{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:51:13Z","timestamp":1782255073703,"version":"3.54.5"},"reference-count":38,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.3892\/ol.2016.4079","type":"journal-article","created":{"date-parts":[[2016,1,7]],"date-time":"2016-01-07T10:49:27Z","timestamp":1452163767000},"page":"1345-1352","source":"Crossref","is-referenced-by-count":8,"title":["Clinical correlation of calpain-1 and glypican-3 expression with gallbladder carcinoma"],"prefix":"10.3892","volume":"11","author":[{"given":"WEIQING","family":"LUO","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZHIGANG","family":"REN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SHENG","family":"GAO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HAILONG","family":"JIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GEER","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LIN","family":"ZHOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SHUSEN","family":"ZHENG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2016,1,7]]},"reference":[{"key":"key20180108095057_b1-ol-0-0-4079","first-page":"99","article-title":"Gallbladder cancer: Epidemiology and outcome","volume":"6","author":"Hundal","year":"2014","journal-title":"Clin Epidemiol"},{"key":"key20180108095057_b2-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"E359","DOI":"10.1002\/ijc.29210","article-title":"Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012","volume":"136","author":"Ferlay","year":"2015","journal-title":"Int J Cancer"},{"key":"key20180108095057_b3-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1002\/1097-0142(19920915)70:6<1493::AID-CNCR2820700608>3.0.CO;2-U","article-title":"Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates","volume":"70","author":"Henson","year":"1992","journal-title":"Cancer"},{"key":"key20180108095057_b4-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/MOG.0000000000000068","article-title":"Aspects on gallbladder cancer in 2014","volume":"30","author":"\u00c5ndr\u00e9n-Sandberg","year":"2014","journal-title":"Curr Opin Gastroenterol"},{"key":"key20180108095057_b5-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1572-0241.2000.02070.x","article-title":"Primary gallbladder cancer: Recognition of risk factors and the role of prophylactic cholecystectomy","volume":"95","author":"Sheth","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"key20180108095057_b6-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1470-2045(03)01021-0","article-title":"Carcinoma of the gallbladder","volume":"4","author":"Misra","year":"2003","journal-title":"Lancet Oncol"},{"key":"key20180108095057_b7-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1111\/j.1742-4658.2006.05353.x","article-title":"The structural basis of calpain behavior","volume":"273","author":"Benyamin","year":"2006","journal-title":"FEBS J"},{"key":"key20180108095057_b8-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1002\/ijc.25832","article-title":"Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy","volume":"129","author":"Storr","year":"2011","journal-title":"Int J Cancer"},{"key":"key20180108095057_b9-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S1471-4914(01)02049-4","article-title":"The calpain family and human disease","volume":"7","author":"Huang","year":"2001","journal-title":"Trends Mol Med"},{"key":"key20180108095057_b10-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1006\/geno.1998.5395","article-title":"SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia)","volume":"51","author":"Kamei","year":"1998","journal-title":"Genomics"},{"key":"key20180108095057_b11-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.ejca.2010.10.024","article-title":"Glypican-3: A new target for cancer immunotherapy","volume":"47","author":"Ho","year":"2011","journal-title":"Eur J Cancer"},{"key":"key20180108095057_b12-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"6245","DOI":"10.1158\/0008-5472.CAN-04-4244","article-title":"Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling","volume":"65","author":"Capurro","year":"2005","journal-title":"Cancer Res"},{"key":"key20180108095057_b13-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.devcel.2008.03.006","article-title":"Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding","volume":"14","author":"Capurro","year":"2008","journal-title":"Dev Cell"},{"key":"key20180108095057_b14-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1002\/ijc.24941","article-title":"Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo","volume":"126","author":"Zittermann","year":"2010","journal-title":"Int J Cancer"},{"key":"key20180108095057_b15-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1002\/ijc.25549","article-title":"Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro","volume":"128","author":"Feng","year":"2011","journal-title":"Int J Cancer"},{"key":"key20180108095057_b16-ol-0-0-4079","first-page":"5179","article-title":"Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: Biological significance and temporospatial distribution","volume":"57","author":"Hsu","year":"1997","journal-title":"Cancer Res"},{"key":"key20180108095057_b17-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"6612","DOI":"10.1158\/1078-0432.CCR-04-0348","article-title":"Identification of glypican-3 as a novel tumor marker for melanoma","volume":"10","author":"Nakatsura","year":"2004","journal-title":"Clin Cancer Res"},{"key":"key20180108095057_b18-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/pgp.0b013e31802d692c","article-title":"Glypican-3 expression in primary and recurrent ovarian carcinomas","volume":"26","author":"Stadlmann","year":"2007","journal-title":"Int J Gynecol Pathol"},{"key":"key20180108095057_b19-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1097\/01.pas.0000213322.89670.48","article-title":"Glypican 3: A novel marker in testicular germ cell tumors","volume":"30","author":"Zynger","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"key20180108095057_b20-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1309\/HCQWPWD50XHD2DW6","article-title":"Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: A tissue microarray analysis of 4,387 tissue samples","volume":"129","author":"Baumhoer","year":"2008","journal-title":"Am J Clin Pathol"},{"key":"key20180108095057_b21-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/1097-0215(20000920)89:5<418::AID-IJC4>3.0.CO;2-I","article-title":"Expression of glypican 3 (GPC3) in embryonal tumors","volume":"89","author":"Saikali","year":"2000","journal-title":"Int J Cancer"},{"key":"key20180108095057_b22-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/ncponc0252","article-title":"Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: REporting recommendations for tumor MARKer prognostic studies (REMARK)","volume":"2","author":"McShane","year":"2005","journal-title":"Nat Clin Pract Oncol"},{"key":"key20180108095057_b23-ol-0-0-4079","first-page":"211","article-title":"Gallbladder","author":"Edge","year":"2010","journal-title":"AJCC Cancer Staging Manual"},{"key":"key20180108095057_b24-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"e183","DOI":"10.1016\/j.suronc.2012.08.002","article-title":"Gallbladder cancer: Past, present and an uncertain future","volume":"21","author":"Boutros","year":"2012","journal-title":"Surg Oncol"},{"key":"key20180108095057_b25-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/1354750X.2012.717105","article-title":"Potential biomarkers in gallbladder cancer: Present status and future directions","volume":"18","author":"Srivastava","year":"2013","journal-title":"Biomarkers"},{"key":"key20180108095057_b26-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"4085","DOI":"10.3748\/wjg.v20.i14.4085","article-title":"Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer","volume":"20","author":"Wang","year":"2014","journal-title":"World J Gastroenterol"},{"key":"key20180108095057_b27-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1038\/onc.2009.422","article-title":"Calpain regulates sensitivity to trastuzumab and survival in HER2-positive breast cancer","volume":"29","author":"Kulkarni","year":"2010","journal-title":"Oncogene"},{"key":"key20180108095057_b28-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1093\/annonc\/mds176","article-title":"Calpain system protein expression in basal-like and triple-negative invasive breast cancer","volume":"23","author":"Storr","year":"2012","journal-title":"Ann Oncol"},{"key":"key20180108095057_b29-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s00535-012-0743-4","article-title":"Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas","volume":"48","author":"Storr","year":"2013","journal-title":"J Gastroenterol"},{"key":"key20180108095057_b30-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1186\/1471-2407-12-511","article-title":"Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla","volume":"12","author":"Storr","year":"2012","journal-title":"BMC Cancer"},{"key":"key20180108095057_b31-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1517\/14728222.2013.766169","article-title":"Targeting calpain in synaptic plasticity","volume":"17","author":"Baudry","year":"2013","journal-title":"Expert Opin Ther Targets"},{"key":"key20180108095057_b32-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"8497","DOI":"10.1074\/jbc.M600787200","article-title":"Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: Identification of a novel signaling pathway","volume":"281","author":"Sawhney","year":"2006","journal-title":"J Biol Chem"},{"key":"key20180108095057_b33-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1159\/000430464","article-title":"Calpain in breast cancer: Role in disease progression and treatment response","volume":"82","author":"Storr","year":"2015","journal-title":"Pathobiology"},{"key":"key20180108095057_b34-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.abb.2014.09.018","article-title":"Calpains and cancer: Friends or enemies?","volume":"564","author":"Moretti","year":"2014","journal-title":"Arch Biochem Biophys"},{"key":"key20180108095057_b35-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"969","DOI":"10.3892\/mmr.2013.1279","article-title":"Overexpression of GPC3 inhibits hepatocellular carcinoma cell proliferation and invasion through induction of apoptosis","volume":"7","author":"Pan","year":"2013","journal-title":"Mol Med Rep"},{"key":"key20180108095057_b36-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1074\/jbc.M410090200","article-title":"The loss of glypican-3 induces alterations in Wnt signaling","volume":"280","author":"Song","year":"2005","journal-title":"J Biol Chem"},{"key":"key20180108095057_b37-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"e0143199","DOI":"10.1371\/journal.pone.0143199","article-title":"Reliably detecting clinically important variants requires both combined variant calls and optimized filtering strategies","volume":"10","author":"Field","year":"2015","journal-title":"PLoS One"},{"key":"key20180108095057_b38-ol-0-0-4079","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1186\/s12885-015-1779-7","article-title":"Circulating tumor cells (Ctc) and kras mutant circulating free Dna (cfdna) detection in peripheral blood as biomarkers in patients diagnosed with exocrine pancreatic cancer","volume":"15","author":"Earl","year":"2015","journal-title":"BMC Cancer"}],"container-title":["Oncology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/ol.2016.4079\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T17:34:18Z","timestamp":1718300058000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/ol.2016.4079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,7]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,1,7]]},"published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.3892\/ol.2016.4079"],"URL":"https:\/\/doi.org\/10.3892\/ol.2016.4079","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,7]]}}}