{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T18:37:24Z","timestamp":1751481444976},"reference-count":37,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Mol Med"],"DOI":"10.3892\/ijmm.2020.4517","type":"journal-article","created":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T13:34:32Z","timestamp":1582724072000},"source":"Crossref","is-referenced-by-count":7,"title":["Pigment epithelium\u2011derived factor facilitates NLRP3 inflammasome activation through downregulating cytidine monophosphate kinase 2: A potential treatment strategy for missed abortion"],"prefix":"10.3892","author":[{"given":"Xi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Changning Maternity and Infant Health Hospital, Shanghai 200050, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Changning Maternity and Infant Health Hospital, Shanghai 200050, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2020,2,26]]},"reference":[{"key":"key20200713162549_b1-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1038\/s41598-017-01892-0","article-title":"Misoprostol for medical treatment of missed abortion: A systematic review and network meta-analysis","volume":"7","author":"Wu","year":"2017","journal-title":"Sci Rep"},{"key":"key20200713162549_b2-ijmm-45-05-1436","first-page":"563","article-title":"Medical management of missed abortion: A randomized clinical trial","volume":"99","author":"Wood","year":"2002","journal-title":"Obstet Gynecol"},{"key":"key20200713162549_b3-ijmm-45-05-1436","first-page":"175","article-title":"Induced abortion operations and their early sequelae. Joint study of the Royal College of General Practitioners and the Royal College of Obstetricians and Gynaecologists","volume":"35","year":"1985","journal-title":"J R Coll Gen Pract"},{"key":"key20200713162549_b4-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1080\/01443610120113382","article-title":"Medical termination of missed abortion","volume":"22","author":"Chia","year":"2002","journal-title":"J Obstet Gynaecol"},{"key":"key20200713162549_b5-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/j.1471-0528.2006.00998.x","article-title":"Economic evaluation of alternative management methods of first-trimester miscarriage based on results from the MIST trial","volume":"113","author":"Petrou","year":"2006","journal-title":"BJOG"},{"key":"key20200713162549_b6-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3892\/etm.2013.1422","article-title":"CD4+CD25+FoxP3+ regulatory T cells and cytokines interact with estradiol in cases of missed abortion","volume":"7","author":"Cao","year":"2014","journal-title":"Exp Ther Med"},{"key":"key20200713162549_b7-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1080\/13625187.2019.1569224","article-title":"Sublingual vs vaginal misoprostol for completion of first trimester missed abortion: A randomised controlled trial","volume":"24","author":"Abdelshafy","year":"2019","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"key20200713162549_b8-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1059 e1013","DOI":"10.1016\/j.fertnstert.2005.09.059","article-title":"Aneuploidy screening in a coelomic sample from a missed abortion using sequential fluorescence in situ hybridization","volume":"85","author":"Chatzimeletiou","year":"2006","journal-title":"Fertil Steril"},{"key":"key20200713162549_b9-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1136\/bmj.305.6866.1399","article-title":"Medical management of missed abortion and anembryonic pregnancy","volume":"305","author":"el-Refaey","year":"1992","journal-title":"BMJ"},{"key":"key20200713162549_b10-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.cell.2010.01.040","article-title":"The inflammasomes","volume":"140","author":"Schroder","year":"2010","journal-title":"Cell"},{"key":"key20200713162549_b11-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1126\/science.1184003","article-title":"The NLRP3 inflammasome: A sensor for metabolic danger?","volume":"327","author":"Schroder","year":"2010","journal-title":"Science"},{"key":"key20200713162549_b12-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"e1005973","DOI":"10.1371\/journal.ppat.1005973","article-title":"IL-1\u03b2\/IL-6\/CRP and IL-18\/ferritin: Distinct inflammatory programs in infections","volume":"12","author":"Slaats","year":"2016","journal-title":"PLoS Pathog"},{"key":"key20200713162549_b13-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1038\/s41586-018-0372-z","article-title":"New mitochondrial DNA synthesis enables NLRP3 inflammasome activation","volume":"560","author":"Zhong","year":"2018","journal-title":"Nature"},{"key":"key20200713162549_b14-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1042\/CS20130463","article-title":"PEDF and its roles in physiological and pathological conditions: Implication in diabetic and hypoxia-induced angiogenic diseases","volume":"128","author":"He","year":"2015","journal-title":"Clin Sci (Lond)"},{"key":"key20200713162549_b15-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1080\/14767058.2017.1335707","article-title":"Pigment epithelial-derived factor in human fetal membranes","volume":"31","author":"Stalberg","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"key20200713162549_b16-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s10456-016-9513-x","article-title":"Pigment epithelium-derived factor (PEDF): A novel trophoblast-derived factor limiting feto-placental angiogenesis in late pregnancy","volume":"19","author":"Loegl","year":"2016","journal-title":"Angiogenesis"},{"key":"key20200713162549_b17-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"E2064","DOI":"10.3390\/ijms17122064","article-title":"PEDF inhibits the activation of NLRP3 inflammasome in hypoxia cardiomyocytes through PEDF receptor\/phospholipase A2","volume":"17","author":"Zhou","year":"2016","journal-title":"Int J Mol Sci"},{"key":"key20200713162549_b18-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/978-1-62703-715-0_7","article-title":"The polymerase chain reaction (PCR): General methods","volume":"1099","author":"Waters","year":"2014","journal-title":"Methods Mol Biol"},{"key":"key20200713162549_b19-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1038\/ni.1980","article-title":"Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome","volume":"12","author":"Nakahira","year":"2011","journal-title":"Nat Immunol"},{"key":"key20200713162549_b20-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"2770","DOI":"10.1073\/pnas.0807694106","article-title":"Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling","volume":"106","author":"Tal","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713162549_b21-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1016\/j.bbabio.2009.06.009","article-title":"Mitochondrial calcium and the permeability transition in cell death","volume":"1787","author":"Lemasters","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"key20200713162549_b22-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.fertnstert.2014.10.012","article-title":"Expression of GRIM-19 in missed abortion and possible pathogenesis","volume":"103","author":"Chen","year":"2015","journal-title":"Fertil Steril"},{"key":"key20200713162549_b23-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s00404-018-4802-9","article-title":"Early missed abortion is associated with villous angiogenesis via the HIF-1alpha\/VEGF signaling pathway","volume":"298","author":"Zhi","year":"2018","journal-title":"Arch Gynecol Obstet"},{"issue":"Suppl A","key":"key20200713162549_b24-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"A31","DOI":"10.1253\/circj.CJ-08-0014","article-title":"Oxidative stress and mitochondrial DNA damage in heart failure","volume":"72","author":"Tsutsui","year":"2008","journal-title":"Circ J"},{"key":"key20200713162549_b25-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"2539","DOI":"10.1093\/nar\/gkp100","article-title":"Oxidative stress induces degradation of mitochondrial DNA","volume":"37","author":"Shokolenko","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"key20200713162549_b26-ijmm-45-05-1436","first-page":"1","article-title":"Emerging views of mitophagy in immunity and autoimmune diseases","author":"Xu","year":"2019","journal-title":"Autophagy"},{"key":"key20200713162549_b27-ijmm-45-05-1436","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.1839","article-title":"Measurement of Mitochondrial DNA Release in Response to ER Stress","volume":"6","author":"Bronner","year":"2016","journal-title":"Bio Protoc"},{"issue":"Suppl 1","key":"key20200713162549_b28-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1186\/1471-2091-9-S1-S7","article-title":"The ubiquitin system, disease, and drug discovery","volume":"9","author":"Petroski","year":"2008","journal-title":"BMC Biochem"},{"key":"key20200713162549_b29-ijmm-45-05-1436","first-page":"1243","article-title":"Management of spontaneous abortion","volume":"72","author":"Griebel","year":"2005","journal-title":"Am Fam Physician"},{"key":"key20200713162549_b30-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1097\/GRF.0b013e31802f1233","article-title":"Contemporary management of early pregnancy failure","volume":"50","author":"Chen","year":"2007","journal-title":"Clin Obstet Gynecol"},{"key":"key20200713162549_b31-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1093\/humrep\/dep044","article-title":"MDM2309 polymorphism is associated with missed abortion","volume":"24","author":"Fang","year":"2009","journal-title":"Hum Reprod"},{"key":"key20200713162549_b32-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1111\/j.1600-065X.2011.01046.x","article-title":"The inflammasome: An integrated view","volume":"243","author":"Gross","year":"2011","journal-title":"Immunol Rev"},{"key":"key20200713162549_b33-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/j.cell.2015.02.010","article-title":"Homeostasis, inflammation, and disease susceptibility","volume":"160","author":"Kotas","year":"2015","journal-title":"Cell"},{"key":"key20200713162549_b34-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1016\/j.cell.2014.02.008","article-title":"Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes","volume":"156","author":"Lu","year":"2014","journal-title":"Cell"},{"key":"key20200713162549_b35-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.cyto.2011.04.010","article-title":"PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor\/phospholipase A2 and regulation of NFkappaB and PPARgamma","volume":"55","author":"Hirsch","year":"2011","journal-title":"Cytokine"},{"key":"key20200713162549_b36-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1038\/ijo.2012.223","article-title":"Liver, but not adipose tissue PEDF gene expression is associated with insulin resistance","volume":"37","author":"Moreno-Navarrete","year":"2013","journal-title":"Int J Obes (Lond)"},{"key":"key20200713162549_b37-ijmm-45-05-1436","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/j.bbrc.2013.12.060","article-title":"Laminin receptor mediates anti-inflammatory and anti-thrombogenic effects of pigment epithelium-derived factor in myeloma cells","volume":"443","author":"Matsui","year":"2014","journal-title":"Biochem Biophys Res Commun"}],"container-title":["International Journal of Molecular Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T16:16:00Z","timestamp":1594656960000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijmm.2020.4517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,26]]},"references-count":37,"URL":"https:\/\/doi.org\/10.3892\/ijmm.2020.4517","relation":{},"ISSN":["1107-3756","1791-244X"],"issn-type":[{"value":"1107-3756","type":"print"},{"value":"1791-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,26]]}}}