{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:30:03Z","timestamp":1773289803286,"version":"3.50.1"},"reference-count":37,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2018.8128","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T11:22:54Z","timestamp":1519730574000},"source":"Crossref","is-referenced-by-count":5,"title":["MicroRNA-425 is downregulated in nasopharyngeal carcinoma and regulates tumor cell viability and invasion by targeting hepatoma-derived growth factor"],"prefix":"10.3892","author":[{"given":"Wenyan","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongchi","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuqin","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"key":"key20200714003423_b1-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40880-015-0006-x","article-title":"Cancer statistics: Updated cancer burden in China","volume":"27","author":"Chen","year":"2015","journal-title":"Chin J Cancer Res"},{"key":"key20200714003423_b2-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S1462399407000312","article-title":"Nasopharyngeal carcinoma: Molecular pathogenesis and therapeutic developments","volume":"9","author":"Tao","year":"2007","journal-title":"Expert Rev Mol Med"},{"key":"key20200714003423_b3-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1097\/CCO.0b013e328344f527","article-title":"Modern treatment for nasopharyngeal carcinoma: Current status and prospects","volume":"23","author":"Rottey","year":"2011","journal-title":"Curr Opin Oncol"},{"key":"key20200714003423_b4-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1186\/1471-2407-6-178","article-title":"Trends in incidence and mortality of nasopharyngeal carcinoma over a 20\u201325 year period (1978\/1983-2002) in Sihui and Cangwu counties in southern China","volume":"6","author":"Jia","year":"2006","journal-title":"BMC Cancer"},{"key":"key20200714003423_b5-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.ijrobp.2010.03.024","article-title":"How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients?","volume":"80","author":"Lai","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key20200714003423_b6-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1002\/cncr.25754","article-title":"Local control, survival, and late toxicities of locally advanced nasopharyngeal carcinoma treated by simultaneous modulated accelerated radiotherapy combined with cisplatin concurrent chemotherapy: Long-term results of a phase 2 study","volume":"117","author":"Xiao","year":"2011","journal-title":"Cancer"},{"key":"key20200714003423_b7-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/S1470-2045(05)70172-8","article-title":"Syncope due to nasopharyngeal carcinoma","volume":"6","author":"Chen-Scarabelli","year":"2005","journal-title":"Lancet Oncol"},{"key":"key20200714003423_b8-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1038\/nature02871","article-title":"The functions of animal microRNAs","volume":"431","author":"Ambros","year":"2004","journal-title":"Nature"},{"key":"key20200714003423_b9-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1038\/nrg1379","article-title":"MicroRNAs: Small RNAs with a big role in gene regulation","volume":"5","author":"He","year":"2004","journal-title":"Nat Rev Genet"},{"key":"key20200714003423_b10-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: Target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"key20200714003423_b11-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/S0092-8674(03)00428-8","article-title":"MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing","volume":"113","author":"Ambros","year":"2003","journal-title":"Cell"},{"key":"key20200714003423_b12-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1038\/nrc1997","article-title":"MicroRNA signatures in human cancers","volume":"6","author":"Calin","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"key20200714003423_b13-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"e79584","DOI":"10.1371\/journal.pone.0079584","article-title":"Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies","volume":"8","author":"Ma","year":"2013","journal-title":"PLoS One"},{"key":"key20200714003423_b14-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/1476-4598-12-123","article-title":"miR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma","volume":"12","author":"Liu","year":"2013","journal-title":"Mol Cancer"},{"key":"key20200714003423_b15-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.3892\/ol.2014.1875","article-title":"MicroRNA-99a inhibiting cell proliferation, migration and invasion by targeting fibroblast growth factor receptor 3 in bladder cancer","volume":"7","author":"Wu","year":"2014","journal-title":"Oncol Lett"},{"key":"key20200714003423_b16-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"4379","DOI":"10.3892\/mmr.2016.5055","article-title":"MicroRNA-335 is downregulated in bladder cancer and inhibits cell growth, migration and invasion via targeting ROCK1","volume":"13","author":"Wu","year":"2016","journal-title":"Mol Med Rep"},{"key":"key20200714003423_b17-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1517\/14712598.7.7.1009","article-title":"Regulatory mechanisms of microRNAs involvement in cancer","volume":"7","author":"Fabbri","year":"2007","journal-title":"Expert Opin Biol Ther"},{"key":"key20200714003423_b18-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ydbio.2006.08.028","article-title":"microRNAs as oncogenes and tumor suppressors","volume":"302","author":"Zhang","year":"2007","journal-title":"Dev Biol"},{"key":"key20200714003423_b19-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.biopha.2015.08.010","article-title":"miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1","volume":"75","author":"Liu","year":"2015","journal-title":"Biomed Pharmacother"},{"key":"key20200714003423_b20-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/j.jgg.2015.09.010","article-title":"Enhanced expression of miR-425 promotes esophageal squamous cell carcinoma tumorigenesis by targeting SMAD2","volume":"42","author":"Liu","year":"2015","journal-title":"J Genet Genomics"},{"key":"key20200714003423_b21-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"2213","DOI":"10.1111\/jcmm.12902","article-title":"Potential therapeutic value of miR-425-5p in metastatic colorectal cancer","volume":"20","author":"Crist\u00f3bal","year":"2016","journal-title":"J Cell Mol Med"},{"key":"key20200714003423_b22-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"key20200714003423_b23-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"3489","DOI":"10.1002\/cam4.863","article-title":"miR-17-5p promotes cancer cell proliferation and tumorigenesis in nasopharyngeal carcinoma by targeting p21","volume":"5","author":"Chen","year":"2016","journal-title":"Cancer Med"},{"key":"key20200714003423_b24-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s12079-016-0351-9","article-title":"MicroRNA-1275 suppresses cell growth, and retards G1\/S transition in human nasopharyngeal carcinoma by down-regulation of HOXB5","volume":"10","author":"Sun","year":"2016","journal-title":"J Cell Commun Signal"},{"key":"key20200714003423_b25-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3727\/096504016X14611963142290","article-title":"MicroRNA-15a inhibits proliferation and induces apoptosis in CNE1 nasopharyngeal carcinoma cells","volume":"24","author":"Zhu","year":"2016","journal-title":"Oncol Res"},{"key":"key20200714003423_b26-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.3892\/etm.2015.2318","article-title":"microRNA-425-5p is upregulated in human gastric cancer and contributes to invasion and metastasis in vitro and in vivo","volume":"9","author":"Zhang","year":"2015","journal-title":"Exp Ther Med"},{"key":"key20200714003423_b27-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1177\/0004563216649377","article-title":"MicoRNA-425-5p is a potential prognostic biomarker for cervical cancer","volume":"54","author":"Sun","year":"2017","journal-title":"Ann Clin Biochem"},{"key":"key20200714003423_b28-ol-0-0-8128","first-page":"1889","article-title":"MiR-425 up-regulation induced by interleukin-1beta promotes the proliferation of gastric cancer cell AGS","volume":"94","author":"Liu","year":"2014","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"key20200714003423_b29-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"2675","DOI":"10.2217\/fon.14.194","article-title":"HDGF: A novel jack-of-all-trades in cancer","volume":"10","author":"Bao","year":"2014","journal-title":"Future Oncol"},{"key":"key20200714003423_b30-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1016\/j.bbrc.2004.01.151","article-title":"Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma","volume":"315","author":"Huang","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"key20200714003423_b31-ol-0-0-8128","first-page":"211","article-title":"Aberrant expression of HDGF and its prognostic values in surgically resected non-small cell lung cancer","volume":"14","author":"Zhang","year":"2011","journal-title":"Zhongguo Fei Ai Za Zhi"},{"key":"key20200714003423_b32-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1158\/1078-0432.CCR-05-1347","article-title":"Expression of hepatoma-derived growth factor is correlated with lymph node metastasis and prognosis of gastric carcinoma","volume":"12","author":"Yamamoto","year":"2006","journal-title":"Clin Cancer Res"},{"key":"key20200714003423_b33-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"21492","DOI":"10.3390\/ijms151121492","article-title":"Hepatoma-derived growth factor upregulation is correlated with prognostic factors of early-stage cervical adenocarcinoma","volume":"15","author":"Tsai","year":"2014","journal-title":"Int J Mol Sci"},{"key":"key20200714003423_b34-ol-0-0-8128","first-page":"511","article-title":"Various effects of hepatoma-derived growth factor on cell growth, migration and invasion of breast cancer and prostate cancer cells","volume":"26","author":"Guo","year":"2011","journal-title":"Oncol Rep"},{"key":"key20200714003423_b35-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1007\/s12032-013-0622-8","article-title":"The expression of hepatoma-derived growth factor in primary central nervous system lymphoma and its correlation with angiogenesis, proliferation and clinical outcome","volume":"30","author":"Li","year":"2013","journal-title":"Med Oncol"},{"key":"key20200714003423_b36-ol-0-0-8128","first-page":"6475","article-title":"Down-regulation of HDGF inhibits the growth of hepatocellular carcinoma cells in vitro and in vivo","volume":"35","author":"Enomoto","year":"2015","journal-title":"Anticancer Res"},{"key":"key20200714003423_b37-ol-0-0-8128","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/j.1365-2559.2010.03739.x","article-title":"Increased expression of hepatoma-derived growth factor correlates with poor prognosis in human nasopharyngeal carcinoma","volume":"58","author":"Wang","year":"2011","journal-title":"Histopathology"}],"updated-by":[{"DOI":"10.3892\/ol.2024.14245","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"record-id":"51487"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T01:01:36Z","timestamp":1594688496000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2018.8128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,27]]},"references-count":37,"URL":"https:\/\/doi.org\/10.3892\/ol.2018.8128","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,27]]}}}