{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:52:38Z","timestamp":1790607158590,"version":"4.1.0"},"reference-count":22,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.3892\/mmr.2016.5822","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T03:24:41Z","timestamp":1476156281000},"page":"4537-4544","source":"Crossref","is-referenced-by-count":34,"title":["Effect of Salvia miltiorrhiza and ligustrazine injection on myocardial ischemia\/reperfusion and hypoxia\/reoxygenation injury"],"prefix":"10.3892","volume":"14","author":[{"given":"Wendong","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Banghao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2016,10,11]]},"reference":[{"key":"key20180108025915_b1-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jep.2014.08.023","article-title":"Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia\/reperfusion injury via the Akt-eNOS signaling pathway in rats","volume":"156","author":"Ren-an","year":"2014","journal-title":"J Ethnopharmacol"},{"key":"key20180108025915_b2-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1038\/3218","article-title":"The global burden of disease, 1990\u20132020","volume":"4","author":"Lopez","year":"1998","journal-title":"Nat Med"},{"key":"key20180108025915_b3-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jjcc.2008.07.016","article-title":"Myocardial ischemia: Current concepts and future perspectives","volume":"52","author":"Shimokawa","year":"2008","journal-title":"J Cardiol"},{"issue":"19","key":"key20180108025915_b4-mmr-14-05-4537","first-page":"II365","article-title":"Platelet-activating factor acetylhydrolase prevents myocardial ischemia-reperfusion injury","volume":"100","author":"Morgan","year":"1999","journal-title":"Circulation"},{"key":"key20180108025915_b5-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10495-011-0671-4","article-title":"Ginsenoside-Rd potentiates apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through the mitochondrial pathway","volume":"17","author":"Li","year":"2012","journal-title":"Apoptosis"},{"key":"key20180108025915_b6-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"e70956","DOI":"10.1371\/journal.pone.0070956","article-title":"Ginsenoside Rd attenuates myocardial ischemia\/reperfusion injury via Akt\/GSK-3\u03b2 signaling and inhibition of the mitochondria-dependent apoptotic pathway","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"key20180108025915_b7-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ejcts.2008.05.035","article-title":"Low dose cyclophosphamide rescues myocardial function from ischemia-reperfusion in rats","volume":"34","author":"Zhu","year":"2008","journal-title":"Eur J Cardiothorac Surg"},{"key":"key20180108025915_b8-mmr-14-05-4537","first-page":"1089","article-title":"Salvia miltiorrhiza and ischemic diseases","volume":"21","author":"Ji","year":"2000","journal-title":"Acta Pharmacol Sin"},{"key":"key20180108025915_b9-mmr-14-05-4537","first-page":"226","article-title":"Effect of danshensu on isolated swine coronary artery perfusion preparation (author's transl)","volume":"17","author":"Dong","year":"1982","journal-title":"Yao Xue Xue Bao"},{"key":"key20180108025915_b10-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.vph.2006.10.011","article-title":"Relaxant effects of danshen aqueous extract and its constituent danshensu on rat coronary artery are mediated by inhibition of calcium channels","volume":"46","author":"Lam","year":"2007","journal-title":"Vascul Pharmacol"},{"key":"key20180108025915_b11-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.phymed.2007.07.060","article-title":"Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats","volume":"14","author":"Wu","year":"2007","journal-title":"Phytomedicine"},{"key":"key20180108025915_b12-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1142\/S0192415X0700548X","article-title":"Tetramethylpyrazine inhibits angiotensin II-increased NAD(P)H oxidase activity and subsequent proliferation in rat aortic smooth muscle cells","volume":"35","author":"Wong","year":"2007","journal-title":"Am J Chin Med"},{"key":"key20180108025915_b13-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jss.2009.04.005","article-title":"The protective mechanism of ligustrazine against renal ischemia\/reperfusion injury","volume":"166","author":"Feng","year":"2011","journal-title":"J Surg Res"},{"key":"key20180108025915_b14-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1358\/mf.2010.32.9.1444768","article-title":"Protective effects of ligustrazine, kakonein and Panax notoginsenosides on multiple organs in rats with severe acute pancreatitis","volume":"32","author":"Zhang","year":"2010","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"key20180108025915_b15-mmr-14-05-4537","first-page":"432","article-title":"Synergism of salviamiltiorriza bunge and tetramethylpyrazine on cardiovascular system in rat","author":"Huang","year":"2013","journal-title":"Chinese Pharmacological Bulletin"},{"key":"key20180108025915_b16-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"8031","DOI":"10.1073\/pnas.92.17.8031","article-title":"Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion","volume":"92","author":"Buerke","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20180108025915_b17-mmr-14-05-4537","first-page":"112","article-title":"Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation","volume":"37","author":"Miki","year":"2001","journal-title":"J Cardiol"},{"key":"key20180108025915_b18-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1161\/01.CIR.103.2.296","article-title":"Low-energy laser irradiation reduces formation of scar tissue after myocardial infarction in rats and dogs","volume":"103","author":"Oron","year":"2001","journal-title":"Circulation"},{"key":"key20180108025915_b19-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0167-5273(02)00189-4","article-title":"Oxidative stress and neutrophil activation-the two keystones of ischemia\/reperfusion injury","volume":"86","author":"Kaminski","year":"2002","journal-title":"Int J Cardiol"},{"key":"key20180108025915_b20-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cardiores.2003.09.019","article-title":"Nitric oxide in myocardial ischemia\/reperfusion injury","volume":"61","author":"Schulz","year":"2004","journal-title":"Cardiovasc Res"},{"key":"key20180108025915_b21-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.freeradbiomed.2007.05.004","article-title":"Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase","volume":"43","author":"Thirunavukkarasu","year":"2007","journal-title":"Free Radic Biol Med"},{"key":"key20180108025915_b22-mmr-14-05-4537","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1152\/japplphysiol.00642.2007","article-title":"Preconditioning and postconditioning: Innate cardioprotection from ischemia-reperfusion injury","volume":"103","author":"Vinten-Johansen","year":"2007","journal-title":"J Appl Physiol (1985)"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2016.5822\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T00:17:27Z","timestamp":1515370647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2016.5822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,11]]},"references-count":22,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,10,11]]},"published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.3892\/mmr.2016.5822"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2016.5822","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,11]]}}}