{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T17:14:56Z","timestamp":1773076496956,"version":"3.50.1"},"reference-count":27,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Oncol"],"DOI":"10.3892\/ijo.2019.4823","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T06:51:25Z","timestamp":1559803885000},"source":"Crossref","is-referenced-by-count":16,"title":["Cystathionine\u2011\u03b3\u2011lyase promotes the metastasis of breast cancer via the VEGF signaling pathway"],"prefix":"10.3892","author":[{"given":"Lupeng","family":"Wang","sequence":"first","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haimei","family":"Shi","sequence":"additional","affiliation":[{"name":"Anesthesiology Department, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofang","family":"Duan","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianxiao","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Henan University, Kaifeng, Henan 475004, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,6,6]]},"reference":[{"key":"key20200713185934_b1-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"7335","DOI":"10.1158\/1078-0432.CCR-04-0183","article-title":"Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: A novel model for tumor progression","volume":"10","author":"Davidson","year":"2004","journal-title":"Clin Cancer Res"},{"key":"key20200713185934_b2-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1093\/carcin\/bgh146","article-title":"Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-\u03b1 dependent up-regulation of matrix metalloproteases","volume":"25","author":"Hagemann","year":"2004","journal-title":"Carcinogenesis"},{"key":"key20200713185934_b3-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1677\/erc.1.01270","article-title":"Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: Implications for tumour-stroma interactions","volume":"13","author":"Hiscox","year":"2006","journal-title":"Endocr Relat Cancer"},{"key":"key20200713185934_b4-ijo-55-02-0473","first-page":"p400","volume-title":"Molecular Biology of Cancer","author":"Pecorino","year":"2005"},{"key":"key20200713185934_b5-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21332","article-title":"Cancer statistics, 2016","volume":"66","author":"Siegel","year":"2016","journal-title":"CA Cancer J Clin"},{"key":"key20200713185934_b6-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"21972","DOI":"10.1073\/pnas.0908047106","article-title":"Hydrogen sulfide is an endogenous stimulator of angiogenesis","volume":"106","author":"Papapetropoulos","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713185934_b7-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1093\/biolre\/iox105","article-title":"Human trophoblast-derived hydrogen sulfide stimulates placental artery endothelial cell angiogenesis","volume":"97","author":"Chen","year":"2017","journal-title":"Biol Reprod"},{"key":"key20200713185934_b8-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1089\/ars.2009.2938","article-title":"Hydrogen sulfide: The third gasotransmitter in biology and medicine","volume":"12","author":"Wang","year":"2010","journal-title":"Antioxid Redox Signal"},{"key":"key20200713185934_b9-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/ars.2008.2282","article-title":"Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria","volume":"12","author":"Kimura","year":"2010","journal-title":"Antioxid Redox Signal"},{"key":"key20200713185934_b10-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1111\/jcmm.12114","article-title":"Hydrogen sulphide suppresses human atrial fibroblast proliferation and transformation to myofibro-blasts","volume":"17","author":"Sheng","year":"2013","journal-title":"J Cell Mol Med"},{"key":"key20200713185934_b11-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3109\/13813455.2013.803578","article-title":"An outlook on vascular hydrogen sulphide effects, signalling, and therapeutic potential","volume":"119","author":"Popov","year":"2013","journal-title":"Arch Physiol Biochem"},{"key":"key20200713185934_b12-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.phrs.2016.08.026","article-title":"Regulation and role of endogenously produced hydrogen sulfide in angiogenesis","volume":"113","author":"Katsouda","year":"2016","journal-title":"Pharmacol Res"},{"key":"key20200713185934_b13-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1111\/bph.14446","article-title":"Regulators of the transsulfu-ration pathway","volume":"176","author":"Sbodio","year":"2019","journal-title":"Br J Pharmacol"},{"key":"key20200713185934_b14-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1016\/j.cellsig.2012.02.003","article-title":"Sp1 is involved in regulation of cystathionine \u03b3-lyase gene expression and biological function by PI3K\/Akt pathway in human hepatocellular carcinoma cell lines","volume":"24","author":"Yin","year":"2012","journal-title":"Cell Signal"},{"key":"key20200713185934_b15-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1042\/CBI20090368","article-title":"Hydrogen sulfide induces human colon cancer cell proliferation: Role of Akt, ERK and p21","volume":"34","author":"Cai","year":"2010","journal-title":"Cell Biol Int"},{"key":"key20200713185934_b16-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"65677","DOI":"10.18632\/oncotarget.20057","article-title":"Cystathionine-\u03b3-lyase promotes process of breast cancer in association with STAT3 signaling pathway","volume":"8","author":"You","year":"2017","journal-title":"Oncotarget"},{"key":"key20200713185934_b17-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s13277-010-0047-3","article-title":"Quantitative analysis of BCL2 mRNA expression in nasopharyngeal carcinoma: An unfavorable and independent prognostic factor","volume":"31","author":"Fendri","year":"2010","journal-title":"Tumour Biol"},{"key":"key20200713185934_b18-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3390\/antiox6020029","article-title":"HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation","volume":"6","author":"Nitti","year":"2017","journal-title":"Antioxidants"},{"key":"key20200713185934_b19-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/1476-4598-7-23","article-title":"Lymphangiogenesis and lymph node metastasis in breast cancer","volume":"7","author":"Cunnick","year":"2008","journal-title":"Mol Cancer"},{"key":"key20200713185934_b20-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nrc1098","article-title":"The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited","volume":"3","author":"Fidler","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"key20200713185934_b21-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/j.cell.2016.11.037","article-title":"Emerging biological principles of metastasis","volume":"168","author":"Lambert","year":"2017","journal-title":"Cell"},{"key":"key20200713185934_b22-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1023\/A:1022542519586","article-title":"Breast cancer metastasis suppressor 1: Update","volume":"20","author":"Meehan","year":"2003","journal-title":"Clin Exp Metastasis"},{"key":"key20200713185934_b23-ijo-55-02-0473","first-page":"1417","article-title":"Expression of breast cancer metastasis suppressor-1, BRMS-1, in human breast cancer and the biological impact of BRMS-1 on the migration of breast cancer cells","volume":"34","author":"Zhang","year":"2014","journal-title":"Anticancer Res"},{"key":"key20200713185934_b24-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"130","DOI":"10.2174\/1874091X01812010130","article-title":"Co-administration of fish oil with signal transduction inhibitors has anti-migration effects in breast cancer cell lines, in vitro","volume":"12","author":"Davison","year":"2018","journal-title":"Open Biochem J"},{"key":"key20200713185934_b25-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"46652","DOI":"10.18632\/oncotarget.16938","article-title":"Triple negative breast cancer: The kiss of death","volume":"8","author":"Jitariu","year":"2017","journal-title":"Oncotarget"},{"key":"key20200713185934_b26-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1080\/15384047.2017.1394542","article-title":"Main components of pomegranate, ellagic acid and luteolin, inhibit metastasis of ovarian cancer by down-regulating MMP2 and MMP9","volume":"18","author":"Liu","year":"2017","journal-title":"Cancer Biol Ther"},{"issue":"Suppl 3","key":"key20200713185934_b27-ijo-55-02-0473","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1159\/000088478","article-title":"VEGF as a key mediator of angiogenesis in cancer","volume":"69","author":"Carmeliet","year":"2005","journal-title":"Oncology"}],"container-title":["International Journal of Oncology"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T19:05:19Z","timestamp":1594667119000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ijo.2019.4823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,6]]},"references-count":27,"URL":"https:\/\/doi.org\/10.3892\/ijo.2019.4823","relation":{},"ISSN":["1019-6439","1791-2423"],"issn-type":[{"value":"1019-6439","type":"print"},{"value":"1791-2423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,6]]}}}