{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:37:54Z","timestamp":1789706274346,"version":"4.0.1"},"reference-count":47,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.3892\/ijo.2017.3991","type":"journal-article","created":{"date-parts":[[2017,5,9]],"date-time":"2017-05-09T08:51:26Z","timestamp":1494319886000},"page":"2024-2032","source":"Crossref","is-referenced-by-count":6,"title":["Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure"],"prefix":"10.3892","volume":"50","author":[{"given":"Megumi","family":"Maeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suni","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Kumagai-Takei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Yoshitome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenori","family":"Matsuzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamayo","family":"Hatayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasumitsu","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takemi","family":"Otsuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2017,5,9]]},"reference":[{"key":"key20180107180216_b1-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/00063198-200003000-00010","article-title":"Pathology and pathophysiology of pneumoconiosis","volume":"6","author":"Fujimura","year":"2000","journal-title":"Curr Opin Pulm Med"},{"key":"key20180107180216_b2-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1164\/ajrccm.157.5.9707141","article-title":"Mechanisms in the pathogenesis of asbestosis and silicosis","volume":"157","author":"Mossman","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"key20180107180216_b3-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ccm.2015.02.008","article-title":"Occupational and environmental lung disease","volume":"36","author":"Seaman","year":"2015","journal-title":"Clin Chest Med"},{"key":"key20180107180216_b4-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"9035","DOI":"10.1073\/pnas.0803933105","article-title":"The Nalp3 inflammasome is essential for the development of silicosis","volume":"105","author":"Cassel","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180107180216_b5-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1126\/science.1156995","article-title":"Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica","volume":"320","author":"Dostert","year":"2008","journal-title":"Science"},{"key":"key20180107180216_b6-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/ni.1631","article-title":"Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization","volume":"9","author":"Hornung","year":"2008","journal-title":"Nat Immunol"},{"key":"key20180107180216_b7-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1177\/039463200902200304","article-title":"Impairment in cytotoxicity and expression of NK cell- activating receptors on human NK cells following exposure to asbestos fibers","volume":"22","author":"Nishimura","year":"2009","journal-title":"Int J Immunopathol Pharmacol"},{"key":"key20180107180216_b8-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1177\/039463200902200403","article-title":"Decrease in phosphorylation of ERK following decreased expression of NK cell-activating receptors in human NK cell line exposed to asbestos","volume":"22","author":"Nishimura","year":"2009","journal-title":"Int J Immunopathol Pharmacol"},{"key":"key20180107180216_b9-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s12199-013-0333-y","article-title":"Altered functions of alveolar macrophages and NK cells involved in asbestos-related diseases","volume":"18","author":"Nishimura","year":"2013","journal-title":"Environ Health Prev Med"},{"key":"key20180107180216_b10-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1165\/rcmb.2012-0134OC","article-title":"Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in mixed lymphocyte reaction of human peripheral blood mononuclear cells","volume":"49","author":"Kumagai-Takei","year":"2013","journal-title":"Am J Respir Cell Mol Biol"},{"key":"key20180107180216_b11-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"670140","DOI":"10.1155\/2014\/670140","article-title":"Functional properties of CD8(+) lymphocytes in patients with pleural plaque and malignant mesothelioma","volume":"2014","author":"Kumagai-Takei","year":"2014","journal-title":"J Immunol Res"},{"key":"key20180107180216_b12-ijo-50-06-2024","first-page":"211","article-title":"Effects of asbestos fibers on human cytotoxic T cells","volume-title":"Biological Effects of Fibrous and Particulate Substances (Series Title: Current Topics in Environmental Health and Preventive Medicine)","author":"Kumagai-Takei","year":"2015"},{"key":"key20180107180216_b13-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"7484872","DOI":"10.1155\/2016\/7484872","article-title":"The suppressed induction of human mature cytotoxic T lymphocytes caused by asbestos is not due to Interleukin-2 insufficiency","volume":"2016","author":"Kumagai-Takei","year":"2016","journal-title":"J Immunol Res"},{"key":"key20180107180216_b14-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-3083.2005.01592.x","article-title":"Inhibitory effects of anti-oxidants on apoptosis of a human poly-clonal T-cell line, MT-2, induced by an asbestos, chrysotile-A","volume":"61","author":"Hyodoh","year":"2005","journal-title":"Scand J Immunol"},{"key":"key20180107180216_b15-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1007\/s10495-006-9235-4","article-title":"Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cells","volume":"11","author":"Miura","year":"2006","journal-title":"Apoptosis"},{"key":"key20180107180216_b16-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.imbio.2013.04.007","article-title":"Alteration of cytoskeletal molecules in a human T cell line caused by continuous exposure to chrysotile asbestos","volume":"218","author":"Maeda","year":"2013","journal-title":"Immunobiology"},{"key":"key20180107180216_b17-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1165\/rcmb.2010-0213OC","article-title":"Reduction of CXC chemokine receptor 3 in an in vitro model of continuous exposure to asbestos in a human T-cell line, MT-2","volume":"45","author":"Maeda","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"key":"key20180107180216_b18-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1165\/rcmb.2010-0435OC","article-title":"Decreased CXCR3 expression in CD4+ T cells exposed to asbestos or derived from asbestos-exposed patients","volume":"45","author":"Maeda","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"key":"key20180107180216_b19-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"481439","DOI":"10.1155\/2011\/481439","article-title":"Asbestos induces reduction of tumor immunity","volume":"2011","author":"Kumagai-Takei","year":"2011","journal-title":"Clin Dev Immunol"},{"key":"key20180107180216_b20-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"492608","DOI":"10.1155\/2012\/492608","article-title":"Asbestos-induced cellular and molecular alteration of immunocompetent cells and their relationship with chronic inflammation and carcinogenesis","volume":"2012","author":"Matsuzaki","year":"2012","journal-title":"J Biomed Biotechnol"},{"key":"key20180107180216_b21-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s12199-015-0499-6","article-title":"Environmental factors and human health: Fibrous and particulate substance-induced immunological disorders and construction of a health-promoting living environment","volume":"21","author":"Otsuki","year":"2016","journal-title":"Environ Health Prev Med"},{"key":"key20180107180216_b22-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1093\/acprof:oso\/9780195178692.003.0009","article-title":"Nonthoracic cancers possibly resulting from asbestos exposure","volume-title":"Asbestos and its Diseases","author":"Craighead","year":"2008"},{"key":"key20180107180216_b23-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1201\/b10958-14","article-title":"Malignant diseases attributed to asbestos exposure","volume-title":"Asbestos. Risk assessment, epidemiology, and health effects","author":"Freidman","year":"2011"},{"key":"key20180107180216_b24-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"957878","DOI":"10.1155\/2013\/957878","article-title":"The multifaceted role of Th17 lymphocytes and their associated cytokines in cancer","volume":"2013","author":"Alizadeh","year":"2013","journal-title":"Clin Dev Immunol"},{"key":"key20180107180216_b25-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3389\/fimmu.2014.00276","article-title":"Th17 cells in cancer: The ultimate identity crisis","volume":"5","author":"Bailey","year":"2014","journal-title":"Front Immunol"},{"key":"key20180107180216_b26-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00011-013-0645-9","article-title":"Immune system: A double-edged sword in cancer","volume":"62","author":"Lakshmi Narendra","year":"2013","journal-title":"Inflamm Res"},{"key":"key20180107180216_b27-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nri2742","article-title":"T(H)17 cells in tumour immunity and immunotherapy","volume":"10","author":"Zou","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"key20180107180216_b28-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/1547691X.2013.847510","article-title":"Amphibole, but not chrysotile, asbestos induces anti-nuclear autoantibodies and IL-17 in C57BL\/6 mice","volume":"11","author":"Ferro","year":"2014","journal-title":"J Immunotoxicol"},{"key":"key20180107180216_b29-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"774","DOI":"10.3109\/08958378.2013.848249","article-title":"Asbestos-associated mesothelial cell autoantibodies promote collagen deposition in vitro","volume":"25","author":"Serve","year":"2013","journal-title":"Inhal Toxicol"},{"key":"key20180107180216_b30-ijo-50-06-2024","first-page":"782045","article-title":"Autoimmunity and asbestos exposure","volume":"2014","author":"Pfau","year":"2014","journal-title":"Autoimmune Dis"},{"key":"key20180107180216_b31-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.taap.2014.01.018","article-title":"Erionite induces production of autoantibodies and IL-17 in C57BL\/6 mice","volume":"275","author":"Zebedeo","year":"2014","journal-title":"Toxicol Appl Pharmacol"},{"key":"key20180107180216_b32-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.scitotenv.2012.04.043","article-title":"Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite on a human T cell","volume":"429","author":"Maeda","year":"2012","journal-title":"Sci Total Environ"},{"key":"key20180107180216_b33-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/10937404.2011.556051","article-title":"Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases","volume":"14","author":"Huang","year":"2011","journal-title":"J Toxicol Environ Health B Crit Rev"},{"key":"key20180107180216_b34-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0013-9351(81)90028-1","article-title":"Mechanisms of asbestos carcinogenesis","volume":"25","author":"Mossman","year":"1981","journal-title":"Environ Res"},{"issue":"Suppl 10","key":"key20180107180216_b35-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1289\/ehp.94102s10131","article-title":"Oxygen radicals and asbestos carcinogenesis","volume":"102","author":"Moyer","year":"1994","journal-title":"Environ Health Perspect"},{"key":"key20180107180216_b36-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1179\/1351000213Y.0000000075","article-title":"Iron overload as a major targetable pathogenesis of asbestos-induced mesothelial carcinogenesis","volume":"19","author":"Toyokuni","year":"2014","journal-title":"Redox Rep"},{"key":"key20180107180216_b37-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/nm.3947","article-title":"Loss of BAP1 function leads to EZH2-dependent transformation","volume":"21","author":"LaFave","year":"2015","journal-title":"Nat Med"},{"key":"key20180107180216_b38-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1093\/carcin\/bgt166","article-title":"Molecular pathogenesis of malignant mesothelioma","volume":"34","author":"Sekido","year":"2013","journal-title":"Carcinogenesis"},{"key":"key20180107180216_b39-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/modpathol.2015.121","article-title":"The prognostic significance of BAP1, NF2, and CDKN2A in malignant peritoneal mesothelioma","volume":"29","author":"Singhi","year":"2016","journal-title":"Mod Pathol"},{"key":"key20180107180216_b40-ijo-50-06-2024","first-page":"195","article-title":"T cell alteration caused by exposure to asbestos","volume-title":"Biological Effects of Fibrous and Particulate Substances, (Series Title: Current Topics in Environmental Health and Preventive Medicine)","author":"Maeda","year":"2015"},{"key":"key20180107180216_b41-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1365-2249.2009.04040.x","article-title":"Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation","volume":"159","author":"O'Connor","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"key20180107180216_b42-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1007\/s12265-013-9496-6","article-title":"T helper cell polarization in healthy people: Implications for cardiovascular disease","volume":"6","author":"Olson","year":"2013","journal-title":"J Cardiovasc Transl Res"},{"key":"key20180107180216_b43-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.tox.2015.10.005","article-title":"Enhancement of regulatory T cell-like suppressive function in MT-2 by long-term and low-dose exposure to asbestos","volume":"338","author":"Ying","year":"2015","journal-title":"Toxicology"},{"key":"key20180107180216_b44-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3892\/ijo.2016.3776","article-title":"Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers","volume":"50","author":"Lee","year":"2017","journal-title":"Int J Oncol"},{"key":"key20180107180216_b45-ijo-50-06-2024","first-page":"613","article-title":"The mechanisms of vitamin K2-induced apoptosis of myeloma cells","volume":"91","author":"Tsujioka","year":"2006","journal-title":"Haematologica"},{"key":"key20180107180216_b46-ijo-50-06-2024","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1365-2141.2004.05205.x","article-title":"Expression of protein gene product 9.5 (PGP9.5)\/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells","volume":"127","author":"Otsuki","year":"2004","journal-title":"Br J Haematol"},{"key":"key20180107180216_b47-ijo-50-06-2024","first-page":"1434","article-title":"Estrogen receptors in human myeloma cells","volume":"60","author":"Otsuki","year":"2000","journal-title":"Cancer Res"}],"container-title":["International Journal of Oncology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T18:02:51Z","timestamp":1515348171000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ijo.2017.3991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,9]]},"references-count":47,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,5,9]]},"published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.3892\/ijo.2017.3991"],"URL":"https:\/\/doi.org\/10.3892\/ijo.2017.3991","relation":{},"ISSN":["1019-6439","1791-2423"],"issn-type":[{"value":"1019-6439","type":"print"},{"value":"1791-2423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,9]]}}}