{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T06:53:35Z","timestamp":1763535215514},"reference-count":27,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.3892\/mmr.2013.1545","type":"journal-article","created":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T11:44:14Z","timestamp":1372160654000},"page":"367-372","source":"Crossref","is-referenced-by-count":6,"title":["Cytotoxic role of advanced glycation end-products in PC12 cells treated with \u03b2-amyloid peptide"],"prefix":"10.3892","volume":"8","author":[{"given":"FU-LING","family":"YAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GUO-LING","family":"HAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GUAN-JIN","family":"WU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2013,6,25]]},"reference":[{"key":"key20180108013805_b1-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00401-010-0654-5","article-title":"Prevalence of dementia disorders in the oldest-old: an autopsy study","volume":"119","author":"Jellinger","year":"2010","journal-title":"Acta Neuropathol"},{"key":"key20180108013805_b2-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1017\/S0317167100013408","article-title":"Amyloid and Alzheimer\u2019s disease: inside and out","volume":"39","author":"Tam","year":"2012","journal-title":"Can J Neurol Sci"},{"key":"key20180108013805_b3-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0167-4889(00)00087-2","article-title":"The biology of the receptor for advanced glycation end products and its ligands","volume":"1498","author":"Schmidt","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"key20180108013805_b4-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/382685a0","article-title":"RAGE and amyloid-beta peptide neurotoxicity in Alzheimer\u2019s disease","volume":"382","author":"Yan","year":"1996","journal-title":"Nature"},{"key":"key20180108013805_b5-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00213-008-1365-7","article-title":"Pharmaceutical treatment for cognitive deficits in Alzheimer\u2019s disease and other neurodegenerative conditions: exploring new territory using traditional tools and established maps","volume":"202","author":"Bartus","year":"2009","journal-title":"Psychopharmacology (Berl)"},{"key":"key20180108013805_b6-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/exnr.2001.7732","article-title":"Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer\u2019s disease: identification of a cellular activation mechanism","volume":"171","author":"Lue","year":"2001","journal-title":"Exp Neurol"},{"key":"key20180108013805_b7-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"833","DOI":"10.3233\/JAD-2009-1030","article-title":"RAGE and Alzheimer\u2019s disease: a progression factor for amyloid-beta-induced cellular perturbation?","volume":"16","author":"Yan","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"key20180108013805_b8-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.exger.2010.11.007","article-title":"Role of advanced glycation end products (AGEs) and receptor for AGEs (RAGE) in vascular damage in diabetes","volume":"46","author":"Yamagishi","year":"2011","journal-title":"Exp Gerontol"},{"key":"key20180108013805_b9-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.neurobiolaging.2009.04.016","article-title":"Advanced glycation endproducts and their receptor RAGE in Alzheimer\u2019s disease","volume":"32","author":"Srikanth","year":"2011","journal-title":"Neurobiol Aging"},{"key":"key20180108013805_b10-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3233\/JAD-2009-0998","article-title":"Regulated proteolysis of RAGE and AbetaPP as possible link between type 2 diabetes mellitus and Alzheimer\u2019s disease","volume":"16","author":"Kojro","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"key20180108013805_b11-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1046\/j.1523-1755.2001.59780032.x","article-title":"Inflammation and advanced glycation end products in uremia: simple coexistence, potentiation or causal relationship?","volume":"78","author":"Schwedler","year":"2001","journal-title":"Kidney Int Suppl"},{"key":"key20180108013805_b12-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1523\/JNEUROSCI.13-04-01676.1993","article-title":"Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state","volume":"13","author":"Pike","year":"1993","journal-title":"J Neurosci"},{"key":"key20180108013805_b13-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1016\/S0021-9258(18)42741-X","article-title":"Immunochemical detection of advanced glycosylation end products in vivo","volume":"267","author":"Makita","year":"1992","journal-title":"J Biol Chem"},{"issue":"Suppl 2","key":"key20180108013805_b14-mmr-08-02-0367","first-page":"S13","article-title":"New insights into the neuropathology and cell biology of Alzheimer\u2019s disease","volume":"52","author":"Weldon","year":"1997","journal-title":"Geriatrics"},{"key":"key20180108013805_b15-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1196\/annals.1433.026","article-title":"Inflammation and the redox-sensitive AGE-RAGE pathway as a therapeutic target in Alzheimer\u2019s disease","volume":"1126","author":"Maczurek","year":"2008","journal-title":"Ann NY Acad Sci"},{"key":"key20180108013805_b16-mmr-08-02-0367","first-page":"734956","article-title":"The complexity of sporadic Alzheimer\u2019s disease pathogenesis: the role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction","volume":"2012","author":"Perrone","year":"2012","journal-title":"Int J Alzheimers Dis"},{"key":"key20180108013805_b17-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"a006338","DOI":"10.1101\/cshperspect.a006338","article-title":"Neurotoxicity of Amyloid \u03b2-Protein: Synaptic and Network Dysfunction","volume":"2","author":"Mucke","year":"2012","journal-title":"Cold Spring Harb Perspect Med"},{"key":"key20180108013805_b18-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1039\/c000789g","article-title":"Microwave-assisted Maillard reactions for the preparation of advanced glycation end products (AGEs)","volume":"8","author":"Visentin","year":"2010","journal-title":"Org Biomol Chem"},{"key":"key20180108013805_b19-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF03401729","article-title":"Receptors for advanced glycosylation endproducts in human brain: role in brain homeostasis","volume":"4","author":"Li","year":"1998","journal-title":"Mol Med"},{"key":"key20180108013805_b20-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ntt.2010.12.002","article-title":"On the in vivo early toxic properties of A-beta 25\u201335 peptide in the rat hippocampus: involvement of the Receptor-for-Advanced Glycation-End-Products and changes in gene expression","volume":"33","author":"Cuevas","year":"2011","journal-title":"Neurotoxicol Teratol"},{"key":"key20180108013805_b21-mmr-08-02-0367","first-page":"489456","article-title":"Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer\u2019s disease","volume":"2012","author":"Wilkinson","year":"2012","journal-title":"Int J Alzheimers Dis"},{"key":"key20180108013805_b22-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s12035-010-8106-8","article-title":"Microglia activation and anti-inflammatory regulation in Alzheimer\u2019s disease","volume":"41","author":"Lue","year":"2010","journal-title":"Mol Neurobiol"},{"key":"key20180108013805_b23-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/WAD.0b013e31823b2728","article-title":"Cerebrospinal fluid cytokine dynamics differ between Alzheimer disease patients and elderly controls","volume":"26","author":"Llano","year":"2012","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"key20180108013805_b24-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"e35125","DOI":"10.1371\/journal.pone.0035125","article-title":"Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-\u03baB pathway in microglia cells","volume":"7","author":"Zhu","year":"2012","journal-title":"PLoS One"},{"key":"key20180108013805_b25-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1096\/fj.09-139634","article-title":"RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning\/memory in a mouse model of Alzheimer\u2019s disease","volume":"24","author":"Fang","year":"2010","journal-title":"FASEB J"},{"key":"key20180108013805_b26-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"39904","DOI":"10.1074\/jbc.M111.267583","article-title":"Neuronal death induced by nanomolar amyloid \u03b2 is mediated by primary phagocytosis of neurons by microglia","volume":"286","author":"Neniskyte","year":"2011","journal-title":"J Biol Chem"},{"key":"key20180108013805_b27-mmr-08-02-0367","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s12017-011-8155-9","article-title":"Oxidative stress and \u03b2-amyloid protein in Alzheimer\u2019s disease","volume":"13","author":"Cai","year":"2011","journal-title":"Neuromolecular Med"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2013.1545\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T07:21:27Z","timestamp":1645860087000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2013.1545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,25]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,6,25]]},"published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.3892\/mmr.2013.1545"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2013.1545","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,25]]}}}