{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T05:35:42Z","timestamp":1793079342973,"version":"4.5.0"},"reference-count":60,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Med Rep"],"DOI":"10.3892\/mmr.2026.14045","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:35:46Z","timestamp":1792064146000},"page":"1-15","source":"Crossref","is-referenced-by-count":0,"title":["Erbin deficiency exacerbates sepsis\u2011induced liver injury through mitochondrial ROS\/NLRP3\u2011mediated inflammatory responses"],"prefix":"10.3892","volume":"34","author":[{"given":"Jing","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Wang","sequence":"additional","affiliation":[{"name":"Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital Affiliated with Wuhan University, Wuhan, Hubei 430071, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Jing","sequence":"additional","affiliation":[{"name":"Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital Affiliated with Wuhan University, Wuhan, Hubei 430071, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemin","family":"Song","sequence":"additional","affiliation":[{"name":"Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital Affiliated with Wuhan University, Wuhan, Hubei 430071, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"key20261027073031_b1-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s00418-018-1731-4","article-title":"Bone marrow-derived mesenchymal stem cells ameliorate liver injury in a rat model of sepsis by activating Nrf2 signaling","volume":"151","author":"Selim","year":"2019","journal-title":"Histochem Cell Biol"},{"key":"key20261027073031_b2-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"key20261027073031_b3-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"498","DOI":"10.3109\/08830185.2014.889129","article-title":"The role of the liver in sepsis","volume":"33","author":"Yan","year":"2014","journal-title":"Int Rev Immunol"},{"key":"key20261027073031_b4-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"210","DOI":"10.3389\/fimmu.2020.00210","article-title":"Hepatocyte-specific deletion of AMPK\u03b11 results in worse outcomes in mice subjected to sepsis in a sex-specific manner","volume":"11","author":"Kikuchi","year":"2020","journal-title":"Front Immunol"},{"key":"key20261027073031_b5-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"182","DOI":"10.4166\/kjg.2020.75.4.182","article-title":"Liver dysfunction in sepsis","volume":"75","author":"Kim","year":"2020","journal-title":"Korean J Gastroenterol"},{"key":"key20261027073031_b6-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1080\/22221751.2022.2045876","article-title":"Metformin attenuated sepsis-related liver injury by modulating gut microbiota","volume":"11","author":"Liang","year":"2022","journal-title":"Emerg Microbes Infect"},{"key":"key20261027073031_b7-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/j.jhep.2017.05.021","article-title":"CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury","volume":"67","author":"Savio","year":"2017","journal-title":"J Hepatol"},{"key":"key20261027073031_b8-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1504223","DOI":"10.3389\/fcimb.2025.1504223","article-title":"Mechanisms of sepsis-induced acute liver injury: A comprehensive review","volume":"15","author":"Guo","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"key20261027073031_b9-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1002\/hep.24764","article-title":"Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice","volume":"55","author":"Heymann","year":"2012","journal-title":"Hepatology"},{"key":"key20261027073031_b10-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1053\/j.gastro.2011.10.039","article-title":"CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis","volume":"142","author":"Nakamoto","year":"2012","journal-title":"Gastroenterology"},{"key":"key20261027073031_b11-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"113492","DOI":"10.1016\/j.intimp.2024.113492","article-title":"Immunologic role of macrophages in sepsis-induced acute liver injury","volume":"143","author":"Xu","year":"2024","journal-title":"Int Immunopharmacol"},{"key":"key20261027073031_b12-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"4756846","DOI":"10.1155\/2018\/4756846","article-title":"Methane-rich saline ameliorates sepsis-induced acute kidney injury through anti-inflammation, antioxidative, and antiapoptosis effects by regulating endoplasmic reticulum stress","volume":"2018","author":"Jia","year":"2018","journal-title":"Oxid Med Cell Longev"},{"key":"key20261027073031_b13-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"7854389","DOI":"10.1155\/2019\/7854389","article-title":"Cx43 inhibition attenuates sepsis-induced intestinal injury via downregulating ROS transfer and the activation of the JNK1\/Sirt1\/FoxO3a signaling pathway","volume":"2019","author":"Zou","year":"2019","journal-title":"Mediators Inflamm"},{"key":"key20261027073031_b14-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1089\/ars.2014.5868","article-title":"Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation","volume":"22","author":"Zhang","year":"2015","journal-title":"Antioxid Redox Signal"},{"key":"key20261027073031_b15-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/j.tcb.2017.05.005","article-title":"Gasdermins: Effectors of pyroptosis","volume":"27","author":"Kovacs","year":"2017","journal-title":"Trends Cell Biol"},{"key":"key20261027073031_b16-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.tips.2022.04.003","article-title":"NLRP3 and pyroptosis blockers for treating inflammatory diseases","volume":"43","author":"Coll","year":"2022","journal-title":"Trends Pharmacol Sci"},{"key":"key20261027073031_b17-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"101781","DOI":"10.1016\/j.smim.2023.101781","article-title":"Pyroptosis-induced inflammation and tissue damage","volume":"69","author":"Vasudevan","year":"2023","journal-title":"Semin Immunol"},{"key":"key20261027073031_b18-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"2550","DOI":"10.1038\/s41467-018-04947-6","article-title":"Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity","volume":"9","author":"He","year":"2018","journal-title":"Nat Commun"},{"key":"key20261027073031_b19-mmr-34-6-14045","first-page":"5685","article-title":"Inhibition of hepatic cells pyroptosis attenuates CLP-induced acute liver injury","volume":"8","author":"Chen","year":"2016","journal-title":"Am J Transl Res"},{"key":"key20261027073031_b20-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1074\/jbc.C200571200","article-title":"Novel mode of ligand recognition by the Erbin PDZ domain","volume":"278","author":"Birrane","year":"2003","journal-title":"J Biol Chem"},{"key":"key20261027073031_b21-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"40301","DOI":"10.1074\/jbc.M508538200","article-title":"A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling","volume":"280","author":"McDonald","year":"2005","journal-title":"J Biol Chem"},{"key":"key20261027073031_b22-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"12035","DOI":"10.18632\/oncotarget.23925","article-title":"Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death","volume":"9","author":"Shen","year":"2018","journal-title":"Oncotarget"},{"key":"key20261027073031_b23-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1083\/jcb.201411104","article-title":"Erbin is a novel substrate of the Sag-\u03b2TrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis","volume":"209","author":"Xie","year":"2015","journal-title":"J Cell Biol"},{"key":"key20261027073031_b24-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1089\/ars.2014.5994","article-title":"Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?","volume":"22","author":"Abais","year":"2015","journal-title":"Antioxid Redox Signal"},{"key":"key20261027073031_b25-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1258\/la.2010.010031","article-title":"A guide to defining and implementing protocols for the welfare assessment of laboratory animals: Eleventh report of the BVAAWF\/FRAME\/RSPCA\/UFAW Joint working group on refinement","volume":"45","author":"Hawkins","year":"2011","journal-title":"Lab Anim"},{"key":"key20261027073031_b26-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"e3000410","DOI":"10.1371\/journal.pbio.3000410","article-title":"The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research","volume":"18","author":"Percie du Sert","year":"2020","journal-title":"PLoS Biol"},{"key":"key20261027073031_b27-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/nprot.2008.214","article-title":"Immunodesign of experimental sepsis by cecal ligation and puncture","volume":"4","author":"Rittirsch","year":"2009","journal-title":"Nat Protoc"},{"key":"key20261027073031_b28-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.redox.2018.10.019","article-title":"Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress","volume":"20","author":"Bi","year":"2019","journal-title":"Redox Biol"},{"key":"key20261027073031_b29-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"e152401","DOI":"10.1172\/JCI152401","article-title":"BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils","volume":"133","author":"Tsuji","year":"2023","journal-title":"J Clin Invest"},{"key":"key20261027073031_b30-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s12974-023-02756-3","article-title":"HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy","volume":"20","author":"Yin","year":"2023","journal-title":"J Neuroinflammation"},{"key":"key20261027073031_b31-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1111\/bph.13397","article-title":"Genipin alleviates sepsis-induced liver injury by restoring autophagy","volume":"173","author":"Cho","year":"2016","journal-title":"Br J Pharmacol"},{"key":"key20261027073031_b32-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/j.jare.2024.04.004","article-title":"FGF21 ameliorates septic liver injury by restraining proinflammatory macrophages activation through the autophagy\/HIF-1\u03b1 axis","volume":"69","author":"Zhu","year":"2025","journal-title":"J Adv Res"},{"key":"key20261027073031_b33-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"100532","DOI":"10.1016\/j.jhepr.2022.100532","article-title":"Novel role of macrophage TXNIP-mediated CYLD-NRF2-OASL1 axis in stress-induced liver inflammation and cell death","volume":"4","author":"Zhan","year":"2022","journal-title":"JHEP Rep"},{"key":"key20261027073031_b34-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"115088","DOI":"10.1016\/j.intimp.2025.115088","article-title":"Macrophages Atp6v0d2 regulates XBP1-mediated cholesterol metabolism to suppress metabolic dysfunction-associated steatohepatitis progression","volume":"161","author":"Wang","year":"2025","journal-title":"Int Immunopharmacol"},{"key":"key20261027073031_b35-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s00018-022-04138-z","article-title":"PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages","volume":"79","author":"Chiu","year":"2022","journal-title":"Cell Mol Life Sci"},{"key":"key20261027073031_b36-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"7067619","DOI":"10.1155\/2019\/7067619","article-title":"Methane alleviates acetaminophen-induced liver injury by inhibiting inflammation, oxidative stress, endoplasmic reticulum stress, and apoptosis through the Nrf2\/HO-1\/NQO1 signaling pathway","volume":"2019","author":"Feng","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"key20261027073031_b37-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"154937","DOI":"10.1016\/j.phymed.2023.154937","article-title":"Aqueous extract of Polygala japonica Houtt. ameliorated nonalcoholic steatohepatitis in mice through restoring the gut microbiota disorders and affecting the metabolites in feces and liver","volume":"118","author":"Liao","year":"2023","journal-title":"Phytomedicine"},{"key":"key20261027073031_b38-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20261027073031_b39-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"3710","DOI":"10.1038\/s41467-026-70466-4","article-title":"DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis","volume":"17","author":"Luo","year":"2026","journal-title":"Nat Commun"},{"key":"key20261027073031_b40-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"e70054","DOI":"10.1002\/ams2.70054","article-title":"mRNA-miRNA integration analysis of T-cell exhaustion in sepsis from community-acquired pneumonia","volume":"12","author":"Oda","year":"2025","journal-title":"Acute Med Surg"},{"key":"key20261027073031_b41-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"R149","DOI":"10.1186\/cc10274","article-title":"Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis","volume":"15","author":"Sutherland","year":"2011","journal-title":"Crit Care"},{"key":"key20261027073031_b42-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.jhep.2014.03.031","article-title":"Modulation of monocyte\/macrophage function: A therapeutic strategy in the treatment of acute liver failure","volume":"61","author":"Possamai","year":"2014","journal-title":"J Hepatol"},{"key":"key20261027073031_b43-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"2071","DOI":"10.3390\/cells10082071","article-title":"Cystatin C deficiency increases LPS-induced sepsis and NLRP3 inflammasome activation in mice","volume":"10","author":"Biasizzo","year":"2021","journal-title":"Cells"},{"key":"key20261027073031_b44-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"e2579","DOI":"10.1038\/cddis.2016.460","article-title":"NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages","volume":"8","author":"Liu","year":"2017","journal-title":"Cell Death Dis"},{"key":"key20261027073031_b45-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1038\/nri2725","article-title":"NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?","volume":"10","author":"Tschopp","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"key20261027073031_b46-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.1136\/gutjnl-2017-314324","article-title":"Assessment of Sepsis-3 criteria and quick SOFA in patients with cirrhosis and bacterial infections","volume":"67","author":"Piano","year":"2018","journal-title":"Gut"},{"key":"key20261027073031_b47-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/s10157-023-02364-8","article-title":"Knockout of Erbin promotes pyroptosis via regulating NLRP3\/caspase-1\/Gasdermin D pathway in sepsis-induced acute kidney injury","volume":"27","author":"Liu","year":"2023","journal-title":"Clin Exp Nephrol"},{"key":"key20261027073031_b48-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"109697","DOI":"10.1016\/j.intimp.2023.109697","article-title":"The role of NLRP3 inflammasome in sepsis: A potential therapeutic target","volume":"115","author":"He","year":"2023","journal-title":"Int Immunopharmacol"},{"key":"key20261027073031_b49-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"e21672","DOI":"10.1096\/fj.202100234R","article-title":"Transcriptional enhancement of GBP-5 by BATF aggravates sepsis-associated liver injury via NLRP3 inflammasome activation","volume":"35","author":"Guo","year":"2021","journal-title":"FASEB J"},{"key":"key20261027073031_b50-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"114863","DOI":"10.1016\/j.bcp.2021.114863","article-title":"Maresin 1 protects against lipopolysaccharide\/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response","volume":"195","author":"Yang","year":"2022","journal-title":"Biochem Pharmacol"},{"key":"key20261027073031_b51-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1002\/hep.30361","article-title":"Intestinal microbiota mediates the susceptibility to polymicrobial sepsis-induced liver injury by granisetron generation in mice","volume":"69","author":"Gong","year":"2019","journal-title":"Hepatology"},{"key":"key20261027073031_b52-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"1269747","DOI":"10.1155\/2022\/1269747","article-title":"PPAR\u03b3 alleviates sepsis-induced liver injury by inhibiting hepatocyte pyroptosis via inhibition of the ROS\/TXNIP\/NLRP3 signaling pathway","volume":"2022","author":"Li","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"key20261027073031_b53-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1093\/bja\/aer093","article-title":"Oxidative stress and mitochondrial dysfunction in sepsis","volume":"107","author":"Galley","year":"2011","journal-title":"Br J Anaesth"},{"key":"key20261027073031_b54-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nri3452","article-title":"Activation and regulation of the inflammasomes","volume":"13","author":"Latz","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"key20261027073031_b55-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"107094","DOI":"10.1016\/j.intimp.2020.107094","article-title":"Z-Guggulsterone alleviated oxidative stress and inflammation through inhibiting the TXNIP\/NLRP3 axis in ischemic stroke","volume":"89","author":"Liu","year":"2020","journal-title":"Int Immunopharmacol"},{"key":"key20261027073031_b56-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.redox.2018.02.013","article-title":"Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis","volume":"16","author":"Han","year":"2018","journal-title":"Redox Biol"},{"key":"key20261027073031_b57-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12974-018-1077-9","article-title":"IRE1\u03b1 inhibition decreased TXNIP\/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic-ischemic brain injury in rats","volume":"15","author":"Chen","year":"2018","journal-title":"J Neuroinflammation"},{"key":"key20261027073031_b58-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"105122","DOI":"10.1016\/j.phrs.2020.105122","article-title":"MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH","volume":"161","author":"Chen","year":"2020","journal-title":"Pharmacol Res"},{"key":"key20261027073031_b59-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1038\/ni.1831","article-title":"Thioredoxin-interacting protein links oxidative stress to inflammasome activation","volume":"11","author":"Zhou","year":"2010","journal-title":"Nat Immunol"},{"key":"key20261027073031_b60-mmr-34-6-14045","doi-asserted-by":"publisher","first-page":"101936","DOI":"10.1016\/j.redox.2021.101936","article-title":"MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism","volume":"41","author":"Cen","year":"2021","journal-title":"Redox Biol"}],"container-title":["Molecular Medicine Reports"],"original-title":[],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T05:30:40Z","timestamp":1793079040000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/mmr.2026.14045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":60,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,10,15]]}},"URL":"https:\/\/doi.org\/10.3892\/mmr.2026.14045","relation":{},"ISSN":["1791-2997","1791-3004"],"issn-type":[{"value":"1791-2997","type":"print"},{"value":"1791-3004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]}}}