{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T09:06:24Z","timestamp":1780995984845,"version":"3.54.1"},"reference-count":13,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Clin Oncol"],"DOI":"10.3892\/mco.2026.2953","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:10:26Z","timestamp":1777896626000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Urinary metabolomic signatures associated with early adverse events during volumetric modulated arc therapy for prostate cancer: A secondary analysis of a public dataset"],"prefix":"10.3892","volume":"25","author":[{"given":"Mai","family":"Fukushi","sequence":"first","affiliation":[{"name":"Department of Radiation Science, Hirosaki University Graduate School of Health Sciences, Hirosaki, Aomori 036\u20118564, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yota","family":"Tatara","sequence":"additional","affiliation":[{"name":"Department of Stress Response Science, Biomedical Research Center, Graduate School of Medicine, Hirosaki University, Hirosaki, Aomori 036\u20118562, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Obara","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hirosaki University Hospital, Hirosaki, Aomori 036\u20118563, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Monzen","sequence":"additional","affiliation":[{"name":"Department of Radiation Science, Hirosaki University Graduate School of Health Sciences, Hirosaki, Aomori 036\u20118564, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"key20260609114110_b1-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","article-title":"GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"key20260609114110_b2-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1111\/iju.15545","article-title":"Japanese clinical practice guidelines for prostate cancer 2023","volume":"31","author":"Kohjimoto","year":"2024","journal-title":"Int J of Urol"},{"key":"key20260609114110_b3-MCO-25-1-02953"},{"key":"key20260609114110_b4-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3857\/roj.2014.32.3.103","article-title":"Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials","volume":"32","author":"Kim","year":"2014","journal-title":"Radiat Oncol J"},{"key":"key20260609114110_b5-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1667\/RR2437.1","article-title":"Radiation metabolomics. 4. UPLC-ESI-QTOFMS-Based metabolomics for urinary biomarker discovery in gamma-irradiated rats","volume":"175","author":"Johnson","year":"2011","journal-title":"Radiat Res"},{"key":"key20260609114110_b6-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1021\/pr500913n","article-title":"Metabolomic and lipidomic analysis of serum from mice exposed to an internal emitter, cesium-137, using a shotgun LC-MS(E) approach","volume":"14","author":"Goudarzi","year":"2015","journal-title":"J Proteome Res"},{"issue":"2270","key":"key20260609114110_b7-MCO-25-1-02953","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13132270","article-title":"Urinary metabolomic analysis of prostate cancer by UPLC-FTMS and UPLC-Ion Trap MSn","volume":"13","author":"Chen","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"62","key":"key20260609114110_b8-MCO-25-1-02953","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2024.2760","article-title":"Exploring predictive molecules of acute adverse events in response to volumetric-modulated arc therapy for prostate cancer using urinary metabolites","volume":"21","author":"Obara","year":"2024","journal-title":"Mol Clin Oncol"},{"key":"key20260609114110_b9-MCO-25-1-02953"},{"key":"key20260609114110_b10-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"W514","DOI":"10.1093\/nar\/gky510","article-title":"OmicsNet: A web-based tool for creation and visual analysis of biological networks in 3D space","volume":"46","author":"Zhou","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"key20260609114110_b11-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.cmet.2006.03.005","article-title":"Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome","volume":"3","author":"Lass","year":"2006","journal-title":"Cell Metab"},{"key":"key20260609114110_b12-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1194\/jlr.r200013-jlr200","article-title":"Carboxyl ester lipase: Structure-function relationship and physiological role in lipoprotein metabolism and atherosclerosis","volume":"43","author":"Hui","year":"2002","journal-title":"J Lipid Res"},{"key":"key20260609114110_b13-MCO-25-1-02953","doi-asserted-by":"publisher","first-page":"E205","DOI":"10.1152\/ajpendo.00053.2015","article-title":"Fat in flames: Influence of cytokines and pattern recognition receptors on adipocyte lipolysis","volume":"309","author":"Grant","year":"2015","journal-title":"Am J Physiol Endocrinol Metab"}],"container-title":["Molecular and Clinical Oncology"],"original-title":[],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T08:41:17Z","timestamp":1780994477000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mco.2026.2953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,5,4]]}},"URL":"https:\/\/doi.org\/10.3892\/mco.2026.2953","relation":{},"ISSN":["2049-9450","2049-9469"],"issn-type":[{"value":"2049-9450","type":"print"},{"value":"2049-9469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}