{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T09:57:41Z","timestamp":1712656661849},"reference-count":50,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Report"],"DOI":"10.3892\/mmr.2017.8348","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T09:15:03Z","timestamp":1514366103000},"source":"Crossref","is-referenced-by-count":4,"title":["MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11"],"prefix":"10.3892","author":[{"given":"Liedao","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Orthopedics Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangjin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengcheng","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2017,12,27]]},"reference":[{"key":"key20200713224201_b1-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"key20200713224201_b2-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/S0140-6736(05)78179-4","article-title":"Trends in primary liver cancer","volume":"351","author":"Deuffic","year":"1998","journal-title":"Lancet"},{"key":"key20200713224201_b3-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1038\/ajg.2014.11","article-title":"Changing hepatocellular carcinoma incidence and liver cancer mortality rates in the United States","volume":"109","author":"Altekruse","year":"2014","journal-title":"Am J Gastroenterol"},{"key":"key20200713224201_b4-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1111\/j.1440-1746.2005.03919.x","article-title":"Clinical features of hepatocellular carcinoma with extrahepatic metastases","volume":"20","author":"Natsuizaka","year":"2005","journal-title":"J Gastroenterol Hepatol"},{"key":"key20200713224201_b5-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1056\/NEJMra030831","article-title":"Mechanisms of bone metastasis","volume":"350","author":"Roodman","year":"2004","journal-title":"N Engl J Med"},{"key":"key20200713224201_b6-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"2710","DOI":"10.1002\/cncr.24300","article-title":"Clinical features and prognostic factors in patients with bone metastases from hepatocellular carcinoma receiving external beam radiotherapy","volume":"115","author":"He","year":"2009","journal-title":"Cancer"},{"key":"key20200713224201_b7-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: Target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"key20200713224201_b8-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"467","DOI":"10.2174\/1389557515666150324123208","article-title":"MicroRNA therapeutics: The next magic bullet?","volume":"6","author":"Simonson","year":"2015","journal-title":"Mini Rev Med Chem"},{"key":"key20200713224201_b9-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1038\/nrg1379","article-title":"MicroRNAs: Small RNAs with a big role in gene regulation","volume":"5","author":"He","year":"2004","journal-title":"Nat Rev Genet"},{"key":"key20200713224201_b10-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1146\/annurev.med.59.053006.104707","article-title":"MicroRNAs in cancer","volume":"60","author":"Garzon","year":"2009","journal-title":"Annu Rev Med"},{"key":"key20200713224201_b11-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1038\/sj.bjc.6606010","article-title":"The role of microRNAs in liver cancer progression","volume":"104","author":"Huang","year":"2011","journal-title":"Br J Cancer"},{"key":"key20200713224201_b12-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1002\/hep.22806","article-title":"MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma","volume":"49","author":"Tsai","year":"2009","journal-title":"Hepatology"},{"key":"key20200713224201_b13-mmr-17-03-3972","first-page":"1660","article-title":"miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma","volume":"27","author":"Zhu","year":"2012","journal-title":"Oncol Rep"},{"key":"key20200713224201_b14-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1038\/onc.2009.468","article-title":"TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3","volume":"29","author":"Wang","year":"2010","journal-title":"Oncogene"},{"key":"key20200713224201_b15-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1002\/path.2877","article-title":"miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened","volume":"225","author":"Huang","year":"2011","journal-title":"J Pathol"},{"key":"key20200713224201_b16-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1111\/liv.12190","article-title":"MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition","volume":"33","author":"Zhou","year":"2013","journal-title":"Liver Int"},{"key":"key20200713224201_b17-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"e91566","DOI":"10.1371\/journal.pone.0091566","article-title":"The tumor suppressor role of miR-124 in osteosarcoma","volume":"9","author":"Geng","year":"2014","journal-title":"PLoS One"},{"key":"key20200713224201_b18-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s11010-013-1913-2","article-title":"miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3","volume":"388","author":"Li","year":"2014","journal-title":"Mol Cell Biochem"},{"key":"key20200713224201_b19-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"e0116197","DOI":"10.1371\/journal.pone.0116197","article-title":"Regulation and methylation of tumor suppressor miR-124 by androgen receptor in prostate cancer cells","volume":"10","author":"Chu","year":"2015","journal-title":"PLoS One"},{"key":"key20200713224201_b20-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"2555","DOI":"10.1007\/s12035-017-0682-4","article-title":"miR-124 Acts as a tumor suppressor in glioblastoma via the inhibition of signal transducer and activator of transcription 3","volume":"54","author":"Li","year":"2017","journal-title":"Mol Neurobiol"},{"key":"key20200713224201_b21-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1002\/hep.22160","article-title":"Identification of metastasis-related microRNAs in hepatocellular carcinoma","volume":"47","author":"Budhu","year":"2008","journal-title":"Hepatology"},{"key":"key20200713224201_b22-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"6001","DOI":"10.1007\/s11033-011-1413-y","article-title":"Expression of connective tissue growth factor and interleukin-11 in intratumoral tissue is associated with poor survival after curative resection of hepatocellular carcinoma","volume":"39","author":"Xiang","year":"2012","journal-title":"Mol Biol Rep"},{"key":"key20200713224201_b23-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"13743","DOI":"10.1074\/jbc.M112.349167","article-title":"Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling","volume":"287","author":"Sommer","year":"2012","journal-title":"J Biol Chem"},{"key":"key20200713224201_b24-mmr-17-03-3972","first-page":"3794","article-title":"Inhibition of connective tissue growth factor overexpression decreases growth of hepatocellular carcinoma cells in vitro and in vivo","volume":"124","author":"Jia","year":"2011","journal-title":"Chin Med J (Engl)"},{"key":"key20200713224201_b25-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1007\/s00432-012-1370-4","article-title":"Enhanced production of CTGF and IL-11 from highly metastatic hepatoma cells under hypoxic conditions: An implication of hepatocellular carcinoma metastasis to bone","volume":"139","author":"Gao","year":"2013","journal-title":"J Cancer Res Clin Oncol"},{"key":"key20200713224201_b26-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1158\/1055-9965.EPI-14-0669","article-title":"Solid tumors of childhood display specific serum microRNA profiles","volume":"24","author":"Murray","year":"2015","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20200713224201_b27-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"3271","DOI":"10.1016\/j.febslet.2012.06.049","article-title":"Epigenetic regulation of miR-124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3","volume":"586","author":"Zeng","year":"2012","journal-title":"FEBS Lett"},{"key":"key20200713224201_b28-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1016\/j.cell.2009.05.038","article-title":"New hope for a microRNA therapy for liver cancer","volume":"137","author":"Rossi","year":"2009","journal-title":"Cell"},{"key":"key20200713224201_b29-mmr-17-03-3972","first-page":"1967","article-title":"Down-regulation of microRNA-124 is correlated with tumor metastasis and poor prognosis in patients with lung cancer","volume":"8","author":"Zhang","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"key20200713224201_b30-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1186\/1476-4598-13-186","article-title":"miR-124 suppresses tumor growth and metastasis by targeting Foxq1 in nasopharyngeal carcinoma","volume":"13","author":"Peng","year":"2014","journal-title":"Mol Cancer"},{"key":"key20200713224201_b31-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.cell.2010.03.015","article-title":"Matrix metalloproteinases: Regulators of the tumor microenvironment","volume":"141","author":"Kessenbrock","year":"2010","journal-title":"Cell"},{"key":"key20200713224201_b32-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/S0168-8278(97)80425-4","article-title":"In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis","volume":"26","author":"Musso","year":"1997","journal-title":"J Hepatol"},{"key":"key20200713224201_b33-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1158\/0008-5472.CAN-14-1589","article-title":"CYP3A5 functions as a tumor suppressor in hepatocellular carcinoma by regulating mTORC2\/Akt signaling","volume":"75","author":"Jiang","year":"2015","journal-title":"Cancer Res"},{"key":"key20200713224201_b34-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.dci.2016.06.018","article-title":"Expression of Bcl-2 genes in channel catfish after bacterial infection and hypoxia stress","volume":"65","author":"Yuan","year":"2016","journal-title":"Dev Comp Immunol"},{"key":"key20200713224201_b35-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1002\/ijc.28062","article-title":"The presence of Merkel cell polyomavirus is associated with deregulated expression of BRAF and Bcl-2 genes in non-small cell lung cancer","volume":"133","author":"Lasithiotaki","year":"2013","journal-title":"Int J Cancer"},{"key":"key20200713224201_b36-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1042\/bj3260001","article-title":"Caspases: The executioners of apoptosis","volume":"326","author":"Cohen","year":"1997","journal-title":"Biochem J"},{"key":"key20200713224201_b37-mmr-17-03-3972","first-page":"S1693","article-title":"BCL-2 gene family and the regulation of programmed cell death","volume":"59","author":"Korsmeyer","year":"1999","journal-title":"Cancer Res"},{"key":"key20200713224201_b38-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"11467","DOI":"10.1007\/s13277-014-2459-y","article-title":"Plasma interleukin-11 (IL-11) levels have diagnostic and prognostic roles in patients with pancreatic cancer","volume":"35","author":"Ren","year":"2014","journal-title":"Tumour Biol"},{"key":"key20200713224201_b39-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1186\/s12885-015-1366-y","article-title":"MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11","volume":"15","author":"Zhou","year":"2015","journal-title":"BMC Cancer"},{"key":"key20200713224201_b40-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1111\/cas.12638","article-title":"High expression of interleukin-11 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma","volume":"106","author":"Pan","year":"2015","journal-title":"Cancer Sci"},{"key":"key20200713224201_b41-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1634\/theoncologist.2010-0358","article-title":"Potential prognostic biomarkers for bone metastasis from hepatocellular carcinoma","volume":"16","author":"Xiang","year":"2011","journal-title":"Oncologist"},{"key":"key20200713224201_b42-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"3039","DOI":"10.3892\/ol.2017.5846","article-title":"Reduced RKIP expression levels are associated with frequent non-small cell lung cancermetastasis and STAT3 phosphorylation and activation","volume":"13","author":"Wang","year":"2017","journal-title":"Oncol Lett"},{"key":"key20200713224201_b43-mmr-17-03-3972","doi-asserted-by":"crossref","first-page":"5461","DOI":"10.18632\/oncotarget.6684","article-title":"Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma","volume":"7","author":"Yang","year":"2016","journal-title":"Oncotarget"},{"key":"key20200713224201_b44-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"2398","DOI":"10.3892\/or.2016.4999","article-title":"miR-124 inhibits proliferation and invasion of human retinoblastoma cells by targeting STAT3","volume":"36","author":"Liu","year":"2016","journal-title":"Oncol Rep"},{"key":"key20200713224201_b45-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1053\/j.gastro.2006.01.006","article-title":"Ubiquitous activation of Ras and Jak\/Stat pathways in human HCC","volume":"130","author":"Calvisi","year":"2006","journal-title":"Gastroenterology"},{"key":"key20200713224201_b46-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1093\/carcin\/bgw029","article-title":"Transcriptional activation of FN1 and IL11 by HMGA2 promotes the malignant behavior of colorectal cancer","volume":"37","author":"Wu","year":"2016","journal-title":"Carcinogenesis"},{"key":"key20200713224201_b47-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.ccr.2014.03.010","article-title":"A long noncoding RNA activated by TGF-\u03b2 promotes the invasion-metastasis cascade in hepatocellular carcinoma","volume":"25","author":"Yuan","year":"2014","journal-title":"Cancer Cell"},{"key":"key20200713224201_b48-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"435","DOI":"10.2174\/1568009615666150407124747","article-title":"Tumoural expression of connective tissue growth factor (CTGF) impacts on survival in patients diagnosed with hepatocellular carcinoma (HCC)","volume":"15","author":"Lamarca","year":"2015","journal-title":"Curr Cancer Drug Targets"},{"key":"key20200713224201_b49-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"40733","DOI":"10.1038\/srep40733","article-title":"miR-124 inhibits the migration and invasion of human hepatocellular carcinoma cells by suppressing integrin \u03b1V expression","volume":"7","author":"Cai","year":"2017","journal-title":"Sci Rep"},{"key":"key20200713224201_b50-mmr-17-03-3972","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1136\/gut.2011.239145","article-title":"The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2","volume":"61","author":"Zheng","year":"2012","journal-title":"Gut"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T22:51:11Z","timestamp":1594680671000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2017.8348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,27]]},"references-count":50,"URL":"https:\/\/doi.org\/10.3892\/mmr.2017.8348","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,27]]}}}