{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:45:50Z","timestamp":1777484750608,"version":"3.51.4"},"reference-count":29,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.3892\/mmr.2015.4616","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T13:42:30Z","timestamp":1448545350000},"page":"874-880","source":"Crossref","is-referenced-by-count":16,"title":["Sodium orthovanadate induces the apoptosis of SH-SY5Y cells by inhibiting PIWIL2"],"prefix":"10.3892","volume":"13","author":[{"given":"XIAOHONG","family":"TIAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JUN","family":"FAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WEIJIAN","family":"HOU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHULING","family":"BAI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"QIANG","family":"AO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HAO","family":"TONG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"key20180108024448_b1-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1200\/JCO.1999.17.7.2264","article-title":"Molecular biology of neuroblastoma","volume":"17","author":"Maris","year":"1999","journal-title":"J Clin Oncol"},{"key":"key20180108024448_b2-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(07)60983-0","article-title":"Neuroblastoma","volume":"369","author":"Maris","year":"2007","journal-title":"Lancet"},{"key":"key20180108024448_b3-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1053\/j.semnuclmed.2011.05.001","article-title":"Pediatrics: Diagnosis of neuroblastoma","volume":"41","author":"Sharp","year":"2011","journal-title":"Semin Nucl Med"},{"key":"key20180108024448_b4-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1056\/NEJM199910143411601","article-title":"Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation and 13-cisretinoic acid. Children's Cancer group","volume":"341","author":"Matthay","year":"1999","journal-title":"N Engl J Med"},{"key":"key20180108024448_b5-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S1470-2045(08)70069-X","article-title":"High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: A randomised trial","volume":"9","author":"Pearson","year":"2008","journal-title":"Lancet Oncol"},{"key":"key20180108024448_b6-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1002\/pbc.21713","article-title":"Outcomes of the POG 9340\/9341\/9342 trials for children with high-risk neuroblastoma: A report from the Children's Oncology Group","volume":"51","author":"Zage","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"key20180108024448_b7-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/00043426-200404000-00003","article-title":"Factors influencing survival in children with recurrent neuroblastoma","volume":"26","author":"Lau","year":"2004","journal-title":"J Pediatr Hematol Oncol"},{"key":"key20180108024448_b8-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/pbc.20331","article-title":"Long-term complications in survivors of advanced stage neuroblastoma","volume":"45","author":"Laverdi\u00e8re","year":"2005","journal-title":"Pediatr Blood Cancer"},{"key":"key20180108024448_b9-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3233\/CBM-130360","article-title":"Overexpression of PIWI proteins in human stage III epithelial ovarian cancer with lymph node metastasis","volume":"13","author":"Chen","year":"2013","journal-title":"Cancer Biomark"},{"key":"key20180108024448_b10-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1182\/blood.V97.2.426","article-title":"Human CD34 (+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi","volume":"97","author":"Sharma","year":"2001","journal-title":"Blood"},{"key":"key20180108024448_b11-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.devcel.2007.03.001","article-title":"MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline","volume":"12","author":"Carmell","year":"2007","journal-title":"Dev Cell"},{"key":"key20180108024448_b12-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nature04916","article-title":"A novel class of small RNAs bind to MILI protein in mouse testes","volume":"442","author":"Aravin","year":"2006","journal-title":"Nature"},{"key":"key20180108024448_b13-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"3988","DOI":"10.1038\/sj.onc.1205505","article-title":"Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas","volume":"21","author":"Qiao","year":"2002","journal-title":"Oncogene"},{"key":"key20180108024448_b14-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/j.febslet.2012.03.053","article-title":"PIWIL4 regulates cervical cancer cell line growth and is involved in down-regulating the expression of p14ARF and p53","volume":"586","author":"Su","year":"2012","journal-title":"FEBS Lett"},{"key":"key20180108024448_b15-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/MAJ.0b013e31822cb4cd","article-title":"Combined phenotype of 4 markers improves prognostic value of patients with colon cancer","volume":"343","author":"Liu","year":"2012","journal-title":"Am J Med Sci"},{"key":"key20180108024448_b16-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1258\/ebm.2012.011380","article-title":"Piwil2 modulates the proliferation and metastasis of colon cancer via regulation of matrix metallopeptidase 9 transcriptional activity","volume":"237","author":"Li","year":"2012","journal-title":"Exp Biol Med (Maywood)"},{"key":"key20180108024448_b17-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"195","DOI":"10.18388\/abp.2012_2138","article-title":"Biochemical and medical importance of vanadium compounds","volume":"59","author":"Korbecki","year":"2012","journal-title":"Acta Biochim Pol"},{"key":"key20180108024448_b18-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.canlet.2014.05.018","article-title":"Sodium orthovanadate inhibits growth of human hepatocellular carcinoma cells in vitro and in an orthotopic model in vivo","volume":"351","author":"Wu","year":"2014","journal-title":"Cancer Lett"},{"key":"key20180108024448_b19-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/nature11502","article-title":"The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis","volume":"491","author":"Ipsaro","year":"2012","journal-title":"Nature"},{"key":"key20180108024448_b20-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3409\/fb.56_3-4.115-121","article-title":"Sodium orthovanadate affects growth of some human epithelial cancer cells (A549, HTB44, DU145)","volume":"56","author":"Klein","year":"2008","journal-title":"Folia Biol (Krakow)"},{"key":"key20180108024448_b21-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"key20180108024448_b22-mmr-13-01-0874","first-page":"346","volume-title":"Experimental biochemistry","author":"Dryer","year":"1989"},{"key":"key20180108024448_b23-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1056\/NEJMra0804577","article-title":"Recent advances in neuroblastoma","volume":"362","author":"Maris","year":"2010","journal-title":"N Engl J Med"},{"key":"key20180108024448_b24-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1093\/hmg\/ddi430","article-title":"Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3\/Bcl-XL pathway","volume":"15","author":"Lee","year":"2006","journal-title":"Hum Mol Genet"},{"key":"key20180108024448_b25-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.mrfmmm.2011.02.001","article-title":"Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment","volume":"708","author":"Wang","year":"2011","journal-title":"Mutat Res"},{"key":"key20180108024448_b26-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1016\/j.bbamem.2012.04.012","article-title":"Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate","volume":"1818","author":"Suwalsky","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"key20180108024448_b27-mmr-13-01-0874","first-page":"51","article-title":"Comparison of the effect of VOSO4, Na3VO4 and NaVO3 on proliferation, viability and morphology of H35-19 rat hepatoma cell line","volume":"58","author":"Kordowiak","year":"2007","journal-title":"Pol J Pathol"},{"key":"key20180108024448_b28-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"307102","DOI":"10.5402\/2012\/307102","article-title":"Menadione: Sodium orthovanadate combination eliminates and inhibits migration of detached cancer cells","volume":"2012","author":"Delwar","year":"2012","journal-title":"ISRN Pharmacol"},{"key":"key20180108024448_b29-mmr-13-01-0874","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1038\/sj.onc.1202614","article-title":"Cell cycle dependent subcellular distribution of Cdc25B subtypes","volume":"18","author":"Woo","year":"1999","journal-title":"Oncogene"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2015.4616\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T23:59:35Z","timestamp":1567382375000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2015.4616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,26]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,11,26]]},"published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.3892\/mmr.2015.4616"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2015.4616","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,26]]}}}