{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T03:31:19Z","timestamp":1788838279749,"version":"build-2803163510"},"reference-count":24,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.3892\/mmr.2016.4980","type":"journal-article","created":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T13:33:14Z","timestamp":1457098394000},"page":"3627-3638","source":"Crossref","is-referenced-by-count":24,"title":["Protectin D1 reduces concanavalin A-induced liver injury by inhibiting NF-\u03baB-mediated CX3CL1\/CX3CR1 axis and NLR family, pyrin domain containing 3 inflammasome activation"],"prefix":"10.3892","volume":"13","author":[{"given":"JUN","family":"REN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SHANSHAN","family":"MENG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BINGDI","family":"YAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JINYAN","family":"YU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JING","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2016,3,4]]},"reference":[{"key":"key20180108023548_b1-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1053\/j.gastro.2014.11.040","article-title":"AGA Institute guidelines on hepatitis B reactivation (HBVr): Clinical decision support tool","volume":"148","author":"American Gastroenterological","year":"2015","journal-title":"Gastroenterology"},{"key":"key20180108023548_b2-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"329297","DOI":"10.1155\/2014\/329297","article-title":"Central portalization correlates with fibrosis but not with risk factors for nonalcoholic steatohepatitis in steatotic chronic hepatitis C","volume":"2014","author":"Lee","year":"2014","journal-title":"Int J Hepatol"},{"key":"key20180108023548_b3-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00430-014-0373-y","article-title":"Prophylactic vaccination against hepatitis B: Achievements, challenges and perspectives","volume":"204","author":"Gerlich","year":"2014","journal-title":"Med Microbiol Immunol"},{"key":"key20180108023548_b4-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1002\/hep.27639","article-title":"Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens","volume":"61","author":"Hardtke-Wolenski","year":"2014","journal-title":"Hepatology"},{"key":"key20180108023548_b5-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.jhep.2014.10.018","article-title":"Patient selection based on treatment duration and liver biochemistry increases success rates after treatment withdrawal in autoimmune hepatitis","volume":"62","author":"Hart","year":"2015","journal-title":"J Hepatol"},{"key":"key20180108023548_b6-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"10110","DOI":"10.1021\/jf503188c","article-title":"Protective effect of ellagic acid on concanavalin A-induced hepatitis via toll-like receptor and mitogen-activated protein kinase\/nuclear factor \u03baB signaling pathways","volume":"62","author":"Lee","year":"2014","journal-title":"J Agric Food Chem"},{"key":"key20180108023548_b7-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.intimp.2011.11.005","article-title":"Curcumin attenuates concanavalin A-induced liver injury in mice by inhibition of Toll-like receptor (TLR) 2, TLR4 and TLR9 expression","volume":"12","author":"Tu","year":"2012","journal-title":"Int Immunopharmacol"},{"key":"key20180108023548_b8-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.bcp.2014.06.026","article-title":"Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis","volume":"91","author":"Chen","year":"2014","journal-title":"Biochem Pharmacol"},{"key":"key20180108023548_b9-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nri981","article-title":"Hepatic T cells and liver tolerance","volume":"3","author":"Crispe","year":"3002","journal-title":"Nat Rev Immunol"},{"key":"key20180108023548_b10-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/cmi.2014.116","article-title":"Differential expression of the fractalkine chemokine receptor (CXCR1) in human monocytes during differentiation","volume":"12","author":"Panek","year":"2015","journal-title":"Cell Mol Immunol"},{"key":"key20180108023548_b11-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/hep.20582","article-title":"Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts","volume":"41","author":"Isse","year":"2005","journal-title":"Hepatology"},{"key":"key20180108023548_b12-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"5409","DOI":"10.1073\/pnas.1316510111","article-title":"Pharmacological inhibition of the chemokine receptor CX3CR1 attenuates disease in a chronic-relapsing rat model for multiple sclerosis","volume":"111","author":"Ridderstad Wollberg","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180108023548_b13-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.biocel.2014.01.022","article-title":"Subendothelial resistin enhances monocyte transmigration in a co-culture of human endothelial and smooth muscle cells by mechanisms involving fractalkine, MCP-1 and activation of TLR4 and Gi\/o proteins signaling","volume":"50","author":"Pirvulescu","year":"2014","journal-title":"Int J Biochem Cell Biol"},{"key":"key20180108023548_b14-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1111\/j.1582-4934.2009.00787.x","article-title":"CX3CL1\/fractalkine shedding by human hepatic stellate cells: contribution to chronic inflammation in the liver","volume":"13","author":"Bourd-Boittin","year":"2009","journal-title":"J Cell Mol Med"},{"key":"key20180108023548_b15-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0168-8278(02)00065-X","article-title":"Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans","volume":"37","author":"Efsen","year":"2002","journal-title":"J Hepatol"},{"key":"key20180108023548_b16-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1002\/hep.23795","article-title":"CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice","volume":"52","author":"Aoyama","year":"2010","journal-title":"Hepatology"},{"key":"key20180108023548_b17-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/ana.23928","article-title":"Neuroprotectin\/protectin D1 protects against neuropathic pain in mice after nerve trauma","volume":"74","author":"Xu","year":"2013","journal-title":"Ann Neurol"},{"key":"key20180108023548_b18-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"810","DOI":"10.3760\/cma.j.issn.0366-6999.20131104","article-title":"Protectin D1 promotes resolution of inflammation in a murine model of lipopolysaccharide-induced acute lung injury via enhancing neutrophil apoptosis","volume":"127","author":"Li","year":"2014","journal-title":"Chin Med J (Engl)"},{"key":"key20180108023548_b19-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"5902","DOI":"10.4049\/jimmunol.177.9.5902","article-title":"Resolvin D series and protectin D1 mitigate acute kidney injury","volume":"177","author":"Duffield","year":"2006","journal-title":"J Immunol"},{"key":"key20180108023548_b20-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.immuni.2013.05.015","article-title":"Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation","volume":"38","author":"Yan","year":"2013","journal-title":"Immunity"},{"key":"key20180108023548_b21-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"641865","DOI":"10.1155\/2010\/641865","article-title":"The TLR4\/TRIF-mediated activation of NLRP3 inflammasome underlies endotoxin-induced liver injury in mice","volume":"2010","author":"Tsutsui","year":"2010","journal-title":"Gastroenterol Res Pract"},{"key":"key20180108023548_b22-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"e35523","DOI":"10.1371\/journal.pone.0035523","article-title":"Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis","volume":"7","author":"Zhu","year":"2012","journal-title":"PLoS One"},{"key":"key20180108023548_b23-mmr-13-04-3627","doi-asserted-by":"crossref","DOI":"10.1186\/1742-2094-10-1","article-title":"Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo","volume":"10","author":"Kato","year":"2013","journal-title":"J Neuroinflam"},{"key":"key20180108023548_b24-mmr-13-04-3627","doi-asserted-by":"crossref","first-page":"751374","DOI":"10.1155\/2013\/751374","article-title":"Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice","volume":"2013","author":"DeSantis","year":"2013","journal-title":"Mediators Inflamm"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2016.4980\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T19:43:45Z","timestamp":1718394225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2016.4980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,4]]},"references-count":24,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,3,4]]},"published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.3892\/mmr.2016.4980"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2016.4980","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,4]]}}}