{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T01:05:25Z","timestamp":1769043925481,"version":"3.49.0"},"reference-count":39,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.3892\/ol.2015.2853","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T08:17:44Z","timestamp":1420618664000},"page":"1073-1080","source":"Crossref","is-referenced-by-count":30,"title":["Aspirin for the primary prevention of skin cancer: A meta-analysis"],"prefix":"10.3892","volume":"9","author":[{"given":"YUN","family":"ZHU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YANG","family":"CHENG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RONG-CHENG","family":"LUO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AI-MIN","family":"LI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,1,7]]},"reference":[{"key":"key20180108102641_b1-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"12222","DOI":"10.3390\/ijms140612222","article-title":"UV radiation and the skin","volume":"14","author":"D\u2019Orazio","year":"2013","journal-title":"Int J Mol Sci"},{"key":"key20180108102641_b2-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1002\/1097-0142(19950115)75:2+<607::AID-CNCR2820751402>3.0.CO;2-8","article-title":"An overview of skin cancers. Incidence and causation","volume":"75","author":"Marks","year":"1995","journal-title":"Cancer"},{"key":"key20180108102641_b3-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s13671-012-0035-5","article-title":"Update on the Epidemiology of Melanoma","volume":"2","author":"Chen","year":"2013","journal-title":"Curr Dermatol Rep"},{"issue":"Suppl 6","key":"key20180108102641_b4-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"vi1","DOI":"10.1093\/annonc\/mdp252","article-title":"Epidemiology of invasive cutaneous melanoma","volume":"20","author":"MacKie","year":"2009","journal-title":"Ann Oncol"},{"key":"key20180108102641_b5-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1358\/dot.2005.41.1.875777","article-title":"The causes of skin cancer: a comprehensive review","volume":"41","author":"Saladi","year":"2005","journal-title":"Drugs Today (Barc)"},{"key":"key20180108102641_b6-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1542\/peds.2010-3502","article-title":"Ultraviolet radiation: a hazard to children and adolescents","volume":"127","author":"Balk","year":"2011","journal-title":"Pediatrics"},{"key":"key20180108102641_b7-ol-09-03-1073","first-page":"283","article-title":"Skin cancer prevention","volume":"11","author":"Kornek","year":"2013","journal-title":"J Dtsch Dermatol Ges"},{"key":"key20180108102641_b8-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/carcin\/19.5.723","article-title":"COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer","volume":"19","author":"Buckman","year":"1998","journal-title":"Carcinogenesis"},{"key":"key20180108102641_b9-ol-09-03-1073","first-page":"3","article-title":"Molecular pathology of cyclooxygenase-2 in neoplasia","volume":"30","author":"Fosslien","year":"2000","journal-title":"Ann Clin Lab Sci"},{"key":"key20180108102641_b10-ol-09-03-1073","first-page":"303","article-title":"Expression of cyclooxygenase 2 in human malignant melanoma","volume":"61","author":"Denkert","year":"2001","journal-title":"Cancer Res"},{"key":"key20180108102641_b11-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/j.1365-2133.2004.06214.x","article-title":"Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases","volume":"151","author":"Nijsten","year":"2004","journal-title":"Br J Dermatol"},{"key":"key20180108102641_b12-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2174\/1568009043481632","article-title":"NSAIDs and chemoprevention","volume":"4","author":"Rao","year":"2004","journal-title":"Curr Cancer Drug Targets"},{"key":"key20180108102641_b13-ol-09-03-1073","first-page":"559","article-title":"Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: a critical review of non-selective COX-2 blockade (review)","volume":"13","author":"Harris","year":"2005","journal-title":"Oncol Rep"},{"key":"key20180108102641_b14-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"4047","DOI":"10.2174\/138161212802083699","article-title":"Non-aspirin non-steroidal anti-inflammatory drugs for the primary chemoprevention of non-gastrointestinal cancer: summary of evidence","volume":"18","author":"Silva","year":"2012","journal-title":"Curr Pharm Des"},{"key":"key20180108102641_b15-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1136\/bmj.321.7276.1591","article-title":"The discovery of aspirin: a reappraisal","volume":"321","author":"Sneader","year":"2000","journal-title":"BMJ"},{"key":"key20180108102641_b16-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1001\/archdermatol.2009.374","article-title":"Association between nonsteroidal anti-inflammatory drug use and cutaneous squamous cell carcinoma","volume":"146","author":"Asgari","year":"2010","journal-title":"Arch Dermatol"},{"key":"key20180108102641_b17-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/jnci\/djn154","article-title":"A large cohort study of nonsteroidal anti-inflammatory drug use and melanoma incidence","volume":"100","author":"Asgari","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"key20180108102641_b18-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1002\/ijc.26286","article-title":"Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States Radiologic Technologists study","volume":"130","author":"Cahoon","year":"2012","journal-title":"Int J Cancer"},{"key":"key20180108102641_b19-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1038\/jid.2011.58","article-title":"Long-term use of nonsteroidal anti-inflammatory drugs decreases the risk of cutaneous melanoma: results of a United States case-control study","volume":"131","author":"Curiel-Lewandrowski","year":"2011","journal-title":"J Invest Dermatol"},{"key":"key20180108102641_b20-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1002\/cncr.27817","article-title":"Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women\u2019s Health Initiative","volume":"119","author":"Gamba","year":"2013","journal-title":"Cancer"},{"key":"key20180108102641_b21-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1093\/jnci\/djk132","article-title":"A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence","volume":"99","author":"Jacobs","year":"2007","journal-title":"J Natl Cancer Inst"},{"key":"key20180108102641_b22-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"598571","DOI":"10.1155\/2011\/598571","article-title":"Nonsteroidal anti-inflammatory drugs and risk of melanoma","volume":"2011","author":"Jeter","year":"2011","journal-title":"J Skin Cancer"},{"key":"key20180108102641_b23-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1007\/s10552-012-0019-6","article-title":"Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses\u2019 Health Study","volume":"23","author":"Jeter","year":"2012","journal-title":"Cancer Causes Control"},{"key":"key20180108102641_b24-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1002\/cncr.27406","article-title":"Nonsteroidal anti-inflammatory drugs and the risk of skin cancer: a population-based case-control study","volume":"118","author":"Johannesdottir","year":"2012","journal-title":"Cancer"},{"key":"key20180108102641_b25-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1038\/jid.2009.201","article-title":"Non-steroidal anti-inflammatory drugs and melanoma risk: large Dutch population-based case-control study","volume":"129","author":"Joosse","year":"2009","journal-title":"J Invest Dermatol"},{"key":"key20180108102641_b26-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jaad.2010.05.042","article-title":"Analgesic and nonsteroidal anti-inflammatory use in relation to nonmelanoma skin cancer: a population-based case-control study","volume":"65","author":"Torti","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"key20180108102641_b27-ol-09-03-1073","unstructured":"WellsGASheaBO\u2019ConnellDThe Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analysesDepartment of Epidemiology and Community Medicine, University of OttawaCanadahttp:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.htmAccessed October 12, 2007"},{"key":"key20180108102641_b28-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"key20180108102641_b29-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"key20180108102641_b30-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"key20180108102641_b31-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"key20180108102641_b32-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1001\/jama.294.6.681","article-title":"Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years","volume":"294","author":"Christenson","year":"2005","journal-title":"JAMA"},{"key":"key20180108102641_b33-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1562\/0031-8655(2002)076<0073:CEIMAH>2.0.CO;2","article-title":"Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches","volume":"76","author":"An","year":"2002","journal-title":"Photochem Photobiol"},{"key":"key20180108102641_b34-ol-09-03-1073","first-page":"1335","article-title":"Nonsteroidal anti-inflammatory drug use in the prevention and treatment of squamous cell carcinoma","volume":"30","author":"Asgari","year":"2004","journal-title":"Dermatol Surg"},{"key":"key20180108102641_b35-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1159\/000071367","article-title":"Cyclooxygenase-2 and skin carcinogenesis","volume":"37","author":"F\u00fcrstenberger","year":"2003","journal-title":"Prog Exp Tumor Res"},{"key":"key20180108102641_b36-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/jnci\/djn485","article-title":"Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials","volume":"101","author":"Cole","year":"2009","journal-title":"J Natl Cancer Inst"},{"key":"key20180108102641_b37-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10549-010-1074-x","article-title":"Effect of aspirin and other NSAIDs on postmenopausal breast cancer incidence by hormone receptor status: results from a prospective cohort study","volume":"126","author":"Bardia","year":"2011","journal-title":"Breast Cancer Res Treat"},{"key":"key20180108102641_b38-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1200\/JCO.2012.42.2006","article-title":"Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and postmenopausal breast cancer incidence","volume":"30","author":"Zhang","year":"2012","journal-title":"J Clin Oncol"},{"key":"key20180108102641_b39-ol-09-03-1073","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/S0140-6736(11)61049-0","article-title":"CAPP2 Investigators: Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial","volume":"378","author":"Burn","year":"2011","journal-title":"Lancet"}],"container-title":["Oncology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ol.2015.2853\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T13:18:51Z","timestamp":1515417531000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ol.2015.2853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,7]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,1,7]]},"published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.3892\/ol.2015.2853"],"URL":"https:\/\/doi.org\/10.3892\/ol.2015.2853","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,7]]}}}