{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:12:46Z","timestamp":1789456366529,"version":"build-2803163510"},"reference-count":71,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Rep"],"DOI":"10.3892\/mmr.2026.13970","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T11:47:39Z","timestamp":1784807259000},"page":"1-23","source":"Crossref","is-referenced-by-count":0,"title":["UBE2A as a prognostic indicator across human cancers: Insights from multi\u2011omics and immune landscape analyses"],"prefix":"10.3892","volume":"34","author":[{"given":"Yun","family":"Wen","sequence":"first","affiliation":[{"name":"Department of Breast and Thyroid Surgery, The Central Hospital of Yongzhou, Yongzhou, Hunan 425000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Oncology, The Central Hospital of Yongzhou, Yongzhou, Hunan 425000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"key20260915094341_b1-mmr-34-4-13970","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"key20260915094341_b2-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e2443198","DOI":"10.1001\/jamanetworkopen.2024.43198","article-title":"Global disparities of cancer and its projected burden in 2050","volume":"7","author":"Bizuayehu","year":"2024","journal-title":"JAMA Netw Open"},{"key":"key20260915094341_b3-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e20242282","DOI":"10.1084\/jem.20242282","article-title":"Tumor cell heterogeneity drives spatial organization of the intratumoral immune response","volume":"222","author":"Tanaka","year":"2025","journal-title":"J Exp Med"},{"key":"key20260915094341_b4-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"441","DOI":"10.3390\/cancers17030441","article-title":"Heterogeneity in cancer","volume":"17","author":"MacDonald","year":"2025","journal-title":"Cancers"},{"key":"key20260915094341_b5-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"217616","DOI":"10.1016\/j.canlet.2025.217616","article-title":"Clinical development of immuno-oncology therapeutics","volume":"617","author":"Wang","year":"2025","journal-title":"Cancer Lett"},{"key":"key20260915094341_b6-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/s12943-025-02305-x","article-title":"Advances in cancer immunotherapy: Historical perspectives, current developments, and future directions","volume":"24","author":"Zhang","year":"2025","journal-title":"Mol Cancer"},{"key":"key20260915094341_b7-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.stem.2024.06.003","article-title":"Cancer stem cell mimicry for immune evasion and therapeutic resistance","volume":"31","author":"Saw","year":"2024","journal-title":"Cell Stem Cell"},{"key":"key20260915094341_b8-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1038\/s41588-022-01141-9","article-title":"Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment","volume":"54","author":"Barkley","year":"2022","journal-title":"Nat Genet"},{"key":"key20260915094341_b9-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"189536","DOI":"10.1016\/j.bbcan.2026.189536","article-title":"Precision cytokine modulation to overcome tumor microenvironment-driven resistance to immune checkpoint blockade","volume":"1881","author":"Wang","year":"2026","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"key20260915094341_b10-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"101378","DOI":"10.1016\/j.drup.2026.101378","article-title":"Mechanisms of therapy resistance in the tumor microenvironment: Insights from antibody array-based cytokine profiling","volume":"86","author":"Wickramasekara","year":"2026","journal-title":"Drug Resist Updat"},{"key":"key20260915094341_b11-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1002\/cac2.70008","article-title":"Pan-cancer analysis shapes the understanding of cancer biology and medicine","volume":"45","author":"Cen","year":"2025","journal-title":"Cancer Commun (Lond)"},{"key":"key20260915094341_b12-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/j.ccell.2025.05.003","article-title":"The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets","volume":"43","author":"Knol","year":"2025","journal-title":"Cancer Cell"},{"key":"key20260915094341_b13-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/s41551-025-01541-2","article-title":"Cancer biomarkers discovered using pan-cancer plasma proteomic profiling","volume":"10","author":"Bai","year":"2025","journal-title":"Nat Biomed Eng"},{"key":"key20260915094341_b14-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12943-025-02548-8","article-title":"A pan-cancer single cell landscape reveals heterogeneity and functional diversity of double-negative T cells","volume":"25","author":"Hao","year":"2026","journal-title":"Mol Cancer"},{"key":"key20260915094341_b15-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12943-024-02182-w","article-title":"Pan-cancer drivers of metastasis","volume":"24","author":"Lusby","year":"2025","journal-title":"Mol Cancer"},{"key":"key20260915094341_b16-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e113727","DOI":"10.1371\/journal.pone.0113727","article-title":"Human RAD6 promotes G1-S transition and cell proliferation through upregulation of cyclin D1 expression","volume":"9","author":"Cai","year":"2014","journal-title":"PLoS One"},{"key":"key20260915094341_b17-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1074\/mcp.M114.042168","article-title":"KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation","volume":"14","author":"Hong","year":"2015","journal-title":"Mol Cell Proteomics"},{"key":"key20260915094341_b18-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"6680","DOI":"10.1038\/onc.2017.279","article-title":"RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance","volume":"36","author":"Somasagara","year":"2017","journal-title":"Oncogene"},{"key":"key20260915094341_b19-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1038\/s41594-023-01192-4","article-title":"UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4","volume":"31","author":"Barnsby-Greer","year":"2024","journal-title":"Nat Struct Mol Biol"},{"key":"key20260915094341_b20-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"536","DOI":"10.3109\/10799893.2014.969375","article-title":"Homology modeling and virtual screening of ubiquitin conjugation enzyme E2A for designing a novel selective antagonist against cancer","volume":"35","author":"Ramatenki","year":"2015","journal-title":"J Recept Signal Transduct Res"},{"key":"key20260915094341_b21-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.3324\/haematol.2017.179937","article-title":"De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways","volume":"104","author":"Magistroni","year":"2019","journal-title":"Haematologica"},{"key":"key20260915094341_b22-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1038\/s41420-022-00866-0","article-title":"The circular RNA hsa_circ_0001394 promotes hepatocellular carcinoma progression by targeting the miR-527\/UBE2A axis","volume":"8","author":"Yan","year":"2022","journal-title":"Cell Death Discov"},{"key":"key20260915094341_b23-mmr-34-4-13970","article-title":"ggplot2: Elegant Graphics for Data Analysis","author":"Wickham","year":"2016"},{"key":"key20260915094341_b24-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e238","DOI":"10.1002\/imt2.238","article-title":"Sangerbox 2: Enhanced functionalities and update for a comprehensive clinical bioinformatics data analysis platform","volume":"3","author":"Chen","year":"2024","journal-title":"Imeta"},{"key":"key20260915094341_b25-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e63204","DOI":"10.1371\/journal.pone.0063204","article-title":"Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women","volume":"8","author":"Colak","year":"2013","journal-title":"PLoS One"},{"key":"key20260915094341_b26-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1158\/0008-5472.CAN-12-2633","article-title":"Polo-like kinase 1: A potential therapeutic option in combination with conventional chemotherapy for the management of patients with triple-negative breast cancer","volume":"73","author":"Maire","year":"2012","journal-title":"Cancer Res"},{"key":"key20260915094341_b27-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"4200","DOI":"10.1093\/bioinformatics\/btz210","article-title":"TISIDB: An integrated repository portal for tumor-immune system interactions","volume":"35","author":"Ru","year":"2019","journal-title":"Bioinformatics"},{"key":"key20260915094341_b28-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1471-2105-12-77","article-title":"pROC: An open-source package for R and S+ to analyze and compare ROC curves","volume":"12","author":"Robin","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"key20260915094341_b29-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"W556","DOI":"10.1093\/nar\/gkz430","article-title":"GEPIA2: An enhanced web server for large-scale expression profiling and interactive analysis","volume":"47","author":"Tang","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"key20260915094341_b30-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e27633","DOI":"10.2196\/27633","article-title":"Web-based survival analysis tool tailored for medical research (KMplot): Development and implementation","volume":"23","author":"L\u00e1nczky","year":"2021","journal-title":"J Med Internet Res"},{"key":"key20260915094341_b31-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"pl1","DOI":"10.1126\/scisignal.2004088","article-title":"Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal","volume":"6","author":"Gao","year":"2013","journal-title":"Sci Signal"},{"key":"key20260915094341_b32-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"D956","DOI":"10.1093\/nar\/gkx1090","article-title":"LinkedOmics: Analyzing multi-omics data within and across 32 cancer types","volume":"46","author":"Vasaikar","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"key20260915094341_b33-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"bat054","DOI":"10.1093\/database\/bat054","article-title":"A guide to best practices for Gene Ontology (GO) manual annotation","volume":"2013","author":"Balakrishnan","year":"2013","journal-title":"Database (Oxford)"},{"key":"key20260915094341_b34-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key20260915094341_b35-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: An R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"key":"key20260915094341_b36-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"W60","DOI":"10.1093\/nar\/gky311","article-title":"GeneMANIA update 2018","volume":"46","author":"Franz","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"key20260915094341_b37-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"108640","DOI":"10.1016\/j.pharmthera.2024.108640","article-title":"Therapeutic targeting of DNA methylation alterations in cancer","volume":"258","author":"Lee","year":"2024","journal-title":"Pharmacol Ther"},{"key":"key20260915094341_b38-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"189337","DOI":"10.1016\/j.bbcan.2025.189337","article-title":"RNA methylation: A new promising biomaker in cancer liquid biopsy","volume":"1880","author":"Xu","year":"2025","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"key20260915094341_b39-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.neo.2022.01.001","article-title":"UALCAN: An update to the integrated cancer data analysis platform","volume":"25","author":"Chandrashekar","year":"2022","journal-title":"Neoplasia"},{"key":"key20260915094341_b40-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nmeth.3337","article-title":"Robust enumeration of cell subsets from tissue expression profiles","volume":"12","author":"Newman","year":"2015","journal-title":"Nat Methods"},{"key":"key20260915094341_b41-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e108","DOI":"10.1158\/0008-5472.CAN-17-0307","article-title":"TIMER: A web server for comprehensive analysis of tumor-infiltrating immune cells","volume":"77","author":"Li","year":"2017","journal-title":"Cancer Res"},{"key":"key20260915094341_b42-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/978-1-0716-0327-7_17","article-title":"EPIC: A tool to estimate the proportions of different cell types from bulk gene expression data","volume":"2120","author":"Racle","year":"2020","journal-title":"Methods Mol Biol"},{"key":"key20260915094341_b43-mmr-34-4-13970","first-page":"261","article-title":"Deconvoluting tumor-infiltrating immune cells from RNA-seq data using quanTIseq","volume":"636","author":"Plattner","year":"2019","journal-title":"Methods Enzymol"},{"key":"key20260915094341_b44-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s13059-017-1349-1","article-title":"xCell: Digitally portraying the tissue cellular heterogeneity landscape","volume":"18","author":"Aran","year":"2017","journal-title":"Genome Biol"},{"key":"key20260915094341_b45-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"D1425","DOI":"10.1093\/nar\/gkac959","article-title":"TISCH2: Expanded datasets and new tools for single-cell transcriptome analyses of the tumor micro-environment","volume":"51","author":"Han","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"key20260915094341_b46-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1016\/j.cell.2018.05.060","article-title":"Single-cell map of diverse immune phenotypes in the breast tumor microenvironment","volume":"174","author":"Azizi","year":"2018","journal-title":"Cell"},{"key":"key20260915094341_b47-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1038\/s41591-018-0078-7","article-title":"Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis","volume":"24","author":"Savas","year":"2018","journal-title":"Nat Med"},{"key":"key20260915094341_b48-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/s41587-020-00795-2","article-title":"Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes","volume":"39","author":"Gao","year":"2021","journal-title":"Nat Biotechnol"},{"key":"key20260915094341_b49-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1038\/s41588-021-00911-1","article-title":"A single-cell and spatially resolved atlas of human breast cancers","volume":"53","author":"Wu","year":"2021","journal-title":"Nat Genet"},{"key":"key20260915094341_b50-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20260915094341_b51-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e010486","DOI":"10.1136\/jitc-2024-010486","article-title":"Super-high tumor mutational burden predicts complete remission following immunotherapy: From Peto's paradox to druggable cancer hallmark","volume":"13","author":"Zheng","year":"2025","journal-title":"J Immunother Cancer"},{"key":"key20260915094341_b52-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1007\/s00262-025-03980-x","article-title":"Microsatellite instability-high status as a pan-cancer biomarker for immunotherapy efficacy","volume":"74","author":"Landre","year":"2025","journal-title":"Cancer Immunol Immunother"},{"key":"key20260915094341_b53-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s13045-025-01722-1","article-title":"Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance","volume":"18","author":"Cheng","year":"2025","journal-title":"J Hematol Oncol"},{"key":"key20260915094341_b54-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1016\/j.ccell.2024.08.005","article-title":"Cancer cell states: Lessons from ten years of single-cell RNA-sequencing of human tumors","volume":"42","author":"Tirosh","year":"2024","journal-title":"Cancer Cell"},{"key":"key20260915094341_b55-mmr-34-4-13970","first-page":"12","article-title":"Cancer statistics, 2024","volume":"74","author":"Siegel","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"key20260915094341_b56-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/cac2.12627","article-title":"Cancer situation in China: An analysis based on the global epidemiological data released in 2024","volume":"45","author":"Diao","year":"2025","journal-title":"Cancer Commun (Lond)"},{"key":"key20260915094341_b57-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1186\/s12964-024-01643-5","article-title":"Signaling, cancer cell plasticity, and intratumor heterogeneity","volume":"22","author":"Cordani","year":"2024","journal-title":"Cell Commun Signal"},{"key":"key20260915094341_b58-mmr-34-4-13970","first-page":"7362","article-title":"High expression of ubiquitin-conjugating enzyme E2A predicts poor prognosis in hepatocellular carcinoma","volume":"15","author":"Shen","year":"2018","journal-title":"Oncol Lett"},{"key":"key20260915094341_b59-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1089\/dna.2020.5823","article-title":"Increased expression of UBE2T predicting poor survival of epithelial ovarian cancer: Based on comprehensive analysis of UBE2s, clinical samples, and the GEO database","volume":"40","author":"Zou","year":"2021","journal-title":"DNA Cell Biol"},{"key":"key20260915094341_b60-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"439205","DOI":"10.1155\/2014\/439205","article-title":"Melanoma development and progression are associated with Rad6 Upregulation and \u03b2-catenin relocation to the cell membrane","volume":"2014","author":"Rosner","year":"2014","journal-title":"J Skin Cancer"},{"key":"key20260915094341_b61-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1111\/bjh.16744","article-title":"Development of an RNA sequencing-based prognostic gene signature in multiple myeloma","volume":"192","author":"Zamani-Ahmadmahmudi","year":"2021","journal-title":"Br J Haematol"},{"key":"key20260915094341_b62-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1038\/s41576-018-0074-2","article-title":"Clinical epigenetics: Seizing opportunities for translation","volume":"20","author":"Berdasco","year":"2018","journal-title":"Nat Rev Genet"},{"key":"key20260915094341_b63-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1038\/s41418-022-00962-9","article-title":"Should mutant TP53 be targeted for cancer therapy?","volume":"29","author":"Wang","year":"2022","journal-title":"Cell Death Differ"},{"key":"key20260915094341_b64-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/s41586-025-08931-1","article-title":"Targeting the SHOC2-RAS interaction in RAS-mutant cancers","volume":"642","author":"Hauseman","year":"2025","journal-title":"Nature"},{"key":"key20260915094341_b65-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"2544","DOI":"10.1182\/blood-2013-12-546309","article-title":"Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients","volume":"124","author":"de Miranda","year":"2014","journal-title":"Blood"},{"key":"key20260915094341_b66-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.ccell.2023.02.016","article-title":"The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth","volume":"41","author":"de Visser","year":"2023","journal-title":"Cancer Cell"},{"key":"key20260915094341_b67-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"e2417593","DOI":"10.1002\/advs.202417593","article-title":"Immunotyping the tumor microenvironment reveals molecular heterogeneity for personalized immunotherapy in cancer","volume":"12","author":"Zeng","year":"2025","journal-title":"Adv Sci (Weinh)"},{"key":"key20260915094341_b68-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"2818","DOI":"10.1038\/s41467-024-46735-5","article-title":"CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer","volume":"15","author":"Cheng","year":"2024","journal-title":"Nat Commun"},{"key":"key20260915094341_b69-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1146\/annurev-immunol-090222-110914","article-title":"T cell exhaustion","volume":"42","author":"Baessler","year":"2024","journal-title":"Annu Rev Immunol"},{"key":"key20260915094341_b70-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1128\/MCB.05966-11","article-title":"RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms","volume":"32","author":"Chen","year":"2012","journal-title":"Mol Cell Biol"},{"key":"key20260915094341_b71-mmr-34-4-13970","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1128\/MCB.01044-14","article-title":"RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1","volume":"35","author":"Chen","year":"2014","journal-title":"Mol Cell Biol"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:43:48Z","timestamp":1789454628000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2026.13970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,23]]},"references-count":71,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,7,23]]}},"URL":"https:\/\/doi.org\/10.3892\/mmr.2026.13970","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,23]]}}}