{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T04:11:36Z","timestamp":1751602296906,"version":"3.41.0"},"reference-count":25,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Oncol"],"DOI":"10.3892\/ijo.2018.4373","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T08:54:05Z","timestamp":1523868845000},"source":"Crossref","is-referenced-by-count":4,"title":["Antitumoral effect of Ocoxin, a natural compound-containing nutritional supplement, in small cell lung cancer"],"prefix":"10.3892","author":[{"given":"Elena","family":"D\u00ef\u00bf\u00bdaz-Rodr\u00ef\u00bf\u00bdguez","sequence":"first","affiliation":[{"name":"Institute of Molecular and Cellular Cancer Biology, Cancer Research Institute of Salamanca (CSIC), 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Sanz","sequence":"additional","affiliation":[{"name":"Catalysis, S.L., 28016 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atanasio","family":"Pandiella","sequence":"additional","affiliation":[{"name":"Institute of Molecular and Cellular Cancer Biology, Cancer Research Institute of Salamanca (CSIC), 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"key":"key20200713184830_b1-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.lungcan.2011.08.004","article-title":"Trends in incidence of small cell lung cancer and all lung cancer","volume":"75","author":"Riaz","year":"2012","journal-title":"Lung Cancer"},{"key":"key20200713184830_b2-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"key20200713184830_b3-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"4539","DOI":"10.1200\/JCO.2005.04.4859","article-title":"Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database","volume":"24","author":"Govindan","year":"2006","journal-title":"J Clin Oncol"},{"key":"key20200713184830_b4-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.cllc.2016.05.014","article-title":"SCLC-state of the art and what does the future have in store?","volume":"17","author":"Kahnert","year":"2016","journal-title":"Clin Lung Cancer"},{"key":"key20200713184830_b5-ijo-53-01-0113","first-page":"304","article-title":"Antioxidants in cancer therapy; their actions and interactions with oncologic therapies","volume":"4","author":"Lamson","year":"1999","journal-title":"Altern Med Rev"},{"issue":"Suppl 2","key":"key20200713184830_b6-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"472S","DOI":"10.1093\/jn\/130.2.472S","article-title":"Tea and tea polyphenols in cancer prevention","volume":"130","author":"Yang","year":"2000","journal-title":"J Nutr"},{"key":"key20200713184830_b7-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1002\/tcr.20039","article-title":"Green tea: Health benefits as cancer preventive for humans","volume":"5","author":"Fujiki","year":"2005","journal-title":"Chem Rec"},{"key":"key20200713184830_b8-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1002\/mnfr.200500135","article-title":"Chemoprevention of lung cancer by tea","volume":"50","author":"Clark","year":"2006","journal-title":"Mol Nutr Food Res"},{"key":"key20200713184830_b9-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.canlet.2015.01.038","article-title":"Dietary agents for prevention and treatment of lung cancer","volume":"359","author":"Khan","year":"2015","journal-title":"Cancer Lett"},{"key":"key20200713184830_b10-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1093\/ecam\/nel066","article-title":"Does the consumption of green tea reduce the risk of lung cancer among smokers?","volume":"4","author":"Liang","year":"2007","journal-title":"Evid Based Complement Alternat Med"},{"key":"key20200713184830_b11-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"1956","DOI":"10.1158\/0008-5472.CAN-05-3158","article-title":"A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice","volume":"66","author":"Lu","year":"2006","journal-title":"Cancer Res"},{"key":"key20200713184830_b12-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.bbrc.2007.06.030","article-title":"The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells","volume":"360","author":"Sadava","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"key20200713184830_b13-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1080\/01635581.2015.1068819","article-title":"Effect of oncoxin oral solution in HER2-overexpressing breast cancer","volume":"67","author":"Hern\u00e1ndez-Garc\u00eda","year":"2015","journal-title":"Nutr Cancer"},{"key":"key20200713184830_b14-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"198","DOI":"10.3181\/00379727-220-44365","article-title":"Tea flavonols in cardiovascular disease and cancer epidemiology","volume":"220","author":"Hollman","year":"1999","journal-title":"Proc Soc Exp Biol Med"},{"key":"key20200713184830_b15-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/ijc.2910620319","article-title":"Cinnamic acid: A natural product with potential use in cancer intervention","volume":"62","author":"Liu","year":"1995","journal-title":"Int J Cancer"},{"key":"key20200713184830_b16-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"2638","DOI":"10.3748\/wjg.v16.i21.2638","article-title":"Antioxidant and immunomodulatory effects of Viusid in patients with chronic hepatitis C","volume":"16","author":"Gomez","year":"2010","journal-title":"World J Gastroenterol"},{"key":"key20200713184830_b17-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"443","DOI":"10.4103\/0019-509X.176699","article-title":"Increased survival of patients with end-stage hepatocellular carcinoma due to intake of ONCOXIN\u00ae, a dietary supplement","volume":"52","author":"Al-Mahtab","year":"2015","journal-title":"Indian J Cancer"},{"key":"key20200713184830_b18-ijo-53-01-0113","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3329\/taj.v22i2.37718","article-title":"Findings of the 3-month supportive treatment with ocoxin solution beside the standard modalities of patients with different neoplastic diseases","volume":"22","author":"Dayem Uddin","year":"2009","journal-title":"TAJ"},{"key":"key20200713184830_b19-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"6231","DOI":"10.18632\/oncotarget.6862","article-title":"Antitumoral effect of ocoxin on acute myeloid leukemia","volume":"7","author":"D\u00edaz-Rodr\u00edguez","year":"2016","journal-title":"Oncotarget"},{"key":"key20200713184830_b20-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"1950","DOI":"10.3892\/ol.2017.6440","article-title":"Antitumoral effect of Ocoxin in hepatocellular carcinoma","volume":"14","author":"D\u00edaz-Rodr\u00edguez","year":"2017","journal-title":"Oncol Lett"},{"key":"key20200713184830_b21-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1111\/j.1349-7006.2003.tb01508.x","article-title":"A naturally occurring p73 mutation in a p73-p53 double-mutant lung cancer cell line encodes p73 alpha protein with a dominant-negative function","volume":"94","author":"Huqun","year":"2003","journal-title":"Cancer Sci"},{"key":"key20200713184830_b22-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/0277-5379(88)90311-2","article-title":"Two small cell lung cancer cell lines established from rigid bronchoscope biopsies","volume":"24","author":"Postmus","year":"1988","journal-title":"Eur J Cancer Clin Oncol"},{"key":"key20200713184830_b23-ijo-53-01-0113","first-page":"3892","article-title":"Voltage-operated calcium channels in small cell lung carcinoma cell lines: Pharmacological, functional, and immunological properties","volume":"50","author":"Sher","year":"1990","journal-title":"Cancer Res"},{"key":"key20200713184830_b24-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1083\/jcb.132.3.427","article-title":"TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment","volume":"132","author":"Cabrera","year":"1996","journal-title":"J Cell Biol"},{"key":"key20200713184830_b25-ijo-53-01-0113","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1038\/nm0195-27","article-title":"Angiogenesis in cancer, vascular, rheumatoid and other disease","volume":"1","author":"Folkman","year":"1995","journal-title":"Nat Med"}],"container-title":["International Journal of Oncology"],"original-title":[],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T17:54:34Z","timestamp":1751565274000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijo.2018.4373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,16]]},"references-count":25,"URL":"https:\/\/doi.org\/10.3892\/ijo.2018.4373","relation":{},"ISSN":["1019-6439","1791-2423"],"issn-type":[{"type":"print","value":"1019-6439"},{"type":"electronic","value":"1791-2423"}],"subject":[],"published":{"date-parts":[[2018,4,16]]}}}