{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T11:23:45Z","timestamp":1722684225854},"reference-count":63,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Report"],"DOI":"10.3892\/mmr.2018.9590","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T10:53:35Z","timestamp":1540378415000},"source":"Crossref","is-referenced-by-count":4,"title":["Selenocysteine mimics the effect of dietary restriction on lifespan via SKN\u20111 and retards age\u2011associated pathophysiological changes in Caenorhabditis\ufffdelegans"],"prefix":"10.3892","author":[{"given":"So\u2011Hyeon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology, College of Medical Sciences, Soonchunhyang University, Asan, Chungnam 31538, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u2011Kyoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology, College of Medical Sciences, Soonchunhyang University, Asan, Chungnam 31538, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang\u2011Kyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology, College of Medical Sciences, Soonchunhyang University, Asan, Chungnam 31538, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"key20200713231242_b1-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1126\/science.45.1160.294","article-title":"The effect of retardation of growth upon the breeding period and duration of life of rats","volume":"45","author":"Osborne","year":"1917","journal-title":"Science"},{"key":"key20200713231242_b2-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1046\/j.1420-9101.1993.6020171.x","article-title":"Phenotypic plasticity and selection in Drosophila life history evolution. I. Nutrition and the cost of reproduction","volume":"6","author":"Chippindale","year":"1993","journal-title":"J Evol Biol"},{"key":"key20200713231242_b3-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0047-6374(94)90104-X","article-title":"Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse","volume":"74","author":"Sohal","year":"1994","journal-title":"Mech Ageing Dev"},{"key":"key20200713231242_b4-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1126\/science.1173635","article-title":"Caloric restriction delays disease onset and mortality in rhesus monkeys","volume":"325","author":"Colman","year":"2009","journal-title":"Science"},{"key":"key20200713231242_b5-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/0047-6374(77)90043-4","article-title":"Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span","volume":"6","author":"Klass","year":"1977","journal-title":"Mech Ageing Dev"},{"key":"key20200713231242_b6-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"13091","DOI":"10.1073\/pnas.95.22.13091","article-title":"The genetics of caloric restriction in Caenorhabditis elegans","volume":"95","author":"Lakowski","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713231242_b7-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"4129","DOI":"10.1242\/jeb.02492","article-title":"Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction","volume":"209","author":"Szewczyk","year":"2006","journal-title":"J Exp Biol"},{"key":"key20200713231242_b8-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1126\/science.1086016","article-title":"Demography of dietary restriction and death in Drosophila","volume":"301","author":"Mair","year":"2003","journal-title":"Science"},{"key":"key20200713231242_b9-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1038\/nature02789","article-title":"Sirtuin activators mimic caloric restriction and delay ageing in metazoans","volume":"430","author":"Wood","year":"2004","journal-title":"Nature"},{"key":"key20200713231242_b10-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"e2264","DOI":"10.1371\/journal.pone.0002264","article-title":"A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice","volume":"3","author":"Barger","year":"2008","journal-title":"PLoS One"},{"key":"key20200713231242_b11-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3389\/fnut.2016.00031","article-title":"Putative role of red wine polyphenols against brain pathology in Alzheimer's and Parkinson's disease","volume":"3","author":"Caruana","year":"2016","journal-title":"Front Nutr"},{"key":"key20200713231242_b12-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1158\/1535-7163.MCT-09-1186","article-title":"Metformin in cancer therapy: A new perspective for an old antidiabetic drug?","volume":"9","author":"Ben Sahra","year":"2010","journal-title":"Mol Cancer Ther"},{"key":"key20200713231242_b13-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"3179","DOI":"10.2174\/138161209789057995","article-title":"Oral antidiabetic agents: Anti-atherosclerotic properties beyond glucose lowering?","volume":"15","author":"Papanas","year":"2009","journal-title":"Curr Pharm Des"},{"key":"key20200713231242_b14-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/j.1440-1797.2010.01328.x","article-title":"Review: Metformin: Potential benefits and use in chronic kidney disease","volume":"15","author":"Pilmore","year":"2010","journal-title":"Nephrology (Carlton)"},{"key":"key20200713231242_b15-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1016\/j.cub.2007.08.047","article-title":"An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans","volume":"17","author":"Greer","year":"2007","journal-title":"Curr Biol"},{"key":"key20200713231242_b16-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"e8758","DOI":"10.1371\/journal.pone.0008758","article-title":"Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1","volume":"5","author":"Onken","year":"2010","journal-title":"PLoS One"},{"key":"key20200713231242_b17-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1152\/physiolgenomics.00069.2005","article-title":"Identification of potential caloric restriction mimetics by microarray profiling","volume":"23","author":"Dhahbi","year":"2005","journal-title":"Physiol Genomics"},{"key":"key20200713231242_b18-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1016\/j.bbrc.2017.09.147","article-title":"d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic","volume":"493","author":"Shintani","year":"2017","journal-title":"Biochem Biophys Res Commun"},{"key":"key20200713231242_b19-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"6976","DOI":"10.1073\/pnas.1319022111","article-title":"Redox active motifs in selenoproteins","volume":"111","author":"Li","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713231242_b20-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.mam.2005.07.004","article-title":"Selenium, oxidative stress, and health aspects","volume":"26","author":"Brenneisen","year":"2005","journal-title":"Mol Aspects Med"},{"key":"key20200713231242_b21-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/S0006-2952(00)00293-8","article-title":"Status of glutathione and other thiols and disulfides in human plasma","volume":"60","author":"Kleinman","year":"2000","journal-title":"Biochem Pharmacol"},{"key":"key20200713231242_b22-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/S0753-3322(03)00035-0","article-title":"The antioxidant role of selenium and seleno-compounds","volume":"57","author":"Tapiero","year":"2003","journal-title":"Biomed Pharmacother"},{"key":"key20200713231242_b23-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.3892\/mmr.2016.5464","article-title":"Protection of rat liver against hepatic ischemia-reperfusion injury by a novel selenocysteine-containing 7-mer peptide","volume":"14","author":"Jiang","year":"2016","journal-title":"Mol Med Rep"},{"key":"key20200713231242_b24-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"2852","DOI":"10.1007\/s12035-016-9835-0","article-title":"The protective role of selenium on scopolamine-induced memory impairment, oxidative stress, and apoptosis in aged rats: The involvement of TRPM2 and TRPV1 channels","volume":"54","author":"Balaban","year":"2017","journal-title":"Mol Neurobiol"},{"key":"key20200713231242_b25-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"32563","DOI":"10.1038\/srep32563","article-title":"Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase","volume":"6","author":"Puppala","year":"2016","journal-title":"Sci Rep"},{"key":"key20200713231242_b26-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.fct.2013.11.030","article-title":"Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16\/FOXO pathway","volume":"64","author":"Wollenhaupt","year":"2014","journal-title":"Food Chem Toxicol"},{"key":"key20200713231242_b27-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1073\/pnas.1006328108","article-title":"Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans","volume":"108","author":"Stenvall","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713231242_b28-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"491","DOI":"10.6061\/clinics\/2017(08)07","article-title":"Selenocysteine modulates resistance to environmental stress and confers anti-aging effects in C. elegans","volume":"72","author":"Kim","year":"2017","journal-title":"Clinics (Sao Paulo)"},{"key":"key20200713231242_b29-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1038\/nature01278","article-title":"Systematic functional analysis of the Caenorhabditis elegans genome using RNAi","volume":"421","author":"Kamath","year":"2003","journal-title":"Nature"},{"key":"key20200713231242_b30-mmr-18-06-5389","first-page":"pp185","article-title":"Asymptotically efficient rank invariant test procedures","volume":"135","author":"Peto","year":"1972","journal-title":"JSTOR"},{"key":"key20200713231242_b31-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1126\/science.2392681","article-title":"Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging","volume":"249","author":"Johnson","year":"1990","journal-title":"Science"},{"key":"key20200713231242_b32-mmr-18-06-5389","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1093\/genetics\/139.3.1247","article-title":"Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing","volume":"139","author":"Wong","year":"1995","journal-title":"Genetics"},{"key":"key20200713231242_b33-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1038\/nature05904","article-title":"Two neurons mediate diet-restriction-induced longevity in C. elegans","volume":"447","author":"Bishop","year":"2007","journal-title":"Nature"},{"key":"key20200713231242_b34-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.cell.2013.11.046","article-title":"De novo inference of systems-level mechanistic models of development from live-imaging-based phenotype analysis","volume":"156","author":"Du","year":"2014","journal-title":"Cell"},{"key":"key20200713231242_b35-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1111\/j.1474-9726.2009.00473.x","article-title":"Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1","volume":"8","author":"Park","year":"2009","journal-title":"Aging Cell"},{"key":"key20200713231242_b36-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s00775-010-0723-1","article-title":"Sodium sulfite is a potential hypoxia inducer that mimics hypoxic stress in Caenorhabditis elegans","volume":"16","author":"Jiang","year":"2011","journal-title":"J Biol Inorg Chem"},{"key":"key20200713231242_b37-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.ydbio.2005.07.010","article-title":"Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18","volume":"286","author":"Masse","year":"2005","journal-title":"Dev Biol"},{"key":"key20200713231242_b38-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1016\/j.exger.2003.10.017","article-title":"The retardation of aging by caloric restriction: Its significance in the transgenic era","volume":"38","author":"Barger","year":"2003","journal-title":"Exp Gerontol"},{"key":"key20200713231242_b39-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/nrn2474","article-title":"The insulin paradox: Aging, proteotoxicity and neurodegeneration","volume":"9","author":"Cohen","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"key20200713231242_b40-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1975","DOI":"10.1016\/S0960-9822(01)00594-2","article-title":"daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans","volume":"11","author":"Henderson","year":"2001","journal-title":"Curr Biol"},{"key":"key20200713231242_b41-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.exger.2016.10.011","article-title":"Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans","volume":"87","author":"Ihara","year":"2017","journal-title":"Exp Gerontol"},{"key":"key20200713231242_b42-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.metabol.2018.01.012","article-title":"Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice","volume":"83","author":"Mayurasakorn","year":"2018","journal-title":"Metabolism"},{"key":"key20200713231242_b43-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"e78788","DOI":"10.1371\/journal.pone.0078788","article-title":"Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans","volume":"8","author":"Schlernitzauer","year":"2013","journal-title":"PLoS One"},{"key":"key20200713231242_b44-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.mad.2016.11.001","article-title":"Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Japan: Part 1-centenarians in Okinawa","volume":"165","author":"Willcox","year":"2017","journal-title":"Mech Ageing Dev"},{"key":"key20200713231242_b45-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1096\/fj.09-142984","article-title":"Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans","volume":"24","author":"Park","year":"2010","journal-title":"FASEB J"},{"key":"key20200713231242_b46-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/j.1474-9726.2009.00459.x","article-title":"Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans","volume":"8","author":"Greer","year":"2009","journal-title":"Aging Cell"},{"key":"key20200713231242_b47-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1038\/nature07583","article-title":"Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans","volume":"457","author":"Honjoh","year":"2009","journal-title":"Nature"},{"key":"key20200713231242_b48-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.mad.2010.02.007","article-title":"Resveratrol, sirtuins, and the promise of a DR mimetic","volume":"131","author":"Baur","year":"2010","journal-title":"Mech Ageing Dev"},{"key":"key20200713231242_b49-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1038\/nature01960","article-title":"Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan","volume":"425","author":"Howitz","year":"2003","journal-title":"Nature"},{"key":"key20200713231242_b50-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.cell.2013.06.016","article-title":"The NAD(+)\/Sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling","volume":"154","author":"Mouchiroud","year":"2013","journal-title":"Cell"},{"key":"key20200713231242_b51-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"683","DOI":"10.4161\/cc.9.4.10766","article-title":"Calorie restriction: Decelerating mTOR-driven aging from cells to organisms (including humans)","volume":"9","author":"Blagosklonny","year":"2010","journal-title":"Cell Cycle"},{"key":"key20200713231242_b52-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1111\/acel.12109","article-title":"Late-life rapamycin treatment reverses age-related heart dysfunction","volume":"12","author":"Flynn","year":"2013","journal-title":"Aging Cell"},{"key":"key20200713231242_b53-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.neuroscience.2012.06.054","article-title":"Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice","volume":"223","author":"Halloran","year":"2012","journal-title":"Neuroscience"},{"key":"key20200713231242_b54-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1126\/science.1081447","article-title":"The endocrine regulation of aging by insulin-like signals","volume":"299","author":"Tatar","year":"2003","journal-title":"Science"},{"key":"key20200713231242_b55-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s10068-017-0079-1","article-title":"N-acetyl-l-cysteine mimics the effect of dietary restriction on lifespan and reduces amyloid beta-induced toxicity in Caenorhabditis elegans","volume":"26","author":"Oh","year":"2017","journal-title":"Food Sci Biotechnol"},{"key":"key20200713231242_b56-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"411","DOI":"10.14393\/BJ-v33n2-32846","article-title":"Supplementation of S-ALLYL cysteine improves health span in Caenorhabditis elegans","volume":"33","author":"Kim","year":"2017","journal-title":"Biosci J"},{"key":"key20200713231242_b57-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.nbd.2006.12.019","article-title":"Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease","volume":"26","author":"Halagappa","year":"2007","journal-title":"Neurobiol Dis"},{"key":"key20200713231242_b58-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1093\/gerona\/gls219","article-title":"Calorie restriction does not increase short-term or long-term protein synthesis","volume":"68","author":"Miller","year":"2013","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"key20200713231242_b59-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"4239","DOI":"10.1073\/pnas.79.13.4239","article-title":"Action of food restriction in delaying the aging process","volume":"79","author":"Masoro","year":"1982","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200713231242_b60-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1096\/fj.03-0667fje","article-title":"Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle","volume":"18","author":"McKiernan","year":"2004","journal-title":"FASEB J"},{"key":"key20200713231242_b61-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1017\/S0029665113003832","article-title":"Dietary restriction and the pursuit of effective mimetics","volume":"73","author":"Selman","year":"2014","journal-title":"Proc Nutr Soc"},{"key":"key20200713231242_b62-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"e1001204","DOI":"10.1371\/journal.pmed.1001204","article-title":"Reappraisal of metformin efficacy in the treatment of type 2 diabetes: A meta-analysis of randomised controlled trials","volume":"9","author":"Boussageon","year":"2012","journal-title":"PLoS Med"},{"key":"key20200713231242_b63-mmr-18-06-5389","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.mad.2007.07.007","article-title":"Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans","volume":"128","author":"Bass","year":"2007","journal-title":"Mech Ageing Dev"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2022,9,4]],"date-time":"2022-09-04T15:06:51Z","timestamp":1662304011000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2018.9590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":63,"URL":"https:\/\/doi.org\/10.3892\/mmr.2018.9590","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,24]]}}}