{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:47:29Z","timestamp":1773388049012,"version":"3.50.1"},"reference-count":30,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.3892\/mmr.2015.3742","type":"journal-article","created":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T04:08:00Z","timestamp":1430971680000},"page":"3146-3150","source":"Crossref","is-referenced-by-count":25,"title":["Circulating microRNA-122, -21 and -223 as potential markers of liver injury following warm ischaemia and reperfusion in rats"],"prefix":"10.3892","volume":"12","author":[{"given":"PATRICK","family":"VAN CASTER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TIMO","family":"BRANDENBURGER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"THORSTEN","family":"STRAHL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SABINE","family":"METZGER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"INGE","family":"BAUER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BENEDIKT","family":"PANNEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SEBASTIAN","family":"BRAUN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,5,7]]},"reference":[{"key":"key20180108022411_b1-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.tox.2007.11.021","article-title":"The current state of serum biomarkers of hepatotoxicity","volume":"245","author":"Ozer","year":"2008","journal-title":"Toxicology"},{"key":"key20180108022411_b2-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"10513","DOI":"10.1073\/pnas.0804549105","article-title":"Circulating microRNAs as stable blood-based markers for cancer detection","volume":"105","author":"Mitchell","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180108022411_b3-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1365-2141.2008.07077.x","article-title":"Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma","volume":"141","author":"Lawrie","year":"2008","journal-title":"Br J Haematol"},{"key":"key20180108022411_b4-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mc.20712","article-title":"Circulating microRNAs, miR-21, miR-122 and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis","volume":"50","author":"Xu","year":"2011","journal-title":"Mol Carcinog"},{"key":"key20180108022411_b5-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jhep.2011.04.026","article-title":"Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma","volume":"56","author":"Tomimaru","year":"2012","journal-title":"J Hepatol"},{"key":"key20180108022411_b6-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"4781","DOI":"10.1200\/JCO.2011.38.2697","article-title":"Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma","volume":"29","author":"Zhou","year":"2011","journal-title":"J Clin Oncol"},{"key":"key20180108022411_b7-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1373\/clinchem.2009.131797","article-title":"Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury","volume":"55","author":"Laterza","year":"2009","journal-title":"Clin Chem"},{"key":"key20180108022411_b8-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/hep.26294","article-title":"Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital","volume":"58","author":"Antoine","year":"2013","journal-title":"Hepatology"},{"key":"key20180108022411_b9-mmr-12-02-3146","first-page":"1428","article-title":"Circulating microRNA-122 as a potential biomarker for liver injury","volume":"5","author":"Ding","year":"2012","journal-title":"Mol Med Rep"},{"key":"key20180108022411_b10-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"e73133","DOI":"10.1371\/journal.pone.0073133","article-title":"Circulating liver-specific miR-122 as a novel potential biomarker for diagnosis of cholestatic liver injury","volume":"8","author":"Shifeng","year":"2013","journal-title":"PLoS One"},{"key":"key20180108022411_b11-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/SHK.0b013e31823f1811","article-title":"Plasma levels of liver-specific miR-122 is massively increased in a porcine cardiogenic shock model and attenuated by hypothermia","volume":"37","author":"Andersson","year":"2012","journal-title":"Shock"},{"key":"key20180108022411_b12-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/lt.22438","article-title":"Hepatocyte-derived microRNAs as serum biomarkers of hepatic injury and rejection after liver transplantation","volume":"18","author":"Farid","year":"2012","journal-title":"Liver Transpl"},{"key":"key20180108022411_b13-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.cca.2013.05.021","article-title":"Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver","volume":"424","author":"Yamada","year":"2013","journal-title":"Clin Chim Acta"},{"key":"key20180108022411_b14-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1111\/cas.12300","article-title":"Plasma miR-21 is a novel diagnostic biomarker for biliary tract cancer","volume":"104","author":"Kishimoto","year":"2013","journal-title":"Cancer Sci"},{"key":"key20180108022411_b15-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1007\/s10620-008-0629-8","article-title":"Association of MicroRNA-223 expression with hepatic ischemia\/reperfusion injury in mice","volume":"54","author":"Yu","year":"2009","journal-title":"Dig Dis Sci"},{"key":"key20180108022411_b16-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/cr.2008.282","article-title":"Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases","volume":"18","author":"Chen","year":"2008","journal-title":"Cell Res"},{"key":"key20180108022411_b17-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/abbs\/gmq114","article-title":"Stability analysis of liver cancer-related microRNAs","volume":"43","author":"Li","year":"2011","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"key20180108022411_b18-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/ncb2210","article-title":"MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins","volume":"13","author":"Vickers","year":"2011","journal-title":"Nat Cell Biol"},{"key":"key20180108022411_b19-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"7223","DOI":"10.1093\/nar\/gkr254","article-title":"Characterization of extracellular circulating microRNA","volume":"39","author":"Turchinovich","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"key20180108022411_b20-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1097\/01.sla.0000256891.45790.4d","article-title":"Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia\/reperfusion injury","volume":"245","author":"Schmidt","year":"2007","journal-title":"Ann Surg"},{"key":"key20180108022411_b21-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/SHK.0000000000000125","article-title":"Pretreatment with helium does not attenuate liver injury after warm ischemia reperfusion","volume":"41","author":"Braun","year":"2014","journal-title":"Shock"},{"key":"key20180108022411_b22-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"key20180108022411_b23-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0960-9822(02)00809-6","article-title":"Identification of tissue-specific microRNAs from mouse","volume":"12","author":"Lagos-Quintana","year":"2002","journal-title":"Curr Biol"},{"key":"key20180108022411_b24-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"4402","DOI":"10.1073\/pnas.0813371106","article-title":"Circulating microRNAs, potential biomarkers for drug-induced liver injury","volume":"106","author":"Wang","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180108022411_b25-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1111\/j.1365-2893.2011.01536.x","article-title":"Serum microRNA-122 levels in different groups of patients with chronic hepatitis B virus infection","volume":"19","author":"Waidmann","year":"2012","journal-title":"J Viral Hepat"},{"key":"key20180108022411_b26-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"e23937","DOI":"10.1371\/journal.pone.0023937","article-title":"Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease","volume":"6","author":"Cermelli","year":"2011","journal-title":"PLoS One"},{"key":"key20180108022411_b27-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mc.20712","article-title":"Circulating MicroRNAs, miR-21, miR-122 and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis","volume":"50","author":"Xu","year":"2011","journal-title":"Mol Carcinog"},{"key":"key20180108022411_b28-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.cell.2007.04.040","article-title":"A mammalian microRNA expression atlas based on small RNA library sequencing","volume":"129","author":"Landgraf","year":"2007","journal-title":"Cell"},{"key":"key20180108022411_b29-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.leukres.2005.09.001","article-title":"Hematopoietic-specific microRNA expression in human cells","volume":"30","author":"Ramkissoon","year":"2006","journal-title":"Leuk Res"},{"key":"key20180108022411_b30-mmr-12-02-3146","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/TP.0b013e31827d62b5","article-title":"Intravital imaging of neutrophil recruitment in hepatic ischemia-reperfusion injury in mice","volume":"95","author":"Honda","year":"2013","journal-title":"Transplantation"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2015.3742\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T23:26:55Z","timestamp":1515367615000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2015.3742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,7]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,5,7]]},"published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.3892\/mmr.2015.3742"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2015.3742","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,7]]}}}