{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T17:08:27Z","timestamp":1785344907361,"version":"3.55.0"},"reference-count":32,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.3892\/mmr.2015.3242","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T13:29:26Z","timestamp":1421933366000},"page":"4285-4290","source":"Crossref","is-referenced-by-count":35,"title":["Quercetin attenuates the effects of H2O2 on endoplasmic reticulum morphology and tyrosinase export from the endoplasmic reticulum in melanocytes"],"prefix":"10.3892","volume":"11","author":[{"given":"CUIPING","family":"GUAN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WEN","family":"XU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WEISONG","family":"HONG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MIAONI","family":"ZHOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FUQUAN","family":"LIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LIFANG","family":"FU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DONGYIN","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AIE","family":"XU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"key":"key20180108002217_b1-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1600-0749.2006.00355.x","article-title":"The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force","volume":"20","author":"Ta\u00efeb","year":"2007","journal-title":"Pigment Cell Res"},{"key":"key20180108002217_b2-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1600-0625.1993.tb00023.x","article-title":"Review of the etiopathomechanism of vitiligo: a convergence theory","volume":"2","author":"Le Poole","year":"1993","journal-title":"Exp Dermatol"},{"key":"key20180108002217_b3-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1159\/000029867","article-title":"Successful treatment of oxidative stress in vitiligo","volume":"12","author":"Schallreuter","year":"1999","journal-title":"Skin Pharmacol Appl Skin Physiol"},{"key":"key20180108002217_b4-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/1523-1747.ep12335801","article-title":"Increased sensitivity to peroxidative agents as a possible pathogenic factor of melanocyte damage in vitiligo","volume":"109","author":"Maresca","year":"1997","journal-title":"J Invest Dermatol"},{"key":"key20180108002217_b5-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1046\/j.0022-202x.2001.01459.x","article-title":"Mitochondrial impairment in peripheral blood mononuclear cells during the active phase of vitiligo","volume":"117","author":"Dell\u2019Anna","year":"2001","journal-title":"J Invest Dermatol"},{"key":"key20180108002217_b6-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/1523-1747.ep12492612","article-title":"Low catalase levels in the epidermis of patients with vitiligo","volume":"97","author":"Schallreuter","year":"1991","journal-title":"J Invest Dermatol"},{"key":"key20180108002217_b7-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"268","DOI":"10.4103\/0378-6323.48427","article-title":"Determination of oxidative stress in vitiligo by measuring superoxide dismutase and catalase levels in vitiliginous and non-vitiliginous skin","volume":"75","author":"Sravani","year":"2009","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"key20180108002217_b8-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"3790","DOI":"10.1096\/fj.09-132621","article-title":"Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage","volume":"23","author":"Salem","year":"2009","journal-title":"FASEB J"},{"key":"key20180108002217_b9-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.mrfmmm.2004.07.005","article-title":"Increased oxidative DNA damage in mononuclear leukocytes in vitiligo","volume":"556","author":"Giovannelli","year":"2004","journal-title":"Mutat Res"},{"key":"key20180108002217_b10-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0749.2007.00399.x","article-title":"Vitiligo puzzle: the pieces fall in place","volume":"20","author":"Westerhof","year":"2007","journal-title":"Pigment Cell Res"},{"key":"key20180108002217_b11-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.bbrc.2004.01.082","article-title":"Activation\/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo","volume":"315","author":"Schallreuter","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"key20180108002217_b12-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/BF02978208","article-title":"Cytoprotective effect of green tea extract and quercetin against hydrogen peroxide-induced oxidative stress","volume":"28","author":"Jeong","year":"2005","journal-title":"Arch Pharm Res"},{"key":"key20180108002217_b13-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1046\/j.1600-0749.2003.00113.x","article-title":"Quercetin enhances melanogenesis by increasing the activity and synthesis of tyrosinase in human melanoma cells and in normal human melanocytes","volume":"17","author":"Nagata","year":"2004","journal-title":"Pigment Cell Res"},{"key":"key20180108002217_b14-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1365-2230.2007.02514.x","article-title":"Antioxidants and narrow band-UVB in the treatment of vitiligo: a double-blind placebo controlled trial","volume":"32","author":"Dell\u2019Anna","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"key20180108002217_b15-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/1523-1747.ep12480976","article-title":"Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients","volume":"97","author":"Boissy","year":"1991","journal-title":"J Invest Dermatol"},{"key":"key20180108002217_b16-mmr-11-06-4285","first-page":"57","article-title":"The role of VIT1\/FBXO11 in the regulation of apoptosis and tyrosinase export from endoplasmic reticulum in cultured melanocytes","volume":"26","author":"Guan","year":"2010","journal-title":"Int J Mol Med"},{"key":"key20180108002217_b17-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1007\/s10571-013-9937-4","article-title":"Olfactory ensheathing cell-conditioned medium protects astrocytes exposed to hydrogen peroxide stress","volume":"33","author":"Jinbo","year":"2013","journal-title":"Cell Mol Neurobiol"},{"key":"key20180108002217_b18-mmr-11-06-4285","first-page":"520","article-title":"Ratio of size of recipient and donor areas in treatment of vitiligo by autologous cultured melanocyte transplantation","volume":"165","author":"Hong","year":"2011","journal-title":"Br J Dermatol"},{"key":"key20180108002217_b19-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.semcdb.2007.09.003","article-title":"The endoplasmic reticulum and the unfolded protein response","volume":"18","author":"Malhotra","year":"2007","journal-title":"Semin Cell Dev Biol"},{"key":"key20180108002217_b20-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nrm2199","article-title":"Signal integration in the endoplasmic reticulum unfolded protein response","volume":"8","author":"Ron","year":"2007","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20180108002217_b21-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2121-11-59","article-title":"Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin","volume":"11","author":"Hartley","year":"2010","journal-title":"BMC Cell Biol"},{"key":"key20180108002217_b22-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1096\/fj.03-1210fje","article-title":"Misfolded proinsulin accumulates in expanded pre-Golgi intermediates and endoplasmic reticulum subdomains in pancreatic beta cells of Akita mice","volume":"18","author":"Zuber","year":"2004","journal-title":"FASEB J"},{"key":"key20180108002217_b23-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1096\/fj.01-0216com","article-title":"Oculocutaneous albinism types 1 and 3 are ER retention diseases: Mutation of tyrosinase or Tyrp1 can affect the processing of both mutant and wild-type proteins","volume":"15","author":"Toyofuku","year":"2001","journal-title":"Faseb J"},{"key":"key20180108002217_b24-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"6210","DOI":"10.1073\/pnas.94.12.6210","article-title":"Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells","volume":"94","author":"Halaban","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180108002217_b25-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"12281","DOI":"10.1074\/jbc.275.16.12281","article-title":"A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature","volume":"275","author":"Berson","year":"2000","journal-title":"J Biol Chem"},{"key":"key20180108002217_b26-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"20332","DOI":"10.1074\/jbc.M300090200","article-title":"The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles","volume":"278","author":"Chiang","year":"2003","journal-title":"J Biol Chem"},{"key":"key20180108002217_b27-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1034\/j.1600-0749.2003.00034.x","article-title":"The Seiji memorial lecture: the melanosome: an ideal model to study cellular differentiation","volume":"16","author":"Kushimoto","year":"2003","journal-title":"Pigment Cell Res"},{"key":"key20180108002217_b28-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.lfs.2003.08.019","article-title":"Green tea metabolite EGCG protects membranes against oxidative damage in vitro","volume":"74","author":"Saffari","year":"2004","journal-title":"Life Sci"},{"key":"key20180108002217_b29-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1034\/j.1600-0749.2000.130312.x","article-title":"The responses of the human epidermal melanocyte system to chronic erythemal doses of UVR in skin protected by topical applications of a combination of vitamins C and E","volume":"13","author":"Quevedo","year":"2000","journal-title":"Pigment Cell Res"},{"key":"key20180108002217_b30-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000080217","article-title":"The combined effects of extracts containing carotenoids and vitamins E and C on growth and pigmentation of cultured human melanocytes","volume":"17","author":"Smit","year":"2004","journal-title":"Skin Pharmacol Physiol"},{"key":"key20180108002217_b31-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/MCO.0b013e32831394b8","article-title":"Quercetin: potentials in the prevention and therapy of disease","volume":"11","author":"Bischoff","year":"2008","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"key20180108002217_b32-mmr-11-06-4285","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.canlet.2008.03.046","article-title":"Multitargeted cancer prevention by quercetin","volume":"269","author":"Murakami","year":"2008","journal-title":"Cancer Lett"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2015.3242\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T18:58:01Z","timestamp":1717700281000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2015.3242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,22]]},"references-count":32,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,1,22]]},"published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.3892\/mmr.2015.3242"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2015.3242","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,22]]}}}