{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T18:28:24Z","timestamp":1648578504035},"reference-count":57,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Oncol"],"DOI":"10.3892\/ijo.2018.4491","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T09:42:56Z","timestamp":1531993376000},"source":"Crossref","is-referenced-by-count":2,"title":["Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling"],"prefix":"10.3892","author":[{"given":"Mohamed","family":"Saeed","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, D-55128 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Mertens","sequence":"additional","affiliation":[{"name":"Section for Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatric and Adolescent Medicine, University Hospital Aachen, D-52047 Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupert","family":"Handgretinger","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology\/Oncology, Children's University Hospital, D-72076 T\ufffdbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Efferth","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, D-55128 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,7,19]]},"reference":[{"key":"key20200713185149_b1-ijo-53-04-1721","first-page":"45","article-title":"Cancer Incidence in Five Continents. Comparability and quality of data","volume":"120","author":"Parkin","year":"1992","journal-title":"IARC Sci Publ"},{"key":"key20200713185149_b2-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"7097","DOI":"10.7314\/APJCP.2015.16.16.7097","article-title":"Declining incidence of nasopharyngeal carcinoma in brunei darussalam: A three decade study (1986-2014)","volume":"16","author":"Chong","year":"2015","journal-title":"Asian Pac J Cancer Prev"},{"key":"key20200713185149_b3-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"E359","DOI":"10.1002\/ijc.29210","article-title":"Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012","volume":"136","author":"Ferlay","year":"2015","journal-title":"Int J Cancer"},{"key":"key20200713185149_b4-ijo-53-04-1721","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0030-6665(20)32347-1","article-title":"Malignant tumors of the head and neck in children: Diagnosis and treatment","volume":"13","author":"Healy","year":"1980","journal-title":"Otolaryngol Clin North Am"},{"key":"key20200713185149_b5-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/0165-5876(87)90109-1","article-title":"Malignant tumors of the head and neck in children: A twenty-year review","volume":"13","author":"Cunningham","year":"1987","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"key20200713185149_b6-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.canep.2013.08.008","article-title":"Racial differences in nasopharyngeal carcinoma in the United States","volume":"37","author":"Wang","year":"2013","journal-title":"Cancer Epidemiol"},{"key":"key20200713185149_b7-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1093\/annonc\/mdf179","article-title":"Nasopharyngeal carcinoma","volume":"13","author":"Chan","year":"2002","journal-title":"Ann Oncol"},{"key":"key20200713185149_b8-ijo-53-04-1721","first-page":"1","volume-title":"Cancer Facts & Figures 2015 Nasopharyngeal Cancer","author":"Society AC","year":"2015"},{"key":"key20200713185149_b9-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1002\/hed.21714","article-title":"High-risk human papillomavirus in nasopharyngeal carcinoma","volume":"34","author":"Singhi","year":"2012","journal-title":"Head Neck"},{"key":"key20200713185149_b10-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1750-9378-8-30","article-title":"Oncogenic human papillomavirus-associated nasopharyngeal carcinoma: An observational study of correlation with ethnicity, histological subtype and outcome in a UK population","volume":"8","author":"Robinson","year":"2013","journal-title":"Infect Agent Cancer"},{"issue":"Suppl 4","key":"key20200713185149_b11-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"S185","DOI":"10.1002\/lary.21649","article-title":"Human papillomavirus & WHO type I nasopharyngeal carcinoma","volume":"120","author":"Lo","year":"2010","journal-title":"Laryngoscope"},{"key":"key20200713185149_b12-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1750-9378-6-3","article-title":"Human papillomavirus detection in moroccan patients with nasopharyngeal carcinoma","volume":"6","author":"Laantri","year":"2011","journal-title":"Infect Agent Cancer"},{"key":"key20200713185149_b13-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0304-3835(94)03667-8","article-title":"Detection of Epstein-Barr virus and human papillomavirus in nasopharyngeal carcinoma by the polymerase chain reaction technique","volume":"89","author":"Giannoudis","year":"1995","journal-title":"Cancer Lett"},{"key":"key20200713185149_b14-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"4892","DOI":"10.1002\/cncr.27395","article-title":"Multimodal treatment, including interferon beta, of nasopharyngeal carcinoma in children and young adults: Preliminary results from the prospective, multicenter study NPC-2003-GPOH\/DCOG","volume":"118","author":"Buehrlen","year":"2012","journal-title":"Cancer"},{"key":"key20200713185149_b15-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1055\/s-0041-111180","article-title":"Diagnosis and treatment of nasopharyngeal carcinoma in children and adolescents - Recommendations of the GPOH-NPC Study Group","volume":"228","author":"Kontny","year":"2016","journal-title":"Klin Padiatr"},{"key":"key20200713185149_b16-ijo-53-04-1721","article-title":"Hematoxylin and eosin staining of tissue and cell sections","volume":"2008","author":"Fischer","year":"2008","journal-title":"CSH Protoc"},{"key":"key20200713185149_b17-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1093\/annonc\/mdu450","article-title":"The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: Recommendations by an International TILs Working Group 2014","volume":"26","author":"Salgado","year":"2015","journal-title":"Ann Oncol"},{"key":"key20200713185149_b18-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1021\/np501007n","article-title":"Pharmacogenomic characterization of cytotoxic compounds from Salvia officinalis in cancer cells","volume":"78","author":"Kadioglu","year":"2015","journal-title":"J Nat Prod"},{"key":"key20200713185149_b19-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1080\/10503300802621180","article-title":"Creative consensus on interpretations of qualitative data: The Ward method","volume":"19","author":"Schielke","year":"2009","journal-title":"Psychother Res"},{"key":"key20200713185149_b20-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/sj.leu.2400669","article-title":"Apoptosis and resistance to daunorubicin in human leukemic cells","volume":"11","author":"Efferth","year":"1997","journal-title":"Leukemia"},{"key":"key20200713185149_b21-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1038\/73439","article-title":"A gene expression database for the molecular pharmacology of cancer","volume":"24","author":"Scherf","year":"2000","journal-title":"Nat Genet"},{"key":"key20200713185149_b22-ijo-53-04-1721","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/01.sla.0000150157.83537.53","article-title":"DNA array-based gene profiling: From surgical specimen to the molecular portrait of cancer","volume":"241","author":"Mocellin","year":"2005","journal-title":"Ann Surg"},{"key":"key20200713185149_b23-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"14863","DOI":"10.1073\/pnas.95.25.14863","article-title":"Cluster analysis and display of genome-wide expression patterns","volume":"95","author":"Eisen","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713185149_b24-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/35021093","article-title":"Molecular portraits of human breast tumours","volume":"406","author":"Perou","year":"2000","journal-title":"Nature"},{"key":"key20200713185149_b25-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/73432","article-title":"Systematic variation in gene expression patterns in human cancer cell lines","volume":"24","author":"Ross","year":"2000","journal-title":"Nat Genet"},{"key":"key20200713185149_b26-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.jprot.2014.06.025","article-title":"Identification of candidate biomarkers for the early detection of nasopharyngeal carcinoma by quantitative proteomic analysis","volume":"109","author":"Yang","year":"2014","journal-title":"J Proteomics"},{"key":"key20200713185149_b27-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1002\/cncr.25376","article-title":"Prognostic factors and long-term outcomes of childhood nasopharyngeal carcinoma","volume":"117","author":"Cheuk","year":"2011","journal-title":"Cancer"},{"key":"key20200713185149_b28-ijo-53-04-1721","first-page":"1843","article-title":"Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients","volume":"8","author":"Volm","year":"2002","journal-title":"Clin Cancer Res"},{"key":"key20200713185149_b29-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/sj.bjc.6600463","article-title":"Protein expression profiles indicative for drug resistance of non-small cell lung cancer","volume":"87","author":"Volm","year":"2002","journal-title":"Br J Cancer"},{"key":"key20200713185149_b30-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1023\/A:1016361924216","article-title":"Protein expression profile of primary human squamous cell lung carcinomas indicative of the incidence of metastases","volume":"19","author":"Volm","year":"2002","journal-title":"Clin Exp Metastasis"},{"key":"key20200713185149_b31-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"11139","DOI":"10.1128\/JVI.76.21.11139-11142.2002","article-title":"Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus","volume":"76","author":"Trempat","year":"2002","journal-title":"J Virol"},{"key":"key20200713185149_b32-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"7935","DOI":"10.1158\/0008-5472.CAN-09-0828","article-title":"EBV-induced human CD8+ NKT cells suppress tumorigenesis by EBV-associated malignancies","volume":"69","author":"Yuling","year":"2009","journal-title":"Cancer Res"},{"key":"key20200713185149_b33-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1111\/j.1349-7006.2006.00252.x","article-title":"Complementary activation of peripheral natural killer cell immunity in nasopharyngeal carcinoma","volume":"97","author":"Zheng","year":"2006","journal-title":"Cancer Sci"},{"key":"key20200713185149_b34-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.1200\/JCO.2010.30.5037","article-title":"Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer","volume":"29","author":"Mahmoud","year":"2011","journal-title":"J Clin Oncol"},{"key":"key20200713185149_b35-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1643","DOI":"10.4049\/jimmunol.180.3.1643","article-title":"EBV latent membrane proteins (LMPs) 1 and 2 as immunotherapeutic targets: LMP-specific CD4+ cytotoxic T cell recognition of EBV-transformed B cell lines","volume":"180","author":"Haigh","year":"2008","journal-title":"J Immunol"},{"key":"key20200713185149_b36-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1007\/s00432-015-1969-3","article-title":"Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma","volume":"141","author":"Stoker","year":"2015","journal-title":"J Cancer Res Clin Oncol"},{"key":"key20200713185149_b37-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1128\/JVI.78.2.768-778.2004","article-title":"Dual stimulation of Epstein-Barr Virus (EBV)-specific CD4+- and CD8+-T-cell responses by a chimeric antigen construct: Potential therapeutic vaccine for EBV-positive nasopharyngeal carcinoma","volume":"78","author":"Taylor","year":"2004","journal-title":"J Virol"},{"key":"key20200713185149_b38-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1093\/annonc\/mdh027","article-title":"Adoptive transfer of allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T cells with in vitro antitumor activity boosts LMP2-specific immune response in a patient with EBV-related nasopharyngeal carcinoma","volume":"15","author":"Comoli","year":"2004","journal-title":"Ann Oncol"},{"key":"key20200713185149_b39-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.bbabio.2010.10.008","article-title":"Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism","volume":"1807","author":"Chevrollier","year":"2011","journal-title":"Biochim Biophys Acta"},{"key":"key20200713185149_b40-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1593\/tlo.09250","article-title":"Targeting p53 for novel anticancer therapy","volume":"3","author":"Wang","year":"2010","journal-title":"Transl Oncol"},{"key":"key20200713185149_b41-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/35042675","article-title":"Surfing the p53 network","volume":"408","author":"Vogelstein","year":"2000","journal-title":"Nature"},{"key":"key20200713185149_b42-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"2973","DOI":"10.1101\/gad.12.19.2973","article-title":"The complexity of p53 modulation: Emerging patterns from divergent signals","volume":"12","author":"Giaccia","year":"1998","journal-title":"Genes Dev"},{"key":"key20200713185149_b43-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/0092-8674(90)90409-8","article-title":"The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53","volume":"63","author":"Scheffner","year":"1990","journal-title":"Cell"},{"key":"key20200713185149_b44-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1099\/0022-1317-67-9-1909","article-title":"The expression of human papillomavirus type 18 E6 protein in bacteria and the production of anti-E6 antibodies","volume":"67","author":"Matlashewski","year":"1986","journal-title":"J Gen Virol"},{"key":"key20200713185149_b45-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"319","DOI":"10.4143\/crt.2005.37.6.319","article-title":"The role of HPV E6 and E7 oncoproteins in HPV-associated cervical carcinogenesis","volume":"37","author":"Yim","year":"2005","journal-title":"Cancer Res Treat"},{"key":"key20200713185149_b46-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"28.6.1","DOI":"10.1002\/0471142727.mb2806s111","article-title":"Assaying cell cycle status using flow cytometry","volume":"111","author":"Kim","year":"2015","journal-title":"Curr Protoc Mol Biol"},{"key":"key20200713185149_b47-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"7212","DOI":"10.1200\/JCO.2005.07.501","article-title":"Proliferation marker Ki-67 in early breast cancer","volume":"23","author":"Urruticoechea","year":"2005","journal-title":"J Clin Oncol"},{"key":"key20200713185149_b48-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1097\/IGC.0b013e31823c36b8","article-title":"CD105\/Ki67 coexpression correlates with tumor progression and poor prognosis in epithelial ovarian cancer","volume":"22","author":"Liu","year":"2012","journal-title":"Int J Gynecol Cancer"},{"key":"key20200713185149_b49-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1002\/(SICI)1097-0347(199810)20:7<640::AID-HED11>3.0.CO;2-K","article-title":"Expression of bcl-2-, p53, and Ki-67 and outcome of patients with primary nasopharyngeal carcinomas following DNA-damaging treatment","volume":"20","author":"Masuda","year":"1998","journal-title":"Head Neck"},{"key":"key20200713185149_b50-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1016\/j.bbagrm.2014.10.005","article-title":"The role of eIF3 and its individual subunits in cancer","volume":"1849","author":"Hershey","year":"2015","journal-title":"Biochim Biophys Acta"},{"key":"key20200713185149_b51-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1016\/j.yexcr.2009.03.009","article-title":"Role of eIF3a in regulating cell cycle progression","volume":"315","author":"Dong","year":"2009","journal-title":"Exp Cell Res"},{"key":"key20200713185149_b52-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"4600","DOI":"10.1158\/1078-0432.CCR-10-2591","article-title":"Effect of eIF3a on response of lung cancer patients to platinum-based chemotherapy by regulating DNA repair","volume":"17","author":"Yin","year":"2011","journal-title":"Clin Cancer Res"},{"key":"key20200713185149_b53-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1023\/A:1005960822365","article-title":"Role of nitric oxide in tumor progression: Lessons from experimental tumors","volume":"17","author":"Lala","year":"1998","journal-title":"Cancer Metastasis Rev"},{"key":"key20200713185149_b54-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.niox.2008.05.003","article-title":"The reemergence of nitric oxide and cancer","volume":"19","author":"Wink","year":"2008","journal-title":"Nitric Oxide"},{"key":"key20200713185149_b55-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1073\/pnas.87.4.1620","article-title":"Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide","volume":"87","author":"Beckman","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713185149_b56-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/S0360-3016(03)00122-6","article-title":"Inducible nitric oxide synthase and bcl-2 expression in naso-pharyngeal cancer: Correlation with outcome of patients after radiotherapy","volume":"56","author":"Jayasurya","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key20200713185149_b57-ijo-53-04-1721","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1038\/sj.bjp.0703944","article-title":"Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival","volume":"132","author":"Kane","year":"2001","journal-title":"Br J Pharmacol"}],"container-title":["International Journal of Oncology"],"original-title":[],"deposited":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T05:45:33Z","timestamp":1604641533000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijo.2018.4491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,19]]},"references-count":57,"URL":"https:\/\/doi.org\/10.3892\/ijo.2018.4491","relation":{},"ISSN":["1019-6439","1791-2423"],"issn-type":[{"value":"1019-6439","type":"print"},{"value":"1791-2423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,19]]}}}