{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T22:28:06Z","timestamp":1768256886953,"version":"3.49.0"},"reference-count":27,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.3892\/mmr.2017.6276","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T09:30:22Z","timestamp":1488360622000},"page":"2273-2279","source":"Crossref","is-referenced-by-count":19,"title":["1,25(OH)2D3\/VDR attenuates high glucose-induced epithelial-mesenchymal transition in human peritoneal mesothelial cells via the TGF\u03b2\/Smad3 pathway"],"prefix":"10.3892","volume":"15","author":[{"given":"Lina","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2017,3,1]]},"reference":[{"key":"key20180108014905_b1-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1681\/ASN.V132470","article-title":"Peritoneal Biopsy Study Group: Morphologic changes in the peritoneal membrane of patients with renal disease","volume":"13","author":"Williams","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"key20180108014905_b2-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"368","DOI":"10.2174\/1566524015666150505162015","article-title":"Numb induces E-cadherin adhesion dissolution, cytoskeleton reorganization, and migration in tubular epithelial cells contributing to renal fibrosis","volume":"15","author":"Ding","year":"2015","journal-title":"Curr Mol Med"},{"key":"key20180108014905_b3-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"2706","DOI":"10.1002\/jcp.24995","article-title":"Loss of microRNA-101 promotes epithelial to mesenchymal transition in hepatocytes","volume":"230","author":"Zhao","year":"2015","journal-title":"J Cell Physiol"},{"key":"key20180108014905_b4-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"357","DOI":"10.15252\/emmm.201570010","article-title":"Caveolin-1 deficiency induces a MEK-ERK1\/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis","volume":"7","author":"Strippoli","year":"2015","journal-title":"EMBO Mol Med"},{"key":"key20180108014905_b5-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"e108593","DOI":"10.1371\/journal.pone.0108593","article-title":"Serum response factor accelerates the high glucose-induced Epithelial-to-Mesenchymal Transition (EMT) via snail signaling in human peritoneal mesothelial cells","volume":"9","author":"He","year":"2014","journal-title":"PLoS One"},{"key":"key20180108014905_b6-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrm1835","article-title":"Complex networks orchestrate epithelial-mesenchymal transitions","volume":"7","author":"Thiery","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20180108014905_b7-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s12011-014-0091-8","article-title":"Selenium suppresses lipopolysaccharide- induced fibrosis in peritoneal mesothelial cells through inhibition of epithelial-to-mesenchymal transition","volume":"161","author":"Liu","year":"2014","journal-title":"Biol Trace Elem Res"},{"key":"key20180108014905_b8-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1681\/ASN.2008040424","article-title":"Hgf and bmp-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium","volume":"20","author":"Yu","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"key20180108014905_b9-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s12011-012-9451-4","article-title":"Zinc supplementation attenuates high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells","volume":"150","author":"Zhang","year":"2012","journal-title":"Biol Trace Elem Res"},{"key":"key20180108014905_b10-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3389\/fendo.2013.00007","article-title":"Diabetic nephropathy: The role of inflammation in fibroblast activation and kidney fibrosis","volume":"4","author":"Kanasaki","year":"2013","journal-title":"Front Endocrinol (Lausanne)"},{"key":"key20180108014905_b11-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.steroids.2008.06.010","article-title":"Side-chain modified vitamin D analogs induce rapid accumulation of VDR in the cell nuclei proportionately to their differentiation-inducing potential","volume":"73","author":"Gocek","year":"2008","journal-title":"Steroids"},{"key":"key20180108014905_b12-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"e63186","DOI":"10.1371\/journal.pone.0063186","article-title":"Paricalcitol attenuates 4-hydroxy-2-hexenal-induced inflammation and epithelial-mesenchymal transition in human renal proximal tubular epithelial cells","volume":"8","author":"Kim","year":"2013","journal-title":"PLoS One"},{"key":"key20180108014905_b13-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12931-014-0146-6","article-title":"Vitamin D regulating TGF-\u03b2 induced epithelial-mesenchymal transition","volume":"15","author":"Fischer","year":"2014","journal-title":"Respir Res"},{"key":"key20180108014905_b14-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cellimm.2011.06.017","article-title":"Effect of 1,25(OH)(2)D(3) on rat peritoneal mesothelial cells treated with high glucose plus lipopolysaccharide","volume":"271","author":"Yang","year":"2011","journal-title":"Cell Immunol"},{"key":"key20180108014905_b15-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1159\/000142529","article-title":"The role of the TGF\/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions","volume":"109","author":"Yao","year":"2008","journal-title":"Nephron Exp Nephrol"},{"key":"key20180108014905_b16-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1139\/cjpp-2014-0275","article-title":"Spontaneous liver fibrosis induced by long term dietary vitamin D deficiency in adult mice is related to chronic inflammation and enhanced apoptosis","volume":"93","author":"Zhu","year":"2015","journal-title":"Can J Physiol Pharmacol"},{"key":"key20180108014905_b17-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1024\/0300-9831\/a000156","article-title":"Effects of vitamin E, C and D supplementation on inflammation and oxidative stress in streptozotocin-induced diabetic mice","volume":"83","author":"Gre\u0144","year":"2013","journal-title":"Int J Vitam Nutr Res"},{"key":"key20180108014905_b18-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1158\/1940-6207.CAPR-14-0449","article-title":"Effect of Vitamin D3 supplementation in combination with weight loss on inflammatory biomarkers in postmenopausal women: a randomized controlled trial","volume":"8","author":"Duggan","year":"2015","journal-title":"Cancer Prev Res (Phila)"},{"key":"key20180108014905_b19-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.ajpath.2013.05.019","article-title":"miR-30a negatively regulates TGF-\u03b21-induced epithelial-mesenchymal transition and peritoneal fibrosis by targeting Snai1","volume":"183","author":"Zhou","year":"2013","journal-title":"Am J Pathol"},{"key":"key20180108014905_b20-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"F1107","DOI":"10.1152\/ajprenal.00151.2012","article-title":"Loss of vitamin D receptor in chronic kidney disease: A potential mechanism linking inflammation to epithelial-to-mesenchymal transition","volume":"303","author":"Xiong","year":"2012","journal-title":"Am J Physiol Renal Physiol"},{"key":"key20180108014905_b21-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.3390\/cancers5041504","article-title":"1,25-dihydroxyvitamin D3 (1,25(OH)2D3) signaling capacity and the epithelial-mesenchymal transition in non-small cell lung cancer (NSCLC): Implications for Use of 1,25(OH)2D3 in NSCLC treatment","volume":"5","author":"Upadhyay","year":"2013","journal-title":"Cancers (Basel)"},{"key":"key20180108014905_b22-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.2174\/1381612821666141211151138","article-title":"Vitamin D receptor signaling and pancreatic cancer cell EMT","volume":"21","author":"Li","year":"2015","journal-title":"Curr Pharm Des"},{"key":"key20180108014905_b23-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1681\/ASN.2006111292","article-title":"Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: Pathologic significance and potential therapeutic interventions","volume":"18","author":"Aroeira","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"key20180108014905_b24-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1038\/sj.ki.5002598","article-title":"Epithelial-to-mesenchymal transition of mesothelial cells is an early event during peritoneal dialysis and is associated with high peritoneal transport","author":"Del Peso","year":"2008","journal-title":"Kidney Int Suppl"},{"key":"key20180108014905_b25-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/ki.2011.305","article-title":"Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis","volume":"81","author":"Yokoi","year":"2012","journal-title":"Kidney Int"},{"key":"key20180108014905_b26-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1159\/000232937","article-title":"Association between markers of inflammation, fibrosis and hypervolemia in peritoneal dialysis patients","volume":"28","author":"Gangji","year":"2009","journal-title":"Blood Purif"},{"key":"key20180108014905_b27-mmr-15-04-2273","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ijcard.2014.02.041","article-title":"Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts","volume":"173","author":"Lee","year":"2014","journal-title":"Int J Cardiol"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/mmr.2017.6276\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:09:43Z","timestamp":1658707783000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2017.6276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,3,1]]},"published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.3892\/mmr.2017.6276"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2017.6276","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]}}}