{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:01:20Z","timestamp":1791907280074,"version":"4.3.4"},"reference-count":30,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.3892\/mmr.2017.7015","type":"journal-article","created":{"date-parts":[[2017,7,15]],"date-time":"2017-07-15T07:58:39Z","timestamp":1500105519000},"page":"3034-3040","source":"Crossref","is-referenced-by-count":15,"title":["PTPRQ as a potential biomarker for idiopathic normal pressure hydrocephalus"],"prefix":"10.3892","volume":"16","author":[{"given":"Yuki","family":"Nagata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Bundo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saiko","family":"Sugiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kamita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumiko","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Ichi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Urakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumpei","family":"Niida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2017,7,15]]},"reference":[{"key":"key20180108002454_b1-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1056\/NEJM196507152730301","article-title":"Symptomatic occult hydrocephalus with normal cerebrospinal-fluid pressure","volume":"273","author":"Adams","year":"1965","journal-title":"New Engl J Med"},{"key":"key20180108002454_b2-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1002\/jmri.20684","article-title":"Idiopathic normal pressure hydrocephalus may be a \u2018two hit\u2019 disease: Benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood","volume":"24","author":"Bradley","year":"2006","journal-title":"J Magn Reson Imaging"},{"key":"key20180108002454_b3-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1017\/S031716710001146X","article-title":"Normal-pressure hydrocephalus: Is there a genetic predisposition?","volume":"38","author":"Cusimano","year":"2011","journal-title":"Can J Neurol Sci"},{"key":"key20180108002454_b4-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jns.2011.06.018","article-title":"Familial normal pressure hydrocephalus (NPH) with an autosomal-dominant inheritance: A novel subgroup of NPH","volume":"308","author":"Takahashi","year":"2011","journal-title":"J Neurol Sci"},{"key":"key20180108002454_b5-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.ajhg.2010.02.015","article-title":"Mutations in PTPRQ are a cause of autosomal-recessive nonsyndromic hearing impairment DFNB84 and associated with vestibular dysfunction","volume":"86","author":"Schraders","year":"2010","journal-title":"Am J Hum Genet"},{"key":"key20180108002454_b6-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1136\/jmg.2009.075697","article-title":"Nonsense mutation of the stereociliar membrane protein gene PTPRQ in human hearing loss DFNB84","volume":"47","author":"Shahin","year":"2010","journal-title":"J Med Genet"},{"key":"key20180108002454_b7-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1523\/JNEUROSCI.3635-11.2012","article-title":"Hair-bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase, PTPRQ","volume":"32","author":"Goodyear","year":"2012","journal-title":"J Neurosci"},{"key":"key20180108002454_b8-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/dneu.20831","article-title":"Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear","volume":"71","author":"Nayak","year":"2011","journal-title":"Dev Neurobiol"},{"key":"key20180108002454_b9-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1177\/0194599811431234","article-title":"Hydrocephalus-associated hearing loss and resolution after ventriculostomy","volume":"146","author":"Dixon","year":"2012","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key20180108002454_b10-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3171\/2009.4.PEDS09103","article-title":"Resolution of hydrocephalus-associated sensorineural hearing loss after insertion of ventriculoperitoneal shunt","volume":"4","author":"Sammons","year":"2009","journal-title":"J Neurosurg Pediatr"},{"key":"key20180108002454_b11-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"432","DOI":"10.3171\/jns.2001.95.3.0432","article-title":"Analysis of hearing loss after shunt placement in patients with normal-pressure hydrocephalus","volume":"95","author":"van Veelen-Vincent","year":"2001","journal-title":"J Neurosurg"},{"key":"key20180108002454_b12-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"775","DOI":"10.2176\/nmc.52.775","article-title":"Guidelines for management of idiopathic normal pressure hydrocephalus: Second edition","volume":"52","author":"Mori","year":"2012","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"key20180108002454_b13-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000111149","article-title":"Validation of grading scale for evaluating symptoms of idiopathic normal-pressure hydrocephalus","volume":"25","author":"Kubo","year":"2008","journal-title":"Dement Geriatr Cogn Disord"},{"key":"key20180108002454_b14-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S1474-4422(07)70178-3","article-title":"Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS-ADRDA criteria","volume":"6","author":"Dubois","year":"2007","journal-title":"Lancet Neurol"},{"key":"key20180108002454_b15-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1200\/JCO.2008.19.9745","article-title":"Identification of a predictive biomarker for hematologic toxicities of gemcitabine","volume":"27","author":"Matsubara","year":"2009","journal-title":"J Clin Oncol"},{"key":"key20180108002454_b16-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"29041","DOI":"10.1074\/jbc.M109.041749","article-title":"Prolyl 4-hydroxylation of alpha-fibrinogen: A novel protein modification revealed by plasma proteomics","volume":"284","author":"Ono","year":"2009","journal-title":"J Biol Chem"},{"key":"key20180108002454_b17-mmr-16-03-3034","first-page":"768190","article-title":"Carbonic anhydrase I as a new plasma biomarker for prostate cancer","volume":"2012","author":"Takakura","year":"2012","journal-title":"ISRN Oncol"},{"key":"key20180108002454_b18-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1074\/mcp.T500039-MCP200","article-title":"Label-free quantitative proteomics using large peptide data sets generated by nanoflow liquid chromatography and mass spectrometry","volume":"5","author":"Ono","year":"2006","journal-title":"Mol Cell Proteomics"},{"key":"key20180108002454_b19-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/bms.1200220605","article-title":"Use of mass spectrometric molecular weight information to identify proteins in sequence databases","volume":"22","author":"Mann","year":"1993","journal-title":"Biol Mass Spectrom"},{"key":"key20180108002454_b20-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S0014-4827(03)00121-6","article-title":"PTPRQ is a novel phosphatidylinositol phosphatase that can be expressed as a cytoplasmic protein or as a subcellularly localized receptor-like protein","volume":"287","author":"Seifert","year":"2003","journal-title":"Exp Cell Res"},{"key":"key20180108002454_b21-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.neurobiolaging.2011.02.023","article-title":"A unique N-glycan on human transferrin in CSF: A possible biomarker for iNPH","volume":"33","author":"Futakawa","year":"2012","journal-title":"Neurobiol Aging"},{"key":"key20180108002454_b22-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3171\/jns.1983.59.3.0369","article-title":"Recent research into the nature of cerebrospinal fluid formation and absorption","volume":"59","author":"McComb","year":"1983","journal-title":"J Neurosurg"},{"key":"key20180108002454_b23-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3389\/fncel.2015.00039","article-title":"Cilia in the choroid plexus: Their roles in hydrocephalus and beyond","volume":"9","author":"Narita","year":"2015","journal-title":"Front Cell Neurosci"},{"key":"key20180108002454_b24-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"5329","DOI":"10.1242\/dev.02153","article-title":"Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus","volume":"132","author":"Banizs","year":"2005","journal-title":"Development"},{"key":"key20180108002454_b25-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"20131189","DOI":"10.1098\/rsif.2013.1189","article-title":"Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles","volume":"11","author":"Siyahhan","year":"2014","journal-title":"J R Soc Interface"},{"key":"key20180108002454_b26-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1093\/hmg\/ddh219","article-title":"Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation","volume":"13","author":"Iba\u00f1ez-Tallon","year":"2004","journal-title":"Hum Mol Genet"},{"key":"key20180108002454_b27-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1083\/jcb.200710162","article-title":"Mutations in Hydin impair ciliary motility in mice","volume":"180","author":"Lechtreck","year":"2008","journal-title":"J Cell Biol"},{"key":"key20180108002454_b28-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1002\/jnr.23238","article-title":"Riding the wave of ependymal cilia: Genetic susceptibility to hydrocephalus in primary ciliary dyskinesia","volume":"91","author":"Lee","year":"2013","journal-title":"J Neurosci Res"},{"key":"key20180108002454_b29-mmr-16-03-3034","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nn.2555","article-title":"Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus","volume":"13","author":"Tissir","year":"2010","journal-title":"Nat Neurosci"},{"key":"key20180108002454_b30-mmr-16-03-3034","first-page":"1332","article-title":"Endolymphatic hydrops and CSF pressure","volume":"60","author":"Gordon","year":"1984","journal-title":"J Neurosurg"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"language":"en","deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T01:04:38Z","timestamp":1515373478000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/mmr.2017.7015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":30,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,7,15]]},"published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.3892\/mmr.2017.7015"],"URL":"https:\/\/doi.org\/10.3892\/mmr.2017.7015","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]}}}