{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:42:16Z","timestamp":1789868536166,"version":"4.0.1"},"reference-count":44,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Clin Oncol"],"DOI":"10.3892\/mco.2024.2793","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T10:25:14Z","timestamp":1729247114000},"source":"Crossref","is-referenced-by-count":3,"title":["Incidence of myelosuppression in AML is higher compared with that in ALL"],"prefix":"10.3892","volume":"21","author":[{"given":"Wanling","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Xiamen Medical College, Xiamen, Fujian 361023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongtao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Xiamen Medical College, Xiamen, Fujian 361023, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiasheng","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Hematology, Zhongshan Hospital of Xiamen University, Xiamen, Fujian 361004, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2024,10,18]]},"reference":[{"key":"key20241101101612_b1-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.emc.2014.04.004","article-title":"Acute leukemia","volume":"32","author":"Rose-Inman","year":"2014","journal-title":"Emerg Med Clin North Am"},{"issue":"e577","key":"key20241101101612_b2-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2017.53","article-title":"Acute lymphoblastic leukemia: A comprehensive review and 2017 update","volume":"7","author":"Terwilliger","year":"2017","journal-title":"Blood Cancer J"},{"issue":"19","key":"key20241101101612_b3-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-023-01417-5","article-title":"Treatment outcomes for newly diagnosed, treatment-na\u00efve TP53-mutated acute myeloid leukemia: A systematic review and meta-analysis","volume":"16","author":"Daver","year":"2023","journal-title":"J Hematol Oncol"},{"key":"key20241101101612_b4-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1016\/S0140-6736(19)33018-1","article-title":"Acute lymphoblastic leukaemia","volume":"395","author":"Malard","year":"2020","journal-title":"Lancet"},{"key":"key20241101101612_b5-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21551","article-title":"Cancer statistics, 2019","volume":"69","author":"Siegel","year":"2019","journal-title":"CA Cancer J Clin"},{"key":"key20241101101612_b6-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.blre.2019.04.005","article-title":"Epidemiology of acute myeloid leukemia: Recent progress and enduring challenges","volume":"36","author":"Shallis","year":"2019","journal-title":"Blood Rev"},{"key":"key20241101101612_b7-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1182\/blood-2008-06-164863","article-title":"Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century","volume":"113","author":"Pulte","year":"2009","journal-title":"Blood"},{"issue":"e85554","key":"key20241101101612_b8-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085554","article-title":"Survival of adults with acute lymphoblastic leukemia in Germany and the United States","volume":"9","author":"Pulte","year":"2014","journal-title":"PLoS One"},{"key":"key20241101101612_b9-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1200\/JCO.2011.37.8018","article-title":"Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: A report from the children's oncology group","volume":"30","author":"Hunger","year":"2012","journal-title":"J Clin Oncol"},{"key":"key20241101101612_b10-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"199","DOI":"10.2174\/1871529X18666180515130136","article-title":"Acute myeloid leukemia: Diagnosis and management based on current molecular genetics approach","volume":"18","author":"Suguna","year":"2018","journal-title":"Cardiovasc Hematol Disord Drug Targets"},{"key":"key20241101101612_b11-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1111\/j.1365-2141.1976.tb03563.x","article-title":"Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group","volume":"33","author":"Bennett","year":"1976","journal-title":"Br J Haematol"},{"key":"key20241101101612_b12-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"2391","DOI":"10.1182\/blood-2016-03-643544","article-title":"The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia","volume":"127","author":"Arber","year":"2016","journal-title":"Blood"},{"issue":"150950","key":"key20241101101612_b13-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2019.150950","article-title":"Acute leukemia: Diagnosis and treatment","volume":"35","author":"Blackburn","year":"2019","journal-title":"Semin Oncol Nurs"},{"key":"key20241101101612_b14-MCO-21-6-02793","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1055\/s-0043-1764369","article-title":"Role of morphology in the diagnosis of acute leukemias: Systematic review","volume":"44","author":"Sekar","year":"2023","journal-title":"Indian J Med Paediatr Oncol"},{"key":"key20241101101612_b15-MCO-21-6-02793","first-page":"107","article-title":"Morphology of leukaemias","volume":"79","author":"Ladines-Castro","year":"2016","journal-title":"Rev M\u00e9d Hosp Gen M\u00e9x"},{"key":"key20241101101612_b16-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"42","DOI":"10.4274\/tjh.galenos.2019.2019.0241","article-title":"WHO 2016 definition of chronic myeloid leukemia and tyrosine kinase inhibitors","volume":"37","author":"Haznedaro\u011flu","year":"2020","journal-title":"Turk J Haematol"},{"issue":"e0011622","key":"key20241101101612_b17-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011622","article-title":"Characteristics and risk factors for readmission in HIV-infected patients with Talaromyces marneffei infection","volume":"17","author":"Shi","year":"2023","journal-title":"PLoS Negl Trop Dis"},{"issue":"890745","key":"key20241101101612_b18-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.890745","article-title":"Novel diagnostic and prognostic tools for lung cancer cachexia: Based on nutritional and inflammatory status","volume":"12","author":"Liu","year":"2022","journal-title":"Front Oncol"},{"issue":"103126","key":"key20241101101612_b19-MCO-21-6-02793","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2020.103126","article-title":"Development and validation of a prognostic model for adult patients with acute myeloid leukaemia","volume":"62","author":"Ma","year":"2020","journal-title":"EBioMedicine"},{"key":"key20241101101612_b20-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"2246","DOI":"10.1002\/(sici)1097-0142(19991201)86:11<2246::aid-cncr11>3.0.co;2-i","article-title":"A phase I-II trial of escalating doses of mitoxantrone with fixed doses of cytarabine plus fludarabine as salvage therapy for patients with acute leukemia and the blastic phase of chronic myelogenous leukemia","volume":"86","author":"Koller","year":"1999","journal-title":"Cancer"},{"key":"key20241101101612_b21-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1056\/NEJMoa1300874","article-title":"Retinoic acid and arsenic trioxide for acute promyelocytic leukemia","volume":"369","author":"Lo-Coco","year":"2013","journal-title":"N Engl J Med"},{"key":"key20241101101612_b22-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1935","DOI":"10.1182\/blood-2012-08-449918","article-title":"Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the international consortium on APL","volume":"121","author":"Rego","year":"2013","journal-title":"Blood"},{"key":"key20241101101612_b23-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"309","DOI":"10.4103\/0019-509X.176731","article-title":"Clinico-hematological profile and outcome of acute promyelocytic leukemia patients at a tertiary care center in North India","volume":"52","author":"Dayama","year":"2015","journal-title":"Indian J Cancer"},{"key":"key20241101101612_b24-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"v69","DOI":"10.1093\/annonc\/mdw025","article-title":"Acute lymphoblastic leukaemia in adult patients: ESMO clinical practice guidelines for diagnosis, treatment and follow-up","volume":"27 (Suppl 5)","author":"Hoelzer","year":"2016","journal-title":"Ann Oncol"},{"key":"key20241101101612_b25-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1016\/S0140-6736(08)60457-2","article-title":"Acute lymphoblastic leukaemia","volume":"371","author":"Pui","year":"2008","journal-title":"Lancet"},{"key":"key20241101101612_b26-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/s0272-2712(03)00071-4","article-title":"Acute leukemia","volume":"22","author":"Schumacher","year":"2002","journal-title":"Clin Lab Med"},{"key":"key20241101101612_b27-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.disamonth.2012.01.011","article-title":"Adult acute leukemia","volume":"58","author":"Cornell","year":"2012","journal-title":"Dis Mon"},{"key":"key20241101101612_b28-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0147-0272(97)80006-2","article-title":"Adult acute leukemia","volume":"21","author":"Cripe","year":"1997","journal-title":"Curr Probl Cancer"},{"key":"key20241101101612_b29-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"78","DOI":"10.12968\/bjon.2012.21.2.76","article-title":"Acute leukaemia: Making sense of a complex blood cancer","volume":"21","author":"Meenaghan","year":"2012","journal-title":"Br J Nurs"},{"key":"key20241101101612_b30-MCO-21-6-02793","doi-asserted-by":"crossref","first-page":"740","DOI":"10.7326\/0003-4819-87-6-740","article-title":"Classification of acute leukemia","volume":"87","author":"Gralnick","year":"1977","journal-title":"Ann Intern Med"},{"key":"key20241101101612_b31-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"9623","DOI":"10.1073\/pnas.92.21.9623","article-title":"Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis","volume":"92","author":"Weiss","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20241101101612_b32-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"7976","DOI":"10.1073\/pnas.94.15.7976","article-title":"An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice","volume":"94","author":"McDevitt","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20241101101612_b33-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/ajh.21332","article-title":"Clinical significance of Gata-1, Gata-2, EKLF, asnd c-MPL expression in acute myeloid leukemia","volume":"84","author":"Ayala","year":"2009","journal-title":"Am J Hematol"},{"key":"key20241101101612_b34-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1038\/375318a0","article-title":"Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF","volume":"375","author":"Perkins","year":"1995","journal-title":"Nature"},{"key":"key20241101101612_b35-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1046\/j.1365-2141.1999.01304.x","article-title":"Definition of a standard-risk group in children with AML","volume":"104","author":"Creutzig","year":"1999","journal-title":"Br J Haematol"},{"key":"key20241101101612_b36-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1586\/14737140.3.5.695","article-title":"Epidemiology and clinical burden of acute myeloid leukemia","volume":"3","author":"Redaelli","year":"2003","journal-title":"Expert Rev Anticancer Ther"},{"key":"key20241101101612_b37-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1016\/j.hoc.2011.09.017","article-title":"Prognostic factors in adult acute leukemia","volume":"25","author":"Ganzel","year":"2011","journal-title":"Hematol Oncol Clin North Am"},{"key":"key20241101101612_b38-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.clml.2011.03.035","article-title":"Prognostic significance of leukopenia at the time of diagnosis in acute myeloid leukemia","volume":"11","author":"Arellano","year":"2011","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"key20241101101612_b39-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1002\/cncr.33458","article-title":"De novo acute myeloid leukemia: A population-based study of outcome in the United States based on the surveillance, epidemiology, and end results (SEER) database, 1980 to 2017","volume":"127","author":"Sasaki","year":"2021","journal-title":"Cancer"},{"key":"key20241101101612_b40-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"3342","DOI":"10.1073\/pnas.0813280106","article-title":"Long-term efficacy and safety of all-trans retinoic acid\/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia","volume":"106","author":"Hu","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20241101101612_b41-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1200\/JCO.2010.30.1382","article-title":"Modern therapy of acute lymphoblastic leukemia","volume":"29","author":"Bassan","year":"2011","journal-title":"J Clin Oncol"},{"key":"key20241101101612_b42-MCO-21-6-02793","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1182\/blood.V60.3.677.677","article-title":"Adolescent and adult acute lymphoblastic leukemia: Prognostic features and outcome of therapy. A study of 293 patients","volume":"60","author":"Baccarani","year":"1982","journal-title":"Blood"},{"key":"key20241101101612_b43-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1093\/tropej\/46.6.338","article-title":"Age, sex, haemoglobin level, and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol","volume":"46","author":"Ng","year":"2000","journal-title":"J Trop Pediatr"},{"key":"key20241101101612_b44-MCO-21-6-02793","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s12098-007-0040-z","article-title":"Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia","volume":"74","author":"Settin","year":"2007","journal-title":"Indian J Pediatr"}],"container-title":["Molecular and Clinical Oncology"],"original-title":[],"deposited":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T08:16:22Z","timestamp":1730448982000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mco.2024.2793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,18]]},"references-count":44,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,10,18]]}},"URL":"https:\/\/doi.org\/10.3892\/mco.2024.2793","relation":{},"ISSN":["2049-9450","2049-9469"],"issn-type":[{"value":"2049-9450","type":"print"},{"value":"2049-9469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,18]]},"article-number":"95"}}