{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:31:20Z","timestamp":1792290680635,"version":"4.4.0"},"reference-count":34,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Int"],"DOI":"10.3892\/mi.2025.217","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T07:26:11Z","timestamp":1738740371000},"source":"Crossref","is-referenced-by-count":1,"title":["Depth of submucosal invasion vs. Haggitt level as prognostic predictors of pedunculated\u2011type early\u2011stage colorectal cancer removed by endoscopic resection\u00a0"],"prefix":"10.3892","volume":"5","author":[{"given":"Yasuo","family":"Imai","sequence":"first","affiliation":[{"name":"Department of Diagnostic Pathology, Ota Memorial Hospital, SUBARU Health Insurance Society, Ota, Gunma 373\u20118585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Otake","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ota Memorial Hospital, SUBARU Health Insurance Society, Ota, Gunma 373\u20118585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohide","family":"Tamachi","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Shioya Hospital, International University of Health and Welfare, Yaita, Tochigi 329\u20112145, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tateki","family":"Yamane","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Shioya Hospital, International University of Health and Welfare, Yaita, Tochigi 329\u20112145, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Shimao","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Shioya Hospital, International University of Health and Welfare, Yaita, Tochigi 329\u20112145, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Sugihara","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Ota Memorial Hospital, SUBARU Health Insurance Society, Ota, Gunma 373\u20118585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Ichinose","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Shioya Hospital, International University of Health and Welfare, Yaita, Tochigi 329\u20112145, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"key20250227091319_b1-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1136\/gut.25.5.437","article-title":"Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy","volume":"25","author":"Morson","year":"1984","journal-title":"Gut"},{"key":"key20250227091319_b2-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1007\/s005350170041","article-title":"Precancerous lesion of the colorectum","volume":"36","author":"Fujimori","year":"2001","journal-title":"J Gastroenterol"},{"key":"key20250227091319_b3-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1097\/00000478-198310000-00002","article-title":"Surgical pathology of endoscopically removed malignant polyps of the colon and rectum","volume":"7","author":"Cooper","year":"1983","journal-title":"Am J Surg Pathol"},{"key":"key20250227091319_b4-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"2044","DOI":"10.1002\/1097-0142(19921015)70:8<2044::aid-cncr2820700805>3.0.co;2-x","article-title":"The care of patients with colorectal polyps that contain invasive adenocarcinoma","volume":"70","author":"Kyzer","year":"1992","journal-title":"Cancer"},{"key":"key20250227091319_b5-MI-5-2-00217","first-page":"1035","article-title":"Early invasive colorectal carcinomas metastatic to the lymph node with attention to their nonpolypoid development","volume":"88","author":"Minamoto","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"key20250227091319_b6-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1007\/BF02349636","article-title":"Endoscopic treatment of submucosal invasive colorectal carcinoma with special reference to risk factors for lymph node metastasis","volume":"30","author":"Tanaka","year":"1995","journal-title":"J Gastroenterol"},{"key":"key20250227091319_b7-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"175","DOI":"10.23922\/jarc.2019-018","article-title":"Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma: The 3d English Edition [Secondary Publication]","volume":"3","year":"2019","journal-title":"J Anus Rectum Colon"},{"key":"key20250227091319_b8-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/s0016-5107(03)02159-x","article-title":"The Paris endoscopic classification of superficial neoplastic lesions: Esophagus, stomach, and colon: November 30 to December 1, 2002","volume":"58","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"key20250227091319_b9-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10147-019-01485-z","article-title":"Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer","volume":"25","author":"Hashiguchi","year":"2020","journal-title":"Int J Clin Oncol"},{"key":"key20250227091319_b10-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.bpg.2023.101848","article-title":"Surveillance after colorectal cancer resection","volume":"355","author":"Berman","year":"2000","journal-title":"Lancet"},{"key":"key20250227091319_b11-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1053\/j.gastro.2004.04.022","article-title":"Risk factors for an adverse outcome in early invasive colorectal carcinoma","volume":"127","author":"Ueno","year":"2004","journal-title":"Gastroenterology"},{"key":"key20250227091319_b12-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"783","DOI":"10.3892\/or.7.4.783","article-title":"Conditions of curability after endoscopic resection for colorectal carcinoma with submucosally massive invasion","volume":"7","author":"Tanaka","year":"2000","journal-title":"Oncol Rep"},{"key":"key20250227091319_b13-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/0016-5085(85)90333-6","article-title":"Prognostic factors in colorectal carcinomas arising in adenomas: Implications for lesions removed by endoscopic polypectomy","volume":"89","author":"Haggitt","year":"1985","journal-title":"Gastroenterology"},{"key":"key20250227091319_b14-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.gie.2013.04.163","article-title":"Role of endoscopy in the staging and management of colorectal cancer","volume":"78","author":"Fisher","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"key20250227091319_b15-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1055\/s-0034-1392882","article-title":"Endoscopic submucosal dissection: European society of gastrointestinal endoscopy (ESGE) guideline","volume":"7","author":"Pimentel-Nunes","year":"2015","journal-title":"Endoscopy"},{"key":"key20250227091319_b16-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1159\/000366036","article-title":"Risk assessment in early colorectal cancer: Histological and molecular markers","volume":"33","author":"Resch","year":"2015","journal-title":"Dig Dis"},{"key":"key20250227091319_b17-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1053\/j.gastro.2018.01.023","article-title":"Histologic factors associated with need for surgery in patients with pedunculated T1 colorectal carcinomas","volume":"154","author":"Backes","year":"2018","journal-title":"Gastroenterology"},{"issue":"2530","key":"key20250227091319_b18-MI-5-2-00217","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12092530","article-title":"pT1 colorectal cancer detected in a colorectal cancer mass screening program: Treatment and factors associated with residual and extraluminal disease","volume":"12","author":"Cubiella","year":"2020","journal-title":"Cancers (Basel)"},{"key":"key20250227091319_b19-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1159\/000526633","article-title":"Diagnostic and therapeutic management of early colorectal cancer","volume":"39","author":"Knoblauch","year":"2023","journal-title":"Visc Med"},{"key":"key20250227091319_b20-MI-5-2-00217","author":"Nagtegaal"},{"key":"key20250227091319_b21-MI-5-2-00217"},{"key":"key20250227091319_b22-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"13129","DOI":"10.3390\/ijms140713129","article-title":"Diagnosis of desmoplastic reaction by immunohistochemical analysis, in biopsy specimens of early colorectal carcinoma, is efficacious in estimating the depth of invasion","volume":"14","author":"Ohno","year":"2013","journal-title":"Int J Mol Sci"},{"key":"key20250227091319_b23-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1101\/gad.279737.116","article-title":"Carcinoma-associated fibroblasts: Orchestrating the composition of malignancy","volume":"30","author":"Gascard","year":"2016","journal-title":"Genes Dev"},{"key":"key20250227091319_b24-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1093\/jjco\/hyab040","article-title":"Histopathological atlas of desmoplastic reaction characterization in colorectal cancer","volume":"51","author":"Ueno","year":"2021","journal-title":"Jpn J Clin Oncol"},{"key":"key20250227091319_b25-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1007\/s00535-004-1339-4","article-title":"Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: A Japanese collaborative study","volume":"39","author":"Kitajima","year":"2004","journal-title":"J Gastroenterol"},{"key":"key20250227091319_b26-MI-5-2-00217"},{"key":"key20250227091319_b27-MI-5-2-00217","first-page":"2255","article-title":"Management of early pedunculated colorectal cancer","volume":"64","author":"Fukuzawa","year":"2022","journal-title":"Gastroenterol Endosc"},{"key":"key20250227091319_b28-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1007\/s00535-015-1144-2","article-title":"Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: A multicenter retrospective study","volume":"51","author":"Asayama","year":"2016","journal-title":"J Gastroenterol"},{"key":"key20250227091319_b29-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1111\/j.1349-7006.2011.01997.x","article-title":"Risk of lymph node metastasis in patients with pedunculated type early invasive colorectal cancer: A retrospective multicenter study","volume":"102","author":"Matsuda","year":"2011","journal-title":"Cancer Sci"},{"key":"key20250227091319_b30-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1159\/000450942","article-title":"\u2018Head invasion\u2019 is not a metastasis-free condition in pedunculated T1 colorectal carcinoma based on the precise histopathological assessment","volume":"94","author":"Kimura","year":"2016","journal-title":"Digestion"},{"key":"key20250227091319_b31-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1055\/a-0854-5925","article-title":"Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer: European society of gastrointestinal endoscopy (ESGE) and European Society of digestive oncology (ESDO) Guideline","volume":"51","author":"Hassan","year":"2019","journal-title":"Endoscopy"},{"key":"key20250227091319_b32-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.1053\/j.gastro.2020.08.050","article-title":"Endoscopic recognition and management strategies for malignant colorectal polyps: Recommendations of the US multi-society task force on colorectal cancer","volume":"159","author":"Shaukat","year":"2020","journal-title":"Gastroenterology"},{"key":"key20250227091319_b33-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/den.13545","article-title":"Japan gastroenterological endoscopy society guidelines for colorectal endoscopic submucosal dissection\/endoscopic mucosal resection","volume":"32","author":"Tanaka","year":"2020","journal-title":"Dig Endosc"},{"key":"key20250227091319_b34-MI-5-2-00217","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s00535-010-0341-2","article-title":"Characteristics of recurrence after curative resection for T1 colorectal cancer: Japanese multicenter study","volume":"46","author":"Kobayashi","year":"2011","journal-title":"J Gastroenterol"}],"container-title":["Medicine International"],"original-title":[],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T07:14:06Z","timestamp":1740640446000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mi.2025.217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,5]]},"references-count":34,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,5]]}},"URL":"https:\/\/doi.org\/10.3892\/mi.2025.217","relation":{},"ISSN":["2754-3242","2754-1304"],"issn-type":[{"value":"2754-3242","type":"print"},{"value":"2754-1304","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,5]]},"article-number":"18"}}