{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:11:21Z","timestamp":1782738681036,"version":"3.54.5"},"reference-count":25,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["mol clin onc"],"DOI":"10.3892\/mco.2019.1962","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T13:39:27Z","timestamp":1575639567000},"source":"Crossref","is-referenced-by-count":1,"title":["Mixed adenoneuroendocrine carcinoma of the liver: A rare case report"],"prefix":"10.3892","author":[{"given":"Jiao\u2011Jiao","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2011Ping","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2011Li","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu\u2011Yang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian\u2011Ping","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing\u2011Ming","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2019,12,6]]},"reference":[{"issue":"10","key":"key20200713202706_b1-mco-0-0-1962","doi-asserted-by":"publisher","DOI":"10.4103\/2156-7514.107995","article-title":"Mixed adenoneuroendocrine carcinoma of cecum: A rare entity","volume":"3","author":"Jain","year":"2013","journal-title":"J Clin Imaging Sci"},{"key":"key20200713202706_b2-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ijscr.2018.09.031","article-title":"Cystic mixed adenoneuroendocrine carcinoma of the pancreas: A case report","volume":"52","author":"Shimada","year":"2018","journal-title":"Int J Surg Case Rep"},{"key":"key20200713202706_b3-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1159\/000437293","article-title":"Mixed adenoneuroendocrine carcinoma of the stomach","volume":"9","author":"Kwok","year":"2015","journal-title":"Case Rep Gastroenterol"},{"key":"key20200713202706_b4-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"562","DOI":"10.9738\/INTSURG-D-14-00074.1","article-title":"A case of mixed adenoneuroendocrine carcinoma of the stomach with focal intestinal metaplasia and hypergastrinemia","volume":"100","author":"Yamauchi","year":"2015","journal-title":"Int Surg"},{"key":"key20200713202706_b5-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1111\/j.1600-0463.2006.apm_407.x","article-title":"Pancreatic endocrine tumor with partial acinar cell differentiation","volume":"114","author":"Minakawa","year":"2006","journal-title":"APMIS"},{"issue":"9542687","key":"key20200713202706_b6-mco-0-0-1962","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9542687","article-title":"Mixed adenoneuroendocrine carcinoma is a rare but important tumour found in the oesophagus","volume":"2016","author":"Kadhim","year":"2016","journal-title":"Case Rep Gastrointest Med"},{"key":"key20200713202706_b7-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"e70","DOI":"10.5301\/tj.5000254","article-title":"Amphicrine carcinoma of the ampullary region","volume":"101","author":"Ginori","year":"2015","journal-title":"Tumori"},{"key":"key20200713202706_b8-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.3748\/wjg.v21.i4.1329","article-title":"Mixed adenoneuroendocrine carcinoma of gastrointestinal tract: Report of two cases","volume":"21","author":"Gurzu","year":"2015","journal-title":"World J Gastroenterol"},{"key":"key20200713202706_b9-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"3161","DOI":"10.3748\/wjg.v19.i20.3161","article-title":"Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma","volume":"19","author":"Onishi","year":"2013","journal-title":"World J Gastroenterol"},{"key":"key20200713202706_b10-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1677\/ERC-10-0152","article-title":"Gastroenteropancreatic neuroendocrine tumours: The current incidence and staging based on the WHO and European neuroendocrine tumour society classification: An analysis based on prospectively collected parameters","volume":"17","author":"Niederle","year":"2010","journal-title":"Endocr Relat Cancer"},{"issue":"e9189","key":"key20200713202706_b11-mco-0-0-1962","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009189","article-title":"Correlation of metastasis characteristics with prognosis in gastric mixed adenoneuroendocrine carcinoma: Two case reports","volume":"96","author":"Tang","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"key20200713202706_b12-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3390\/cancers4010011","article-title":"Mixed Adenoneuroendocrine carcinomas (MANECs) of the gastrointestinal tract: An update","volume":"4","author":"La Rosa","year":"2012","journal-title":"Cancers (Basel)"},{"key":"key20200713202706_b13-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s00428-006-0306-2","article-title":"The grey zone between pure (neuro)endocrine and non-(neuro)endocrine tumours: A comment on concepts and classification of mixed exocrine-endocrine neoplasms","volume":"449","author":"Volante","year":"2006","journal-title":"Virchows Arch"},{"key":"key20200713202706_b14-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1097\/01.lab.0000079006.91414.be","article-title":"Microallelotyping defines the monoclonal or the polyclonal origin of mixed and collision endocrine-exocrine tumors of the gut","volume":"83","author":"Furlan","year":"2003","journal-title":"Lab Invest"},{"key":"key20200713202706_b15-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1111\/j.1440-1827.2011.02709.x","article-title":"Mixed adenoneuroendocrine carcinoma (MANEC) of the gallbladder: A possible stem cell tumor?","volume":"61","author":"Paniz","year":"2011","journal-title":"Pathol Int"},{"key":"key20200713202706_b16-mco-0-0-1962","first-page":"5517","article-title":"Mixed adenoneuroendocrine carcinoma of the colon: Molecular pathogenesis and treatment","volume":"34","author":"Vanacker","year":"2014","journal-title":"Anticancer Res"},{"key":"key20200713202706_b17-mco-0-0-1962","first-page":"6333","article-title":"Neuroendocrine liver metastasis in gastric mixed adenoneuroendocrine carcinoma with trilineage cell differentiation: A case report","volume":"7","author":"Zhang","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"key20200713202706_b18-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1111\/j.1600-0463.2005.apm_190.x","article-title":"Composite glandular-endocrine cell carcinomas of the stomach: Clinicopathologic and methylation study","volume":"113","author":"Lee","year":"2005","journal-title":"APMIS"},{"key":"key20200713202706_b19-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"63","DOI":"10.5230\/jgc.2014.14.1.63","article-title":"Mixed adenoneuroendocrine gastric carcinoma: A case report and review of the literature","volume":"14","author":"Levi","year":"2014","journal-title":"J Gastric Cancer"},{"key":"key20200713202706_b20-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1159\/000369071","article-title":"Mixed adenoneuroendocrine carcinomas of the gastrointestinal tract: Targeted next-generation sequencing suggests a monoclonal origin of the two components","volume":"100","author":"Scardoni","year":"2014","journal-title":"Neuroendocrinology"},{"key":"key20200713202706_b21-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"195","DOI":"10.5230\/jgc.2011.11.4.195","article-title":"Clinicopathologic significance of gastric adenocarcinoma with neuroendocrine features","volume":"11","author":"Kim","year":"2011","journal-title":"J Gastric Cancer"},{"key":"key20200713202706_b22-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"280","DOI":"10.5946\/ce.2013.46.3.280","article-title":"A gastric composite tumor with an adenocarcinoma and a neuroendocrine carcinoma: A case report","volume":"46","author":"Lee","year":"2013","journal-title":"Clin Endosc"},{"key":"key20200713202706_b23-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1097\/PAS.0b013e3182093657","article-title":"Colorectal glandular-neuroendocrine mixed tumor: Pathologic spectrum and clinical implications","volume":"35","author":"Li","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"key20200713202706_b24-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1159\/000335595","article-title":"ENETS Consensus Guidelines for the management of patients with gastroduodenal neoplasms","volume":"95","author":"Delle","year":"2012","journal-title":"Neuroendocrinology"},{"key":"key20200713202706_b25-mco-0-0-1962","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1016\/j.dld.2016.08.112","article-title":"The multidisciplinary management of gastro-oesophageal junction tumours: European society of digestive oncology (ESDO): Expert discussion and report from the 16th ESMO world congress on gastrointestinal cancer, barcelona","volume":"48","author":"Van Laethem","year":"2016","journal-title":"Dig Liver Dis"}],"container-title":["Molecular and Clinical Oncology"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T19:27:15Z","timestamp":1594668435000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mco.2019.1962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,6]]},"references-count":25,"URL":"https:\/\/doi.org\/10.3892\/mco.2019.1962","relation":{},"ISSN":["2049-9450","2049-9469"],"issn-type":[{"value":"2049-9450","type":"print"},{"value":"2049-9469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,6]]}}}