{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:20:18Z","timestamp":1791084018689,"version":"4.1.0"},"reference-count":75,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Clin Oncol"],"DOI":"10.3892\/mco.2025.2831","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:57:56Z","timestamp":1741154276000},"page":"1-10","source":"Crossref","is-referenced-by-count":5,"title":["Endocrine paraneoplastic syndromes in lung cancer: A call for clinical vigilance (Review)"],"prefix":"10.3892","volume":"22","author":[{"given":"Maria-Evangelia","family":"Koloutsou","sequence":"first","affiliation":[{"name":"First Department of Propaedeutic Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Soura","sequence":"additional","affiliation":[{"name":"First Department of Propaedeutic Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Andreikos","sequence":"additional","affiliation":[{"name":"School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demetrios","family":"Spandidos","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Yavropoulou","sequence":"additional","affiliation":[{"name":"Endocrinology Unit, First Department of Propaedeutic and Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Georgakopoulou","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"key20250317083702_b1-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"key20250317083702_b2-MCO-22-4-02831","author":"Ferlay"},{"key":"key20250317083702_b3-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"6253","DOI":"10.21037\/jtd.2020.03.88","article-title":"Paraneoplastic syndromes in small cell lung cancer","volume":"12","author":"Soomro","year":"2020","journal-title":"J Thorac Dis"},{"key":"key20250317083702_b4-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1053\/j.semdp.2019.01.002","article-title":"Paraneoplastic syndromes: Definitions, classification, pathophysiology and principles of treatment","volume":"36","author":"Henry","year":"2019","journal-title":"Semin Diagn Pathol"},{"key":"key20250317083702_b5-MCO-22-4-02831","author":"Thapa"},{"issue":"359","key":"key20250317083702_b6-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.04.86","article-title":"Paraneoplastic syndromes in lung cancer and their management","volume":"7","author":"Anwar","year":"2019","journal-title":"Ann Transl Med"},{"key":"key20250317083702_b7-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"R173","DOI":"10.1530\/ERC-17-0036","article-title":"Paraneoplastic endocrine syndromes","volume":"24","author":"Dimitriadis","year":"2017","journal-title":"Endocr Relat Cancer"},{"issue":"101621","key":"key20250317083702_b8-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2022.101621","article-title":"Endocrine abnormality in paraneoplastic syndrome","volume":"36","author":"Onyema","year":"2022","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"key20250317083702_b9-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/0002-9343(57)90224-3","article-title":"A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone","volume":"23","author":"Schwartz","year":"1975","journal-title":"Am J Med"},{"key":"key20250317083702_b10-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1056\/NEJM196309122691102","article-title":"Carcinoma of the lung with inappropriate antidiuresis. Demonstration of antidiuretic-hormone-like activity in tumor extract","volume":"269","author":"Amatruda","year":"1963","journal-title":"N Engl J Med"},{"key":"key20250317083702_b11-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1001\/jama.2022.11176","article-title":"Diagnosis and management of hyponatremia: A review","volume":"328","author":"Adrogu\u00e9","year":"2022","journal-title":"JAMA"},{"key":"key20250317083702_b12-MCO-22-4-02831","first-page":"4104","article-title":"The productions of atrial natriuretic peptide and arginine vasopressin in small cell lung cancer with brain metastases and their associations with hyponatremia","volume":"21","author":"Sun","year":"2017","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"e43390","key":"key20250317083702_b13-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.43390","article-title":"A conspectus of euvolemic hyponatremia, its various etiologies, and treatment modalities: A comprehensive review of the literature","volume":"15","author":"Ghosal","year":"2023","journal-title":"Cureus"},{"key":"key20250317083702_b14-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/j.1365-2796.1995.tb00907.x","article-title":"Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in malignant disease","volume":"238","author":"S\u00f8rensen","year":"1995","journal-title":"J Intern Med"},{"key":"key20250317083702_b15-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1210\/endrev\/bnad010","article-title":"Syndrome of inappropriate antidiuresis: From pathophysiology to management","volume":"44","author":"Warren","year":"2023","journal-title":"Endocr Rev"},{"key":"key20250317083702_b16-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"503","DOI":"10.7861\/clinmed.2023-0227","article-title":"Treatment of hypercalcaemia of malignancy in adults","volume":"23","author":"Mc Donald","year":"2023","journal-title":"Clin Med (Lond)"},{"key":"key20250317083702_b17-MCO-22-4-02831","first-page":"496","article-title":"Hypercalcemia of malignancy","volume":"9","author":"Feldenzer","year":"2018","journal-title":"J Adv Pract Oncol"},{"issue":"1553","key":"key20250317083702_b18-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12101553","article-title":"What lies behind paraneoplastic hypercalcemia secondary to well-differentiated neuroendocrine neoplasms? A systematic review of the literature","volume":"12","author":"Giannetta","year":"2022","journal-title":"J Pers Med"},{"key":"key20250317083702_b19-MCO-22-4-02831","author":"Goltzman"},{"issue":"1039490","key":"key20250317083702_b20-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1039490","article-title":"Cancer-related hypercalcemia and potential treatments","volume":"14","author":"Almuradova","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"key20250317083702_b21-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"R13","DOI":"10.1530\/EC-20-0487","article-title":"Treatment of malignancy-associated hypercalcemia with cinacalcet: A paradigm shift","volume":"10","author":"O'Callaghan","year":"2021","journal-title":"Endocr Connect"},{"key":"key20250317083702_b22-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3892\/ol.2016.4572","article-title":"Paraneoplastic Cushing's syndrome associated with bronchopulmonary carcinoid tumor in youth: A case report and review of the literature","volume":"12","author":"Li","year":"2016","journal-title":"Oncol Lett"},{"key":"key20250317083702_b23-MCO-22-4-02831","author":"Galli"},{"issue":"e13120","key":"key20250317083702_b24-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1111\/jne.13120","article-title":"Medical management of Cushing's disease: When and how?","volume":"34","author":"Castinetti","year":"2022","journal-title":"J Neuroendocrinol"},{"issue":"5440","key":"key20250317083702_b25-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15225440","article-title":"Lung carcinoids: A comprehensive review for clinicians","volume":"15","author":"Granberg","year":"2023","journal-title":"Cancers (Basel)"},{"key":"key20250317083702_b26-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"R145","DOI":"10.1530\/ERC-18-0495","article-title":"Management of carcinoid syndrome: A systematic review and meta-analysis","volume":"26","author":"Hofland","year":"2019","journal-title":"Endocr Relat Cancer"},{"key":"key20250317083702_b27-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"2140","DOI":"10.1007\/s10620-019-05525-6","article-title":"Generalized cytokine increase in the setting of a multisystem clinical disorder and carcinoid syndrome associated with a novel NLRP12 variant","volume":"64","author":"Jacob","year":"2019","journal-title":"Dig Dis Sci"},{"issue":"662","key":"key20250317083702_b28-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3332\/ecancer.2016.662","article-title":"Complications from carcinoid syndrome: review of the current evidence","volume":"10","author":"Mota","year":"2016","journal-title":"Ecancermedicalscience"},{"key":"key20250317083702_b29-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1093\/annonc\/mdv041","article-title":"Pulmonary neuroendocrine (carcinoid) tumors: European neuroendocrine tumor society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids","volume":"26","author":"Caplin","year":"2015","journal-title":"Ann Oncol"},{"issue":"e1972","key":"key20250317083702_b30-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1972","article-title":"Non-islet cell tumor hypoglycemia: A rare cause of hypoglycemia in pulmonary sarcomatoid cancer","volume":"9","author":"Legare","year":"2017","journal-title":"Cureus"},{"issue":"60","key":"key20250317083702_b31-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-020-0529-2","article-title":"A case of insulin-like growth factor 2-producing gastrointestinal stromal tumor with severe hypoglycemia","volume":"20","author":"Yamasaki","year":"2020","journal-title":"BMC Endocr Disord"},{"key":"key20250317083702_b32-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1210\/jc.2013-3382","article-title":"Management of non-islet-cell tumor hypoglycemia: A clinical review","volume":"99","author":"Bodnar","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"e00471","key":"key20250317083702_b33-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1002\/edm2.471","article-title":"A systematic review of literature on Insulin-like growth factor-2-mediated hypoglycaemia in non-islet cell tumours","volume":"7","author":"Ata","year":"2024","journal-title":"Endocrinol Diabetes Metab"},{"key":"key20250317083702_b34-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1210\/jc.2006-2573","article-title":"Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung","volume":"92","author":"Nauck","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"key20250317083702_b35-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"232","DOI":"10.4183\/aeb.2022.232","article-title":"Igf-2 induced hypoglycemia associated with lung sarcoma","volume":"18","author":"Gherbon","year":"2022","journal-title":"Acta Endocrinol (Buchar)"},{"key":"key20250317083702_b36-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1210\/clinem\/dgac596","article-title":"Management of individuals with diabetes at high risk for hypoglycemia: An endocrine society clinical practice guideline","volume":"108","author":"McCall","year":"2023","journal-title":"J Clin Endocrinol Metab"},{"key":"key20250317083702_b37-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3892\/or.2020.7892","article-title":"IGFBP2 in cancer: Pathological role and clinical significance (Review)","volume":"45","author":"Wei","year":"2021","journal-title":"Oncol Rep"},{"key":"key20250317083702_b38-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.eprac.2022.11.010","article-title":"Clinical presentation and diagnostic approach to hypoglycemia in adults without diabetes mellitus","volume":"29","author":"Palani","year":"2023","journal-title":"Endocr Pract"},{"key":"key20250317083702_b39-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1002\/phar.2534","article-title":"Glucagon: Its evolving role in the management of hypoglycemia","volume":"41","author":"Isaacs","year":"2021","journal-title":"Pharmacotherapy"},{"issue":"140097","key":"key20250317083702_b40-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-14-0097","article-title":"Prolonged life-threatening hypoglycaemia following dose escalation of octreotide LAR in a patient with malignant polysecreting pancreatic neuroendocrine tumour","volume":"2015","author":"Abell","year":"2015","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"key20250317083702_b41-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"R147","DOI":"10.1530\/EJE-13-1012","article-title":"Management of endocrine disease: A clinical update on tumor-induced hypoglycemia","volume":"170","author":"Iglesias","year":"2014","journal-title":"Eur J Endocrinol"},{"key":"key20250317083702_b42-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1055\/a-2170-1691","article-title":"Recurrent Non-islet cell tumor hypoglycemia secondary to hepatocellular carcinoma: Case report and literature review","volume":"62","author":"He","year":"2024","journal-title":"Z Gastroenterol"},{"issue":"100305","key":"key20250317083702_b43-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1016\/j.metop.2024.100305","article-title":"Paraneoplastic hypoglycemia: An overview for optimal clinical guidance","volume":"23","author":"Karamanolis","year":"2024","journal-title":"Metabol Open"},{"key":"key20250317083702_b44-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s12020-012-9790-0","article-title":"Ectopic acromegaly due to growth hormone releasing hormone","volume":"43","author":"Ghazi","year":"2013","journal-title":"Endocrine"},{"issue":"e397","key":"key20250317083702_b45-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.37029\/jcas.v7i1.397","article-title":"Ectopic acromegaly secondary to bronchial tumour: A case report of rare occurrence","volume":"7","author":"Sohail","year":"2021","journal-title":"J Cancer Allied Spec"},{"key":"key20250317083702_b46-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"3933","DOI":"10.1210\/jc.2014-2700","article-title":"Acromegaly: An endocrine society clinical practice guideline","volume":"99","author":"Katznelson","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"bvae194","key":"key20250317083702_b47-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1210\/jendso\/bvae194","article-title":"Recognition and management of ectopic ACTH secreting tumors","volume":"9","author":"Elenius","year":"2025","journal-title":"J Endocr Soc"},{"issue":"867965","key":"key20250317083702_b48-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.867965","article-title":"Acromegaly caused by ectopic growth hormone releasing hormone secretion: A review","volume":"13","author":"Zendran","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3282","key":"key20250317083702_b49-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15133282","article-title":"Pro-gastrin-releasing peptide as a biomarker in lung neuroendocrine neoplasm","volume":"15","author":"Rosiek","year":"2023","journal-title":"Cancers (Basel)"},{"key":"key20250317083702_b50-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"5890","DOI":"10.3748\/wjg.v27.i35.5890","article-title":"Gastrinoma and Zollinger Ellison syndrome: A roadmap for the management between new and old therapies","volume":"27","author":"Rossi","year":"2021","journal-title":"World J Gastroenterol"},{"key":"key20250317083702_b51-MCO-22-4-02831","author":"Metz"},{"key":"key20250317083702_b52-MCO-22-4-02831","author":"Cho"},{"issue":"179","key":"key20250317083702_b53-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-016-0718-z","article-title":"Effective and safe proton pump inhibitor therapy in acid-related diseases-A position paper addressing benefits and potential harms of acid suppression","volume":"14","author":"Scarpignato","year":"2016","journal-title":"BMC Med"},{"key":"key20250317083702_b54-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s11154-018-9443-6","article-title":"Supportive therapy in gastroenteropancreatic neuroendocrine tumors: Often forgotten but important","volume":"19","author":"Jin","year":"2018","journal-title":"Rev Endocr Metab Disord"},{"key":"key20250317083702_b55-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"4673","DOI":"10.3748\/wjg.v25.i32.4673","article-title":"Surgical management of Zollinger-Ellison syndrome: Classical considerations and current controversies","volume":"25","author":"Shao","year":"2019","journal-title":"World J Gastroenterol"},{"key":"key20250317083702_b56-MCO-22-4-02831","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.47191\/ijmscrs\/v2-i12-27","article-title":"Clinical and surgical management of Zollinger-Ellison syndrome: A literature review","volume":"2","author":"Verdugo","year":"2022","journal-title":"Int J Med Sci Clin Res Stud"},{"key":"key20250317083702_b57-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s12020-017-1420-4","article-title":"The Zollinger-Ellison syndrome: Is there a role for somatostatin analogues in the treatment of the gastrinoma?","volume":"60","author":"Guarnotta","year":"2018","journal-title":"Endocrine"},{"issue":"1377","key":"key20250317083702_b58-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15051377","article-title":"Successful lifetime\/long-term medical treatment of acid hypersecretion in Zollinger-Ellison syndrome (ZES): Myth or fact? Insights from an analysis of results of NIH long-term prospective studies of ZES","volume":"15","author":"Ito","year":"2023","journal-title":"Cancers (Basel)"},{"key":"key20250317083702_b59-MCO-22-4-02831","doi-asserted-by":"crossref","first-page":"523","DOI":"10.12775\/JEHS.2022.12.08.055","article-title":"Zollinger-Ellison syndrome-review","volume":"12","author":"Metelski","year":"2022","journal-title":"J Educ Health Sport"},{"key":"key20250317083702_b60-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/S0140-6736(15)00817-X","article-title":"Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): A randomised, placebo-controlled, phase 3 study","volume":"387","author":"Yao","year":"2016","journal-title":"Lancet"},{"key":"key20250317083702_b61-MCO-22-4-02831","author":"Swerdloff"},{"key":"key20250317083702_b62-MCO-22-4-02831","doi-asserted-by":"crossref","first-page":"421","DOI":"10.4103\/jdmimsu.jdmimsu_411_21","article-title":"Paraneoplastic syndrome presenting with unilateral gynecomastia: Ultrasonography, mammography, and strain elastography evaluation","volume":"17","author":"Gowda","year":"2022","journal-title":"J Datta Meghe Inst Med Sci Univ"},{"key":"key20250317083702_b63-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"150","DOI":"10.4103\/2230-8210.129104","article-title":"Gynecomastia: Clinical evaluation and management","volume":"18","author":"Cuhaci","year":"2014","journal-title":"Indian J Endocrinol Metab"},{"key":"key20250317083702_b64-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1007\/s00404-020-05927-2","article-title":"Lung neoplasm mimicking as ectopic pregnancy due to paraneoplastic secretion of human chorionic gonadotropin: A case report and literature review","volume":"303","author":"Peng","year":"2021","journal-title":"Arch Gynecol Obstet"},{"key":"key20250317083702_b65-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"7256","DOI":"10.3892\/ol.2018.9525","article-title":"Focal positivity of immunohistochemical markers for pulmonary squamous cell carcinoma in primary pulmonary choriocarcinoma: A histopathological study","volume":"16","author":"Matsukuma","year":"2018","journal-title":"Oncol Lett"},{"key":"key20250317083702_b66-MCO-22-4-02831","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jons.2016.07.003","article-title":"Cannonball lung metastases as a presenting feature of ectopic hCG expression","volume":"2","author":"Yang","year":"2016","journal-title":"J Oncol Sci"},{"issue":"e54758","key":"key20250317083702_b67-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.54758","article-title":"A lung cancer patient presenting with gynecomastia: An uncommon paraneoplastic syndrome","volume":"16","author":"Sanjan","year":"2024","journal-title":"Cureus"},{"key":"key20250317083702_b68-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"108","DOI":"10.4103\/jomfp.JOMFP_271_18","article-title":"Estimation of expression of beta-human chorionic gonadotropin levels through progression of disease from normal to epithelial dysplasia to malignancy","volume":"23","author":"Singh","year":"2019","journal-title":"J Oral Maxillofac Pathol"},{"key":"key20250317083702_b69-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.rmcr.2018.12.001","article-title":"Galactorrhea, mastodynia and gynecomastia as the first manifestation of lung adenocarcinoma. A case report","volume":"26","author":"Lazopoulos","year":"2018","journal-title":"Respir Med Case Rep"},{"key":"key20250317083702_b70-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"E773","DOI":"10.1093\/neuros\/nyy386","article-title":"Prolactin-secreting lung adenocarcinoma metastatic to the pituitary mimicking a prolactinoma: A case report","volume":"85","author":"Yao","year":"2019","journal-title":"Neurosurgery"},{"key":"key20250317083702_b71-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/ars.2013.5581","article-title":"Receptor-independent ectopic activity of prolactin predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies","volume":"23","author":"Le Bescont","year":"2015","journal-title":"Antioxid Redox Signal"},{"issue":"e20021","key":"key20250317083702_b72-MCO-22-4-02831","article-title":"Ectopic prolactin production by lung cancer cells as an indicator of aggressive nature of tumors","volume":"37 (15 Suppl)","author":"Legostaev","year":"2019","journal-title":"J Clin Oncol"},{"key":"key20250317083702_b73-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1097\/JCMA.0000000000000584","article-title":"Treatment of hyperprolactinemia: A single-institute experience","volume":"84","author":"Chen","year":"2021","journal-title":"J Chin Med Assoc"},{"key":"key20250317083702_b74-MCO-22-4-02831","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1210\/jc.2010-1692","article-title":"Diagnosis and treatment of hyperprolactinemia: An endocrine society clinical practice guideline","volume":"96","author":"Melmed","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"issue":"5553187","key":"key20250317083702_b75-MCO-22-4-02831","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5553187","article-title":"Prolactin-secreting leiomyoma causing hyperprolactinaemia unresponsive to dopamine agonist therapy and resolution following myomectomy","volume":"2021","author":"Barry","year":"2021","journal-title":"Case Rep Endocrinol"}],"container-title":["Molecular and Clinical Oncology"],"original-title":[],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T06:37:10Z","timestamp":1742193430000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mco.2025.2831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,5]]},"references-count":75,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,3,5]]}},"URL":"https:\/\/doi.org\/10.3892\/mco.2025.2831","relation":{},"ISSN":["2049-9450","2049-9469"],"issn-type":[{"value":"2049-9450","type":"print"},{"value":"2049-9469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,5]]}}}