{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:29:00Z","timestamp":1787056140853,"version":"build-2736575974"},"reference-count":53,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Clin Oncol"],"DOI":"10.3892\/mco.2026.2967","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T08:43:01Z","timestamp":1785228181000},"page":"1-11","source":"Crossref","is-referenced-by-count":0,"title":["Short\u2011term and long\u2011term outcomes of non\u2011tracheal intubation anesthesia in thoracoscopic lobectomy for lung cancer: A systematic review and meta\u2011analysis"],"prefix":"10.3892","volume":"25","author":[{"given":"Lizhi","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Shenzhen Bao'an District People's Hospital, Shenzhen, Guangdong 518100, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangshun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shenzhen Bao'an District People's Hospital, Shenzhen, Guangdong 518100, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"key20260818144050_b1-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"key20260818144050_b2-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ccm.2019.10.001","article-title":"Lung cancer 2020: Epidemiology, etiology, and prevention","volume":"41","author":"Bade","year":"2020","journal-title":"Clin Chest Med"},{"key":"key20260818144050_b3-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.cnc.2019.05.002","article-title":"Surgical treatment of lung cancer","volume":"31","author":"Hoy","year":"2019","journal-title":"Crit Care Nurs Clin North Am"},{"key":"key20260818144050_b4-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1016\/S1470-2045(16)00173-X","article-title":"Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: A randomised controlled trial","volume":"17","author":"Bendixen","year":"2016","journal-title":"Lancet Oncol"},{"issue":"44","key":"key20260818144050_b5-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-021-01270-4","article-title":"Procedural times in early non-intubated VATS program - a propensity score analysis","volume":"21","author":"Metelmann","year":"2021","journal-title":"BMC Anesthesiol"},{"key":"key20260818144050_b6-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1001\/jamasurg.2016.4952","article-title":"Enhanced recovery after surgery: A review","volume":"152","author":"Ljungqvist","year":"2017","journal-title":"JAMA Surg"},{"key":"key20260818144050_b7-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1093\/ejcts\/ezv136","article-title":"Non-intubated video-assisted thoracoscopic lung resections: The future of thoracic surgery?","volume":"49","author":"Gonzalez-Rivas","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"issue":"937633","key":"key20260818144050_b8-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.937633","article-title":"Non-intubated thoracic surgery: Standpoints and perspectives","volume":"9","author":"Anile","year":"2022","journal-title":"Front Surg"},{"key":"key20260818144050_b9-MCO-25-3-02967","author":"Wells"},{"key":"key20260818144050_b10-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: Is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"issue":"39","key":"key20260818144050_b11-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.1186\/2049-3258-72-39","article-title":"Metaprop: A stata command to perform meta-analysis of binomial data","volume":"72","author":"Nyaga","year":"2014","journal-title":"Arch Public Health"},{"key":"key20260818144050_b12-MCO-25-3-02967","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/1536867X0800800102","article-title":"Metan: Fixed- and random-effects meta-analysis","volume":"8","author":"Harris","year":"2008","journal-title":"Stata J"},{"key":"key20260818144050_b13-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"key20260818144050_b14-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1111\/j.0006-341x.2000.00455.x","article-title":"Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"key20260818144050_b15-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"3875","DOI":"10.21037\/tlcr-21-629","article-title":"Perioperative and long-term outcomes of spontaneous ventilation video-assisted thoracoscopic surgery for non-small cell lung cancer","volume":"10","author":"Zheng","year":"2021","journal-title":"Transl Lung Cancer Res"},{"key":"key20260818144050_b16-MCO-25-3-02967","author":"Zhao"},{"key":"key20260818144050_b17-MCO-25-3-02967","first-page":"455","article-title":"Comparison of laryngeal mask anesthesia and intubation anesthesia under spontaneous ventilation in uniportal video-assisted thoracoscopic surgery","volume":"33","author":"Zhang","year":"2017","journal-title":"J Pract Med"},{"key":"key20260818144050_b18-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.asjsur.2023.09.038","article-title":"Non-intubated versus intubated video-assisted thoracoscopic lobectomy for lung cancer patients","volume":"47","author":"Yu","year":"2024","journal-title":"Asian J Surg"},{"key":"key20260818144050_b19-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.athoracsur.2012.10.082","article-title":"Feasibility and safety of nonintubated thoracoscopic lobectomy for geriatric lung cancer patients","volume":"95","author":"Wu","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"key20260818144050_b20-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.1016\/j.jfma.2021.04.018","article-title":"Long-term outcomes after nonintubated versus intubated thoracoscopic lobectomy for clinical stage I non-small cell lung cancer: A propensity-matched analysis","volume":"120","author":"Wang","year":"2021","journal-title":"J Formos Med Assoc"},{"key":"key20260818144050_b21-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"2863","DOI":"10.1007\/s13304-024-01935-y","article-title":"Comparison of postoperative pulmonary complications and intraoperative safety in thoracoscopic surgery under non-intubated versus intubated anesthesia: A randomized, controlled, double-blind non-inferiority trial","volume":"76","author":"Wang","year":"2024","journal-title":"Updates Surg"},{"key":"key20260818144050_b22-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.21037\/jtd-23-591","article-title":"Perioperative morbidity and 3-year survival in non-intubated thoracoscopic surgery: A propensity matched analysis","volume":"16","author":"Udelsman","year":"2024","journal-title":"J Thorac Dis"},{"key":"key20260818144050_b23-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"e329","DOI":"10.1111\/ajco.13726","article-title":"Clinical application of preserving spontaneous breathing non-intubation anesthesia in thoracoscopic surgery for lung cancer under ERAS concept","volume":"18","author":"Qi","year":"2022","journal-title":"Asia Pac J Clin Oncol"},{"issue":"154","key":"key20260818144050_b24-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-022-01667-9","article-title":"Perioperative outcomes of non-intubated versus intubated video-assisted thoracoscopic surgery in different thoracic procedures: A propensity score-matched analysis","volume":"22","author":"Pathonsamit","year":"2022","journal-title":"BMC Anesthesiol"},{"issue":"1175437","key":"key20260818144050_b25-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1175437","article-title":"Clinical application of intubation-free anesthesia in radical resection of lung cancer","volume":"10","author":"Liu","year":"2023","journal-title":"Front Med (Lausanne)"},{"key":"key20260818144050_b26-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1093\/ejcts\/ezw160","article-title":"The impact of non-intubated versus intubated anaesthesia on early outcomes of video-assisted thoracoscopic anatomical resection in non-small-cell lung cancer: A propensity score matching analysis","volume":"50","author":"Liu","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"key":"key20260818144050_b27-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"8081","DOI":"10.12659\/MSM.910605","article-title":"A propensity score-matched analysis for non-intubated thoracic surgery","volume":"24","author":"Lan","year":"2018","journal-title":"Med Sci Monit"},{"key":"key20260818144050_b28-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1093\/icvts\/ivaa265","article-title":"Comparison of early postoperative cytokine changes in patients undergoing intubated and non-intubated thoracic surgery: A randomized controlled trial","volume":"32","author":"Jeon","year":"2021","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"key20260818144050_b29-MCO-25-3-02967","first-page":"1019","article-title":"Uniportal video-assisted thoracoscopic surgery for non-small cell lung cancer under non-intubated anesthesia with spontaneous respiration","volume":"32","author":"Fang","year":"2018","journal-title":"J Chin Pract Diagn Ther"},{"issue":"880007","key":"key20260818144050_b30-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.880007","article-title":"Non-intubated versus intubated video-assisted thoracic surgery in patients aged 75 years and older: A propensity matching study","volume":"9","author":"Chen","year":"2022","journal-title":"Front Surg"},{"key":"key20260818144050_b31-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1097\/SLA.0b013e31822ed19b","article-title":"Nonintubated thoracoscopic lobectomy for lung cancer","volume":"254","author":"Chen","year":"2011","journal-title":"Ann Surg"},{"key":"key20260818144050_b32-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"4236","DOI":"10.21037\/jtd.2018.06.163","article-title":"Comparison of non-intubated versus intubated video-assisted thoracoscopic lobectomy for lung cancer","volume":"10","author":"AlGhamdi","year":"2018","journal-title":"J Thorac Dis"},{"key":"key20260818144050_b33-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"31","DOI":"10.2217\/fon-2016-0340","article-title":"Techniques of video-assisted thoracoscopic surgery lobectomy and critical review of published data","volume":"12","author":"Andrews","year":"2016","journal-title":"Future Oncol"},{"key":"key20260818144050_b34-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.athoracsur.2020.05.144","article-title":"Survival after thoracoscopic surgery or open lobectomy: Systematic review and meta-analysis","volume":"111","author":"Hernandez-Vaquero","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"key20260818144050_b35-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.jfma.2019.08.009","article-title":"A survey of one-lung ventilation device in lung resection surgeries in Taiwan-A population-based nationwide cohort study","volume":"119","author":"Wang","year":"2020","journal-title":"J Formos Med Assoc"},{"key":"key20260818144050_b36-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"464","DOI":"10.21037\/jtd-22-114","article-title":"Comparison of two preoperative positioning techniques and unpositioning methods in non-intubated video-assisted thoracoscopic surgery","volume":"14","author":"Yu","year":"2022","journal-title":"J Thorac Dis"},{"issue":"853643","key":"key20260818144050_b37-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.853643","article-title":"Non-intubated thoracic surgery: Wedge resections for peripheral pulmonary nodules","volume":"9","author":"Ambrogi","year":"2022","journal-title":"Front Surg"},{"issue":"872496","key":"key20260818144050_b38-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.872496","article-title":"Electromagnetic navigation bronchoscopy integrated non-intubated uniportal VATS in localization and resection of pulmonary nodules","volume":"9","author":"Wang","year":"2022","journal-title":"Front Surg"},{"key":"key20260818144050_b39-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.3978\/j.issn.2072-1439.2014.11.39","article-title":"Nonintubated anesthesia for thoracic surgery","volume":"6","author":"Wang","year":"2014","journal-title":"J Thorac Dis"},{"key":"key20260818144050_b40-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3978\/j.issn.2072-1439.2014.01.03","article-title":"Anesthetic consideration for nonintubated VATS","volume":"6","author":"Yang","year":"2014","journal-title":"J Thorac Dis"},{"issue":"1783","key":"key20260818144050_b41-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-6434","article-title":"Clinical evaluation of the rapid recovery of patients who underwent video-assisted thoracoscopic lung surgery under non-intubated anesthesia","volume":"9","author":"Cai","year":"2021","journal-title":"Ann Transl Med"},{"key":"key20260818144050_b42-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1016\/j.athoracsur.2007.01.049","article-title":"Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancer","volume":"83","author":"Whitson","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"key20260818144050_b43-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"1644","DOI":"10.1016\/s0003-4975(00)01909-3","article-title":"Better pulmonary function and prognosis with video-assisted thoracic surgery than with thoracotomy","volume":"70","author":"Kaseda","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"key20260818144050_b44-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1177\/1553350614531662","article-title":"Nonintubated video-assisted thoracoscopic surgery under epidural anesthesia compared with conventional anesthetic option: A randomized control study","volume":"22","author":"Liu","year":"2015","journal-title":"Surg Innov"},{"key":"key20260818144050_b45-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"4101","DOI":"10.21037\/jtd.2019.10.04","article-title":"Expert consensus on tubeless video-assisted thoracoscopic surgery (Guangzhou)","volume":"11","author":"He","year":"2019","journal-title":"J Thorac Dis"},{"issue":"518","key":"key20260818144050_b46-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.10.08","article-title":"Expert consensus on spontaneous ventilation video-assisted thoracoscopic surgery in primary spontaneous pneumothorax (Guangzhou)","volume":"7","author":"He","year":"2019","journal-title":"Ann Transl Med"},{"issue":"272","key":"key20260818144050_b47-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-025-03154-3","article-title":"Comparison of non-intubated and intubated video-assisted thoracoscopic surgery for perioperative complications-a systematic review and meta-analysis","volume":"25","author":"Zhang","year":"2025","journal-title":"BMC Anesthesiol"},{"key":"key20260818144050_b48-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"3556","DOI":"10.21037\/jtd.2019.07.48","article-title":"Non-intubated video-assisted thoracoscopic surgery vs. intubated video-assisted thoracoscopic surgery for thoracic disease: A systematic review and meta-analysis of 1,684 cases","volume":"11","author":"Zhang","year":"2019","journal-title":"J Thorac Dis"},{"issue":"e0224737","key":"key20260818144050_b49-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0224737","article-title":"Non-intubated anesthesia in patients undergoing video-assisted thoracoscopic surgery: A systematic review and meta-analysis","volume":"14","author":"Yu","year":"2019","journal-title":"PLoS One"},{"issue":"1661466","key":"key20260818144050_b50-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2025.1661466","article-title":"Non-intubated vs. intubated video-assisted thoracoscopic surgery for the treatment of thoracic diseases: A systematic review and meta-analysis of propensity score-matched cohorts","volume":"12","author":"Luo","year":"2025","journal-title":"Front Surg"},{"issue":"6731","key":"key20260818144050_b51-MCO-25-3-02967","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14196731","article-title":"Is less more? A meta-analysis of non-intubated versus intubated VATS for anatomic resections in non-small cell lung cancer","volume":"14","author":"Magouliotis","year":"2025","journal-title":"J Clin Med"},{"key":"key20260818144050_b52-MCO-25-3-02967","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1093\/icvts\/ivaa141","article-title":"Non-intubated thoracoscopic lobectomies for lung cancer: An exploratory systematic review and meta-analysis","volume":"31","author":"Prisciandaro","year":"2020","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"key20260818144050_b53-MCO-25-3-02967","first-page":"1181","article-title":"Short-term efficacy of non-tracheal intubation anesthesia in thoracoscopic lobectomy for lung cancer: A systematic review and meta-analysis","volume":"32","author":"Yang","year":"2025","journal-title":"Chin J Clin Thorac Cardiovasc Surg"}],"container-title":["Molecular and Clinical Oncology"],"original-title":[],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T11:41:01Z","timestamp":1787053261000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mco.2026.2967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":53,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,7,28]]}},"URL":"https:\/\/doi.org\/10.3892\/mco.2026.2967","relation":{},"ISSN":["2049-9450","2049-9469"],"issn-type":[{"value":"2049-9450","type":"print"},{"value":"2049-9469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,28]]}}}