{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T05:07:59Z","timestamp":1649135279658},"reference-count":66,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Rep"],"DOI":"10.3892\/mmr.2020.11476","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T08:22:47Z","timestamp":1599034967000},"source":"Crossref","is-referenced-by-count":1,"title":["Analysis of biomarkers and metabolic pathways in patients with unstable angina based on ultra\u2011high\u2011performance liquid chromatography\u2011quadrupole time\u2011of\u2011flight mass spectrometry"],"prefix":"10.3892","author":[{"given":"Yuechen","family":"Liu","sequence":"first","affiliation":[{"name":"College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Li","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianpu","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simiao","family":"Fan","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemeng","family":"Cai","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijia","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhu","family":"Li","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Gao","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yubo","family":"Li","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunquan","family":"Yu","sequence":"additional","affiliation":[{"name":"Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2020,9,2]]},"reference":[{"key":"key20201006121202_b1-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"e67","DOI":"10.1161\/CIR.0000000000000558","article-title":"Heart disease and stroke statistics-2018 update: A report from the American heart association","volume":"137","author":"Benjamin","year":"2018","journal-title":"Circulation"},{"key":"key20201006121202_b2-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/j.amjmed.2015.01.044","article-title":"Diagnosis of unstable angina pectoris has declined markedly with the advent of more sensitive troponin assays","volume":"128","author":"D'Souza","year":"2015","journal-title":"Am J Med"},{"key":"key20201006121202_b3-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1093\/eurheartj\/ehu178","article-title":"Early discharge using single cardiac troponin and copeptin testing in patients with suspected acute coronary syndrome (ACS): A randomized, controlled clinical process study","volume":"36","author":"M\u00f6ckel","year":"2015","journal-title":"Eur Heart J"},{"key":"key20201006121202_b4-mmr-22-05-3862","article-title":"Unstable Angina","author":"Amandeep","year":"2020"},{"key":"key20201006121202_b5-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1056\/NEJM200001133420207","article-title":"Unstable angina pectoris","volume":"342","author":"Yeghiazarians","year":"2000","journal-title":"New Engl J Med"},{"key":"key20201006121202_b6-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1039\/c3mb70216b","article-title":"Identification of biomarkers for unstable angina by plasma metabolomic profiling","volume":"9","author":"Sun","year":"2013","journal-title":"Mol Biosyst"},{"key":"key20201006121202_b7-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"2563","DOI":"10.1161\/CIRCULATIONAHA.107.737312","article-title":"Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation","volume":"116","author":"Anderson","year":"2007","journal-title":"Circulation"},{"key":"key20201006121202_b8-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1152\/physrev.00035.2018","article-title":"Metabolomics for investigating physiological and pathophysiological processes","volume":"99","author":"David","year":"2019","journal-title":"Physiol Rev"},{"key":"key20201006121202_b9-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1080\/14737159.2019.1656530","article-title":"The applications of metabolomics in the molecular diagnostics of cancer","volume":"19","author":"Cheung","year":"2019","journal-title":"Expert Rev Mol Diagn"},{"key":"key20201006121202_b10-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1039\/b902356a","article-title":"Systems biology approaches and pathway tools for investigating cardiovascular disease","volume":"5","author":"Wheelock","year":"2009","journal-title":"Mol Biosyst"},{"key":"key20201006121202_b11-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/nrm3314","article-title":"Innovation: Metabolomics: The apogee of the omics trilogy","volume":"13","author":"Patti","year":"2012","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20201006121202_b12-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3390\/metabo10020051","article-title":"Toward a standardized srategy of clinical metabolomics for the advancement of precision medicine","volume":"10","author":"Long","year":"2020","journal-title":"Metabolites"},{"key":"key20201006121202_b13-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1038\/4551054a","article-title":"Systems biology: Metabonomics","volume":"455","author":"Nicholson","year":"2008","journal-title":"Nature"},{"key":"key20201006121202_b14-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1097\/COH.0b013e32833ed177","article-title":"What are biomarkers?","volume":"5","author":"Strimbu","year":"2010","journal-title":"Curr Opin HIV AIDS"},{"key":"key20201006121202_b15-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.jpba.2014.12.017","article-title":"Metabolomics for laboratory diagnostics","volume":"113","author":"Bujak","year":"2015","journal-title":"J Pharm Biomed Anal"},{"key":"key20201006121202_b16-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.jprot.2014.01.014","article-title":"Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease","volume":"104","author":"Gonz\u00e1lez-Dom\u00ednguez","year":"2014","journal-title":"J Proteomics"},{"key":"key20201006121202_b17-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"e16957","DOI":"10.1371\/journal.pone.0016957","article-title":"The human serum metabolome","volume":"6","author":"Psychogios","year":"2011","journal-title":"PLoS One"},{"key":"key20201006121202_b18-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"e73076","DOI":"10.1371\/journal.pone.0073076","article-title":"The human urine metabolome","volume":"8","author":"Bouatra","year":"2013","journal-title":"PLoS One"},{"key":"key20201006121202_b19-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"e0122950","DOI":"10.1371\/journal.pone.0122950","article-title":"Two Urinary Peptides Associated Closely With Type 2 Diabetes Mellitus","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"key":"key20201006121202_b20-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.talanta.2016.06.032","article-title":"Pre-analytical and analytical validations and clinical applications of a miniaturized, simple and cost-effective solid phase extraction combined with LC-MS\/MS for the simultaneous determination of catecholamines and metanephrines in spot urine samples","volume":"159","author":"Li","year":"2016","journal-title":"Talanta"},{"key":"key20201006121202_b21-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.jchromb.2018.10.005","article-title":"Urinary metabonomic study of patients with acute coronary syndrome using UPLC-QTOF\/MS","volume":"1100","author":"Wang","year":"2018","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"key20201006121202_b22-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jchromb.2015.07.045","article-title":"A metabolomics strategy to explore urinary biomarkers and metabolic pathways for assessment of interaction between Danhong injection and low-dose aspirin during their synergistic treatment","volume":"1026","author":"Li","year":"2016","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"key20201006121202_b23-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.clinbiochem.2010.11.010","article-title":"\u00b9H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure","volume":"44","author":"Kang","year":"2011","journal-title":"Clin Biochem"},{"key":"key20201006121202_b24-mmr-22-05-3862","first-page":"25","article-title":"Guidelines for the diagnosis and treatment of unstable angina and non-ST-segment elevation myocardial infarction","volume":"35","author":"Chinese Medical Association Cardiovascular Branch, Editorial Board of the Chinese Journal of Cardiovascular Diseases","year":"2007","journal-title":"Chin J Cardiol"},{"key":"key20201006121202_b25-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.chroma.2014.08.028","article-title":"Metabonomic study of chronic heart failure and effects of Chinese herbal decoction in rats","volume":"1362","author":"Guo","year":"2014","journal-title":"J Chromatogr A"},{"key":"key20201006121202_b26-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s11306-010-0262-3","article-title":"Metabolic profiling of HepG2 cells incubated with S(\u2212) and R(+) enantiomers of anti-coagulating drug warfarin","volume":"7","author":"Bai","year":"2011","journal-title":"Metabolomics"},{"key":"key20201006121202_b27-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"22525","DOI":"10.1038\/srep22525","article-title":"Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease","volume":"6","author":"Feng","year":"2016","journal-title":"Sci Rep"},{"key":"key20201006121202_b28-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1152\/physrev.2000.80.3.1107","article-title":"Creatine and creatinine metabolism","volume":"80","author":"Wyss","year":"2000","journal-title":"Physiol Rev"},{"key":"key20201006121202_b29-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.1021\/pr2010082","article-title":"Plasma metabonomics as a novel diagnostic approach for major depressive disorder","volume":"11","author":"Zheng","year":"2012","journal-title":"J Proteome Res"},{"key":"key20201006121202_b30-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.jgr.2019.02.005","article-title":"Protein target identification of ginsenosides in skeletal muscle tissues: Discovery of natural small-molecule activators of muscle-type creatine kinase","volume":"44","author":"Chen","year":"2020","journal-title":"J Ginseng Res"},{"key":"key20201006121202_b31-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1097\/WNP.0000000000000568","article-title":"Repeated transcranial magnetic stimulation-induced motor evoked potentials correlate with the subject-specific serum metabolic profile of creatine","volume":"36","author":"Kallioniemi","year":"2019","journal-title":"J Clin Neurophysiol"},{"key":"key20201006121202_b32-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/1471-2393-14-150","article-title":"Creatine supplementation during pregnancy: Summary of experimental studies suggesting a treatment to improve fetal and neonatal morbidity and reduce mortality in high-risk human pregnancy","volume":"14","author":"Dickinson","year":"2014","journal-title":"BMC Pregnancy Childbirth"},{"key":"key20201006121202_b33-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"3387","DOI":"10.1039\/C5MB00489F","article-title":"Analysis of urinary metabolomic profiling for unstable angina pectoris disease based on nuclear magnetic resonance spectroscopy","volume":"11","author":"Li","year":"2015","journal-title":"Mol Biosyst"},{"key":"key20201006121202_b34-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.atherosclerosis.2014.08.040","article-title":"Creatinine, eGFR and association with myocardial infarction, ischemic heart disease and early death in the general population","volume":"237","author":"Sibilitz","year":"2014","journal-title":"Atherosclerosis"},{"key":"key20201006121202_b35-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.ijcard.2016.09.089","article-title":"Patients with calcific aortic stenosis exhibit systemic molecular evidence of ischemia, enhanced coagulation, oxidative stress and impaired cholesterol transport","volume":"225","author":"Mourino-Alvarez","year":"2016","journal-title":"Int J Cardiol"},{"key":"key20201006121202_b36-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.vph.2015.11.001","article-title":"Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium","volume":"79","author":"Sharma","year":"2016","journal-title":"Vascul Pharmacol"},{"key":"key20201006121202_b37-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1016\/j.atherosclerosis.2007.05.012","article-title":"Anti-oxidant and anti-atherogenic properties of liposomal glutathione: Studies in vitro, and in the atherosclerotic apolipoprotein E-deficient mice","volume":"195","author":"Rosenblat","year":"2007","journal-title":"Atherosclerosis"},{"key":"key20201006121202_b38-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1161\/ATVBAHA.107.142109","article-title":"Increased expression of glutathione reductase in macrophages decreases atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice","volume":"27","author":"Qiao","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key20201006121202_b39-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"},{"key":"key20201006121202_b40-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1161\/ATVBAHA.113.302131","article-title":"G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery","volume":"34","author":"Hamel","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key20201006121202_b41-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1161\/CIRCULATIONAHA.117.031139","article-title":"Functional metabolomics characterizes a key role for n-acetylneuraminic acid in coronary artery diseases","volume":"137","author":"Zhang","year":"2018","journal-title":"Circulation"},{"key":"key20201006121202_b42-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.amjcard.2014.06.012","article-title":"Plasma-free fatty acids, fatty acid-binding protein 4, and mortality in older adults (from the Cardiovascular Health Study)","volume":"114","author":"Miedema","year":"2014","journal-title":"Am J Cardiol"},{"key":"key20201006121202_b43-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1111\/j.1365-2125.2012.04177.x","article-title":"Use of dicarboxylic acids in type 2 diabetes","volume":"75","author":"Mingrone","year":"2013","journal-title":"Br J Clin Pharmacol"},{"key":"key20201006121202_b44-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1039\/C5AN01970B","article-title":"The anti-atherosclerotic effect of tanshinol borneol ester using fecal metabolomics based on liquid chromatography-mass spectrometry","volume":"141","author":"Jia","year":"2016","journal-title":"Analyst"},{"key":"key20201006121202_b45-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/S0190-9622(87)70294-1","article-title":"Azelaic acid","volume":"17","author":"Nazzaro-Porro","year":"1987","journal-title":"J Am Acad Dermatol"},{"key":"key20201006121202_b46-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1039\/C4MB00682H","article-title":"A urinary metabolomics study of rats after the exposure to acrylamide by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry","volume":"11","author":"Wang","year":"2015","journal-title":"Mol Biosyst"},{"key":"key20201006121202_b47-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"519","DOI":"10.21873\/anticanres.13143","article-title":"Metabolomics-based discovery of serum biomarkers to predict the side-effects of neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma","volume":"39","author":"Nishiumi","year":"2019","journal-title":"Anticancer Res"},{"key":"key20201006121202_b48-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.3389\/fphar.2019.01244","article-title":"Measurement of thromboxane biosynthesis in health and disease","volume":"10","author":"Patrono","year":"2019","journal-title":"Front Pharmacol"},{"key":"key20201006121202_b49-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1186\/1752-153X-6-152","article-title":"New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity","volume":"6","author":"Hirz","year":"2012","journal-title":"Chem Cent J"},{"key":"key20201006121202_b50-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.atherosclerosis.2012.12.035","article-title":"Adipose tissue arachidonic acid content is associated with the risk of myocardial infarction: A Danish case-cohort study","volume":"227","author":"Nielsen","year":"2013","journal-title":"Atherosclerosis"},{"key":"key20201006121202_b51-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"209","DOI":"10.2217\/clp.10.11","article-title":"Thromboxane and the thromboxane receptor in cardiovascular disease","volume":"5","author":"Smyth","year":"2010","journal-title":"Clin Lipidol"},{"key":"key20201006121202_b52-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/0306-9877(84)90021-5","article-title":"The combined role of atheroma, cholesterol, platelets, the endothelium and fibrin in heart attacks and strokes","volume":"15","author":"Martin","year":"1984","journal-title":"Med Hypotheses"},{"key":"key20201006121202_b53-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.plefa.2013.06.008","article-title":"Identification of cytochrome P450s involved in the metabolism of arachidonic acid in human platelets","volume":"89","author":"Jarrar","year":"2013","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"key20201006121202_b54-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.cca.2016.02.020","article-title":"1H NMR-derived metabolomics of filtered serum of myocardial ischemia in unstable angina patients","volume":"456","author":"Ameta","year":"2016","journal-title":"Clin Chim Acta"},{"key":"key20201006121202_b55-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s11306-014-0718-y","article-title":"Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction","volume":"11","author":"Boyle","year":"2015","journal-title":"Metabolomics"},{"key":"key20201006121202_b56-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1161\/01.HYP.0000254480.64564.b6","article-title":"Hyperuricemia and incidence of hypertension among men without metabolic syndrome","volume":"49","author":"Krishnan","year":"2007","journal-title":"Hypertension"},{"key":"key20201006121202_b57-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/j.amjmed.2005.03.043","article-title":"Serum uric acid and cardiovascular disease: Recent developments, and where do they leave us?","volume":"118","author":"Baker","year":"2005","journal-title":"Am J Med"},{"key":"key20201006121202_b58-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cca.2008.02.024","article-title":"The paradoxical relationship between serum uric acid and cardiovascular disease","volume":"392","author":"Lippi","year":"2008","journal-title":"Clin Chim Acta"},{"key":"key20201006121202_b59-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"2742","DOI":"10.1161\/01.CIR.91.11.2742","article-title":"Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses","volume":"91","author":"Ajayi","year":"1995","journal-title":"Circulation"},{"key":"key20201006121202_b60-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"902","DOI":"10.18632\/aging.101438","article-title":"Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women","volume":"10","author":"Karolczak","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"key20201006121202_b61-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s10157-013-0840-6","article-title":"Low serum testosterone is associated with atherosclerosis in postmenopausal women undergoing hemodialysis","volume":"18","author":"Shiraki","year":"2014","journal-title":"Clin Exp Nephrol"},{"key":"key20201006121202_b62-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1097\/MED.0000000000000057","article-title":"Testosterone, aging and survival: Biomarker or deficiency","volume":"21","author":"Shores","year":"2014","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"key20201006121202_b63-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1111\/cen.13905","article-title":"Higher circulating androgens and higher physical activity levels are associated with less central adiposity and lower risk of cardiovascular death in older men","volume":"90","author":"Chasland","year":"2019","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key20201006121202_b64-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1002\/clc.22965","article-title":"Serum androgens and risk of atrial fibrillation in older men: The cardiovascular health study","volume":"41","author":"Rosenberg","year":"2018","journal-title":"Clin Cardiol"},{"key":"key20201006121202_b65-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1212\/WNL.0000000000004074","article-title":"Letter re: Long-term cortisol measures predict Alzheimer disease risk","volume":"89","author":"Lattanzi","year":"2017","journal-title":"Neurology"},{"key":"key20201006121202_b66-mmr-22-05-3862","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/ana.20432","article-title":"Acute intermittent porphyria presenting as a diffuse encephalopathy","volume":"57","author":"Maramattom","year":"2005","journal-title":"Ann Neurol"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T09:12:10Z","timestamp":1601975530000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2020.11476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,2]]},"references-count":66,"URL":"https:\/\/doi.org\/10.3892\/mmr.2020.11476","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,2]]}}}