reveals key role of gamma-amino-butyric acid (GABA) in regulating drought tolerance in perennial creeping bentgrass (Agrostis stolonifera)","volume":"145","author":"Li","year":"2019","journal-title":"Plant Physiol Biochem"},{"key":"key20200713162422_b44-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"103558","DOI":"10.1016\/j.jprot.2019.103558","article-title":"ITRAQ-based quantitative proteomic analysis of MG63 in response to HIF-1\u03b1 inducers","volume":"211","author":"Chen","year":"2019","journal-title":"J Proteomics"},{"key":"key20200713162422_b45-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s12014-019-9259-8","article-title":"iTRAQ-based quantitative proteomic analysis provides insight for molecular mechanism of neuroticism","volume":"16","author":"Tian","year":"2019","journal-title":"Clin Proteomics"},{"key":"key20200713162422_b46-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2256","DOI":"10.1161\/CIRCULATIONAHA.116.026099","article-title":"Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy","volume":"137","author":"Diguet","year":"2018","journal-title":"Circulation"},{"key":"key20200713162422_b47-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1002\/jcp.25945","article-title":"HSF1 phosphorylation by ERK\/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy","volume":"233","author":"Huang","year":"2018","journal-title":"J Cell Physiol"},{"key":"key20200713162422_b48-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"H1119","DOI":"10.1152\/ajpheart.00284.2017","article-title":"Temporal dynamics of cardiac hypertrophic growth in response to pressure overload","volume":"313","author":"Wang","year":"2017","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key20200713162422_b49-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1007\/s00421-008-0751-5","article-title":"Myosin heavy chain isoform distribution in single fibres of bodybuilders","volume":"103","author":"Kesidis","year":"2008","journal-title":"Eur J Appl Physiol"},{"key":"key20200713162422_b50-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.ejmg.2017.06.008","article-title":"Digenic inheritance of mutations in the cardiac troponin (TNNT2) and cardiac beta myosin heavy chain (MYH7) as the cause of severe dilated cardiomyopathy","volume":"60","author":"Petropoulou","year":"2017","journal-title":"Eur J Med Genet"},{"key":"key20200713162422_b51-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1093\/europace\/euv043","article-title":"Dual LQT1 and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1, MYH7, MYLK2, and TMEM70 genes in a three-generation Chinese family","volume":"18","author":"Wang","year":"2016","journal-title":"Europace"},{"key":"key20200713162422_b52-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"2324","DOI":"10.1002\/pmic.201200455","article-title":"Pilot study identifying myosin heavy chain 7, desmin, insulin-like growth factor 7, and annexin A2 as circulating biomarkers of human heart failure","volume":"13","author":"Chugh","year":"2013","journal-title":"Proteomics"},{"key":"key20200713162422_b53-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1172\/JCI112713","article-title":"Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo","volume":"78","author":"Ginsberg","year":"1986","journal-title":"J Clin Invest"},{"key":"key20200713162422_b54-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1042\/CS20070308","article-title":"Apolipoprotein C-III: Understanding an emerging cardiovascular risk factor","volume":"114","author":"Ooi","year":"2008","journal-title":"Clin Sci (Lond)"},{"key":"key20200713162422_b55-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1161\/01.ATV.15.7.963","article-title":"Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E","volume":"15","author":"Clavey","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key20200713162422_b56-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.jacl.2015.05.002","article-title":"The risk of cardiovascular events with increased apolipoprotein CIII: A systematic review and meta-analysis","volume":"9","author":"Wyler von Ballmoos","year":"2015","journal-title":"J Clin Lipidol"},{"key":"key20200713162422_b57-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1056\/NEJMoa1308027","article-title":"Loss-of-function mutations in APOC3 and risk of ischemic vascular disease","volume":"371","author":"Jorgensen","year":"2014","journal-title":"N Engl J Med"},{"key":"key20200713162422_b58-ijmm-45-03-0793","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1186\/s12944-016-0352-y","article-title":"The emerging role of apolipoprotein C-III: Beyond effects on triglyceride metabolism","volume":"15","author":"Luo","year":"2016","journal-title":"Lipids Health Dis"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T15:50:47Z","timestamp":1594655447000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2020.4472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,22]]},"references-count":58,"URL":"https:\/\/doi.org\/10.3892\/ijmm.2020.4472","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,22]]}}}