{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T16:47:52Z","timestamp":1780505272017,"version":"3.54.1"},"reference-count":41,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Oncol"],"DOI":"10.3892\/ijo.2018.4366","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T06:39:41Z","timestamp":1523515181000},"source":"Crossref","is-referenced-by-count":6,"title":["Differences between carcinoma of the cecum and ascending colon: Evidence based on clinical and embryological data"],"prefix":"10.3892","author":[{"given":"Xin","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhangjian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongchun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengxue","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2018,4,12]]},"reference":[{"key":"key20200713184827_b1-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"key20200713184827_b2-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21387","article-title":"Cancer Statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"key20200713184827_b3-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1002\/jso.20156","article-title":"Two colons-two cancers: Paradigm shift and clinical implications","volume":"88","author":"Gervaz","year":"2004","journal-title":"J Surg Oncol"},{"key":"key20200713184827_b4-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"157","DOI":"10.5114\/aoms.2016.58596","article-title":"Right- and left-sided colon cancer - clinical and pathological differences of the disease entity in one organ","volume":"13","author":"Mik","year":"2017","journal-title":"Arch Med Sci"},{"key":"key20200713184827_b5-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s12079-017-0381-y","article-title":"What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers?","volume":"11","author":"Trosko","year":"2017","journal-title":"J Cell Commun Signal"},{"key":"key20200713184827_b6-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"e002608","DOI":"10.1136\/bmjopen-2013-002608","article-title":"A nationwide Danish cohort study challenging the categorisation into right-sided and left-sided colon cancer","volume":"3","author":"Jess","year":"2013","journal-title":"BMJ Open"},{"key":"key20200713184827_b7-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.ejso.2010.12.004","article-title":"Colon carcinoma - classification into right and left sided cancer or according to colonic subsite? - Analysis of 29,568 patients","volume":"37","author":"Benedix","year":"2011","journal-title":"Eur J Surg Oncol"},{"key":"key20200713184827_b8-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1007\/s11605-015-3026-6","article-title":"The worse prognosis of right-sided compared with left-sided colon cancers: A systematic review and meta-analysis","volume":"20","author":"Yahagi","year":"2016","journal-title":"J Gastrointest Surg"},{"key":"key20200713184827_b9-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.1016\/j.clcc.2016.02.007","article-title":"Impact of primary tumor site on bevacizumab efficacy in metastatic colorectal cancer","volume":"15","author":"Wong","year":"2016","journal-title":"Clin Colorectal Cancer"},{"key":"key20200713184827_b10-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"406","DOI":"10.5858\/arpa.2015-0310-RA","article-title":"Molecular subtypes of colorectal cancer and their clinicopathologic features, with an emphasis on the serrated neoplasia pathway","volume":"140","author":"Bae","year":"2016","journal-title":"Arch Pathol Lab Med"},{"key":"key20200713184827_b11-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1136\/gutjnl-2011-300865","article-title":"Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum","volume":"61","author":"Yamauchi","year":"2012","journal-title":"Gut"},{"key":"key20200713184827_b12-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212\u0394 \u0394 C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20200713184827_b13-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"7","DOI":"10.21037\/atm.2016.08.57","article-title":"Propensity score method: A non-parametric technique to reduce model dependence","volume":"5","author":"Zhang","year":"2017","journal-title":"Ann Transl Med"},{"key":"key20200713184827_b14-ijo-53-01-0087","unstructured":"Network NCC(NCCN)Clinical Practice Guidelines in Oncology. Colon Cancer, Version 22017https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/colon.pdf. Accessed March 13, 2017"},{"issue":"5S","key":"key20200713184827_b15-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"699","DOI":"10.6004\/jnccn.2017.0077","article-title":"Systemic management of colorectal cancer","volume":"15","author":"Messersmith","year":"2017","journal-title":"J Natl Compr Canc Netw"},{"key":"key20200713184827_b16-ijo-53-01-0087","volume-title":"Core Textbook of Anatomy","author":"Thompson","year":"1977","edition":"1st edition"},{"key":"key20200713184827_b17-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/S0140-6736(03)12489-0","article-title":"Gut flora in health and disease","volume":"361","author":"Guarner","year":"2003","journal-title":"Lancet"},{"key":"key20200713184827_b18-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/S0749-0739(17)30241-9","article-title":"Diseases and surgery of the cecum","volume":"13","author":"Dabareiner","year":"1997","journal-title":"Vet Clin North Am Equine Pract"},{"key":"key20200713184827_b19-ijo-53-01-0087","first-page":"728579","article-title":"Cancers of the appendix: Review of the literatures","volume":"2011","author":"Ruoff","year":"2011","journal-title":"ISRN Oncol"},{"key":"key20200713184827_b20-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1002\/cncr.29129","article-title":"Does the primary site of colorectal cancer impact outcomes for patients with metastatic disease?","volume":"121","author":"Price","year":"2015","journal-title":"Cancer"},{"key":"key20200713184827_b21-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"dju427","DOI":"10.1093\/jnci\/dju427","article-title":"Primary tumor location as a prognostic factor in metastatic colorectal cancer","volume":"107","author":"Loupakis","year":"2015","journal-title":"J Natl Cancer Inst"},{"key":"key20200713184827_b22-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"388","DOI":"10.7150\/jca.16804","article-title":"Primary tumor location as a predictive factor for first-line bevacizumab effectiveness in metastatic colorectal cancer patients","volume":"8","author":"He","year":"2017","journal-title":"J Cancer"},{"key":"key20200713184827_b23-ijo-53-01-0087","article-title":"Prognostic and predictive relevance of primary tumor location in patients with RAS wild-type metastatic colorectal cancer: Retrospective analyses of the CRYSTAL and FIRE-3 trials","author":"Tejpar","year":"2016","journal-title":"JAMA Oncol"},{"key":"key20200713184827_b24-ijo-53-01-0087","first-page":"48","article-title":"The ASCRS Textbook of Colon and Rectal Surgery","volume":"7","author":"Timmcke","year":"2007","journal-title":"Ochsner J"},{"key":"key20200713184827_b25-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.jfma.2017.03.012","article-title":"The incidence and clinical associated factors of interval colorectal cancers in Southern Taiwan","volume":"117","author":"Tsai","year":"2018","journal-title":"J Formos Med Assoc"},{"key":"key20200713184827_b26-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1001\/jama.2011.1285","article-title":"Association between lymph node evaluation for colon cancer and node positivity over the past 20 years","volume":"306","author":"Parsons","year":"2011","journal-title":"JAMA"},{"key":"key20200713184827_b27-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"59945","DOI":"10.18632\/oncotarget.11007","article-title":"Whether regional lymph nodes evaluation should be equally required for both right and left colon cancer","volume":"7","author":"Guan","year":"2016","journal-title":"Oncotarget"},{"key":"key20200713184827_b28-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"6470","DOI":"10.3748\/wjg.v21.i21.6470","article-title":"Different treatment strategies and molecular features between right-sided and left-sided colon cancers","volume":"21","author":"Shen","year":"2015","journal-title":"World J Gastroenterol"},{"key":"key20200713184827_b29-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"3381","DOI":"10.1200\/JCO.2010.34.3426","article-title":"Adjuvant chemotherapy for stage II colon cancer with poor prognostic features","volume":"29","author":"O'Connor","year":"2011","journal-title":"J Clin Oncol"},{"key":"key20200713184827_b30-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"38901","DOI":"10.1038\/srep38901","article-title":"Exploration of the optimal minimum lymph node count after colon cancer resection for patients aged 80 years and older","volume":"6","author":"Guan","year":"2016","journal-title":"Sci Rep"},{"key":"key20200713184827_b31-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1080\/00365520701677755","article-title":"Location of liver metastases reflects the site of the primary colorectal carcinoma","volume":"43","author":"Konopke","year":"2008","journal-title":"Scand J Gastroenterol"},{"key":"key20200713184827_b32-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1097\/00003072-198508000-00006","article-title":"'Streaming' in portal vein. Its effect on the spread of metastases to the liver","volume":"10","author":"Desai","year":"1985","journal-title":"Clin Nucl Med"},{"key":"key20200713184827_b33-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"23161","DOI":"10.1074\/jbc.M001448200","article-title":"Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide","volume":"275","author":"K\u00f6nig","year":"2000","journal-title":"J Biol Chem"},{"key":"key20200713184827_b34-ijo-53-01-0087","doi-asserted-by":"publisher","DOI":"10.1177\/1010428317691176","article-title":"SLCO1B3 screening in colorectal cancer patients using High-Resolution Melting Analysis method and immunohistochemistry","volume":"39","author":"Evangeli","year":"2017","journal-title":"Tumour Biol"},{"key":"key20200713184827_b35-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1053\/gast.2001.21176","article-title":"Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver","volume":"120","author":"Kullak-Ublick","year":"2001","journal-title":"Gastroenterology"},{"key":"key20200713184827_b36-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1093\/toxsci\/kfj141","article-title":"Molecular characterization and inhibition of amanitin uptake into human hepatocytes","volume":"91","author":"Letschert","year":"2006","journal-title":"Toxicol Sci"},{"key":"key20200713184827_b37-ijo-53-01-0087","first-page":"27","article-title":"Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets","volume":"4","author":"Kounnis","year":"2011","journal-title":"Onco Targets Ther"},{"key":"key20200713184827_b38-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"10315","DOI":"10.1158\/0008-5472.CAN-08-1984","article-title":"Overexpression of OATP1B3 confers apoptotic resistance in colon cancer","volume":"68","author":"Lee","year":"2008","journal-title":"Cancer Res"},{"key":"key20200713184827_b39-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2147\/CEG.S3743","article-title":"Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome","volume":"1","author":"Lockhart","year":"2008","journal-title":"Clin Exp Gastroenterol"},{"key":"key20200713184827_b40-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.jcmgh.2017.01.006","article-title":"Colorectal cancer liver metastasis: Evolving paradigms and future directions","volume":"3","author":"Zarour","year":"2017","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"key20200713184827_b41-ijo-53-01-0087","doi-asserted-by":"publisher","first-page":"324","DOI":"10.3892\/ijo.2014.2731","article-title":"The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells","volume":"46","author":"Brenner","year":"2015","journal-title":"Int J Oncol"}],"container-title":["International Journal of Oncology"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T18:58:09Z","timestamp":1594666689000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijo.2018.4366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,12]]},"references-count":41,"URL":"https:\/\/doi.org\/10.3892\/ijo.2018.4366","relation":{},"ISSN":["1019-6439","1791-2423"],"issn-type":[{"value":"1019-6439","type":"print"},{"value":"1791-2423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,12]]}}}