{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:49:07Z","timestamp":1790610547951,"version":"4.1.0"},"reference-count":40,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Report"],"DOI":"10.3892\/mmr.2019.10236","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T07:21:02Z","timestamp":1557818462000},"source":"Crossref","is-referenced-by-count":5,"title":["Identification of pathogenic genes and transcription factors in glaucoma"],"prefix":"10.3892","author":[{"given":"Jie","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, The First People's Hospital of Jining, Jining, Shandong 272011, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The First People's Hospital of Jining, Jining, Shandong 272011, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2019,5,14]]},"reference":[{"key":"key20200713232928_b1-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"key20200713232928_b2-mmr-20-01-0216","first-page":"1891","article-title":"Alterations in the aqueous humor proteome in patients with a glaucoma shunt device","volume":"17","author":"Anshu","year":"2011","journal-title":"Mol Vis"},{"key":"key20200713232928_b3-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.arr.2016.05.012","article-title":"From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma","volume":"29","author":"Sacc\u00e0","year":"2016","journal-title":"Ageing Res Rev"},{"key":"key20200713232928_b4-mmr-20-01-0216","first-page":"60","article-title":"Presentation of primary open angle glaucoma (POAG) at lions sight first eye hospital in Blantyre, Malawi","volume":"26","author":"Kayange","year":"2014","journal-title":"Malawi Med J"},{"key":"key20200713232928_b5-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1056\/NEJMra0804630","article-title":"Primary open-angle glaucoma","volume":"2","author":"Kwon","year":"2009","journal-title":"N Engl J Med"},{"key":"key20200713232928_b6-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"e0195157","DOI":"10.1371\/journal.pone.0195157","article-title":"A novel single nucleotide polymorphism in exon 3 of MYOC enhances the risk of glaucoma","volume":"13","author":"Nazir","year":"2018","journal-title":"PLoS One"},{"key":"key20200713232928_b7-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"4498","DOI":"10.1038\/s41598-018-22337-2","article-title":"Detection of mutations in MYOC, OPTN, NTF4, WDR36 and CYP1B1 in Chinese juvenile onset open-angle glaucoma using exome sequencing","volume":"8","author":"Huang","year":"2018","journal-title":"Sci Rep"},{"key":"key20200713232928_b8-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"2482","DOI":"10.1093\/hmg\/ddr123","article-title":"Copy number variations on chromosome 12q14 in patients with normal tension glaucoma","volume":"20","author":"Fingert","year":"2011","journal-title":"Hum Mol Genet"},{"key":"key20200713232928_b9-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.exer.2011.12.021","article-title":"Confirmation of TBK1 duplication in normal tension glaucoma","volume":"96","author":"Kawase","year":"2012","journal-title":"Exp Eye Res"},{"key":"key20200713232928_b10-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1001\/jamaophthalmol.2014.104","article-title":"TBK1 gene duplication and normal-tension glaucoma","volume":"132","author":"Ritch","year":"2014","journal-title":"JAMA Ophthalmol"},{"key":"key20200713232928_b11-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1038\/ng.824","article-title":"Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1","volume":"43","author":"Burdon","year":"2011","journal-title":"Nat Genet"},{"key":"key20200713232928_b12-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"28736","DOI":"10.1038\/srep28736","article-title":"Transcriptome profiling of the rat retina after optic nerve transection","volume":"6","author":"Yasuda","year":"2016","journal-title":"Sci Rep"},{"key":"key20200713232928_b13-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"29156","DOI":"10.1074\/jbc.M802365200","article-title":"Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma","volume":"283","author":"Shi","year":"2008","journal-title":"J Biol Chem"},{"key":"key20200713232928_b14-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1038\/eye.2000.197","article-title":"Compliance and viewpoint of glaucoma patients in greece","volume":"14","author":"Konstas","year":"2000","journal-title":"Eye (Lond)"},{"key":"key20200713232928_b15-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1128\/JCM.01247-08","article-title":"Development of a rapid high-throughput method for high-resolution melting analysis for routine detection and genotyping of noroviruses","volume":"47","author":"Tajiri-Utagawa","year":"2009","journal-title":"J Clin Microbiol"},{"key":"key20200713232928_b16-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"2721","DOI":"10.12659\/MSM.905064","article-title":"Genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease","volume":"23","author":"Chang","year":"2017","journal-title":"Med Sci Monit"},{"key":"key20200713232928_b17-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"6382","DOI":"10.1167\/iovs.13-12128","article-title":"Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma","volume":"54","author":"Liu","year":"2013","journal-title":"Invest Ophthalmol Vis Sci Sep"},{"key":"key20200713232928_b18-mmr-20-01-0216","first-page":"774","article-title":"Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue","volume":"12","author":"Liton","year":"2006","journal-title":"Mol Vis"},{"key":"key20200713232928_b19-mmr-20-01-0216","first-page":"D991","article-title":"NCBI GEO: Archive for functional genomics data sets-update","author":"Barrett","year":"2013","journal-title":"Nucleic Acids Rese 41 (Database Issue)"},{"key":"key20200713232928_b20-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1302\/2046-3758.512.BJR-2016-0073.R1","article-title":"Identification of candidate genes in osteoporosis by integrated microarray analysis","volume":"5","author":"Li","year":"2016","journal-title":"Bone Joint Res"},{"key":"key20200713232928_b21-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"key20200713232928_b22-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/0306-9877(95)90228-7","article-title":"Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus","volume":"45","author":"Klipper-Aurbach","year":"1995","journal-title":"Med Hypotheses"},{"key":"key20200713232928_b23-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: Tool for the unification of biology. The gene ontology consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat Genet"},{"key":"key20200713232928_b24-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key20200713232928_b25-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s13000-016-0596-x","article-title":"A transcriptome profile in hepatocellular carcinomas based on integrated analysis of microarray studies","volume":"12","author":"Wang","year":"2017","journal-title":"Diagn Pathol"},{"key":"key20200713232928_b26-mmr-20-01-0216","first-page":"133","article-title":"From congenital glaucoma to chronic open angle glaucoma in adulthood: A clinical and genetic continuum","volume":"197","author":"Dufier","year":"2013","journal-title":"Bull Acad Natl Med"},{"key":"key20200713232928_b27-mmr-20-01-0216","first-page":"1201","article-title":"Mutual regulation of the Hippo\/Wnt\/LPA\/TGF-\u03b2 signaling pathways and their roles in glaucoma (review)","volume":"41","author":"Wang","year":"2018","journal-title":"Int J Mol Med"},{"key":"key20200713232928_b28-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00428-009-0825-8","article-title":"Neutrophil gelatinase-associated lipocalin (NGAL\/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori","volume":"455","author":"Alp\u00edzar-Alp\u00edzar","year":"2009","journal-title":"Virchows Archiv"},{"key":"key20200713232928_b29-mmr-20-01-0216","first-page":"293","article-title":"Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line","volume":"13","author":"Khalyfa","year":"2007","journal-title":"Mol Vis"},{"key":"key20200713232928_b30-mmr-20-01-0216","first-page":"211","article-title":"Ocular hypotensive effects of monoamine oxidase-a inhibitors in rabbit","volume":"32","author":"Maeda","year":"1988","journal-title":"Jpn J Ophthalmol"},{"key":"key20200713232928_b31-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1046\/j.1471-4159.2003.01562.x","article-title":"Effects of phosphatidylserine on p38 mitogen activated protein kinase, cyclic AMP responding element binding protein and nuclear factor-kappaB activation in resting and activated microglial cells","volume":"84","author":"Ajmone-Cat","year":"2003","journal-title":"J Neurochem"},{"key":"key20200713232928_b32-mmr-20-01-0216","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1046\/j.1471-4159.1999.01836.x","article-title":"CREB phosphorylation promotes nerve cell survival","volume":"73","author":"Walton","year":"1999","journal-title":"J Neurochem"},{"key":"key20200713232928_b33-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s12031-015-0522-9","article-title":"Inhibition of miR-134 protects against hydrogen peroxide-induced apoptosis in retinal ganglion cells","volume":"56","author":"Shao","year":"2015","journal-title":"J Mol Neurosci"},{"key":"key20200713232928_b34-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"3861","DOI":"10.1242\/jcs.00059","article-title":"Fibronectin at a glance","volume":"115","author":"Pankov","year":"2002","journal-title":"J Cell Sci"},{"key":"key20200713232928_b35-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"3145","DOI":"10.3892\/or.2016.5177","article-title":"High expression of fibronectin is associated with poor prognosis, cell proliferation and malignancy via the NF-\u03baB\/p53-apoptosis signaling pathway in colorectal cancer","volume":"36","author":"Yi","year":"2016","journal-title":"Oncol Rep"},{"key":"key20200713232928_b36-mmr-20-01-0216","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12695","article-title":"Inflammasome activators induce fibronectin expression and release in macrophages","volume":"19","author":"Jun","year":"2017","journal-title":"Cell Microbiol"},{"key":"key20200713232928_b37-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1111\/j.1471-4159.2008.05505.x","article-title":"NELL2 participates in formation of the sexually dimorphic nucleus of the pre-optic area in rats","volume":"106","author":"Jeong","year":"2008","journal-title":"J Neurochem"},{"key":"key20200713232928_b38-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1126\/science.7892602","article-title":"Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila","volume":"267","author":"Halder","year":"1995","journal-title":"Science"},{"key":"key20200713232928_b39-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1093\/hmg\/9.6.917","article-title":"Vertebrate eye development as modeled in Drosophila","volume":"9","author":"Wawersik","year":"2000","journal-title":"Hum Mol Genet"},{"key":"key20200713232928_b40-mmr-20-01-0216","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s00427-015-0493-4","article-title":"Genetic interaction between Pax6 and \u03b2-catenin in the developing retinal pigment epithelium","volume":"225","author":"Fujimura","year":"2015","journal-title":"Dev Genes Evol"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:27:34Z","timestamp":1721262454000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2019.10236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,14]]},"references-count":40,"URL":"https:\/\/doi.org\/10.3892\/mmr.2019.10236","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,14]]}}}